Dirk P Dittmer Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, Center for AIDS Research University of North Carolina at Chapel Hill Biography Publications Institution JoVE Articles Dirk P Dittmer has not added a biography. If you are Dirk P Dittmer and would like to personalize this page please email our Author Liaison for assistance. Publications Latent KSHV Infection of Monocytes Downregulates Expression of Adaptive Immune Response Costimulatory Receptors and Proinflammatory Cytokine Expression Journal of Virology. Jan, 2012 | Pubmed ID: 22278234 Rapalogs in Viral Cancers Expert Opinion on Investigational Drugs. Feb, 2012 | Pubmed ID: 22214523 Cytokine Homologs of Human Gammaherpesviruses Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Feb, 2012 | Pubmed ID: 22142220 Rapamycin with Antiretroviral Therapy in AIDS-Associated Kaposi Sarcoma: An AIDS Malignancy Consortium Study Journal of Acquired Immune Deficiency Syndromes (1999). Nov, 2011 | Pubmed ID: 22067664 Restricted Kaposi's Sarcoma (KS) Herpesvirus Transcription in KS Lesions from Patients on Successful Antiretroviral Therapy MBio. 2011 | Pubmed ID: 22045987 Phosphatase and Tensin Homolog on Chromosome 10 is Phosphorylated in Primary Effusion Lymphoma and Kaposi's Sarcoma The American Journal of Pathology. Oct, 2011 | Pubmed ID: 21819957 Nuclear Factor Kappa B (NFkB) Pathway Associated Biomarkers in AIDS Defining Malignancies International Journal of Cancer. Journal International Du Cancer. Jul, 2011 | Pubmed ID: 21792887 Ribosomal Protein S6 Interacts with the Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus Journal of Virology. Sep, 2011 | Pubmed ID: 21734034 Tumor Suppressor Genes FHIT and WWOX Are Deleted in Primary Effusion Lymphoma (PEL) Cell Lines Blood. Aug, 2011 | Pubmed ID: 21685375 Pilot Study of Oral Valganciclovir Therapy in Patients with Classic Kaposi Sarcoma The Journal of Infectious Diseases. Apr, 2011 | Pubmed ID: 21450998 Interferon-γ Production by Neutrophils During Bacterial Pneumonia in Mice American Journal of Respiratory and Critical Care Medicine. May, 2011 | Pubmed ID: 21169470 The Flu Vaccine in Cancer Patients: Insights from Other Immune-suppressed Populations Oncology (Williston Park, N.Y.). Nov, 2010 | Pubmed ID: 21141701 An Appraisal of Non-AIDS-defining Cancers: Comment on "Spectrum of Cancer Risk Late After AIDS Onset in the United States" Archives of Internal Medicine. Aug, 2010 | Pubmed ID: 20696959 The Viral Latency-associated Nuclear Antigen Augments the B-cell Response to Antigen in Vivo Journal of Virology. Oct, 2010 | Pubmed ID: 20686032 Efficiency Clustering for Low-density Microarrays and Its Application to QPCR BMC Bioinformatics. 2010 | Pubmed ID: 20646303 Genome-wide Real-time PCR for West Nile Virus Reduces the False-negative Rate and Facilitates New Strain Discovery Journal of Virological Methods. Oct, 2010 | Pubmed ID: 20637239 Dual Inhibition of PI3K and MTOR Inhibits Autocrine and Paracrine Proliferative Loops in PI3K/Akt/mTOR-addicted Lymphomas Blood. Jun, 2010 | Pubmed ID: 20299510 Distinct P53, P53:LANA, and LANA Complexes in Kaposi's Sarcoma--associated Herpesvirus Lymphomas Journal of Virology. Apr, 2010 | Pubmed ID: 20130056 Molecular and Clinical Assessment in the Treatment of AIDS Kaposi Sarcoma with Valproic Acid Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Dec, 2009 | Pubmed ID: 19911999 Maribavir Inhibits Epstein-barr Virus Transcription in Addition to Viral DNA Replication Journal of Virology. Dec, 2009 | Pubmed ID: 19759127 General and Target-specific RNA Binding Properties of Epstein-Barr Virus SM Posttranscriptional Regulatory Protein Journal of Virology. Nov, 2009 | Pubmed ID: 19726500 Disruption of LANA in Rhesus Rhadinovirus Generates a Highly Lytic Recombinant Virus Journal of Virology. Oct, 2009 | Pubmed ID: 19587030 Toll-like Receptor Signaling Controls Reactivation of KSHV from Latency Proceedings of the National Academy of Sciences of the United States of America. Jul, 2009 | Pubmed ID: 19564611 Pre-micro RNA Signatures Delineate Stages of Endothelial Cell Transformation in Kaposi Sarcoma PLoS Pathogens. Apr, 2009 | Pubmed ID: 19381257 Tumor Suppressor MicroRNAs Are Underrepresented in Primary Effusion Lymphoma and Kaposi Sarcoma Blood. Jun, 2009 | Pubmed ID: 19252139 Burkitt Lymphoma in Brazil is Characterized by Geographically Distinct Clinicopathologic Features American Journal of Clinical Pathology. Dec, 2008 | Pubmed ID: 19019773 Multiple Pathways for Epstein-Barr Virus Episome Loss from Nasopharyngeal Carcinoma International Journal of Cancer. Journal International Du Cancer. Nov, 2008 | Pubmed ID: 18688856 EBV MicroRNAs in Primary Lymphomas and Targeting of CXCL-11 by Ebv-mir-BHRF1-3 Cancer Research. Mar, 2008 | Pubmed ID: 18316607 More on HIV-associated Kaposi's Sarcoma The New England Journal of Medicine. Jan, 2008 | Pubmed ID: 18234764 Gene Alteration and Precursor and Mature MicroRNA Transcription Changes Contribute to the MiRNA Signature of Primary Effusion Lymphoma Blood. Feb, 2008 | Pubmed ID: 18079361 Liposomal Daunorubicin As Treatment for Kaposi's Sarcoma International Journal of Nanomedicine. 2007 | Pubmed ID: 18019828 AIDS Related Malignancies in Brazil Current Opinion in Oncology. Sep, 2007 | Pubmed ID: 17762574 Targeted Therapy for Kaposi's Sarcoma and Kaposi's Sarcoma-associated Herpesvirus Current Opinion in Oncology. Sep, 2007 | Pubmed ID: 17762570 Development of a Fluorescence-based Assay to Screen Antiviral Drugs Against Kaposi's Sarcoma Associated Herpesvirus Molecular Cancer Therapeutics. Aug, 2007 | Pubmed ID: 17699731 KSHV-associated Disease in the AIDS Patient Cancer Treatment and Research. 2007 | Pubmed ID: 17672039 In Vivo-restricted and Reversible Malignancy Induced by Human Herpesvirus-8 KSHV: a Cell and Animal Model of Virally Induced Kaposi's Sarcoma Cancer Cell. Mar, 2007 | Pubmed ID: 17349582 Functional P53 Signaling in Kaposi's Sarcoma-associated Herpesvirus Lymphomas: Implications for Therapy Journal of Virology. Feb, 2007 | Pubmed ID: 17121789 Rapamycin is Efficacious Against Primary Effusion Lymphoma (PEL) Cell Lines in Vivo by Inhibiting Autocrine Signaling Blood. Mar, 2007 | Pubmed ID: 17082322 Reactivation of Kaposi's Sarcoma-associated Herpesvirus by Natural Products from Kaposi's Sarcoma Endemic Regions International Journal of Cancer. Journal International Du Cancer. Jan, 2007 | Pubmed ID: 17066452 Baboon Model for West Nile Virus Infection and Vaccine Evaluation Virology. Nov, 2006 | Pubmed ID: 16904151 Long-term-infected Telomerase-immortalized Endothelial Cells: a Model for Kaposi's Sarcoma-associated Herpesvirus Latency in Vitro and in Vivo Journal of Virology. May, 2006 | Pubmed ID: 16641275 Promoter Switching Allows Simultaneous Transcription of LANA and K14/vGPCR of Kaposi's Sarcoma-associated Herpesvirus Virology. Jun, 2006 | Pubmed ID: 16616289 Immortalization of Primary Endothelial Cells by the K1 Protein of Kaposi's Sarcoma-associated Herpesvirus Cancer Research. Apr, 2006 | Pubmed ID: 16585191 A Naturally Occurring Fatal Case of Herpesvirus Papio 2 Pneumonia in an Infant Baboon (Papio Hamadryas Anubis) Journal of the American Association for Laboratory Animal Science : JAALAS. Jan, 2006 | Pubmed ID: 16539338 The Latency-associated Nuclear Antigen of Kaposi Sarcoma-associated Herpesvirus Induces B Cell Hyperplasia and Lymphoma The Journal of Clinical Investigation. Mar, 2006 | Pubmed ID: 16498502 Faster Quantitative Real-time PCR Protocols May Lose Sensitivity and Show Increased Variability Nucleic Acids Research. 2005 | Pubmed ID: 16314296 Role of Notch Signal Transduction in Kaposi's Sarcoma-associated Herpesvirus Gene Expression Journal of Virology. Nov, 2005 | Pubmed ID: 16254371 Methylene Blue Photoinactivation Abolishes West Nile Virus Infectivity in Vivo Antiviral Research. Nov, 2005 | Pubmed ID: 16118025 Whole-genome Transcription Profiling of Rhesus Monkey Rhadinovirus Journal of Virology. Jul, 2005 | Pubmed ID: 15956606 Kaposi's Sarcoma in the Era of HAART-an Update on Mechanisms, Diagnostics and Treatment AIDS Reviews. Jan-Mar, 2005 | Pubmed ID: 15875661 Azidothymidine Inhibits NF-kappaB and Induces Epstein-Barr Virus Gene Expression in Burkitt Lymphoma Blood. Jul, 2005 | Pubmed ID: 15790788 Enhanced Cytotoxicity Without Internuclear Spread of Adenovirus Upon Cell Fusion by Measles Virus Glycoproteins Journal of Virology. Feb, 2005 | Pubmed ID: 15650215 Real-time Quantitative PCR Analysis of Viral Transcription Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 15507725 De Novo Generation of CD4 T Cells Against Viruses Present in the Host During Immune Reconstitution Blood. Mar, 2005 | Pubmed ID: 15479725 The Tumor Microenvironment Controls Primary Effusion Lymphoma Growth in Vivo Cancer Research. Jul, 2004 | Pubmed ID: 15256448 Methylene Blue Photoinactivation of RNA Viruses Antiviral Research. Mar, 2004 | Pubmed ID: 15168794 Comparison of the Rta/Orf50 Transactivator Proteins of Gamma-2-herpesviruses Journal of Virology. May, 2004 | Pubmed ID: 15113928 SYBR Green-based Real-time Quantitative PCR Assay for Detection of West Nile Virus Circumvents False-negative Results Due to Strain Variability Journal of Clinical Microbiology. Apr, 2004 | Pubmed ID: 15070997 Regulation and Autoregulation of the Promoter for the Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14742422 Novel Kaposi's Sarcoma-associated Herpesvirus Homolog in Baboons Journal of Virology. Jul, 2003 | Pubmed ID: 12829855 Viral Latent Proteins As Targets for Kaposi's Sarcoma and Kaposi's Sarcoma-associated Herpesvirus (KSHV/HHV-8) Induced Lymphoma Current Drug Targets. Infectious Disorders. Jun, 2003 | Pubmed ID: 12769790 Transcription Profile of Kaposi's Sarcoma-associated Herpesvirus in Primary Kaposi's Sarcoma Lesions As Determined by Real-time PCR Arrays Cancer Research. May, 2003 | Pubmed ID: 12727810 Tissue Specificity of the Kaposi's Sarcoma-associated Herpesvirus Latent Nuclear Antigen (LANA/orf73) Promoter in Transgenic Mice Journal of Virology. Nov, 2002 | Pubmed ID: 12368345 Charting Latency Transcripts in Kaposi's Sarcoma-associated Herpesvirus by Whole-genome Real-time Quantitative PCR Journal of Virology. Jun, 2002 | Pubmed ID: 12021355 Profiling of Pre-micro RNAs and microRNAs using Quantitative Real-time PCR (qPCR) Arrays Pauline Chugh*1, Kristen Tamburro*1, Dirk P Dittmer1 1Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, Center for AIDS Research, University of North Carolina at Chapel Hill JoVE 2210 Biology
Profiling of Pre-micro RNAs and microRNAs using Quantitative Real-time PCR (qPCR) Arrays Pauline Chugh*1, Kristen Tamburro*1, Dirk P Dittmer1 1Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, Center for AIDS Research, University of North Carolina at Chapel Hill JoVE 2210 Biology
