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In JoVE (1)
Other Publications (2)
Articles by David R. Duhamel in JoVE
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
David R. Duhamel1, Jeff B. Hales2
1Director of Pulmonary Special Procedures and the Lung Cancer Center, Virginia Hospital Center, 2Chief, Division of Pulmonary Critical Care and Sleep Medicine, Virginia Hospital Center
Bronchial thermoplasty is a non-drug procedure for severe persistent asthma that delivers thermal energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle. Reducing airway smooth muscle decreases the ability of the airways to constrict, thereby reducing the frequency of asthma attacks.
Other articles by David R. Duhamel on PubMed
Nonneoplastic Lesions of the Tracheobronchial Wall: Radiologic Findings with Bronchoscopic Correlation
Radiographics : a Review Publication of the Radiological Society of North America, Inc. Oct, 2002 | Pubmed ID: 12376612
Nonneoplastic diseases of the central airways are uncommon but can be categorized as either focal or diffuse, although there is some overlap. Focal diseases include postintubation stenosis, postinfectious stenosis, posttransplantation stenosis, and various systemic diseases that may involve the airways and lead to focal stenosis (eg, Crohn disease, sarcoidosis, Behçet syndrome). Diffuse diseases of the central airways include Wegener granulomatosis, relapsing polychondritis, tracheobronchopathia osteochondroplastica, amyloidosis, papillomatosis, and rhinoscleroma. Conventional radiography is often the first step in the evaluation of suspected central airway disease and may be adequate in itself to identify the abnormality. However, computed tomography (CT) improves both the detection and characterization of central airway disease. Bronchoscopy remains the primary procedure for the diagnostic work-up of these disease entities. Nevertheless, a thorough radiologic evaluation with radiography and CT may demonstrate specific imaging findings (eg, calcification) that can help narrow the differential diagnosis and aid in the planning of bronchoscopy or therapeutic intervention.
Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma: a Multicenter, Randomized, Double-blind, Sham-controlled Clinical Trial
American Journal of Respiratory and Critical Care Medicine. Jan, 2010 | Pubmed ID: 19815809
Bronchial thermoplasty (BT) is a bronchoscopic procedure in which controlled thermal energy is applied to the airway wall to decrease smooth muscle.