Dirk Steinritz Bundeswehr Institute of Pharmacology and Toxicology Biography Publications Institution JoVE Articles Dirk Steinritz has not added a biography. If you are Dirk Steinritz and would like to personalize this page please email our Author Liaison for assistance. Publications Comparison of the Toxicity of Sulfur Mustard and Its Oxidation Products in Vitro Toxicology Letters. Mar, 2020 | Pubmed ID: 31863871 Validation of Automated Pipetting Systems for Cell Culture Seeding, Exposure and Bio-analytical Assays in Sulfur Mustard Toxicology Toxicology Letters. Mar, 2020 | Pubmed ID: 31809884 Effect of Sulfur Mustard on Melanogenesis in Vitro Toxicology Letters. Feb, 2020 | Pubmed ID: 31785464 Sulfur Mustard Alkylates Steroid Hormones and Impacts Hormone Function in Vitro Archives of Toxicology. Nov, 2019 | Pubmed ID: 31515601 Skin Sensitizing Effects of Sulfur Mustard and Other Alkylating Agents in Accordance to OECD Guidelines Toxicology Letters. Oct, 2019 | Pubmed ID: 31404593 Evaluation of Selective and Non-selective Cyclooxygenase Inhibitors on Sulfur Mustard-induced Pro-inflammatory Cytokine Formation in Normal Human Epidermal Keratinocytes Toxicology Letters. Sep, 2019 | Pubmed ID: 31048000 Validation of the CULTEX® Radial Flow System for the Assessment of the Acute Inhalation Toxicity of Airborne Particles Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2019 | Pubmed ID: 30890356 A Wearable Origami-like Paper-based Electrochemical Biosensor for Sulfur Mustard Detection Biosensors & Bioelectronics. Mar, 2019 | Pubmed ID: 30682684 A Novel Exposure System Generating Nebulized Aerosol of Sulfur Mustard in Comparison to the Standard Submerse Exposure Chemico-biological Interactions. Jan, 2019 | Pubmed ID: 30502332 Necrosulfonamide - Unexpected Effect in the Course of a Sulfur Mustard Intoxication Chemico-biological Interactions. Jan, 2019 | Pubmed ID: 30391637 A Mass Spectrometric Platform for the Quantitation of Sulfur Mustard-induced Nucleic Acid Adducts As Mechanistically Relevant Biomarkers of Exposure Archives of Toxicology. 01, 2019 | Pubmed ID: 30324314 Role of Chemosensory TRP Channels in Lung Cancer Pharmaceuticals (Basel, Switzerland). Sep, 2018 | Pubmed ID: 30248976 Transient Receptor Potential Channel A1 (TRPA1) Regulates Sulfur Mustard-Induced Expression of Heat Shock 70 KDa Protein 6 () In Vitro Cells. Aug, 2018 | Pubmed ID: 30200301 TRPs in Tox: Involvement of Transient Receptor Potential-Channels in Chemical-Induced Organ Toxicity-A Structured Review Cells. Aug, 2018 | Pubmed ID: 30087301 Paper-based Electrochemical Sensor for On-site Detection of the Sulphur Mustard Environmental Science and Pollution Research International. Jun, 2018 | Pubmed ID: 29934830 TRPA1 Channels: Expression in Non-neuronal Murine Lung Tissues and Dispensability for Hyperoxia-induced Alveolar Epithelial Hyperplasia Pflugers Archiv : European Journal of Physiology. 08, 2018 | Pubmed ID: 29754249 Cytostatic Resistance Profile of the Sulfur Mustard Resistant Keratinocyte Cell Line HaCaT/SM Toxicology Letters. Sep, 2018 | Pubmed ID: 29551593 Mobilization of Human Mesenchymal Stem Cells Through Different Cytokines and Growth Factors After Their Immobilization by Sulfur Mustard Toxicology Letters. Sep, 2018 | Pubmed ID: 29426001 Accidental Sulfur Mustard Exposure: A Case Report Toxicology Letters. Sep, 2018 | Pubmed ID: 29191789 Sulfur Mustard Resistant Keratinocytes Obtained Elevated Glutathione Levels and Other Changes in the Antioxidative Defense Mechanism Toxicology Letters. Sep, 2018 | Pubmed ID: 29183814 Sulfur Mustard-induced Epigenetic Modifications over Time - a Pilot Study Toxicology Letters. Sep, 2018 | Pubmed ID: 29155286 Immediate Responses of the Cockroach Blaptica Dubia After the Exposure to Sulfur Mustard Archives of Toxicology. Jan, 2018 | Pubmed ID: 28932886 Zinc Chloride-induced TRPA1 Activation Does Not Contribute to Toxicity in Vitro Toxicology Letters. Sep, 2018 | Pubmed ID: 28919489 Anti-apoptotic and Moderate Anti-inflammatory Effects of Berberine in Sulfur Mustard Exposed Keratinocytes Toxicology Letters. Sep, 2018 | Pubmed ID: 28916288 Effects of Anti-inflammatory Compounds on Sulfur Mustard Injured Cells: Recommendations and Caveats Suggested by in Vitro Cell Culture Models Toxicology Letters. Sep, 2018 | Pubmed ID: 28916287 Alteration of MiRNA Expression in a Sulfur Mustard Resistant Cell Line Toxicology Letters. Sep, 2018 | Pubmed ID: 28823541 Effects of Sulfur Mustard on Mesenchymal Stem Cells Toxicology Letters. Sep, 2018 | Pubmed ID: 28818580 S - and N-alkylating Agents Diminish the Fluorescence of Fluorescent Dye-stained DNA Chemico-biological Interactions. Jan, 2017 | Pubmed ID: 27923644 N-Acetyl-L-cysteine Inhibits Sulfur Mustard-induced and TRPA1-dependent Calcium Influx Archives of Toxicology. May, 2017 | Pubmed ID: 27738742 Editorial Toxicology Letters. Feb, 2016 | Pubmed ID: 26873068 Development of the Sulfur Mustard Resistant Keratinocyte Cell Line HaCaT/SM Toxicology Letters. Feb, 2016 | Pubmed ID: 26463895 Alteration of MiRNA Expression in Early Endothelial Cells After Exposure with Sub-lethal Sulfur Mustard Concentrations Toxicology Letters. Feb, 2016 | Pubmed ID: 26456178 Characterization of Sulfur Mustard Resistant Keratinocyte Cell Line HaCaT/SM Toxicology Letters. Feb, 2016 | Pubmed ID: 26456177 Epigenetic Modulations in Early Endothelial Cells and DNA Hypermethylation in Human Skin After Sulfur Mustard Exposure Toxicology Letters. Feb, 2016 | Pubmed ID: 26392148 Immunochemical Analysis of Poly(ADP-ribosyl)ation in HaCaT Keratinocytes Induced by the Mono-alkylating Agent 2-chloroethyl Ethyl Sulfide (CEES): Impact of Experimental Conditions Toxicology Letters. Feb, 2016 | Pubmed ID: 26383632 Sulfur and Nitrogen Mustards Induce Characteristic Poly(ADP-ribosyl)ation Responses in HaCaT Keratinocytes with Distinctive Cellular Consequences Toxicology Letters. Feb, 2016 | Pubmed ID: 26383629 Upregulation of MiR-203 and MiR-210 Affect Growth and Differentiation of Keratinocytes After Exposure to Sulfur Mustard in Normoxia and Hypoxia Toxicology Letters. Feb, 2016 | Pubmed ID: 26383628 Protective Effects of the Thiol Compounds GSH and NAC Against Sulfur Mustard Toxicity in a Human Keratinocyte Cell Line Toxicology Letters. Feb, 2016 | Pubmed ID: 26361990 Optimization of the CULTEX(®) Radial Flow System for in Vitro Investigation of Lung Damaging Agents Toxicology Letters. Feb, 2016 | Pubmed ID: 26358518 Medical Documentation, Bioanalytical Evidence of an Accidental Human Exposure to Sulfur Mustard and General Therapy Recommendations Toxicology Letters. Feb, 2016 | Pubmed ID: 26321678 Repetitive Obidoxime Treatment Induced Increase of Red Blood Cell Acetylcholinesterase Activity Even in a Late Phase of a Severe Methamidophos Poisoning: A Case Report Toxicology Letters. Feb, 2016 | Pubmed ID: 26200596 Impairment of Hypoxia-induced HIF-1α Signaling in Keratinocytes and Fibroblasts by Sulfur Mustard is Counteracted by a Selective PHD-2 Inhibitor Archives of Toxicology. Jun, 2015 | Pubmed ID: 26082309 Activation of the Chemosensing Transient Receptor Potential Channel A1 (TRPA1) by Alkylating Agents Archives of Toxicology. Nov, 2014 | Pubmed ID: 25395009 Development of a Co-culture of Keratinocytes and Immune Cells for in Vitro Investigation of Cutaneous Sulfur Mustard Toxicity Chemico-biological Interactions. Sep, 2014 | Pubmed ID: 25256379 Chlorambucil (nitrogen Mustard) Induced Impairment of Early Vascular Endothelial Cell Migration - Effects of α-linolenic Acid and N-acetylcysteine Chemico-biological Interactions. Aug, 2014 | Pubmed ID: 24892517 Detection of Key Enzymes, Free Radical Reaction Products and Activated Signaling Molecules As Biomarkers of Cell Damage Induced by Benzo[a]pyrene in Human Keratinocytes Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2014 | Pubmed ID: 24685774 Wnt5a/β-catenin Signaling Drives Calcium-induced Differentiation of Human Primary Keratinocytes The Journal of Investigative Dermatology. Aug, 2014 | Pubmed ID: 24658506 Functional Expression of the Transient Receptor Potential Channel TRPA1, a Sensor for Toxic Lung Inhalants, in Pulmonary Epithelial Cells Chemico-biological Interactions. Aug, 2013 | Pubmed ID: 23994502 Influence of Organophosphate Poisoning on Human Dendritic Cells Chemico-biological Interactions. Dec, 2013 | Pubmed ID: 23994500 Mesenchymal Stem Cells Are Highly Resistant to Sulfur Mustard Chemico-biological Interactions. Dec, 2013 | Pubmed ID: 23933411 Modified Immunoslotblot Assay to Detect Hemi and Sulfur Mustard DNA Adducts Chemico-biological Interactions. Dec, 2013 | Pubmed ID: 23933409 Sulfur Mustard Induced Nuclear Translocation of Glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) Chemico-biological Interactions. Dec, 2013 | Pubmed ID: 23827652 Silibinin As a Potential Therapeutic for Sulfur Mustard Injuries Chemico-biological Interactions. Dec, 2013 | Pubmed ID: 23810508 Use of the Cultex® Radial Flow System As an in Vitro Exposure Method to Assess Acute Pulmonary Toxicity of Fine Dusts and Nanoparticles with Special Focus on the Intra- and Inter-laboratory Reproducibility Chemico-biological Interactions. Dec, 2013 | Pubmed ID: 23669118 Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential As "sweet Spots" for Targeted Therapies Reviews of Physiology, Biochemistry and Pharmacology. 2013 | Pubmed ID: 23532495 STIMulating Stress Fibers in Endothelial Cells Science Signaling. 2013 | Pubmed ID: 23512987 Atropine Maintenance Dosage in Patients with Severe Organophosphate Pesticide Poisoning Toxicology Letters. Sep, 2011 | Pubmed ID: 21771644 Sulfur Mustard Induces Differentiation in Human Primary Keratinocytes: Opposite Roles of P38 and ERK1/2 MAPK Toxicology Letters. Jul, 2011 | Pubmed ID: 21524694 High-throughput Analysis of DNA Interstrand Crosslinks in Human Peripheral Blood Mononuclear Cells by Automated Reverse FADU Assay Toxicology. Feb, 2011 | Pubmed ID: 21115096 Effect of N-acetyl Cysteine and Alpha-linolenic Acid on Sulfur Mustard Caused Impairment of in Vitro Endothelial Tube Formation Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2010 | Pubmed ID: 20833707 Nitrogen Mustard (Chlorambucil) Has a Negative Influence on Early Vascular Development Toxicology. Sep, 2009 | Pubmed ID: 18930110 Red Blood Cell Acetylcholinesterase and Plasma Butyrylcholinesterase Status: Important Indicators for the Treatment of Patients Poisoned by Organophosphorus Compounds Arhiv Za Higijenu Rada I Toksikologiju. Sep, 2007 | Pubmed ID: 17913691 Assessment of Alterations in Barrier Functionality and Induction of Proinflammatory and Cytotoxic Effects After Sulfur Mustard Exposure of an in Vitro Coculture Model of the Human Alveolo-capillary Barrier Inhalation Toxicology. Jun, 2007 | Pubmed ID: 17510838 Beta3-adrenergic ENOS Stimulation in Left Ventricular Murine Myocardium Canadian Journal of Physiology and Pharmacology. Oct, 2006 | Pubmed ID: 17328145 [On the Function of Beta3-adrenoceptors in the Human Heart: Signal Transduction, Inotropic Effect and Therapeutic Prospects] Wiener Medizinische Wochenschrift (1946). Aug, 2006 | Pubmed ID: 17041771 Evaluation of Tetrahydrobiopterin (BH4) As a Potential Therapeutic Agent to Treat Erectile Dysfunction Asian Journal of Andrology. Mar, 2006 | Pubmed ID: 16491266 ENOS Translocation but Not ENOS Phosphorylation is Dependent on Intracellular Ca2+ in Human Atrial Myocardium American Journal of Physiology. Cell Physiology. May, 2006 | Pubmed ID: 16338973 Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface Amelie Tsoutsoulopoulos1, Katrin Gohlsch2, Niklas Möhle3, Andreas Breit2, Sebastian Hoffmann5, Olaf Krischenowski3,4, Harald Mückter2, Thomas Gudermann2, Horst Thiermann1, Michaela Aufderheide3,4, Dirk Steinritz1,2 1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services JoVE 60572 Medicine Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals Dirk Steinritz1,2, Annette Schmidt1,3, Frank Balszuweit1, Horst Thiermann1, Marwa Ibrahim3, Birgit Bölck3, Wilhelm Bloch3 1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, 3Department of Molecular and Cellular Sports Medicine, German Sports University Cologne JoVE 52768 Developmental Biology
Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface Amelie Tsoutsoulopoulos1, Katrin Gohlsch2, Niklas Möhle3, Andreas Breit2, Sebastian Hoffmann5, Olaf Krischenowski3,4, Harald Mückter2, Thomas Gudermann2, Horst Thiermann1, Michaela Aufderheide3,4, Dirk Steinritz1,2 1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services JoVE 60572 Medicine
Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals Dirk Steinritz1,2, Annette Schmidt1,3, Frank Balszuweit1, Horst Thiermann1, Marwa Ibrahim3, Birgit Bölck3, Wilhelm Bloch3 1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, 3Department of Molecular and Cellular Sports Medicine, German Sports University Cologne JoVE 52768 Developmental Biology
