Darren W. Begley Group Leader I Emerald Bio Biography Publications Institution JoVE Articles Darren W. Begley has not added a biography. If you are Darren W. Begley and would like to personalize this page please email our Author Liaison for assistance. Publications Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome PloS One. 2013 | Pubmed ID: 23382856 A Small-molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-like Fragments Journal of Molecular Biology. Jul, 2011 | Pubmed ID: 21763501 Fragment Screening of Infectious Disease Targets in a Structural Genomics Environment Methods in Enzymology. 2011 | Pubmed ID: 21371605 Predicting the Success of Fragment Screening by X-ray Crystallography Methods in Enzymology. 2011 | Pubmed ID: 21371588 Leveraging Structure Determination with Fragment Screening for Infectious Disease Drug Targets: MECP Synthase from Burkholderia Pseudomallei Journal of Structural and Functional Genomics. Jul, 2011 | Pubmed ID: 21359640 Fragment-based Discovery of Novel Thymidylate Synthase Leads by NMR Screening and Group Epitope Mapping Chemical Biology & Drug Design. Sep, 2010 | Pubmed ID: 20626411 Locking out Viral Replication Nature Chemical Biology. Nov, 2009 | Pubmed ID: 19841624 Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit Brianna L. Armour*1, Steve R. Barnes*2, Spencer O. Moen2, Eric Smith3, Amy C. Raymond4, James W. Fairman5, Lance J. Stewart6, Bart L. Staker7, Darren W. Begley5, Thomas E. Edwards8, Donald D. Lorimer9 1Protein Crystallization Lab, Emerald Bio, 2Molecular Biology Lab, Emerald Bio, 3Scientific Sales Representative, Emerald Bio, 4Group Leader II, Emerald Bio, 5Group Leader I, Emerald Bio, 6Chair of Advisory Board, Emerald Bio, 7Director of Multi-Target Services, Emerald Bio, 8Senior Project Leader, Emerald Bio, 9Project Leader II & SSGCID Site Manager, Emerald Bio JoVE 4225 Immunology and Infection
Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit Brianna L. Armour*1, Steve R. Barnes*2, Spencer O. Moen2, Eric Smith3, Amy C. Raymond4, James W. Fairman5, Lance J. Stewart6, Bart L. Staker7, Darren W. Begley5, Thomas E. Edwards8, Donald D. Lorimer9 1Protein Crystallization Lab, Emerald Bio, 2Molecular Biology Lab, Emerald Bio, 3Scientific Sales Representative, Emerald Bio, 4Group Leader II, Emerald Bio, 5Group Leader I, Emerald Bio, 6Chair of Advisory Board, Emerald Bio, 7Director of Multi-Target Services, Emerald Bio, 8Senior Project Leader, Emerald Bio, 9Project Leader II & SSGCID Site Manager, Emerald Bio JoVE 4225 Immunology and Infection
