Asma Nusrat Department of Pathology University of Michigan Biography Publications Institution JoVE Articles Asma Nusrat has not added a biography. If you are Asma Nusrat and would like to personalize this page please email our Author Liaison for assistance. Publications Dysregulation of Intestinal Epithelial CFTR-dependent Cl Ion Transport and Paracellular Barrier Function Drives Gastrointestinal Symptoms of Food-induced Anaphylaxis in Mice Mucosal Immunology. 01, 2021 | Pubmed ID: 32576925 IL-36R Signaling Integrates Innate and Adaptive Immune-mediated Protection Against Enteropathogenic Bacteria Proceedings of the National Academy of Sciences of the United States of America. 11, 2020 | Pubmed ID: 33087566 WD40 Repeat Protein 26 Negatively Regulates Formyl Peptide Receptor-1 Mediated Wound Healing in Intestinal Epithelial Cells The American Journal of Pathology. 10, 2020 | Pubmed ID: 32958140 The Intermucosal Connection Between the Mouth and Gut in Commensal Pathobiont-Driven Colitis Cell. Jul, 2020 | Pubmed ID: 32758418 Neutrophil Expressed CD47 Regulates CD11b/CD18-dependent Neutrophil Transepithelial Migration in the Intestine in Vivo Mucosal Immunology. Jun, 2020 | Pubmed ID: 32561828 Blocking Integrin αβ-mediated CD4 T Cell Recruitment to the Intestine and Liver Protects Mice from Western Diet-induced Non-alcoholic Steatohepatitis Journal of Hepatology. Nov, 2020 | Pubmed ID: 32540177 Western Diet-induced Increase in Colonic Bile Acids Compromises Epithelial Barrier in Nonalcoholic Steatohepatitis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 05, 2020 | Pubmed ID: 32275114 Desmocollin-2 Promotes Intestinal Mucosal Repair by Controlling Integrin-dependent Cell Adhesion and Migration Molecular Biology of the Cell. 03, 2020 | Pubmed ID: 31967937 Integrated Imaging Methodology Detects Claudin-1 Expression in Premalignant Nonpolypoid and Polypoid Colonic Epithelium in Mice Clinical and Translational Gastroenterology. 01, 2020 | Pubmed ID: 31922993 Regulation of Neutrophil Function by Selective Targeting of Glycan Epitopes Expressed on the Integrin CD11b/CD18 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 02, 2020 | Pubmed ID: 31907993 MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State Cell Reports. 11, 2019 | Pubmed ID: 31775036 Innate Immune Cell-epithelial Crosstalk During Wound Repair The Journal of Clinical Investigation. 07, 2019 | Pubmed ID: 31329162 Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8 T-Cell Activation Frontiers in Immunology. 2019 | Pubmed ID: 30936879 Interactions Between Commensal Bacteria and Enteric Neurons, Via FPR1 Induction of ROS, Increase Gastrointestinal Motility In Mice Gastroenterology. 07, 2019 | Pubmed ID: 30930024 Macrophage-dependent Neutrophil Recruitment is Impaired Under Conditions of Increased Intestinal Permeability in JAM-A-deficient Mice Mucosal Immunology. 05, 2019 | Pubmed ID: 30745566 Role of JAM-A Tyrosine Phosphorylation in Epithelial Barrier Dysfunction During Intestinal Inflammation Molecular Biology of the Cell. 03, 2019 | Pubmed ID: 30625033 Analysis of Leukocyte Transepithelial Migration Using an in Vivo Murine Colonic Loop Model JCI Insight. 10, 2018 | Pubmed ID: 30333307 Cadherins: Cellular Adhesive Molecules Serving As Signalling Mediators The Journal of Physiology. 09, 2018 | Pubmed ID: 29968384 A Cytokine Network Involving IL-36γ, IL-23, and IL-22 Promotes Antimicrobial Defense and Recovery from Intestinal Barrier Damage Proceedings of the National Academy of Sciences of the United States of America. 05, 2018 | Pubmed ID: 29760082 Serum Amyloid A1 Is an Epithelial Prorestitutive Factor The American Journal of Pathology. 04, 2018 | Pubmed ID: 29366677 Indian Hedgehog Suppresses Intestinal Inflammation Cellular and Molecular Gastroenterology and Hepatology. 2018 | Pubmed ID: 29276751 Synthetic Hydrogels for Human Intestinal Organoid Generation and Colonic Wound Repair Nature Cell Biology. Nov, 2017 | Pubmed ID: 29058719 IL-36γ Signaling Controls the Induced Regulatory T Cell-Th9 Cell Balance Via NFκB Activation and STAT Transcription Factors Mucosal Immunology. 11, 2017 | Pubmed ID: 28327619 IL-17A-mediated Neutrophil Recruitment Limits Expansion of Segmented Filamentous Bacteria Mucosal Immunology. 05, 2017 | Pubmed ID: 27624780 Cosmc is an X-linked Inflammatory Bowel Disease Risk Gene That Spatially Regulates Gut Microbiota and Contributes to Sex-specific Risk Proceedings of the National Academy of Sciences of the United States of America. 12, 2016 | Pubmed ID: 27930307 Overexpressed Claudin-1 Can Be Visualized Endoscopically In Colonic Adenomas In Vivo Cellular and Molecular Gastroenterology and Hepatology. Mar, 2016 | Pubmed ID: 27840845 Claudin-based Barrier Differentiation in the Colonic Epithelial Crypt Niche Involves Hopx/Klf4 and Tcf7l2/Hnf4-α Cascades Tissue Barriers. Jul-Sep, 2016 | Pubmed ID: 27583195 Deposition of Microparticles by Neutrophils Onto Inflamed Epithelium: a New Mechanism to Disrupt Epithelial Intercellular Adhesions and Promote Transepithelial Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 12, 2016 | Pubmed ID: 27553226 Pharmacological Targeting of the Inflamed Intestinal Barrier Current Pharmaceutical Design. 2016 | Pubmed ID: 27464718 Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair Gastroenterology. 10, 2016 | Pubmed ID: 27436072 Redox Control of Cas Phosphorylation Requires Abl Kinase in Regulation of Intestinal Epithelial Cell Spreading and Migration American Journal of Physiology. Gastrointestinal and Liver Physiology. Sep, 2016 | Pubmed ID: 27418680 Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol Gastroenterology. 10, 2016 | Pubmed ID: 27342212 Annexin A1: Shifting the Balance Towards Resolution and Repair Biological Chemistry. 10, 2016 | Pubmed ID: 27232634 Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage Journal of Immunology (Baltimore, Md. : 1950). Jan, 2016 | Pubmed ID: 26590314 Inflammation-induced Desmoglein-2 Ectodomain Shedding Compromises the Mucosal Barrier Molecular Biology of the Cell. Sep, 2015 | Pubmed ID: 26224314 HNF4α Regulates Claudin-7 Protein Expression During Intestinal Epithelial Differentiation The American Journal of Pathology. Aug, 2015 | Pubmed ID: 26216285 Claudin Switching: Physiological Plasticity of the Tight Junction Seminars in Cell & Developmental Biology. May, 2015 | Pubmed ID: 25957515 Introduction for the Special Issue on "Tissue Barriers in Inflammation" Tissue Barriers. 2015 | Pubmed ID: 25927017 Annexin A1-containing Extracellular Vesicles and Polymeric Nanoparticles Promote Epithelial Wound Repair The Journal of Clinical Investigation. Mar, 2015 | Pubmed ID: 25664854 Junctional Adhesion Molecule A Promotes Epithelial Tight Junction Assembly to Augment Lung Barrier Function The American Journal of Pathology. Feb, 2015 | Pubmed ID: 25438062 Human Neutrophil Formyl Peptide Receptor Phosphorylation and the Mucosal Inflammatory Response Journal of Leukocyte Biology. Jan, 2015 | Pubmed ID: 25395303 RhoGTPases, Actomyosin Signaling and Regulation of the Epithelial Apical Junctional Complex Seminars in Cell & Developmental Biology. Dec, 2014 | Pubmed ID: 25223584 Immunohistological Characterization of Intercellular Junction Proteins in Rhesus Macaque Intestine Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie. Dec, 2014 | Pubmed ID: 25153024 IFNγ-induced Suppression of β-catenin Signaling: Evidence for Roles of Akt and 14.3.3ζ Molecular Biology of the Cell. Oct, 2014 | Pubmed ID: 25079689 Periostin and Receptor Activator of Nuclear Factor κ-B Ligand Expression in Allergic Fungal Rhinosinusitis International Forum of Allergy & Rhinology. Sep, 2014 | Pubmed ID: 25060295 Proinflammatory Cytokine-induced Tight Junction Remodeling Through Dynamic Self-assembly of Claudins Molecular Biology of the Cell. Sep, 2014 | Pubmed ID: 25031428 Crohn's Disease-associated Escherichia Coli Survive in Macrophages by Suppressing NFκB Signaling Inflammatory Bowel Diseases. Aug, 2014 | Pubmed ID: 24918323 Trans-dimerization of JAM-A Regulates Rap2 and is Mediated by a Domain That is Distinct from the Cis-dimerization Interface Molecular Biology of the Cell. May, 2014 | Pubmed ID: 24672055 JAM-related Proteins in Mucosal Homeostasis and Inflammation Seminars in Immunopathology. Mar, 2014 | Pubmed ID: 24667924 Epithelial Adhesive Junctions F1000prime Reports. 2014 | Pubmed ID: 24592313 Galectin-3 Regulates Desmoglein-2 and Intestinal Epithelial Intercellular Adhesion The Journal of Biological Chemistry. Apr, 2014 | Pubmed ID: 24567334 Interleukin-4 and Interleukin-13 Compromise the Sinonasal Epithelial Barrier and Perturb Intercellular Junction Protein Expression International Forum of Allergy & Rhinology. May, 2014 | Pubmed ID: 24510479 Gut Commensal Bacteria and Regional Wnt Gene Expression in the Proximal Versus Distal Colon The American Journal of Pathology. Mar, 2014 | Pubmed ID: 24418259 Cleavage of Transmembrane Junction Proteins and Their Role in Regulating Epithelial Homeostasis Tissue Barriers. Apr, 2013 | Pubmed ID: 24665393 Tumor Necrosis Factor-neuropeptide Y Cross Talk Regulates Inflammation, Epithelial Barrier Functions, and Colonic Motility Inflammatory Bowel Diseases. Nov, 2013 | Pubmed ID: 24108115 α3/4 Fucosyltransferase 3-dependent Synthesis of Sialyl Lewis A on CD44 Variant Containing Exon 6 Mediates Polymorphonuclear Leukocyte Detachment from Intestinal Epithelium During Transepithelial Migration Journal of Immunology (Baltimore, Md. : 1950). Nov, 2013 | Pubmed ID: 24068663 JAM-A Associates with ZO-2, Afadin, and PDZ-GEF1 to Activate Rap2c and Regulate Epithelial Barrier Function Molecular Biology of the Cell. Sep, 2013 | Pubmed ID: 23885123 The N-BAR Domain Protein, Bin3, Regulates Rac1- and Cdc42-dependent Processes in Myogenesis Developmental Biology. Oct, 2013 | Pubmed ID: 23872330 House Dust Mite Allergen Der P 1 Effects on Sinonasal Epithelial Tight Junctions International Forum of Allergy & Rhinology. Aug, 2013 | Pubmed ID: 23592402 Annexin A2 Regulates β1 Integrin Internalization and Intestinal Epithelial Cell Migration The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23558678 Distinct Phospholipase C-β Isozymes Mediate Lysophosphatidic Acid Receptor 1 Effects on Intestinal Epithelial Homeostasis and Wound Closure Molecular and Cellular Biology. May, 2013 | Pubmed ID: 23478264 Sinonasal Epithelial Wound Resealing in an in Vitro Model: Inhibition of Wound Closure with IL-4 Exposure International Forum of Allergy & Rhinology. Jun, 2013 | Pubmed ID: 23468432 Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda Inflammatory Bowel Diseases. Mar, 2013 | Pubmed ID: 23448796 Activation of PKCβII by PMA Facilitates Enhanced Epithelial Wound Repair Through Increased Cell Spreading and Migration PloS One. 2013 | Pubmed ID: 23409039 Annexin A1, Formyl Peptide Receptor, and NOX1 Orchestrate Epithelial Repair The Journal of Clinical Investigation. Jan, 2013 | Pubmed ID: 23241962 Epithelial Permeability Alterations in an in Vitro Air-liquid Interface Model of Allergic Fungal Rhinosinusitis International Forum of Allergy & Rhinology. Jan, 2013 | Pubmed ID: 22927233 Compromised Intestinal Epithelial Barrier Induces Adaptive Immune Compensation That Protects from Colitis Immunity. Sep, 2012 | Pubmed ID: 22981539 Regulation of Epithelial Proliferation by Tight Junction Proteins Annals of the New York Academy of Sciences. Jul, 2012 | Pubmed ID: 22731724 Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function The American Journal of Pathology. Feb, 2012 | Pubmed ID: 22155109 The Life and Death of Epithelia During Inflammation: Lessons Learned from the Gut Annual Review of Pathology. 2012 | Pubmed ID: 21838548 Epithelial Tight Junction Alterations in Nasal Polyposis International Forum of Allergy & Rhinology. Jan-Feb, 2011 | Pubmed ID: 22287308 SOX4 Interacts with Plakoglobin in a Wnt3a-dependent Manner in Prostate Cancer Cells BMC Cell Biology. 2011 | Pubmed ID: 22098624 CX3CR1 Regulates Intestinal Macrophage Homeostasis, Bacterial Translocation, and Colitogenic Th17 Responses in Mice The Journal of Clinical Investigation. Dec, 2011 | Pubmed ID: 22045567 Enteric Commensal Bacteria Induce Extracellular Signal-regulated Kinase Pathway Signaling Via Formyl Peptide Receptor-dependent Redox Modulation of Dual Specific Phosphatase 3 The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21921027 Krüppel-like Factor 5 is Important for Maintenance of Crypt Architecture and Barrier Function in Mouse Intestine Gastroenterology. Oct, 2011 | Pubmed ID: 21763241 Characterization of Full-length and Proteolytic Cleavage Fragments of Desmoglein-2 in Native Human Colon and Colonic Epithelial Cell Lines Cell Adhesion & Migration. Jul-Aug, 2011 | Pubmed ID: 21715983 Enteric Commensal Bacteria Potentiate Epithelial Restitution Via Reactive Oxygen Species-mediated Inactivation of Focal Adhesion Kinase Phosphatases Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21555563 The Wnt Antagonist Dkk1 Regulates Intestinal Epithelial Homeostasis and Wound Repair Gastroenterology. Jul, 2011 | Pubmed ID: 21440550 Tight Function Zonula Occludens-3 Regulates Cyclin D1-dependent Cell Proliferation Molecular Biology of the Cell. May, 2011 | Pubmed ID: 21411630 JAM-A Regulates Epithelial Proliferation Through Akt/β-catenin Signalling EMBO Reports. Apr, 2011 | Pubmed ID: 21372850 Loss of Desmocollin-2 Confers a Tumorigenic Phenotype to Colonic Epithelial Cells Through Activation of Akt/β-catenin Signaling Molecular Biology of the Cell. Apr, 2011 | Pubmed ID: 21325624 Commensal-epithelial Signaling Mediated Via Formyl Peptide Receptors The American Journal of Pathology. Dec, 2010 | Pubmed ID: 21037077 Neutrophil Migration Across Intestinal Epithelium: Evidence for a Role of CD44 in Regulating Detachment of Migrating Cells from the Luminal Surface Journal of Immunology (Baltimore, Md. : 1950). Dec, 2010 | Pubmed ID: 20974992 Glycogen Synthase Kinase 3 (GSK-3) Influences Epithelial Barrier Function by Regulating Occludin, Claudin-1 and E-cadherin Expression Biochemical and Biophysical Research Communications. Jul, 2010 | Pubmed ID: 20617560 Cytoskeletal Regulation of Epithelial Barrier Function During Inflammation The American Journal of Pathology. Aug, 2010 | Pubmed ID: 20581053 Interferon-gamma Regulates Intestinal Epithelial Homeostasis Through Converging Beta-catenin Signaling Pathways Immunity. Mar, 2010 | Pubmed ID: 20303298 Epithelial NF-kappaB Enhances Transmucosal Fluid Movement by Altering Tight Junction Protein Composition After T Cell Activation The American Journal of Pathology. Jan, 2010 | Pubmed ID: 20008138 Tumor Suppressor Scribble Regulates Assembly of Tight Junctions in the Intestinal Epithelium The American Journal of Pathology. Jan, 2010 | Pubmed ID: 19959811 Coronin 1C Negatively Regulates Cell-matrix Adhesion and Motility of Intestinal Epithelial Cells Biochemical and Biophysical Research Communications. Jan, 2010 | Pubmed ID: 19913511 Dkk-1 Inhibits Intestinal Epithelial Cell Migration by Attenuating Directional Polarization of Leading Edge Cells Molecular Biology of the Cell. Nov, 2009 | Pubmed ID: 19776352 Dynamic Regulation of Epithelial Cell Fate and Barrier Function by Intercellular Junctions Annals of the New York Academy of Sciences. May, 2009 | Pubmed ID: 19538310 Protein Kinase C Activation Disrupts Epithelial Apical Junctions Via ROCK-II Dependent Stimulation of Actomyosin Contractility BMC Cell Biology. 2009 | Pubmed ID: 19422706 The Bacterial Virulence Factor Lymphostatin Compromises Intestinal Epithelial Barrier Function by Modulating Rho GTPases The American Journal of Pathology. Apr, 2009 | Pubmed ID: 19286565 Regulation of Epithelial Apical Junctional Complex by Rho Family GTPases Frontiers in Bioscience (Landmark Edition). 2009 | Pubmed ID: 19273120 Junctional Adhesion Molecule A Interacts with Afadin and PDZ-GEF2 to Activate Rap1A, Regulate Beta1 Integrin Levels, and Enhance Cell Migration Molecular Biology of the Cell. Apr, 2009 | Pubmed ID: 19176753 Non-muscle Myosin IIA Differentially Regulates Intestinal Epithelial Cell Restitution and Matrix Invasion The American Journal of Pathology. Feb, 2009 | Pubmed ID: 19147824 Flotillin-1 Stabilizes Caveolin-1 in Intestinal Epithelial Cells Biochemical and Biophysical Research Communications. Feb, 2009 | Pubmed ID: 19121286 Cytokine Regulation of Tight Junctions Biochimica Et Biophysica Acta. Apr, 2009 | Pubmed ID: 18952050 Pathophysiology of Nasal Polyposis: the Role of Desmosomal Junctions American Journal of Rhinology. Nov-Dec, 2008 | Pubmed ID: 19178795 Neutrophil-mediated Activation of Epithelial Protease-activated Receptors-1 and -2 Regulates Barrier Function and Transepithelial Migration Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18832729 Annexin A1 Regulates Intestinal Mucosal Injury, Inflammation, and Repair Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18802107 Lipid Rafts Mediate Internalization of Beta1-integrin in Migrating Intestinal Epithelial Cells American Journal of Physiology. Gastrointestinal and Liver Physiology. Nov, 2008 | Pubmed ID: 18755811 Myosin II Regulates the Shape of Three-dimensional Intestinal Epithelial Cysts Journal of Cell Science. Jun, 2008 | Pubmed ID: 18460584 Vesicular Trafficking: Molecular Tools and Targets Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18369933 A Key Claudin Extracellular Loop Domain is Critical for Epithelial Barrier Integrity The American Journal of Pathology. Apr, 2008 | Pubmed ID: 18349130 Cis-dimerization Mediates Function of Junctional Adhesion Molecule A Molecular Biology of the Cell. May, 2008 | Pubmed ID: 18272784 Role of the Intestinal Barrier in Inflammatory Bowel Disease World Journal of Gastroenterology : WJG. Jan, 2008 | Pubmed ID: 18200662 Formyl Peptide Receptor-1 Activation Enhances Intestinal Epithelial Cell Restitution Through Phosphatidylinositol 3-kinase-dependent Activation of Rac1 and Cdc42 Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056353 JAM-A Regulates Permeability and Inflammation in the Intestine in Vivo The Journal of Experimental Medicine. Dec, 2007 | Pubmed ID: 18039951 Desmoglein-2: a Novel Regulator of Apoptosis in the Intestinal Epithelium Molecular Biology of the Cell. Nov, 2007 | Pubmed ID: 17804817 A Unique Role for Nonmuscle Myosin Heavy Chain IIA in Regulation of Epithelial Apical Junctions PloS One. 2007 | Pubmed ID: 17668046 Invasive Escherichia Coli Are a Feature of Crohn's Disease Laboratory Investigation; a Journal of Technical Methods and Pathology. Oct, 2007 | Pubmed ID: 17660846 Rho/Rho-associated Kinase-II Signaling Mediates Disassembly of Epithelial Apical Junctions Molecular Biology of the Cell. Sep, 2007 | Pubmed ID: 17596509 Annexin 2 Regulates Intestinal Epithelial Cell Spreading and Wound Closure Through Rho-related Signaling The American Journal of Pathology. Mar, 2007 | Pubmed ID: 17322380 Organized Migration of Epithelial Cells Requires Control of Adhesion and Protrusion Through Rho Kinase Effectors American Journal of Physiology. Gastrointestinal and Liver Physiology. Mar, 2007 | Pubmed ID: 17138966 Inflammatory Bowel Disease and the Apical Junctional Complex Annals of the New York Academy of Sciences. Aug, 2006 | Pubmed ID: 17057204 Tight Junctions and Cell-cell Interactions Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16799199 Annexin I Regulates SKCO-15 Cell Invasion by Signaling Through Formyl Peptide Receptors The Journal of Biological Chemistry. Jul, 2006 | Pubmed ID: 16675446 Plasmid DNA and SiRNA Transfection of Intestinal Epithelial Monolayers by Electroporation International Journal of Pharmaceutics. Jun, 2006 | Pubmed ID: 16564652 Microtubules Regulate Disassembly of Epithelial Apical Junctions BMC Cell Biology. 2006 | Pubmed ID: 16509970 Regulation of the Intestinal Epithelial Barrier by the Apical Junctional Complex Current Opinion in Gastroenterology. Mar, 2006 | Pubmed ID: 16462161 Interferon-gamma Inhibits T84 Epithelial Cell Migration by Redirecting Transcytosis of Beta1 Integrin from the Migrating Leading Edge Journal of Immunology (Baltimore, Md. : 1950). Sep, 2005 | Pubmed ID: 16148152 Mechanism of IFN-gamma-induced Endocytosis of Tight Junction Proteins: Myosin II-dependent Vacuolarization of the Apical Plasma Membrane Molecular Biology of the Cell. Oct, 2005 | Pubmed ID: 16055505 Interferon-gamma Induces Internalization of Epithelial Tight Junction Proteins Via a Macropinocytosis-like Process FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2005 | Pubmed ID: 15923402 The Second Loop of Occludin is Required for Suppression of Raf1-induced Tumor Growth Oncogene. Jun, 2005 | Pubmed ID: 15806147 Neutrophil Migration Across Tight Junctions is Mediated by Adhesive Interactions Between Epithelial Coxsackie and Adenovirus Receptor and a Junctional Adhesion Molecule-like Protein on Neutrophils Molecular Biology of the Cell. Jun, 2005 | Pubmed ID: 15800062 Differential Roles for Actin Polymerization and a Myosin II Motor in Assembly of the Epithelial Apical Junctional Complex Molecular Biology of the Cell. Jun, 2005 | Pubmed ID: 15800060 Endocytosis of the Apical Junctional Complex: Mechanisms and Possible Roles in Regulation of Epithelial Barriers BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Apr, 2005 | Pubmed ID: 15770686 Citrobacter Rodentium LifA/efa1 is Essential for Colonic Colonization and Crypt Cell Hyperplasia in Vivo Infection and Immunity. Mar, 2005 | Pubmed ID: 15731042 Junctional Adhesion Molecule 1 Regulates Epithelial Cell Morphology Through Effects on Beta1 Integrins and Rap1 Activity The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15677455 Multiple Protein Interactions Involving Proposed Extracellular Loop Domains of the Tight Junction Protein Occludin Molecular Biology of the Cell. Apr, 2005 | Pubmed ID: 15659655 The Epithelium in Inflammatory Bowel Disease: Potential Role of Endocytosis of Junctional Proteins in Barrier Disruption Novartis Foundation Symposium. 2004 | Pubmed ID: 15669638 Coordinated Redistribution of Leukocyte LFA-1 and Endothelial Cell ICAM-1 Accompany Neutrophil Transmigration The Journal of Experimental Medicine. Dec, 2004 | Pubmed ID: 15611287 Association of BAP31 with CD11b/CD18. Potential Role in Intracellular Trafficking of CD11b/CD18 in Neutrophils The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15294914 JAM-C is a Component of Desmosomes and a Ligand for CD11b/CD18-mediated Neutrophil Transepithelial Migration Molecular Biology of the Cell. Aug, 2004 | Pubmed ID: 15194813 Epithelial Cell Spreading Induced by Hepatocyte Growth Factor Influences Paxillin Protein Synthesis and Posttranslational Modification American Journal of Physiology. Gastrointestinal and Liver Physiology. Oct, 2004 | Pubmed ID: 15191880 ICAM-1: Targeted Docking for Exogenous As Well As Endogenous Ligands Advanced Drug Delivery Reviews. Apr, 2004 | Pubmed ID: 15063588 Role for Actin Filament Turnover and a Myosin II Motor in Cytoskeleton-driven Disassembly of the Epithelial Apical Junctional Complex Molecular Biology of the Cell. Jun, 2004 | Pubmed ID: 15047870 RhoA, Rac1, and Cdc42 Exert Distinct Effects on Epithelial Barrier Via Selective Structural and Biochemical Modulation of Junctional Proteins and F-actin American Journal of Physiology. Cell Physiology. Aug, 2004 | Pubmed ID: 15044152 Aberrant Expression of Tight Junction-related Proteins ZO-1, Claudin-1 and Occludin in Synovial Sarcoma: an Immunohistochemical Study with Ultrastructural Correlation Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Feb, 2004 | Pubmed ID: 14704716 Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment Molecular Biology of the Cell. Jan, 2004 | Pubmed ID: 14528017 Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-independent Mechanisms Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003 | Pubmed ID: 14634132 Zonula Occludens-1 and Her-2/neu Expression in Invasive Breast Carcinoma Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Jun, 2003 | Pubmed ID: 12777995 Constitutive Activation of Rho Proteins by CNF-1 Influences Tight Junction Structure and Epithelial Barrier Function Journal of Cell Science. Feb, 2003 | Pubmed ID: 12538773 Expression of Claudin-1, a Recently Described Tight Junction-associated Protein, Distinguishes Soft Tissue Perineurioma from Potential Mimics The American Journal of Surgical Pathology. Dec, 2002 | Pubmed ID: 12459629 The Role of Endothelial Cell Lateral Junctions During Leukocyte Trafficking Immunological Reviews. Aug, 2002 | Pubmed ID: 12234362 Neutrophil Transepithelial Migration: Evidence for Sequential, Contact-dependent Signaling Events and Enhanced Paracellular Permeability Independent of Transjunctional Migration Journal of Immunology (Baltimore, Md. : 1950). Jul, 2002 | Pubmed ID: 12077279 Leukocyte Transendothelial Migration: a Junctional Affair Seminars in Immunology. Apr, 2002 | Pubmed ID: 11978082 Targeting Epithelial Expressed Sialyl Lewis Glycans Improves Colonic Mucosal Wound Healing and Protects Against Colitis JCI Insight. | Pubmed ID: 32427587 Resolvin E1 is a Pro-repair Molecule That Promotes Intestinal Epithelial Wound Healing Proceedings of the National Academy of Sciences of the United States of America. | Pubmed ID: 32300016 Erythroid Differentiation Regulator-1 Induced by Microbiota in Early Life Drives Intestinal Stem Cell Proliferation and Regeneration Nature Communications. | Pubmed ID: 31980634 Epithelial CD47 is Critical for Mucosal Repair in the Murine Intestine in Vivo Nature Communications. | Pubmed ID: 31676794 Formyl Peptide Receptor 2 Regulates Monocyte Recruitment to Promote Intestinal Mucosal Wound Repair FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. | Pubmed ID: 31585047 IFN-γ-tethered Hydrogels Enhance Mesenchymal Stem Cell-based Immunomodulation and Promote Tissue Repair Biomaterials. | Pubmed ID: 31401468 TNFα Promotes Mucosal Wound Repair Through Enhanced Platelet Activating Factor Receptor Signaling in the Epithelium Mucosal Immunology. | Pubmed ID: 30971752 IL-10 Produced by Macrophages Regulates Epithelial Integrity in the Small Intestine Scientific Reports. | Pubmed ID: 30718924 Saving Problematic Mucosae: SPMs in Intestinal Mucosal Inflammation and Repair Trends in Molecular Medicine. | Pubmed ID: 30642681 Publisher Correction: PEG-4MAL Hydrogels for Human Organoid Generation, Culture, and in Vivo Delivery Nature Protocols. | Pubmed ID: 30356140 Contribution of Wound-Associated Cells and Mediators in Orchestrating Gastrointestinal Mucosal Wound Repair Annual Review of Physiology. | Pubmed ID: 30354933 PEG-4MAL Hydrogels for Human Organoid Generation, Culture, and in Vivo Delivery Nature Protocols. | Pubmed ID: 30190557 Intracellular Desmoglein-2 Cleavage Sensitizes Epithelial Cells to Apoptosis in Response to Pro-inflammatory Cytokines Cell Death & Disease. | Pubmed ID: 29523777 Macrophage-derived IL-10 Mediates Mucosal Repair by Epithelial WISP-1 Signaling The Journal of Clinical Investigation. | Pubmed ID: 28783045 Intestinal Epithelial Claudins: Expression and Regulation in Homeostasis and Inflammation Annals of the New York Academy of Sciences. | Pubmed ID: 28493289 The Microenvironment of Injured Murine Gut Elicits a Local Pro-restitutive Microbiota Nature Microbiology. | Pubmed ID: 27571978 Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model Vicky Garcia-Hernandez1, Philipp-Alexander Neumann2, Stefan Koch3,4, Renae Lyons1, Asma Nusrat1, Charles A. Parkos1 1Department of Pathology, University of Michigan, 2Department of Surgery, Klinikum Rechts der Isar, Technische Universität München, 3Wallenberg Centre for Molecular Medicine, Linköping University, 4Department of Biomedical and Clinical Sciences (BKV), Linköping University JoVE 62135 Immunology and Infection Generation of Murine Primary Colon Epithelial Monolayers from Intestinal Crypts Chithra K Muraleedharan1, Jay Mierzwiak1, Darius Feier1, Asma Nusrat1, Miguel Quiros1 1Department of Pathology, School of Medicine, University of Michigan JoVE 62156 Biology Cryosectioning Method for Microdissection of Murine Colonic Mucosa Attila E. Farkas1, Christian Gerner-Smidt1, Loukia Lili1, Asma Nusrat1, Christopher T. Capaldo1 1Epithelial Pathobiology and Mucosal Inflammation Research Unit, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia JoVE 53112 Biology
Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model Vicky Garcia-Hernandez1, Philipp-Alexander Neumann2, Stefan Koch3,4, Renae Lyons1, Asma Nusrat1, Charles A. Parkos1 1Department of Pathology, University of Michigan, 2Department of Surgery, Klinikum Rechts der Isar, Technische Universität München, 3Wallenberg Centre for Molecular Medicine, Linköping University, 4Department of Biomedical and Clinical Sciences (BKV), Linköping University JoVE 62135 Immunology and Infection
Generation of Murine Primary Colon Epithelial Monolayers from Intestinal Crypts Chithra K Muraleedharan1, Jay Mierzwiak1, Darius Feier1, Asma Nusrat1, Miguel Quiros1 1Department of Pathology, School of Medicine, University of Michigan JoVE 62156 Biology
Cryosectioning Method for Microdissection of Murine Colonic Mucosa Attila E. Farkas1, Christian Gerner-Smidt1, Loukia Lili1, Asma Nusrat1, Christopher T. Capaldo1 1Epithelial Pathobiology and Mucosal Inflammation Research Unit, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia JoVE 53112 Biology
