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The Journal of Visualized Experiments (JoVE) is a peer reviewed, PubMed-indexed video journal. Our mission is to increase the productivity of scientific research.

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Articles by Alisa B. Schiffman in JoVE

 JoVE General

Immunofluorescens Upptäckt av två tymidinanaloger (CldU och IDU) i Primär Tissue


JoVE 2166 12/07/2010

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Division of Endocrinology and Diabetes, Children’s Hospital of Philadelphia, Institute of Diabetes Obesity and Metabolism, Institute for Regenerative Medicine, Department of Pediatrics, University of Pennsylvania-School of Medicine

Vi har härledda en strategi för att upptäcka sekventiell inkorporering av tymidinanaloger (CldU och IDU) i vävnader hos vuxna möss att kvantifiera två på varandra följande rundorna av celldelning. Denna strategi är användbar för att identifiera celler omsättning långlivade vävnader, onkogena omvandling eller transitering-förstärkning celler.

Other articles by Alisa B. Schiffman on PubMed

Extremes of Clinical and Enzymatic Phenotypes in Children with Hyperinsulinism Caused by Glucokinase Activating Mutations

Diabetes. Jun, 2009  |  Pubmed ID: 19336674

Heterozygous activating mutations of glucokinase have been reported to cause hypoglycemia attributable to hyperinsulinism in a limited number of families. We report three children with de novo glucokinase hyperinsulinism mutations who displayed a spectrum of clinical phenotypes corresponding to marked differences in enzyme kinetics.

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