David M. Langenau Molecular Pathology, Cancer Center and Center for Regenerative Medicine Massachusetts General Hospital Biography Publications Institution JoVE Articles David M. Langenau has not added a biography. If you are David M. Langenau and would like to personalize this page please email our Author Liaison for assistance. Publications Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies Cold Spring Harbor Perspectives in Medicine. 2014 | Pubmed ID: 25368019 Optimized Cell Transplantation Using Adult Rag2 Mutant Zebrafish Nature Methods. Aug, 2014 | Pubmed ID: 25042784 Lineage of Origin in Rhabdomyosarcoma Informs Pharmacological Response Genes & Development. Jul, 2014 | Pubmed ID: 25030697 Zebrafish As a Model to Assess Cancer Heterogeneity, Progression and Relapse Disease Models & Mechanisms. Jul, 2014 | Pubmed ID: 24973745 Glycogen Synthase Kinase 3 Inhibitors Induce the Canonical WNT/β-catenin Pathway to Suppress Growth and Self-renewal in Embryonal Rhabdomyosarcoma Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706870 Loss of Function Tp53 Mutations Do Not Accelerate the Onset of Myc-induced T-cell Acute Lymphoblastic Leukaemia in the Zebrafish British Journal of Haematology. Jul, 2014 | Pubmed ID: 24690081 Clonal Evolution Enhances Leukemia-propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia Through Akt/mTORC1 Pathway Activation Cancer Cell. Mar, 2014 | Pubmed ID: 24613413 Pten Regulates Zebrafish Hematopoiesis Blood. Jan, 2014 | Pubmed ID: 24408201 Cross-species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma PLoS Genetics. Aug, 2013 | Pubmed ID: 24009521 Zebrafish Rhabdomyosarcoma Reflects the Developmental Stage of Oncogene Expression During Myogenesis Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23821038 The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish PloS One. 2013 | Pubmed ID: 23705022 A Novel Chemical Screening Strategy in Zebrafish Identifies Common Pathways in Embryogenesis and Rhabdomyosarcoma Development Development (Cambridge, England). Jun, 2013 | Pubmed ID: 23615277 Through the Looking Glass: Visualizing Leukemia Growth, Migration, and Engraftment Using Fluorescent Transgenic Zebrafish Advances in Hematology. 2012 | Pubmed ID: 22829834 Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-like Effector Nucleases (TALENs) PloS One. 2012 | Pubmed ID: 22655075 In Vivo Imaging of Tumor-propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma Cancer Cell. May, 2012 | Pubmed ID: 22624717 Sarkome in Diskrete Teilmengen Von Prospektiv Isoliert Skelettmuskel-Zellen Induziert Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22135462 Fluoreszierende Bildgebung Der Krebs Im Zebrafisch Methods in Cell Biology. 2011 | Pubmed ID: 21951542 Zebrafisch-Modelle Der Rhabdomyosarkom Methods in Cell Biology. 2011 | Pubmed ID: 21951539 Hochdurchsatz-Bildgebung Der Erwachsenen Fluoreszierende Zebrafish Mit Einer LED-Fluoreszenz-Makroskop Nature Protocols. Feb, 2011 | Pubmed ID: 21293462 Auswahl-freie Zink-Finger-Nuklease-Ingenieur Von Kontext-abhängige Assembly (CoDA) Nature Methods. Jan, 2011 | Pubmed ID: 21151135 T-Lymphoblastische Lymphome Zellen Schnelles Hohe BCL2, S1P1 Und ICAM1, Was Zu Einer Blockade Der Tumor Zelle Intravasation Cancer Cell. Oct, 2010 | Pubmed ID: 20951945 Überraschen-Ing-Werkzeuge Für Die Mosaik-Analyse Im Zebrafisch Nature Methods. Mar, 2010 | Pubmed ID: 20195251 Transplantation Von Hochdurchsatz-legt Fest, Dass Zellen Tumor-Einleitung Im Zebrafisch T-Zell Leukämie, Akute Lymphoblastische Reichlich Vorhanden Sind Blood. Apr, 2010 | Pubmed ID: 20056790 Zebrafisch Als Modell Für Krebs Selbsterneuerung Zebrafish. Dec, 2009 | Pubmed ID: 19954344 Bau Und Anwendung Einer Zebrafisch-Array-vergleichende Genomische Hybridisierung-Plattform Genes, Chromosomes & Cancer. Feb, 2009 | Pubmed ID: 18973135 Generierung Und Charakterisierung Von Transgenen Zebrafisch-Linien Mit Unterschiedliche Allgegenwärtige Promotoren Transgenic Research. Apr, 2008 | Pubmed ID: 17968670 Hitzeschock Induktion Von T-Zell-Lymphom/Leukämie Bei Bedingten Cre/Lox-regulierten Transgene Zebrabärbling British Journal of Haematology. Jul, 2007 | Pubmed ID: 17593023 Hitze-Schock-inducible Cre/Lox-Ansätze, Um Verschiedene Arten Von Tumoren Und Hyperplasie in Transgenen Zebrafisch Induzieren Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17517602 Auswirkungen Auf Die Entstehung Von Rhabdomyosarkom, Embryonales RAS Genes & Development. Jun, 2007 | Pubmed ID: 17510286 Cre / Lox-regulierten Transgenen Zebrafisch-Modell Mit Bedingten Myc-induzierten T-Zell Akuter Lymphatischer Leukämie Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15827121 Der Zebrafisch: Ein Neues Modell Der T-Zell-Entwicklung Und Thymus Nature Reviews. Immunology. Apr, 2005 | Pubmed ID: 15803150 Unterdrückung Der Apoptose Durch Bcl-2-Überexpression in Lymphoiden Zellen Transgene Zebrafisch Blood. Apr, 2005 | Pubmed ID: 15618471 Auswirkungen Der Tödlichen Strahlung Im Zebrafisch Und Rettung Von Hämatopoetischen Stammzelltransplantation Blood. Sep, 2004 | Pubmed ID: 15142873 In Vivo Verfolgung Von T-Zell-Entwicklung, Ablation Und Verpflanzung in Transgenen Zebrafisch Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15123839 Die Verwendung Von Zebrafisch, Um Immunität Zu Verstehen Immunity. Apr, 2004 | Pubmed ID: 15084267 Knockdown Von Zebrafisch FANCD2 Verursacht Missbildungen über P53-abhängige Apoptose Developmental Cell. Dec, 2003 | Pubmed ID: 14667412 Myc-induzierte T-Zell-Leukämie in Transgenen Zebrafisch Science (New York, N.Y.). Feb, 2003 | Pubmed ID: 12574629 Normalen und malignen Muscle Cell Transplantation in immungeschwächten Adult Zebrafisch Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection Die Quantifizierung der Häufigkeit von Tumor-Ausbreitung Cells Mit Limiting Dilution Cell Transplantation in Syngene Zebrafisch Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology
Normalen und malignen Muscle Cell Transplantation in immungeschwächten Adult Zebrafisch Inês M. Tenente*1,2,3, Qin Tang*1,2, John C. Moore1,2, David M. Langenau1,2 1Molecular Pathology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, 2Harvard Stem Cell Institute, 3GABBA - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Immunology and Infection
Die Quantifizierung der Häufigkeit von Tumor-Ausbreitung Cells Mit Limiting Dilution Cell Transplantation in Syngene Zebrafisch Jessica S. Blackburn1, Sali Liu1, David M. Langenau2 1Department of Molecular Pathology, Massachusetts General Hospital, Harvard Medical School, 2Department of Molecular Pathology, Massachusetts General Hospital Cancer Center, Harvard Stem Cell Institute JoVE 2790 Biology