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Stroke-Preventing Technology Demonstrated in JoVE
February 28, 2012

In the United States alone, approximately 6 million people suffer from an irregular heartbeat called atrial fibrillation (AF), and since the incidence increases with age, it is predicted that 15.9 million Americans will be affected by 2050. The most devastating side effect of AF is stroke, but a new device from Boston Scientific may prevent them from occurring.
Researchers from Atritech, now part of Boston Scientific, developed the WATCHMAN device, a small mesh umbrella that can be inserted into part of the heart cavity to prevent the formation of blood clots that cause strokes.
Currently, the anti-coagulant drug warfarin is used to prevent strokes, but the drug comes with other risks.
"Warfarin has a lot of side-effects. One major side-effect is the bleeding risk," said paper author Dr. Sven Mobius-Winkler. "Therefore, only 50 percent of the patients who should take Warfarin actually take it."
The WATCHMAN device gives patients another option. It has already been approved for use in the European Union and Australia, and secured investigational approval from the FDA in 2009.
To help train doctors how to use the device, physicians from the University of Leipzig Heart Center in Germany are publishing the full WATCHMAN placement procedure in the Journal of Visualized Experiments (JoVE), the world's first and only peer-reviewed, PubMed indexed, science and medicine video journal."Intervention and closure of the left atrial appendage is a complex procedure," said Dr. Mobius-Winkler. "For inexperienced physicians, it is hard to learn this procedure and therefore the video can help by doing step-by-step the implantation."
"The WATCHMAN device will give patients with atrial fibrillation another option rather than anti-coagulant drugs," said JoVE Editor Dr. Robert Dolan. "This article demonstrates the implantation of the device and will help clinicians gain expertise with the procedure, helping many of the patients who are unable or unwilling to take warfarin."
The procedure will be published in JoVE on Feb. 28, and can be seen here: http://www.jove.com/video/3671/the-watchman-left-atrial-appendage-closure-device-for-atrial-fibrillation
About JoVE, The Journal of Visualized Experiments:
JoVE, the Journal of Visualized Experiments, is the first and only PubMed/MEDLINE-indexed, peer-reviewed journal devoted to publishing scientific research in a video format. Using an international network of videographers, JoVE films and edits videos of researchers performing new experimental techniques at top universities, allowing students and scientists to learn them much more quickly. As of May 2013, JoVE has published video-protocols from an international community of more than 8,000 authors in the fields of biology, medicine, chemistry, and physics.
URL: www.jove.com
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e. press@jove.com
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