Alain Ruffion Joint Unit Hospices de Lyon-bioMérieux Biography Publications Institution JoVE Articles Alain Ruffion has not added a biography. If you are Alain Ruffion and would like to personalize this page please email our Author Liaison for assistance. Publications Microarray Gene Expression Profiling and Analysis of Bladder Cancer Supports the Sub Classification of the T1 Tumours in T1a and T1b Stages BJU International. Jul, 2013 | Pubmed ID: 24053469 Surgical Outcomes and Patients' Satisfaction with Suprapubic Phalloplasty The Journal of Sexual Medicine. Sep, 2013 | Pubmed ID: 24024755 Prospective Study of Methods of Renal Function Evaluation in Patients With Neurogenic Bladder Dysfunction Urology. Aug, 2013 | Pubmed ID: 24001705 PCA3 and PCA3-based Nomograms Improve Diagnostic Accuracy in Patients Undergoing First Prostate Biopsy International Journal of Molecular Sciences. 2013 | Pubmed ID: 23994838 Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity Among Patients with Neurogenic Overactive Bladder Neuroepidemiology. Aug, 2013 | Pubmed ID: 23942583 Hereditary-like Urothelial Carcinomas of the Upper Urinary Tract Benefit More from Adjuvant Cisplatin-based Chemotherapy After Radical Nephroureterectomy Than Do Sporadic Tumours BJU International. Jun, 2013 | Pubmed ID: 23937547 Impact of Micropapillary Histological Variant on Survival After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma World Journal of Urology. Aug, 2013 | Pubmed ID: 23907662 Differentially Expressed Androgen-regulated Genes in Androgen-sensitive Tissues Reveal Potential Biomarkers of Early Prostate Cancer PloS One. 2013 | Pubmed ID: 23840433 Risk Stratification of Metastatic Recurrence in Invasive Upper Urinary Tract Carcinoma After Radical Nephroureterectomy Without Lymphadenectomy World Journal of Urology. Jun, 2013 | Pubmed ID: 23812497 Impact of Lymphovascular Invasion on Oncological Outcomes in Patients with Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy BJU International. Jun, 2013 | Pubmed ID: 23650914 Reply: To PMID 22984785 BJU International. Apr, 2013 | Pubmed ID: 23551451 Reply: Four-hundredfold Overestimation of Biopsy Mortality BJU International. Mar, 2013 | Pubmed ID: 23444934 Influence of Previous or Synchronous Bladder Cancer on Oncologic Outcomes After Radical Nephroureterectomy for Upper Urinary Tract Urothelialcarcinoma Urologic Oncology. Feb, 2013 | Pubmed ID: 23403206 Prostate Hypofractionated Radiation Therapy: Injection of Hyaluronic Acid to Better Preserve the Rectal Wall International Journal of Radiation Oncology, Biology, Physics. May, 2013 | Pubmed ID: 23290444 Impact of Adoption of a Decision Algorithm Including PCA3 for Repeat Biopsy on the Costs for Prostate Cancer Diagnosis in France Journal of Medical Economics. 2013 | Pubmed ID: 23231342 The Impact of Lymph Node Status and Features on Oncological Outcomes in Urothelial Carcinoma of the Upper Urinary Tract (UTUC) Treated by Nephroureterectomy World Journal of Urology. Feb, 2013 | Pubmed ID: 23229227 The Oncologic Impact of a Delay Between Diagnosis and Radical Nephroureterectomy Due to Diagnostic Ureteroscopy in Upper Urinary Tract Urothelial Carcinomas: Results from a Large Collaborative Database World Journal of Urology. Feb, 2013 | Pubmed ID: 23070533 Intravesical Recurrence After Radical Nephroureterectomy for Upper Tract Urothelial Carcinomas: Predictors and Impact on Subsequent Oncological Outcomes from a National Multicenter Study World Journal of Urology. Feb, 2013 | Pubmed ID: 23053211 Erratum To: Influence of Positive Surgical Margin Status After Radical Nephroureterectomy on Upper Urinary Tract Urothelial Carcinoma Survival Annals of Surgical Oncology. Nov, 2012 | Pubmed ID: 23161116 Critical Role of Prostate Biopsy Mortality in the Number of Years of Life Gained and Lost Within a Prostate Cancer Screening Programme BJU International. Dec, 2012 | Pubmed ID: 22984785 Influence of Positive Surgical Margin Status After Radical Nephroureterectomy on Upper Urinary Tract Urothelial Carcinoma Survival Annals of Surgical Oncology. Oct, 2012 | Pubmed ID: 22843187 A Proportion of Hereditary Upper Urinary Tract Urothelial Carcinomas Are Misclassified As Sporadic According to a Multi-institutional Database Analysis: Proposal of Patient-specific Risk Identification Tool BJU International. Dec, 2012 | Pubmed ID: 22703159 [Prostate-specific Antigen Use Among Men Without Prostate Cancer in France (2008-2010)] Bulletin Du Cancer. May, 2012 | Pubmed ID: 22525252 The Value of Urinary Prostate Cancer Gene 3 (PCA3) Scores in Predicting Pathological Features at Radical Prostatectomy BJU International. Jul, 2012 | Pubmed ID: 22221521 Can Sacral Neuromodulation Improve Minor Incontinence Symptoms in Doubly Incontinent Patients Successfully Treated for Major Incontinence Symptoms? Urology. Jan, 2012 | Pubmed ID: 22099864 Side Effects of Intradetrusor Botulinum Toxin Injections on Ejaculation and Fertility in Men with Spinal Cord Injury: Preliminary Findings BJU International. Jun, 2012 | Pubmed ID: 21981647 Down-regulation of DcR2 Sensitizes Androgen-dependent Prostate Cancer LNCaP Cells to TRAIL-induced Apoptosis Cancer Cell International. 2011 | Pubmed ID: 22136382 In Vitro Affinity Maturation of an Anti-PSA Antibody for Prostate Cancer Diagnostic Assay Journal of Molecular Biology. Dec, 2011 | Pubmed ID: 22019475 Ureteral and Multifocal Tumours Have Worse Prognosis Than Renal Pelvic Tumours in Urothelial Carcinoma of the Upper Urinary Tract Treated by Nephroureterectomy European Urology. Dec, 2011 | Pubmed ID: 21665356 TM4SF1, a Novel Primary Androgen Receptor Target Gene Over-expressed in Human Prostate Cancer and Involved in Cell Migration The Prostate. Aug, 2011 | Pubmed ID: 21656834 [Value of PCA3 Urinary Test for Prostate Biopsy Decision: the Lyon-Sud University Hospital Experience] Annales De Biologie Clinique. Jan-Feb, 2011 | Pubmed ID: 21463993 [Atypical Urothelial Cells (AUC): A Bethesda-derived Wording Applicable to Urinary Cytopathology] Annales De Pathologie. Feb, 2011 | Pubmed ID: 21349383 Urinary PCA3 Score Predicts Prostate Cancer Multifocality The Journal of Urology. Apr, 2011 | Pubmed ID: 21334023 Randomized, Crossover Study Evaluating Patient Preference and the Impact on Quality of Life of Urisheaths Vs Absorbent Products in Incontinent Men BJU International. Jul, 2011 | Pubmed ID: 20950307 Treatment of Neurogenic Male Urinary Incontinence Related to Intrinsic Sphincter Insufficiency with an Artificial Urinary Sphincter: a French Retrospective Multicentre Study BJU International. Feb, 2011 | Pubmed ID: 20633005 [Microsatellite Markers and Methylation of Promoters of Tumour Suppressor Genes in Bladder Cancer] Annales De Pathologie. Nov, 2010 | Pubmed ID: 21055568 Efficacy and Tolerability of Botulinum Toxin Type A in Patients with Neurogenic Detrusor Overactivity and Without Concomitant Anticholinergic Therapy: Comparison of Two Doses European Urology. Nov, 2010 | Pubmed ID: 20674149 Quantitative Loss of Heterozygosity Analysis for Urothelial Carcinoma Detection and Prognosis Urology. Aug, 2010 | Pubmed ID: 20206968 Urinary Prostate Cancer 3 Test: Toward the Age of Reason? Urology. Feb, 2010 | Pubmed ID: 19586654 [Isolated Testicular Mass Revealing a Metastasis of Prostate Adenocarcinoma] Annales De Pathologie. Dec, 2009 | Pubmed ID: 20005437 Prognostic Value of Modeled PSA Clearance on Biochemical Relapse Free Survival After Radical Prostatectomy The Prostate. Sep, 2009 | Pubmed ID: 19475643 Botulinum Toxin-A (Botox) Intradetrusor Injections in Children with Neurogenic Detrusor Overactivity/neurogenic Overactive Bladder: a Systematic Literature Review Journal of Pediatric Urology. Jun, 2009 | Pubmed ID: 19264554 Use of Forearm Free-flap Phalloplasty in Bladder Exstrophy Adults BJU International. May, 2009 | Pubmed ID: 19154455 Androgen Inhibits the Growth of Carcinoma Cell Lines Established from Prostate Cancer Xenografts That Escape Androgen Treatment The Journal of Steroid Biochemistry and Molecular Biology. Jul, 2008 | Pubmed ID: 18550362 Advantages of Prostate-specific Antigen (PSA) Clearance Model over Simple PSA Half-life Computation to Describe PSA Decrease After Prostate Adenomectomy Clinical Biochemistry. Jul, 2008 | Pubmed ID: 18440312 Long-term Outcome of Forearm Flee-flap Phalloplasty in the Treatment of Transsexualism BJU International. May, 2008 | Pubmed ID: 18190640 Botulinum Toxin A (Botox) Intradetrusor Injections in Adults with Neurogenic Detrusor Overactivity/neurogenic Overactive Bladder: a Systematic Literature Review European Urology. Feb, 2008 | Pubmed ID: 17988791 Association Between Sarcoidosis and Testicular Carcinoma: a Diagnostic Pitfall Sarcoidosis, Vasculitis, and Diffuse Lung Diseases : Official Journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders. Sep, 2007 | Pubmed ID: 18496978 The Neurogenic Bladder in Multiple Sclerosis: Review of the Literature and Proposal of Management Guidelines Multiple Sclerosis (Houndmills, Basingstoke, England). Aug, 2007 | Pubmed ID: 17881401 Surgical Principles of Omentoplasty in Urology BJU International. May, 2007 | Pubmed ID: 17437453 [Value of Urinary Markers in the Diagnosis and Follow-up of Urothelial Bladder Tumours] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Feb, 2007 | Pubmed ID: 17373233 [Chemical Destruction of Sacral Nerve Roots by Alcohol Injection for the Treatment of Overactive Bladder] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Nov, 2006 | Pubmed ID: 17175956 [REMEEX: A Possible Treatment Option in Selected Cases of Sphincter Incompetence] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Apr, 2006 | Pubmed ID: 16734242 [A Modified IPSS Score: Value of a Choice of Qualitative Answers] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Apr, 2006 | Pubmed ID: 16734240 Discovery of a Pituitary Adenoma Following a Gonadotropin-releasing Hormone Agonist in a Patient with Prostate Cancer International Journal of Urology : Official Journal of the Japanese Urological Association. Mar, 2006 | Pubmed ID: 16643633 What is the Optimum Dose of Type A Botulinum Toxin for Treating Neurogenic Bladder Overactivity? BJU International. May, 2006 | Pubmed ID: 16643486 [Management of Corpus Cavernosum Trauma] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Feb, 2006 | Pubmed ID: 16526533 Discovery of a Pituitary Adenoma Following Treatment with a Gonadotropin-releasing Hormone Agonist in a Patient with Prostate Cancer International Journal of Urology : Official Journal of the Japanese Urological Association. Jan, 2006 | Pubmed ID: 16448441 The Epidemiology of Trauma of the Genitourinary System After Traffic Accidents: Analysis of a Register of over 43,000 Victims BJU International. Feb, 2006 | Pubmed ID: 16430642 TNF-alpha-related Apoptosis-inducing Ligand Decoy Receptor DcR2 is Targeted by Androgen Action in the Rat Ventral Prostate Journal of Cellular Physiology. Mar, 2006 | Pubmed ID: 16245307 [Well Differentiated Paratesticular Liposarcoma in Adults] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Dec, 2005 | Pubmed ID: 16429673 [Comparison of the Response to I-PSS According to the Mode of Administration of the Questionnaire: by the Doctor or Self-assessment by the Patient] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Dec, 2005 | Pubmed ID: 16429656 [PSA Doubling Time and Method of Calculation] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Dec, 2005 | Pubmed ID: 16429649 Ex Vivo Tumorectomy on Transplanted Kidney Transplantation. Dec, 2005 | Pubmed ID: 16371938 [New Treatments for Urinary Incontinence in Adults] Soins; La Revue De Référence Infirmière. Oct, 2005 | Pubmed ID: 16279116 [Types and Mechanisms of 54 Cases of Kidney Trauma in Car Drivers Injured by Road Accident] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Jun, 2005 | Pubmed ID: 16097145 [Is Tumour Grade Applicable to Finasteride-treated Prostate Cancer?] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Jun, 2005 | Pubmed ID: 16097140 [Erectile Dysfunction] La Revue Du Praticien. Jan, 2005 | Pubmed ID: 15801402 Activation of Caspases-3, -6, and -9 During Finasteride Treatment of Benign Prostatic Hyperplasia The Journal of Clinical Endocrinology and Metabolism. Jan, 2005 | Pubmed ID: 15507514 [Prostatic Cancer] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Nov, 2004 | Pubmed ID: 15779654 [Genito-scrotal Pathology in the Boy and in the Man] La Revue Du Praticien. Jun, 2004 | Pubmed ID: 15496035 [Endocrine Therapy for Localized or Locally Advanced Prostate Cancer] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Jun, 2004 | Pubmed ID: 15373195 [Contribution of Fluorescence Immunocytochemistry (uCyt+TM) in the Postoperative Surveillance of Bladder Cancer] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Jun, 2004 | Pubmed ID: 15373172 [Urinary Incontinence in the Adult. Diagnostic Management] La Revue Du Praticien. Apr, 2004 | Pubmed ID: 15253294 [Spermatocytic Seminoma. A Clinicopathological and Immunohistochemical Study of 7 Cases] Annales De Pathologie. Apr, 2004 | Pubmed ID: 15220835 [Biopsy Technique and Biopsy Schemes for a First Series of Prostatic Biopsies] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Apr, 2004 | Pubmed ID: 15217126 Characterization of Tumour Necrosis Factor-alpha-related Apoptosis-inducing Ligand and Its Receptors in the Adult Human Testis Molecular Human Reproduction. Feb, 2004 | Pubmed ID: 14742697 [Management in Case of Isolated Precancerous Lesions of the Prostate (HG-PIN) Discovered with Biopsy] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Nov, 2003 | Pubmed ID: 15816403 [Two Indications for Bilateral Neuromodulation] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Dec, 2003 | Pubmed ID: 15000321 [Hormonal Therapy in Metastatic Prostatic Cancer] Progrès En Urologie : Journal De L'Association Française D'urologie Et De La Société Française D'urologie. Apr, 2003 | Pubmed ID: 12765081 The Survival Effect of Prolactin on PC3 Prostate Cancer Cells European Urology. Mar, 2003 | Pubmed ID: 12600435 Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer Philippe Pérot1,2, Valérie Cheynet1,2, Myriam Decaussin-Petrucci1,3,4, Guy Oriol1,2, Nathalie Mugnier5, Claire Rodriguez-Lafrasse1,4,6, Alain Ruffion1,4,7, François Mallet1,2 1Joint Unit Hospices de Lyon-bioMérieux, 2Medical Diagnostic Discovery Department, BioMérieux, 3Department of Pathology and Cytology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 4Medical Faculty, Lyon 1 University, 5Data and Knowledge Laboratory, BioMérieux, 6Department of Biochemistry and Molecular Biology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 7Department of Urology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon JoVE 50713 Medicine
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer Philippe Pérot1,2, Valérie Cheynet1,2, Myriam Decaussin-Petrucci1,3,4, Guy Oriol1,2, Nathalie Mugnier5, Claire Rodriguez-Lafrasse1,4,6, Alain Ruffion1,4,7, François Mallet1,2 1Joint Unit Hospices de Lyon-bioMérieux, 2Medical Diagnostic Discovery Department, BioMérieux, 3Department of Pathology and Cytology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 4Medical Faculty, Lyon 1 University, 5Data and Knowledge Laboratory, BioMérieux, 6Department of Biochemistry and Molecular Biology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 7Department of Urology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon JoVE 50713 Medicine
