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Articles by Allan J. Guimarães in JoVE

 JoVE Immunology and Infection

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens


JoVE 2532 2/14/2011

Department of Microbiology and Immunology, Albert Einstein College of Medicine

C57BL/6 mice have been used to study Hc pathogenesis and provide the best model. We are exploring the potential benefits of humoral immunity against this fungus and generated several mAbs [to histone H2B and a heat shock protein 60kDa] that we tested for their protective efficacy after intraperitoneal administration.

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