Cheryl Ackert-Bicknell Department of Orthopaedics University of Rochester Biography Publications Institution JoVE Articles Cheryl Ackert-Bicknell has not added a biography. If you are Cheryl Ackert-Bicknell and would like to personalize this page please email our Author Liaison for assistance. Publications Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2016 | Pubmed ID: 27476799 Genome-wide Association Study of Behavioral, Physiological and Gene Expression Traits in Outbred CFW Mice Nature Genetics. Aug, 2016 | Pubmed ID: 27376237 Genetics of Aging Bone Mammalian Genome : Official Journal of the International Mammalian Genome Society. Aug, 2016 | Pubmed ID: 27272104 How Do Bisphosphonates Affect Fracture Healing? Injury. Jan, 2016 | Pubmed ID: 26768295 Passenger Gene Mutations: Unwanted Guests in Genetically Modified Mice Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Feb, 2016 | Pubmed ID: 26684928 Genetic Determinants of Fibro-osseous Lesions in Aged Inbred Mice Experimental and Molecular Pathology. Feb, 2016 | Pubmed ID: 26589134 Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2016 | Pubmed ID: 25533306 Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination PLoS Genetics. Nov, 2015 | Pubmed ID: 26523602 Whole-genome Sequencing Identifies EN1 As a Determinant of Bone Density and Fracture Nature. Oct, 2015 | Pubmed ID: 26367794 Genetic Regulation of Bone Strength: a Review of Animal Model Studies BoneKEy Reports. 2015 | Pubmed ID: 26157577 Aging Research Using Mouse Models Current Protocols in Mouse Biology. 2015 | Pubmed ID: 26069080 Fixation Stability Dictates the Differentiation Pathway of Periosteal Progenitor Cells in Fracture Repair Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2015 | Pubmed ID: 25639792 Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment PLoS Genetics. Jun, 2014 | Pubmed ID: 24945404 Spontaneous Voiding by Mice Reveals Strain-specific Lower Urinary Tract Function to Be a Quantitative Genetic Trait American Journal of Physiology. Renal Physiology. Jun, 2014 | Pubmed ID: 24717733 Impact of the Environment on the Skeleton: is It Modulated by Genetic Factors? Current Osteoporosis Reports. Sep, 2013 | Pubmed ID: 23846556 Modeling Hepatic Osteodystrophy in Abcb4 Deficient Mice Bone. Aug, 2013 | Pubmed ID: 23545228 Recalculation of 23 Mouse HDL QTL Datasets Improves Accuracy and Allows for Better Candidate Gene Analysis Journal of Lipid Research. Apr, 2013 | Pubmed ID: 23393305 The Need for Mouse Models in Osteoporosis Genetics Research BoneKEy Reports. 2012 | Pubmed ID: 23951485 Canonical A-to-I and C-to-U RNA Editing is Enriched at 3'UTRs and MicroRNA Target Sites in Multiple Mouse Tissues PloS One. 2012 | Pubmed ID: 22448268 Genetic Variation in TRPS1 May Regulate Hip Geometry As Well As Bone Mineral Density Bone. May, 2012 | Pubmed ID: 22306695 HDL Cholesterol and Bone Mineral Density: is There a Genetic Link? Bone. Feb, 2012 | Pubmed ID: 21810493 Genetic Analysis in the Collaborative Cross Breeding Population Genome Research. Aug, 2011 | Pubmed ID: 21734011 BMD Regulation on Mouse Distal Chromosome 1, Candidate Genes, and Response to Ovariectomy or Dietary Fat Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2011 | Pubmed ID: 20687154 Functional Genomics Complements Quantitative Genetics in Identifying Disease-gene Associations PLoS Computational Biology. 2010 | Pubmed ID: 21085640 A Circadian-regulated Gene, Nocturnin, Promotes Adipogenesis by Stimulating PPAR-gamma Nuclear Translocation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20498072 Nocturnin: a Circadian Target of Pparg-induced Adipogenesis Annals of the New York Academy of Sciences. Mar, 2010 | Pubmed ID: 20392228 Mouse BMD Quantitative Trait Loci Show Improved Concordance with Human Genome-wide Association Loci when Recalculated on a New, Common Mouse Genetic Map Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2010 | Pubmed ID: 20200990 A New Standard Genetic Map for the Laboratory Mouse Genetics. Aug, 2009 | Pubmed ID: 19535546 Marrow Fat and the Bone Microenvironment: Developmental, Functional, and Pathological Implications Critical Reviews in Eukaryotic Gene Expression. 2009 | Pubmed ID: 19392647 Strain-specific Effects of Rosiglitazone on Bone Mass, Body Composition, and Serum Insulin-like Growth Factor-I Endocrinology. Mar, 2009 | Pubmed ID: 18948404 PPARG by Dietary Fat Interaction Influences Bone Mass in Mice and Humans Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Sep, 2008 | Pubmed ID: 18707223 A Chromosomal Inversion Within a Quantitative Trait Locus Has a Major Effect on Adipogenesis and Osteoblastogenesis Annals of the New York Academy of Sciences. Nov, 2007 | Pubmed ID: 17584978 Mapping Genetic Loci That Regulate Lipid Levels in a NZB/B1NJxRF/J Intercross and a Combined Intercross Involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J Mouse Strains Journal of Lipid Research. Aug, 2007 | Pubmed ID: 17496333 Genetic Dissection of Mouse Distal Chromosome 1 Reveals Three Linked BMD QTLs with Sex-dependent Regulation of Bone Phenotypes Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2007 | Pubmed ID: 17451375 The Genetics of PPARG and the Skeleton PPAR Research. 2006 | Pubmed ID: 17347532 Femur Mechanical Properties in the F2 Progeny of an NZB/B1NJ X RF/J Cross Are Regulated Predominantly by Genetic Loci That Regulate Bone Geometry Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2006 | Pubmed ID: 16869724 Genetic Increase in Serum Insulin-like Growth Factor-I (IGF-I) in C3H/HeJ Compared with C57BL/6J Mice is Associated with Increased Transcription from the IGF-I Exon 2 Promoter Endocrinology. Jun, 2006 | Pubmed ID: 16527837 Chromosomal Inversion Discovered in C3H/HeJ Mice Genomics. Feb, 2006 | Pubmed ID: 16309882 Genetic Variation in Femur Extrinsic Strength in 29 Different Inbred Strains of Mice is Dependent on Variations in Femur Cross-sectional Geometry and Bone Density Bone. Jan, 2005 | Pubmed ID: 15664009 Allelic Differences in a Quantitative Trait Locus Affecting Insulin-like Growth Factor-I Impact Skeletal Acquisition and Body Composition Pediatric Nephrology (Berlin, Germany). Mar, 2005 | Pubmed ID: 15549416 Congenic Mice with Low Serum IGF-I Have Increased Body Fat, Reduced Bone Mineral Density, and an Altered Osteoblast Differentiation Program Bone. Nov, 2004 | Pubmed ID: 15542029 Nitric Oxide Regulates Receptor Activator of Nuclear Factor-kappaB Ligand and Osteoprotegerin Expression in Bone Marrow Stromal Cells Endocrinology. Feb, 2004 | Pubmed ID: 14563699 High-resolution Genetic Map of X-linked Juvenile-type Granulosa Cell Tumor Susceptibility Genes in Mouse Cancer Research. Dec, 2003 | Pubmed ID: 14678975 Circulating Levels of IGF-1 Directly Regulate Bone Growth and Density The Journal of Clinical Investigation. Sep, 2002 | Pubmed ID: 12235108 High-Throughput, Multi-Image Cryohistology of Mineralized Tissues Nathaniel A. Dyment1, Xi Jiang1, Li Chen1, Seung-Hyun Hong2, Douglas J. Adams3, Cheryl Ackert-Bicknell4, Dong-Guk Shin2, David W. Rowe1 1Department of Reconstructive Sciences, University of Connecticut Health Center, 2Department of Computer Science and Engineering, University of Connecticut, 3Department of Orthopaedic Surgery, University of Connecticut Health Center, 4Department of Orthopaedics, University of Rochester JoVE 54468 Biology
High-Throughput, Multi-Image Cryohistology of Mineralized Tissues Nathaniel A. Dyment1, Xi Jiang1, Li Chen1, Seung-Hyun Hong2, Douglas J. Adams3, Cheryl Ackert-Bicknell4, Dong-Guk Shin2, David W. Rowe1 1Department of Reconstructive Sciences, University of Connecticut Health Center, 2Department of Computer Science and Engineering, University of Connecticut, 3Department of Orthopaedic Surgery, University of Connecticut Health Center, 4Department of Orthopaedics, University of Rochester JoVE 54468 Biology