Radboudumc 1 article published in JoVE Genetics Exploring X Chromosomal Aberrations in Ovarian Cells by Using Fluorescence In Situ Hybridization Sapthami Nadesapillai1, Janielle van der Velden2, Didi Braat1, Kathrin Fleischer1,3, Ronald Peek1 1Department of Obstetrics and Gynecology, Radboudumc, 2Department of Pediatrics, Radboudumc, Amalia Children’s Hospital, 3Department of Reproductive Medicine, Nij Geertgen Center for Fertility This article presents two methods based on fluorescence in situ hybridization to determine the X chromosomal content of ovarian cells in non-grafted and grafted ovarian cortex tissue from females with X chromosomal aberrations.