Erik Serrao Department of Cancer Immunology and AIDS Dana-Farber Cancer Institute Biography Publications Institution JoVE Articles Erik Serrao has not added a biography. If you are Erik Serrao and would like to personalize this page please email our Author Liaison for assistance. Publications The Competitive Interplay Between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 During the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency ACS Chemical Biology. Mar, 2016 | Pubmed ID: 26910179 A Critical Role for Alternative Polyadenylation Factor CPSF6 in Targeting HIV-1 Integration to Transcriptionally Active Chromatin Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26858452 Sites of Retroviral DNA Integration: From Basic Research to Clinical Applications Critical Reviews in Biochemistry and Molecular Biology. Jan-Feb, 2016 | Pubmed ID: 26508664 Structural Basis for Retroviral Integration into Nucleosomes Nature. Jul, 2015 | Pubmed ID: 26061770 Key Determinants of Target DNA Recognition by Retroviral Intasomes Retrovirology. 2015 | Pubmed ID: 25924943 Host and Viral Determinants for MxB Restriction of HIV-1 Infection Retrovirology. 2014 | Pubmed ID: 25348155 Molecular Mechanisms of Retroviral Integration Site Selection Nucleic Acids Research. 2014 | Pubmed ID: 25147212 Design and Discovery of Flavonoid-based HIV-1 Integrase Inhibitors Targeting Both the Active Site and the Interaction with LEDGF/p75 Bioorganic & Medicinal Chemistry. Jun, 2014 | Pubmed ID: 24794743 Integrase Residues That Determine Nucleotide Preferences at Sites of HIV-1 Integration: Implications for the Mechanism of Target DNA Binding Nucleic Acids Research. Apr, 2014 | Pubmed ID: 24520116 Alteration of Select Gene Expression Patterns in Individuals Infected with HIV-1 Journal of Medical Virology. Apr, 2014 | Pubmed ID: 24482297 Biochemical Characterization of Novel Retroviral Integrase Proteins PloS One. 2013 | Pubmed ID: 24124581 Discovery of a Novel 5-carbonyl-1H-imidazole-4-carboxamide Class of Inhibitors of the HIV-1 Integrase-LEDGF/p75 Interaction Bioorganic & Medicinal Chemistry. Oct, 2013 | Pubmed ID: 23985689 Fragment-based Discovery of 8-hydroxyquinoline Inhibitors of the HIV-1 Integrase-lens Epithelium-derived Growth Factor/p75 (IN-LEDGF/p75) Interaction Journal of Medicinal Chemistry. Mar, 2013 | Pubmed ID: 23445471 1 HIV インテグラーゼ ダイマー化インターフェイスの対称領域はウイルスの複製に不可欠です。 PloS One. 2012 | Pubmed ID: 23028829 HIV-1 Integrase Inhibitors: 2007-2008 Update Medicinal Research Reviews. Nov, 2010 | Pubmed ID: 20135632 Raltegravir, Elvitegravir, and Metoogravir: the Birth of "me-too" HIV-1 Integrase Inhibitors Retrovirology. 2009 | Pubmed ID: 19265512 レトロウイルス統合サイトの増幅、次世代シーケンシング、およびゲノムDNAのマッピング Erik Serrao1, Peter Cherepanov2, Alan N. Engelman1 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 2Chromatin Structure and Mobile DNA, The Francis Crick Institute Biology
レトロウイルス統合サイトの増幅、次世代シーケンシング、およびゲノムDNAのマッピング Erik Serrao1, Peter Cherepanov2, Alan N. Engelman1 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 2Chromatin Structure and Mobile DNA, The Francis Crick Institute Biology