Articles by Alejandro Valencia-Tobón in JoVE

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

JoVE 3533 4/21/2012

Sara M. Robledo¹, Lina M. Carrillo^1,2, Alejandro Daza¹, Adriana M. Restrepo¹, Diana L. Muñoz¹, Jairo Tobón¹, Javier D. Murillo¹, Anderson López¹, Carolina Ríos¹, Carol V. Mesa¹, Yulieth A. Upegui¹, Alejandro Valencia-Tobón¹, Karina Mondragón-Shem¹, Berardo RodrÍguez², Iván D. Vélez¹

¹Program for the Study and Control of Tropical Diseases -PECET-School of Medicine, University of Antioquia, ²School of Agrarian Sciences, University of Antioquia

Optimization of the experimental hamster model for cutaneous leishmaniasis by intradermal injection of Leishmania promastigotes at the dorsal skin. This approach is useful during inoculation, follow-up, characterization of lesions, application of treatments and obtaining of clinical samples. Locomotion, search for food and water, play and social activities are preserved.