Carlos Cordon-Cardo Department of Pathology Icahn School of Medicine at Mount Sinai Biography Publications Institution JoVE Articles Carlos Cordon-Cardo has not added a biography. If you are Carlos Cordon-Cardo and would like to personalize this page please email our Author Liaison for assistance. Publications Myocardial Amyloid Quantification with Look-Locker Magnetic Resonance Sequence in Cardiac Amyloidosis. Diagnostic Accuracy in Clinical Practice and Histological Validation Journal of Cardiac Failure. Aug, 2017 | Pubmed ID: 28801077 Erratum: The Metabolic Co-regulator PGC1α Suppresses Prostate Cancer Metastasis Nature Cell Biology. Jun, 2017 | Pubmed ID: 28659639 MTORC1-dependent AMD1 Regulation Sustains Polyamine Metabolism in Prostate Cancer Nature. Jul, 2017 | Pubmed ID: 28658205 PTEN Counteracts FBXL2 to Promote IP3R3- and Ca(2+)-mediated Apoptosis Limiting Tumour Growth Nature. Jun, 2017 | Pubmed ID: 28614300 Targeting Sarcoma Tumor-initiating Cells Through Differentiation Therapy Stem Cell Research. May, 2017 | Pubmed ID: 28433655 MiR-424(322)/503 is a Breast Cancer Tumor Suppressor Whose Loss Promotes Resistance to Chemotherapy Genes & Development. Mar, 2017 | Pubmed ID: 28404630 The Nuclear Transport Receptor Importin-11 is a Tumor Suppressor That Maintains PTEN Protein The Journal of Cell Biology. Mar, 2017 | Pubmed ID: 28193700 Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes Molecular Diagnosis & Therapy. Apr, 2017 | Pubmed ID: 28000172 Reappraising Hyalinizing Clear Cell Carcinoma: A Population-based Study with Molecular Confirmation Head & Neck. Mar, 2017 | Pubmed ID: 27898192 The Role of GATA2 in Lethal Prostate Cancer Aggressiveness Nature Reviews. Urology. Jan, 2017 | Pubmed ID: 27872477 Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis Via Androgen Receptor Signaling The American Journal of Pathology. Dec, 2016 | Pubmed ID: 27770613 Protein Profiling of Bladder Urothelial Cell Carcinoma PloS One. 2016 | Pubmed ID: 27626805 The Metabolic Co-regulator PGC1α Suppresses Prostate Cancer Metastasis Nature Cell Biology. 06, 2016 | Pubmed ID: 27214280 Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition European Urology. Nov, 2016 | Pubmed ID: 27178450 Enrichment of Cells with Cancer Stem Cell-Like Markers in Relapses of Chemoresistant Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma Oncology. 2016 | Pubmed ID: 27077749 Immunopathologic Assessment of PTEN Expression Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27033068 H-RAS Mutation is a Key Molecular Feature of Pediatric Urothelial Bladder Cancer. A Detailed Report of Three Cases Journal of Pediatric Urology. Apr, 2016 | Pubmed ID: 26522772 Metabolic Reprogramming Induces Resistance to Anti-NOTCH1 Therapies in T Cell Acute Lymphoblastic Leukemia Nature Medicine. Oct, 2015 | Pubmed ID: 26390244 Expression of the Cancer Testis Antigen IGF2BP3 in Colorectal Cancers; IGF2BP3 Holds Promise As a Specific Immunotherapy Target Oncoscience. 2015 | Pubmed ID: 26244168 Inhibition of the Autocrine IL-6-JAK2-STAT3-calprotectin Axis As Targeted Therapy for HR-/HER2+ Breast Cancers Genes & Development. Aug, 2015 | Pubmed ID: 26227964 PI3K/AKT Pathway Regulates E-cadherin and Desmoglein 2 in Aggressive Prostate Cancer Cancer Medicine. Aug, 2015 | Pubmed ID: 26033689 MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis Due to IL6 Secretion and AKT Suppression Via PHLPP2 Cancer Discovery. Jun, 2015 | Pubmed ID: 25829425 Methodological Aspects of the Molecular and Histological Study of Prostate Cancer: Focus on PTEN Methods (San Diego, Calif.). May, 2015 | Pubmed ID: 25697760 A Targetable GATA2-IGF2 Axis Confers Aggressiveness in Lethal Prostate Cancer Cancer Cell. Feb, 2015 | Pubmed ID: 25670080 Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis Cancer Discovery. May, 2015 | Pubmed ID: 25653093 A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells Cancer Discovery. Apr, 2015 | Pubmed ID: 25614485 Massive Parallel Sequencing Uncovers Actionable FGFR2-PPHLN1 Fusion and ARAF Mutations in Intrahepatic Cholangiocarcinoma Nature Communications. 2015 | Pubmed ID: 25608663 Limited MiR-17-92 Overexpression Drives Hematologic Malignancies Leukemia Research. Mar, 2015 | Pubmed ID: 25597017 Loss of Sirt1 Promotes Prostatic Intraepithelial Neoplasia, Reduces Mitophagy, and Delays PARK2 Translocation to Mitochondria The American Journal of Pathology. Jan, 2015 | Pubmed ID: 25529796 ΔNp63 Expression is a Protective Factor of Progression in Clinical High Grade T1 Bladder Cancer The Journal of Urology. Apr, 2015 | Pubmed ID: 25444981 Biomarkers for Bladder Cancer Management: Present and Future American Journal of Clinical and Experimental Urology. 2014 | Pubmed ID: 25374904 Overcoming Tumor Heterogeneity in the Molecular Diagnosis of Urological Cancers Expert Review of Molecular Diagnostics. Nov, 2014 | Pubmed ID: 25327491 The MicroRNA 424/503 Cluster Reduces CDC25A Expression During Cell Cycle Arrest Imposed by Transforming Growth Factor β in Mammary Epithelial Cells Molecular and Cellular Biology. Dec, 2014 | Pubmed ID: 25266660 Bladder Cancers Arise from Distinct Urothelial Sub-populations Nature Cell Biology. Oct, 2014 | Pubmed ID: 25218638 A NOTCH1-driven MYC Enhancer Promotes T Cell Development, Transformation and Acute Lymphoblastic Leukemia Nature Medicine. Oct, 2014 | Pubmed ID: 25194570 Characterization of Desmoglein Expression in the Normal Prostatic Gland. Desmoglein 2 is an Independent Prognostic Factor for Aggressive Prostate Cancer PloS One. 2014 | Pubmed ID: 24896103 FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm Journal of the National Cancer Institute. Jun, 2014 | Pubmed ID: 24838835 Defining the Role of CD2 in Disease Progression and Overall Survival Among Patients with Completely Resected Stage-II to -III Cutaneous Melanoma Journal of the American Academy of Dermatology. Jun, 2014 | Pubmed ID: 24698703 The MiR-424(322)/503 Cluster Orchestrates Remodeling of the Epithelium in the Involuting Mammary Gland Genes & Development. Apr, 2014 | Pubmed ID: 24636986 Genomic Analysis in Active Surveillance: Predicting High-risk Disease Using Tissue Biomarkers Current Opinion in Urology. May, 2014 | Pubmed ID: 24625431 RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc As a Driver of Pten-Mutant Metastasis Cancer Discovery. Mar, 2014 | Pubmed ID: 24444712 Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia Cancer Cell. Dec, 2013 | Pubmed ID: 24291004 Zbtb7a Suppresses Prostate Cancer Through Repression of a Sox9-dependent Pathway for Cellular Senescence Bypass and Tumor Invasion Nature Genetics. Jul, 2013 | Pubmed ID: 23727861 A Co-clinical Approach Identifies Mechanisms and Potential Therapies for Androgen Deprivation Resistance in Prostate Cancer Nature Genetics. Jul, 2013 | Pubmed ID: 23727860 Dual Pten/Tp53 Suppression Promotes Sarcoma Progression by Activating Notch Signaling The American Journal of Pathology. Jun, 2013 | Pubmed ID: 23708211 Loss of PML Cooperates with Mutant P53 to Drive More Aggressive Cancers in a Gender-dependent Manner Cell Cycle (Georgetown, Tex.). Jun, 2013 | Pubmed ID: 23656786 Predicting High-risk Disease Using Tissue Biomarkers Current Opinion in Urology. May, 2013 | Pubmed ID: 23478499 A Common MicroRNA Signature Consisting of MiR-133a, MiR-139-3p, and MiR-142-3p Clusters Bladder Carcinoma in Situ with Normal Umbrella Cells The American Journal of Pathology. Apr, 2013 | Pubmed ID: 23410519 Compound In Vivo Inactivation of Pml and P53 Uncovers a Functional Interaction in Angiosarcoma Suppression Genes & Cancer. Sep, 2012 | Pubmed ID: 23486996 MAGE-A3 is Highly Expressed in a Subset of Colorectal Cancer Patients Cancer Immunity. 2012 | Pubmed ID: 23390371 Suppression of Acquired Docetaxel Resistance in Prostate Cancer Through Depletion of Notch- and Hedgehog-dependent Tumor-initiating Cells Cancer Cell. Sep, 2012 | Pubmed ID: 22975379 Targeting Nonclassical Oncogenes for Therapy in T-ALL Cancer Cell. Apr, 2012 | Pubmed ID: 22516257 Preclinical Analysis of the γ-secretase Inhibitor PF-03084014 in Combination with Glucocorticoids in T-cell Acute Lymphoblastic Leukemia Molecular Cancer Therapeutics. Jul, 2012 | Pubmed ID: 22504949 A BAC-based Transgenic Mouse Specifically Expresses an Inducible Cre in the Urothelium PloS One. 2012 | Pubmed ID: 22496911 Translocation Renal Cell Carcinomas in Adults: a Single-institution Experience The American Journal of Surgical Pathology. May, 2012 | Pubmed ID: 22446944 Perioperative Polyphenon E, a Green Tea Extract, Does Not Affect the Wound Complication Rate in Mice After Sham Laparotomy Yet Has an Inhibitory Effect on Wound Healing Surgical Innovation. Dec, 2012 | Pubmed ID: 22431911 MiR-143, MiR-222, and MiR-452 Are Useful As Tumor Stratification and Noninvasive Diagnostic Biomarkers for Bladder Cancer The American Journal of Pathology. May, 2012 | Pubmed ID: 22426337 PAX7-FKHR Fusion Gene Inhibits Myogenic Differentiation Via NF-kappaB Upregulation Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Mar, 2012 | Pubmed ID: 22374423 PPARγ Agonists Enhance ET-743-induced Adipogenic Differentiation in a Transgenic Mouse Model of Myxoid Round Cell Liposarcoma The Journal of Clinical Investigation. Mar, 2012 | Pubmed ID: 22293175 Postoperative Systems Models More Accurately Predict Risk of Significant Disease Progression Than Standard Risk Groups and a 10-year Postoperative Nomogram: Potential Impact on the Receipt of Adjuvant Therapy After Surgery BJU International. Jan, 2012 | Pubmed ID: 21771247 A Systems-based Modelling Approach Using Transurethral Resection of the Prostate (TURP) Specimens Yielded Incremental Prognostic Significance to Gleason when Predicting Long-term Outcome in Men with Localized Prostate Cancer BJU International. Jan, 2012 | Pubmed ID: 21733075 A Comparison of the Outcomes of Neoadjuvant and Adjuvant Chemotherapy for Clinical T2-T4aN0-N2M0 Bladder Cancer Cancer. Jan, 2012 | Pubmed ID: 21717438 CpG ODN, Toll Like Receptor (TLR)-9 Agonist, Inhibits Metastatic Colon Adenocarcinoma in a Murine Hepatic Tumor Model The Journal of Surgical Research. May, 2012 | Pubmed ID: 21324492 Personalized Approach to Prostate Cancer Prognosis Archivos Españoles De Urología. Oct, 2011 | Pubmed ID: 22052759 Anatomical Features of the Urethra and Urinary Bladder Catheterization in Female Mice and Rats. An Essential Translational Tool Acta Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia. 2011 | Pubmed ID: 22030824 Predictive Value of Microtubule Associated Proteins Tau and Stathmin in Patients with Nonmuscle Invasive Bladder Cancer Receiving Adjuvant Intravesical Taxane Therapy The Journal of Urology. Nov, 2011 | Pubmed ID: 21944130 Identification of PHLPP1 As a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-mutant Prostate Cancer Progression Cancer Cell. Aug, 2011 | Pubmed ID: 21840483 A Role for PML in Innate Immunity Genes & Cancer. Jan, 2011 | Pubmed ID: 21779477 KISS1 Methylation and Expression As Tumor Stratification Biomarkers and Clinical Outcome Prognosticators for Bladder Cancer Patients The American Journal of Pathology. Aug, 2011 | Pubmed ID: 21683672 Alternate PAX3 and PAX7 C-terminal Isoforms in Myogenic Differentiation and Sarcomagenesis Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Mar, 2011 | Pubmed ID: 21421465 Distinct Expression Profiles of P63 Variants During Urothelial Development and Bladder Cancer Progression The American Journal of Pathology. Mar, 2011 | Pubmed ID: 21356385 Three-dimensional Culture of Mouse Renal Carcinoma Cells in Agarose Macrobeads Selects for a Subpopulation of Cells with Cancer Stem Cell or Cancer Progenitor Properties Cancer Research. Feb, 2011 | Pubmed ID: 21266363 Hydrophilic Agarose Macrobead Cultures Select for Outgrowth of Carcinoma Cell Populations That Can Restrict Tumor Growth Cancer Research. Feb, 2011 | Pubmed ID: 21266362 Disruption of a Sirt1-dependent Autophagy Checkpoint in the Prostate Results in Prostatic Intraepithelial Neoplasia Lesion Formation Cancer Research. Feb, 2011 | Pubmed ID: 21189328 Mouse Models of Human Bladder Cancer As a Tool for Drug Discovery Current Protocols in Pharmacology / Editorial Board, S.J. Enna (editor-in-chief) ... [et Al.]. Jun, 2010 | Pubmed ID: 22294368 The TLX1 Oncogene Drives Aneuploidy in T Cell Transformation Nature Medicine. Nov, 2010 | Pubmed ID: 20972433 Association of Nuclear Localization of a Long Interspersed Nuclear Element-1 Protein in Breast Tumors with Poor Prognostic Outcomes Genes & Cancer. Feb, 2010 | Pubmed ID: 20948976 Impact of Stromal Sensitivity on Radiation Response of Tumors Implanted in SCID Hosts Revisited Cancer Research. Oct, 2010 | Pubmed ID: 20924105 Molecular Pathways of Urothelial Development and Bladder Tumorigenesis Urologic Oncology. Jul-Aug, 2010 | Pubmed ID: 20610278 Integrative Genome Comparison of Primary and Metastatic Melanomas PloS One. 2010 | Pubmed ID: 20520718 Associations Between NBS1 Polymorphisms, Haplotypes and Smoking-related Cancers Carcinogenesis. Jul, 2010 | Pubmed ID: 20478923 Galectin-3 Expression is Associated with Bladder Cancer Progression and Clinical Outcome Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Aug, 2010 | Pubmed ID: 20401558 Skp2 Targeting Suppresses Tumorigenesis by Arf-p53-independent Cellular Senescence Nature. Mar, 2010 | Pubmed ID: 20237562 PHF6 Mutations in T-cell Acute Lymphoblastic Leukemia Nature Genetics. Apr, 2010 | Pubmed ID: 20228800 Single Nucleotide Polymorphisms of 8 Inflammation-related Genes and Their Associations with Smoking-related Cancers International Journal of Cancer. Journal International Du Cancer. Nov, 2010 | Pubmed ID: 20112337 Overexpression of Phospho-eIF4E is Associated with Survival Through AKT Pathway in Non-small Cell Lung Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2010 | Pubmed ID: 20008839 Androgen Receptor Expression is Associated with Prostate Cancer-specific Survival in Castrate Patients with Metastatic Disease BJU International. Feb, 2010 | Pubmed ID: 19624594 MiR-19 is a Key Oncogenic Component of Mir-17-92 Genes & Development. Dec, 2009 | Pubmed ID: 20008935 Intravesical Delivery of Rapamycin Suppresses Tumorigenesis in a Mouse Model of Progressive Bladder Cancer Cancer Prevention Research (Philadelphia, Pa.). Dec, 2009 | Pubmed ID: 19952358 The N-Myc-DLL3 Cascade is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain Developmental Cell. Aug, 2009 | Pubmed ID: 19686682 MFH Classification: Differentiating Undifferentiated Pleomorphic Sarcoma in the 21st Century Expert Review of Anticancer Therapy. Aug, 2009 | Pubmed ID: 19671033 3-Phosphoinositide-dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-kinase Pathway in Breast Carcinoma Cancer Research. Aug, 2009 | Pubmed ID: 19602588 Systems Pathology: a Paradigm Shift in the Practice of Diagnostic and Predictive Pathology Cancer. Jul, 2009 | Pubmed ID: 19544549 Cyfip1 is a Putative Invasion Suppressor in Epithelial Cancers Cell. Jun, 2009 | Pubmed ID: 19524508 Personalized Prediction of Tumor Response and Cancer Progression on Prostate Needle Biopsy The Journal of Urology. Jul, 2009 | Pubmed ID: 19450827 Prediction of Prostate Cancer Recurrence Using Magnetic Resonance Imaging and Molecular Profiles Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009 | Pubmed ID: 19435838 Aberrant ERG Expression Cooperates with Loss of PTEN to Promote Cancer Progression in the Prostate Nature Genetics. May, 2009 | Pubmed ID: 19396168 A Systems Pathology Model for Predicting Overall Survival in Patients with Refractory, Advanced Non-small-cell Lung Cancer Treated with Gefitinib European Journal of Cancer (Oxford, England : 1990). May, 2009 | Pubmed ID: 19272767 Inactivation of P53 and Pten Promotes Invasive Bladder Cancer Genes & Development. Mar, 2009 | Pubmed ID: 19261747 Correlation of MR Imaging and MR Spectroscopic Imaging Findings with Ki-67, Phospho-Akt, and Androgen Receptor Expression in Prostate Cancer Radiology. Mar, 2009 | Pubmed ID: 19244047 ETS Rearrangements and Prostate Cancer Initiation Nature. Feb, 2009 | Pubmed ID: 19212347 Differential Requirement of MTOR in Postmitotic Tissues and Tumorigenesis Science Signaling. 2009 | Pubmed ID: 19176516 Gamma-secretase Inhibitors Reverse Glucocorticoid Resistance in T Cell Acute Lymphoblastic Leukemia Nature Medicine. Jan, 2009 | Pubmed ID: 19098907 Comparison of Models to Predict Clinical Failure After Radical Prostatectomy Cancer. Jan, 2009 | Pubmed ID: 19025977 Alveolar Rhabdomyosarcoma: is the Cell of Origin a Mesenchymal Stem Cell? Cancer Letters. Jul, 2009 | Pubmed ID: 19008039 Identification of PMF1 Methylation in Association with Bladder Cancer Progression Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2008 | Pubmed ID: 19088041 P53 is Localized to a Sub-nucleolar Compartment After Proteasomal Inhibition in an Energy-dependent Manner Journal of Cell Science. Dec, 2008 | Pubmed ID: 19033390 Associations Between Variants of the 8q24 Chromosome and Nine Smoking-related Cancer Sites Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Nov, 2008 | Pubmed ID: 18990762 Molecular Alterations Associated with Bladder Cancer Initiation and Progression Scandinavian Journal of Urology and Nephrology. Supplementum. Sep, 2008 | Pubmed ID: 18815930 Targeting AKT/mTOR and ERK MAPK Signaling Inhibits Hormone-refractory Prostate Cancer in a Preclinical Mouse Model The Journal of Clinical Investigation. Sep, 2008 | Pubmed ID: 18725989 Systems Pathology Approach for the Prediction of Prostate Cancer Progression After Radical Prostatectomy Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2008 | Pubmed ID: 18711180 Aberrant Rheb-mediated MTORC1 Activation and Pten Haploinsufficiency Are Cooperative Oncogenic Events Genes & Development. Aug, 2008 | Pubmed ID: 18708577 Chk2 Suppresses the Oncogenic Potential of DNA Replication-associated DNA Damage Molecular Cell. Jul, 2008 | Pubmed ID: 18614044 DLC1 is a Chromosome 8p Tumor Suppressor Whose Loss Promotes Hepatocellular Carcinoma Genes & Development. Jun, 2008 | Pubmed ID: 18519636 Gli Activity Correlates with Tumor Grade in Platelet-derived Growth Factor-induced Gliomas Cancer Research. Apr, 2008 | Pubmed ID: 18381430 A Developmental Model of Sarcomagenesis Defines a Differentiation-based Classification for Liposarcomas The American Journal of Pathology. Apr, 2008 | Pubmed ID: 18310505 TREK-1 is a Novel Molecular Target in Prostate Cancer Cancer Research. Feb, 2008 | Pubmed ID: 18281496 A Context Dependent Role for Wnt Signaling in Tumorigenesis and Stem Cells Cell Cycle (Georgetown, Tex.). Mar, 2008 | Pubmed ID: 18239459 Bax and Bak Do Not Exhibit Functional Redundancy in Mediating Radiation-induced Endothelial Apoptosis in the Intestinal Mucosa International Journal of Radiation Oncology, Biology, Physics. Mar, 2008 | Pubmed ID: 18191336 Genomic and Proteomic Profiles Reveal the Association of Gelsolin to TP53 Status and Bladder Cancer Progression The American Journal of Pathology. Nov, 2007 | Pubmed ID: 17982131 Derivation of Sarcomas from Mesenchymal Stem Cells Via Inactivation of the Wnt Pathway The Journal of Clinical Investigation. Nov, 2007 | Pubmed ID: 17948129 Somatic Cell Type Specific Gene Transfer Reveals a Tumor-promoting Function for P21(Waf1/Cip1) The EMBO Journal. Nov, 2007 | Pubmed ID: 17948060 Declining P53 Function in the Aging Process: a Possible Mechanism for the Increased Tumor Incidence in Older Populations Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17921246 Mutational Loss of PTEN Induces Resistance to NOTCH1 Inhibition in T-cell Leukemia Nature Medicine. Oct, 2007 | Pubmed ID: 17873882 Identification of S664 TSC2 Phosphorylation As a Marker for Extracellular Signal-regulated Kinase Mediated MTOR Activation in Tuberous Sclerosis and Human Cancer Cancer Research. Aug, 2007 | Pubmed ID: 17671177 Highly Efficient Gene Delivery for Bladder Cancers by Intravesically Administered Replication-competent Retroviral Vectors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2007 | Pubmed ID: 17671137 Tissue-specific and Reversible RNA Interference in Transgenic Mice Nature Genetics. Jul, 2007 | Pubmed ID: 17572676 Improved Prediction of Prostate Cancer Recurrence Through Systems Pathology The Journal of Clinical Investigation. Jul, 2007 | Pubmed ID: 17557117 Prognostic Significance of P27Kip1 Expression in Bladder Cancer BJU International. Aug, 2007 | Pubmed ID: 17555476 A Polymorphism in HDM2 (SNP309) Associates with Early Onset in Superficial Tumors, TP53 Mutations, and Poor Outcome in Invasive Bladder Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2007 | Pubmed ID: 17545525 The AKT-mTOR Pathway Plays a Critical Role in the Development of Leiomyosarcomas Nature Medicine. Jun, 2007 | Pubmed ID: 17496901 Molecular Alterations Associated with Bladder Cancer Progression Seminars in Oncology. Apr, 2007 | Pubmed ID: 17382791 Role of the Chromobox Protein CBX7 in Lymphomagenesis Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17374722 Relation Between Human Papillomavirus Positivity and P16 Expression in Head and Neck Carcinomas--a Tissue Microarray Study Anticancer Research. Jan-Feb, 2007 | Pubmed ID: 17352245 Hyperactivation of Ha-ras Oncogene, but Not Ink4a/Arf Deficiency, Triggers Bladder Tumorigenesis The Journal of Clinical Investigation. Feb, 2007 | Pubmed ID: 17256055 Senescence and Tumour Clearance is Triggered by P53 Restoration in Murine Liver Carcinomas Nature. Feb, 2007 | Pubmed ID: 17251933 Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression Cell. Jan, 2007 | Pubmed ID: 17218261 NEDD4-1 is a Proto-oncogenic Ubiquitin Ligase for PTEN Cell. Jan, 2007 | Pubmed ID: 17218260 Technology Insight: Will Systems Pathology Replace the Pathologist? Nature Clinical Practice. Urology. Jan, 2007 | Pubmed ID: 17211424 Mad2 Overexpression Promotes Aneuploidy and Tumorigenesis in Mice Cancer Cell. Jan, 2007 | Pubmed ID: 17189715 Alterations of the Retinoblastoma and P16 Pathway Correlate with Promoter Methylation in Malignant Fibrous Histiocytomas Anticancer Research. Sep-Oct, 2006 | Pubmed ID: 17094467 Evaluation of Ki67, P53 and Angiogenesis in Patients Enrolled in a Randomized Study of Neoadjuvant Chemotherapy with or Without Cystectomy: a Southwest Oncology Group Study Oncology Reports. Oct, 2006 | Pubmed ID: 16969498 PML Inhibits HIF-1alpha Translation and Neoangiogenesis Through Repression of MTOR Nature. Aug, 2006 | Pubmed ID: 16915281 Determinants of Sensitivity and Resistance to Rapamycin-chemotherapy Drug Combinations in Vivo Cancer Research. Aug, 2006 | Pubmed ID: 16885364 Analysis of DNA Mismatch Repair Gene Expression and Mutations in Thyroid Tumours Anticancer Research. May-Jun, 2006 | Pubmed ID: 16827152 Altered Expression of DNA Double-strand Repair Genes Ku70 and Ku80 in Carcinomas of the Oral Cavity Anticancer Research. May-Jun, 2006 | Pubmed ID: 16827151 Comparative Oncogenomics Identifies NEDD9 As a Melanoma Metastasis Gene Cell. Jun, 2006 | Pubmed ID: 16814714 Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach Cell. Jun, 2006 | Pubmed ID: 16814713 Autocrine PDGFR Signaling Promotes Mammary Cancer Metastasis The Journal of Clinical Investigation. Jun, 2006 | Pubmed ID: 16741576 Identification of a Tumour Suppressor Network Opposing Nuclear Akt Function Nature. May, 2006 | Pubmed ID: 16680151 Loss of Ku70/Ku80 Expression Occurs More Frequently in Hereditary Than in Sporadic Colorectal Tumors. Tissue Microarray Study Human Pathology. Apr, 2006 | Pubmed ID: 16564919 Defining Molecular Profiles of Poor Outcome in Patients with Invasive Bladder Cancer Using Oligonucleotide Microarrays Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2006 | Pubmed ID: 16432078 Amplification of CDK4 and MDM2 in Malignant Melanoma Genes, Chromosomes & Cancer. May, 2006 | Pubmed ID: 16419059 Profiling Bladder Cancer Using Targeted Antibody Arrays The American Journal of Pathology. Jan, 2006 | Pubmed ID: 16400012 Differential Exoprotease Activities Confer Tumor-specific Serum Peptidome Patterns The Journal of Clinical Investigation. Jan, 2006 | Pubmed ID: 16395409 [Molecular Protocol for HER2/neu Analysis in Breast Carcinoma] Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Dec, 2005 | Pubmed ID: 16373062 A Novel Logistic Model Based on Clinicopathological Features Predicts Microsatellite Instability in Colorectal Carcinomas Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. Dec, 2005 | Pubmed ID: 16319691 Proposal of a New Grading System for Malignant Fibrous Histiocytomas Anticancer Research. Nov-Dec, 2005 | Pubmed ID: 16309231 Relationship of Nm23 Expression to Proliferation and Prognosis in Malignant Melanomas of the Oral Cavity In Vivo (Athens, Greece). Nov-Dec, 2005 | Pubmed ID: 16277028 Tobacco Smoking, GSTP1 Polymorphism, and Bladder Carcinoma Cancer. Dec, 2005 | Pubmed ID: 16240451 A Novel Multiplexing, Polymerase Chain Reaction-based Assay for the Analysis of Chromosome 18q Status in Colorectal Cancer The Journal of Molecular Diagnostics : JMD. Oct, 2005 | Pubmed ID: 16237217 Gene Expression Profiling in Single Cells Within Tissue Nature Methods. Sep, 2005 | Pubmed ID: 16118636 Evasion of the P53 Tumour Surveillance Network by Tumour-derived MYC Mutants Nature. Aug, 2005 | Pubmed ID: 16094360 Expression of P63 in Diffuse Large B-cell Lymphoma Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Sep, 2005 | Pubmed ID: 16082248 Cytokeratin Expression Correlates with Aneuploidy in Cytological Specimens of Melanoma Metastases Anticancer Research. Jul-Aug, 2005 | Pubmed ID: 16080528 Crucial Role of P53-dependent Cellular Senescence in Suppression of Pten-deficient Tumorigenesis Nature. Aug, 2005 | Pubmed ID: 16079851 Genetic Analysis of Pten and Tsc2 Functional Interactions in the Mouse Reveals Asymmetrical Haploinsufficiency in Tumor Suppression Genes & Development. Aug, 2005 | Pubmed ID: 16027168 A MicroRNA Polycistron As a Potential Human Oncogene Nature. Jun, 2005 | Pubmed ID: 15944707 A Phase I Clinical Trial of the Sequential Combination of Irinotecan Followed by Flavopiridol Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2005 | Pubmed ID: 15897584 Drg1 Expression in 131 Colorectal Liver Metastases: Correlation with Clinical Variables and Patient Outcomes Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2005 | Pubmed ID: 15867226 P73beta-Mediated Apoptosis Requires P57kip2 Induction and IEX-1 Inhibition Cancer Research. Mar, 2005 | Pubmed ID: 15781630 Celecoxib Inhibits Prostate Cancer Growth: Evidence of a Cyclooxygenase-2-independent Mechanism Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2005 | Pubmed ID: 15756026 Safety and Biologic Activity of Intravenous BCL-2 Antisense Oligonucleotide (G3139) and Taxane Chemotherapy in Patients with Advanced Cancer Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Mar, 2005 | Pubmed ID: 15722787 Role of the Proto-oncogene Pokemon in Cellular Transformation and ARF Repression Nature. Jan, 2005 | Pubmed ID: 15662416 Molecular Profiling of Tumor Progression in Head and Neck Cancer Archives of Otolaryngology--head & Neck Surgery. Jan, 2005 | Pubmed ID: 15655179 Application of in Situ Hybridization Probes for MLH-1 and MSH-2 in Tissue Microarrays of Paraffin-embedded Malignant Melanomas: Correlation with Immunohistochemistry and Tumor Stage Human Pathology. Dec, 2004 | Pubmed ID: 15619215 Role of Dok-1 and Dok-2 in Leukemia Suppression The Journal of Experimental Medicine. Dec, 2004 | Pubmed ID: 15611295 Racial Disparity of Epidermal Growth Factor Receptor Expression in Prostate Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2004 | Pubmed ID: 15570072 Glutathione S-transferase P1 Ile105Val Polymorphism, Cigarette Smoking and Prostate Cancer Cancer Detection and Prevention. 2004 | Pubmed ID: 15542263 Genetic and Immunophenotype Analyses of TP53 in Bladder Cancer: TP53 Alterations Are Associated with Tumor Progression Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. Dec, 2004 | Pubmed ID: 15538112 Cytokeratin Positivity in Paraffin-embedded Malignant Melanomas: Comparative Study of KL1, A4 and Lu5 Antibodies Anticancer Research. Sep-Oct, 2004 | Pubmed ID: 15510611 Rb Inactivation Promotes Genomic Instability by Uncoupling Cell Cycle Progression from Mitotic Control Nature. Aug, 2004 | Pubmed ID: 15306814 Preclinical Validation of Anti-TMEFF2-auristatin E-conjugated Antibodies in the Treatment of Prostate Cancer Molecular Cancer Therapeutics. Aug, 2004 | Pubmed ID: 15299075 Caenorhabditis Elegans ABL-1 Antagonizes P53-mediated Germline Apoptosis After Ionizing Irradiation Nature Genetics. Aug, 2004 | Pubmed ID: 15273685 Comparison of DNA Ploidy Status and DNA Ploidy-related Parameters in Malignant Melanoma Tissue Microarrays and Full Sections Human Pathology. Jul, 2004 | Pubmed ID: 15257554 Analysis of Adenomatous Polyposis Coli Gene Expression, APC Locus-microsatellite Instability and APC Promoter Methylation in the Progression of Melanocytic Tumours Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Dec, 2004 | Pubmed ID: 15257316 Hyperphosphorylation of PRb: a Mechanism for RB Tumour Suppressor Pathway Inactivation in Bladder Cancer The Journal of Pathology. Jul, 2004 | Pubmed ID: 15221935 High-resolution Characterization of the Pancreatic Adenocarcinoma Genome Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15199222 Altered Expression and New Mutations in DNA Mismatch Repair Genes MLH1 and MSH2 in Melanoma Brain Metastases Anticancer Research. Mar-Apr, 2004 | Pubmed ID: 15161053 The Translation Factor EIF-4E Promotes Tumor Formation and Cooperates with C-Myc in Lymphomagenesis Nature Medicine. May, 2004 | Pubmed ID: 15098029 Survival Signalling by Akt and EIF4E in Oncogenesis and Cancer Therapy Nature. Mar, 2004 | Pubmed ID: 15029198 Inhibition of Orthotopic Human Bladder Tumor Growth by Lentiviral Gene Transfer of Endostatin Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2004 | Pubmed ID: 15014038 Decreased Retinoid X Receptor-alpha Protein Expression in Basal Cells Occurs in the Early Stage of Human Prostate Cancer Development Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Mar, 2004 | Pubmed ID: 15006913 Application of New in Situ Hybridization Probes for Ku70 and Ku80 in Tissue Microarrays of Paraffin-embedded Malignant Melanomas: Correlation with Immunohistochemical Analysis Human Pathology. Feb, 2004 | Pubmed ID: 14991539 P53 and RB: Simple Interesting Correlates or Tumor Markers of Critical Predictive Nature? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2004 | Pubmed ID: 14981108 Histone Deacetylase Inhibitors: Assays to Assess Effectiveness in Vitro and in Vivo Methods in Enzymology. 2004 | Pubmed ID: 14975307 Loss of the Tumor Suppressor PML in Human Cancers of Multiple Histologic Origins Journal of the National Cancer Institute. Feb, 2004 | Pubmed ID: 14970276 MDM2 and Prognosis Molecular Cancer Research : MCR. Jan, 2004 | Pubmed ID: 14757840 Mutations of the PML Tumor Suppressor Gene in Acute Promyelocytic Leukemia Blood. Mar, 2004 | Pubmed ID: 14630830 Pten Dose Dictates Cancer Progression in the Prostate PLoS Biology. Dec, 2003 | Pubmed ID: 14691534 P73 Expression in Human Normal and Tumor Tissues: Loss of P73alpha Expression is Associated with Tumor Progression in Bladder Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2003 | Pubmed ID: 14654547 Comparison of Gene Expression Profiles in Laser-microdissected, Nonembedded, and OCT-embedded Tumor Samples by Oligonucleotide Microarray Analysis Clinical Chemistry. Dec, 2003 | Pubmed ID: 14633888 Genetic Signatures of Differentiation Induced by 1alpha,25-dihydroxyvitamin D3 in Human Colon Cancer Cells Cancer Research. Nov, 2003 | Pubmed ID: 14633706 P73alpha Regulation by Chk1 in Response to DNA Damage Molecular and Cellular Biology. Nov, 2003 | Pubmed ID: 14585975 Tumor Promotion by Mdm2 Splice Variants Unable to Bind P53 Cancer Research. Sep, 2003 | Pubmed ID: 14522887 Pharmacologic Inactivation of Kinase Suppressor of Ras-1 Abrogates Ras-mediated Pancreatic Cancer Nature Medicine. Oct, 2003 | Pubmed ID: 12960962 Adrenocortical Adenoma and Carcinoma: Histopathological and Molecular Comparative Analysis Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Aug, 2003 | Pubmed ID: 12920217 Tumor Suppressor Role for Myopodin in Bladder Cancer: Loss of Nuclear Expression of Myopodin is Cell-cycle Dependent and Predicts Clinical Outcome Oncogene. Aug, 2003 | Pubmed ID: 12917631 Classification and Subtype Prediction of Adult Soft Tissue Sarcoma by Functional Genomics The American Journal of Pathology. Aug, 2003 | Pubmed ID: 12875988 Gene Discovery in Bladder Cancer Progression Using CDNA Microarrays The American Journal of Pathology. Aug, 2003 | Pubmed ID: 12875971 Altered Expression of P27 and Skp2 Proteins in Prostate Cancer of African-American Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2003 | Pubmed ID: 12855638 A Multigenic Program Mediating Breast Cancer Metastasis to Bone Cancer Cell. Jun, 2003 | Pubmed ID: 12842083 Oncogenes in Melanoma Oncogene. May, 2003 | Pubmed ID: 12789285 Array-based Comparative Genomic Hybridization for Genome-wide Screening of DNA Copy Number in Bladder Tumors Cancer Research. Jun, 2003 | Pubmed ID: 12782593 Lack of P53 Nuclear Immunostaining is Not Indicative of Absence of TP53 Gene Mutations in Colorectal Adenocarcinomas Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Jun, 2003 | Pubmed ID: 12777996 Tumor Response to Radiotherapy Regulated by Endothelial Cell Apoptosis Science (New York, N.Y.). May, 2003 | Pubmed ID: 12750523 Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts Dan Han1, Veronica Rodriguez-Bravo1, Sudeh Izadmehr1, Josep Domingo-Domenech1, Carlos Cordon-Cardo1 1Department of Pathology, Icahn School of Medicine at Mount Sinai JoVE 57011 Cancer Research Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel Lisa Mohr1, Marc Carceles-Cordon1, Jungreem Woo1, Carlos Cordon-Cardo1, Josep Domingo-Domenech1, Veronica Rodriguez-Bravo1,2 1Department of Pathology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 2Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai JoVE 56327 Cancer Research Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells Estrelania S. Williams1, Veronica Rodriguez-Bravo3, Uma Chippada-Venkata2, Janis De Ia Iglesia-Vicente1, Yixuan Gong2, Matthew Galsky2, William Oh2, Carlos Cordon-Cardo1, Josep Domingo-Domenech1 1Department of Pathology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 2Department of Hematology/Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 3Molecular Biology Program, Memorial Sloan-Kettering Cancer Center JoVE 53182 Medicine Isolation of Cancer Stem Cells From Human Prostate Cancer Samples Samuel J. Vidal1, S. Aidan Quinn1, Janis de la Iglesia-Vicente1, Dennis M. Bonal1, Veronica Rodriguez-Bravo2, Adolfo Firpo-Betancourt1, Carlos Cordon-Cardo1, Josep Domingo-Domenech1 1Department of Pathology, Icahn School of Medicine at Mount Sinai, 2Molecular Biology Program, Memorial Sloan-Kettering Cancer Center JoVE 51332 Medicine
Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts Dan Han1, Veronica Rodriguez-Bravo1, Sudeh Izadmehr1, Josep Domingo-Domenech1, Carlos Cordon-Cardo1 1Department of Pathology, Icahn School of Medicine at Mount Sinai JoVE 57011 Cancer Research
Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel Lisa Mohr1, Marc Carceles-Cordon1, Jungreem Woo1, Carlos Cordon-Cardo1, Josep Domingo-Domenech1, Veronica Rodriguez-Bravo1,2 1Department of Pathology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 2Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai JoVE 56327 Cancer Research
Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells Estrelania S. Williams1, Veronica Rodriguez-Bravo3, Uma Chippada-Venkata2, Janis De Ia Iglesia-Vicente1, Yixuan Gong2, Matthew Galsky2, William Oh2, Carlos Cordon-Cardo1, Josep Domingo-Domenech1 1Department of Pathology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 2Department of Hematology/Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 3Molecular Biology Program, Memorial Sloan-Kettering Cancer Center JoVE 53182 Medicine
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples Samuel J. Vidal1, S. Aidan Quinn1, Janis de la Iglesia-Vicente1, Dennis M. Bonal1, Veronica Rodriguez-Bravo2, Adolfo Firpo-Betancourt1, Carlos Cordon-Cardo1, Josep Domingo-Domenech1 1Department of Pathology, Icahn School of Medicine at Mount Sinai, 2Molecular Biology Program, Memorial Sloan-Kettering Cancer Center JoVE 51332 Medicine
