Changyu Zheng Molecular Physiology and Therapeutics Branch National Institute of Dental and Craniofacial Research, NIH, DHHS Biography Publications Institution JoVE Articles Changyu Zheng has not added a biography. If you are Changyu Zheng and would like to personalize this page please email our Author Liaison for assistance. Publications Effects of Human Vascular Endothelial Growth Factor on Reparative Dentin Formation Molecular Medicine Reports. Jan, 2016 | Pubmed ID: 26647730 Essential Role of Carbonic Anhydrase XII in Secretory Gland Fluid and HCO3 (-) Secretion Revealed by Disease Causing Human Mutation The Journal of Physiology. Dec, 2015 | Pubmed ID: 26486891 Inhibition of Autophagy by 3-MA Enhances IL-24-induced Apoptosis in Human Oral Squamous Cell Carcinoma Cells Journal of Experimental & Clinical Cancer Research : CR. 2015 | Pubmed ID: 26361755 Advances in Salivary Gland Gene Therapy - Oral and Systemic Implications Expert Opinion on Biological Therapy. 2015 | Pubmed ID: 26149284 STIM2 Enhances Receptor-stimulated Ca²⁺ Signaling by Promoting Recruitment of STIM1 to the Endoplasmic Reticulum-plasma Membrane Junctions Science Signaling. Jan, 2015 | Pubmed ID: 25587190 Assessment of Transfection of AdCMV-EGFP to Rat Submandibular Gland Cells Cell Biochemistry and Biophysics. Jan, 2015 | Pubmed ID: 25108736 Integration of the Hybrid Adenoretroviral Vector AdLTR-luc Involves Both MoMLV Elements Flanking the Transgene International Journal of Medical Sciences. 2014 | Pubmed ID: 24936143 Efficiently Engineered Cell Sheet Using a Complex of Polyethylenimine-alginate Nanocomposites Plus Bone Morphogenetic Protein 2 Gene to Promote New Bone Formation International Journal of Nanomedicine. 2014 | Pubmed ID: 24855355 All Human EF1α Promoters Are Not Equal: Markedly Affect Gene Expression in Constructs from Different Sources International Journal of Medical Sciences. 2014 | Pubmed ID: 24688302 Toxicity and Biodistribution of the Serotype 2 Recombinant Adeno-associated Viral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Mouse Parotid Gland PloS One. 2014 | Pubmed ID: 24667436 Antitumor Effect of TRAIL on Oral Squamous Cell Carcinoma Using Magnetic Nanoparticle-mediated Gene Expression Cell Biochemistry and Biophysics. Jul, 2014 | Pubmed ID: 24563116 Enhancement of Osteoinduction by Continual Simvastatin Release from Poly(lactic-co-glycolic Acid)-hydroxyapatite-simvastatin Nano-fibrous Scaffold Journal of Biomedical Nanotechnology. Nov, 2013 | Pubmed ID: 24059091 Using Poly(lactic-co-glycolic Acid) Microspheres to Encapsulate Plasmid of Bone Morphogenetic Protein 2/polyethylenimine Nanoparticles to Promote Bone Formation in Vitro and in Vivo International Journal of Nanomedicine. 2013 | Pubmed ID: 23990717 MiR-150 Promotes Renal Fibrosis in Lupus Nephritis by Downregulating SOCS1 Journal of the American Society of Nephrology : JASN. Jun, 2013 | Pubmed ID: 23723424 Expression and Secretion of Human Proinsulin-B10 from Mouse Salivary Glands: Implications for the Treatment of Type I Diabetes Mellitus PloS One. 2013 | Pubmed ID: 23554999 Irbit Mediates Synergy Between Ca(2+) and CAMP Signaling Pathways During Epithelial Transport in Mice Gastroenterology. Jul, 2013 | Pubmed ID: 23542070 Loss of TRPM2 Function Protects Against Irradiation-induced Salivary Gland Dysfunction Nature Communications. 2013 | Pubmed ID: 23443543 Recovery of Radiation-induced Dry Eye and Corneal Damage by Pretreatment with Adenoviral Vector-mediated Transfer of Erythropoietin to the Salivary Glands in Mice Human Gene Therapy. Apr, 2013 | Pubmed ID: 23402345 Impairment of TRPC1-STIM1 Channel Assembly and AQP5 Translocation Compromise Agonist-stimulated Fluid Secretion in Mice Lacking Caveolin1 Journal of Cell Science. Jan, 2013 | Pubmed ID: 23203809 Antitumor Effect of Human TRAIL on Adenoid Cystic Carcinoma Using Magnetic Nanoparticle-mediated Gene Expression Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2013 | Pubmed ID: 22633896 Early Responses to Adenoviral-mediated Transfer of the Aquaporin-1 CDNA for Radiation-induced Salivary Hypofunction Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23129637 A Novel Hybrid Adenoretroviral Vector with More Extensive E3 Deletion Extends Transgene Expression in Submandibular Glands Human Gene Therapy Methods. Jun, 2012 | Pubmed ID: 22817829 Sustained Exendin-4 Secretion Through Gene Therapy Targeting Salivary Glands in Two Different Rodent Models of Obesity/type 2 Diabetes PloS One. 2012 | Pubmed ID: 22808093 Sialin (SLC17A5) Functions As a Nitrate Transporter in the Plasma Membrane Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22778404 从辐射 ± 顺铂所致口腔黏膜炎的药理作用保护。 International Journal of Radiation Oncology, Biology, Physics. Dec, 2011 | Pubmed ID: 22197226 安全评估和体内分布的受规管的 AAV2 基因对小鼠颌下腺交货后转移载体。 Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2011 | Pubmed ID: 21625005 防止辐射诱导涎腺功能减退后小鼠颌下腺 HKGF 基因转染。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21367751 小型猪腮腺微血管内皮细胞对辐射的影响。 International Journal of Radiation Oncology, Biology, Physics. Nov, 2010 | Pubmed ID: 20832188 涎腺疾病的基因治疗。 Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20717774 系统性传递生物活性胰高血糖素样肽-1 后腺病毒介导的基因转移在小鼠的涎腺。 Endocrinology. Sep, 2010 | Pubmed ID: 20610567 涎腺上皮细胞: 谦逊的目标站点的基因疗法。 The International Journal of Biochemistry & Cell Biology. Jun, 2010 | Pubmed ID: 20219693 条件表达的 TGF Beta1 扰乱了鼠标涎腺发育和功能。 Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2010 | Pubmed ID: 20142803 生产和排序的转基因,修改人甲状旁腺素在大鼠涎腺的体内。 Biochemical and Biophysical Research Communications. Jan, 2010 | Pubmed ID: 19944067 E1 含有腺病毒在唾液中的第一代的腺病毒载体传递到人类腮腺后的瞬态检测。 The Journal of Gene Medicine. Jan, 2010 | Pubmed ID: 19941317 辐射诱导涎腺功能减退基因转移基础治疗的发展。 Oral Oncology. Jan, 2010 | Pubmed ID: 19892587 腺病毒介导的人类 TRAIL 基因与端粒酶肿瘤特异性启动子驱动的腺样囊性癌诱导细胞凋亡。 Cancer Biology & Therapy. May, 2009 | Pubmed ID: 19587531 腺病毒载体介导转入角质形成细胞生长因子基因的小鼠颌下腺后辐射引起口腔黏膜炎的预防。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2009 | Pubmed ID: 19584147 体内分泌的大鼠颌下腺从小鼠免疫球蛋白 G Fc 片段。 The Journal of Gene Medicine. Jul, 2009 | Pubmed ID: 19424985 长期转导的微型猪腮腺 2 血清型腺相关病毒载体。 The Journal of Gene Medicine. Jun, 2009 | Pubmed ID: 19326368 水通道蛋白-1 基因转移来纠正辐射诱导涎腺功能减退。 Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19096789 腺病毒介导的基因转移后转基因恒河猕猴腮腺分泌蛋白的排序。 Human Gene Therapy. Dec, 2008 | Pubmed ID: 18764738 生长激素促红细胞生成素融合蛋白在大鼠涎腺中的排序。 Biochemical and Biophysical Research Communications. Aug, 2008 | Pubmed ID: 18544341 对启动子的组织特异性基因交付使用的评价。 Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18470647 延长转基因表达从 Nonintegrating 的腺病毒载体逆转录病毒的元素。 Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2008 | Pubmed ID: 18388914 转基因的促红细胞生成素增长激素融合蛋白在小鼠涎腺的排序行为。 Human Gene Therapy. Mar, 2008 | Pubmed ID: 18303958 腺相关病毒类型 12 (AAV12): 与唾液酸和乙酰肝素硫酸多糖独立转导活性的新型腺相关病毒血清型。 Journal of Virology. Feb, 2008 | Pubmed ID: 18045941 小型猪腮腺腺病毒介导的基因转移之后转基因分泌蛋白的排序。 The Journal of Gene Medicine. Sep, 2007 | Pubmed ID: 17654745 雌性小鼠的更容易发生发展受损转化生长因子 β 信号涎腺炎症功能障碍。 Arthritis and Rheumatism. Jun, 2007 | Pubmed ID: 17530708 腺相关病毒血清型 2 介导的基因转移到非人类灵长类的腮腺。 Human Gene Therapy. Feb, 2007 | Pubmed ID: 17328682 毒性和体内分布的第一代的重组腺病毒载体,编码向单个大鼠颌下腺 Retroductal 交付后的水通道蛋白-1。 Human Gene Therapy. Nov, 2006 | Pubmed ID: 17069536 更正的辐射诱导涎腺功能减退的水通道蛋白 1 基因的转移。 Biochimica Et Biophysica Acta. Aug, 2006 | Pubmed ID: 16368071 工程的肿瘤细胞分泌基质细胞衍生因子-1 的疫苗诱导的 T 细胞依赖的抗肿瘤反应。 Cancer Biotherapy & Radiopharmaceuticals. Aug, 2005 | Pubmed ID: 16114988 用于基因传递到涎腺病毒性和哺乳动物宣传员的评价。 Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2005 | Pubmed ID: 16099414 巨大肿瘤回归微胶囊化重组肿瘤细胞分泌融合蛋白所致。 Cancer Biotherapy & Radiopharmaceuticals. Jun, 2005 | Pubmed ID: 15989471 涎腺作为基因治疗学的一些单亲的内分泌失调的潜在基因转移目标。 The Journal of Endocrinology. Jun, 2005 | Pubmed ID: 15930162 以下编码 CD40 配体的腺病毒载体的未成熟树突状细胞瘤体内注射引起重大回归的既定发性骨髓瘤。 Cancer Gene Therapy. Feb, 2005 | Pubmed ID: 15565183 组合阿尔法肿瘤坏死因子基因治疗和工程的树突状细胞疫苗在打击公认的肿瘤。 The Journal of Gene Medicine. Aug, 2004 | Pubmed ID: 15293344 重新设计的涎腺是稳定内源性生物反应器的系统性的基因疗法。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14978265 载体介导的基因转移研究进展。 Immunology Letters. Dec, 2003 | Pubmed ID: 14687716 上游莫洛尼鼠白血病病毒要素列入 E1 删除腺病毒转基因卡带的导致上皮细胞异常基因组整合。 Virology. Sep, 2003 | Pubmed ID: 12954213 分布和成年大鼠的单一涎腺病毒载体管理而引起的毒性。 Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. Aug, 2003 | Pubmed ID: 12846788 集成的混合 Adenoretroviral 矢量的效率。 Biochemical and Biophysical Research Communications. Jan, 2003 | Pubmed ID: 12480529 对涎腺的基因转移。 International Review of Cytology. 2002 | Pubmed ID: 11837896 混合载体感染后的长期表达 AdLTR 吕克是从综合转基因。 Biochemical and Biophysical Research Communications. Feb, 2002 | Pubmed ID: 11829458 Retroductal颌下腺灌输和本地化分割照射在涎腺功能减退症大鼠模型 Renjith Parameswaran Nair1, Changyu Zheng2, Gulshan Sunavala-Dossabhoy1 1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 2Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, DHHS Medicine 沃顿商学院的导管插管通过小鼠颌下腺唾液腺 Yusuke Kuriki1, Younan Liu1, Dengsheng Xia1, Eva M. Gjerde1, Saeed Khalili1, Brennan Mui1, Changyu Zheng2, Simon D. Tran1 1Faculty of Dentistry, McGill University, 2National Institutes of Health, Bethesda, MD, USA JoVE 3074 Medicine
Retroductal颌下腺灌输和本地化分割照射在涎腺功能减退症大鼠模型 Renjith Parameswaran Nair1, Changyu Zheng2, Gulshan Sunavala-Dossabhoy1 1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 2Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, DHHS Medicine
沃顿商学院的导管插管通过小鼠颌下腺唾液腺 Yusuke Kuriki1, Younan Liu1, Dengsheng Xia1, Eva M. Gjerde1, Saeed Khalili1, Brennan Mui1, Changyu Zheng2, Simon D. Tran1 1Faculty of Dentistry, McGill University, 2National Institutes of Health, Bethesda, MD, USA JoVE 3074 Medicine