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Articles by Cicely L. Williams in JoVE

 JoVE Clinical and Translational Medicine

肠系膜动脉收缩和舒张的研究,使用自动线Myography


JoVE 3119 9/22/2011

1Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, 2Department of Biology, North Carolina Central University, Durham, 3Department of Physiology & Pharmacology and Hypertension & Vascular Research Center, Wake Forest University School of Medicine

一个孤立的肠系膜动脉的力测量的自动化myography方法描述。它采用一个Mulvany哈尔彭自动双丝肌动描记510A福林和钙,以确定响应。该方法允许等距反应一致,以激动剂决心在小血管的直径为60 - 300微米,独立。

Other articles by Cicely L. Williams on PubMed

对肾间质钙噻嗪类的操作。

Thiazides 增加尿钠排泄,虽然他们也减少尿钙的排泄。最近在我们的实验室的研究表明增加膳食盐大大减少了达尔盐敏感 (DS) 大鼠,间质液的钙,这是与血压升高相关联及增加尿钙的排泄。由于血管舒张增加细胞外液的钙的行动,我们推想氢氯噻嗪 (HCTZ) 常用噻嗪类、 抗高血压作用可能是由于减少尿钙的排泄增加间质液的钙的结果。

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