Florin M. Selaru Division of Gastroenterology and Hepatology, Department of Medicine Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Florin M. Selaru has not added a biography. If you are Florin M. Selaru and would like to personalize this page please email our Author Liaison for assistance. Publications Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers Gastroenterology. Apr, 2016 | Pubmed ID: 26764183 The Genome-wide Gene Expression Profiling to Predict Competitive Endogenous RNA Network in Hepatocellular Cancer Genomics Data. Jun, 2015 | Pubmed ID: 26484188 MicroRNA-224 Induces G1/S Checkpoint Release in Liver Cancer Journal of Clinical Medicine. 2015 | Pubmed ID: 26343737 Pseudogene INTS6P1 Regulates Its Cognate Gene INTS6 Through Competitive Binding of MiR-17-5p in Hepatocellular Carcinoma Oncotarget. Mar, 2015 | Pubmed ID: 25686840 MicroRNAs in the Biology and Diagnosis of Cholangiocarcinoma Seminars in Liver Disease. Feb, 2015 | Pubmed ID: 25632935 Reply: To PMID 24497320 Hepatology (Baltimore, Md.). Jul, 2015 | Pubmed ID: 25308572 Reply: To PMID 21858175 Hepatology (Baltimore, Md.). Mar, 2015 | Pubmed ID: 25048815 Stimuli-responsive Theragrippers for Chemomechanical Controlled Release Angewandte Chemie (International Ed. in English). Jul, 2014 | Pubmed ID: 24634136 Human Bile Contains MicroRNA-laden Extracellular Vesicles That Can Be Used for Cholangiocarcinoma Diagnosis Hepatology (Baltimore, Md.). Sep, 2014 | Pubmed ID: 24497320 Exome Sequencing Identifies Frequent Inactivating Mutations in BAP1, ARID1A and PBRM1 in Intrahepatic Cholangiocarcinomas Nature Genetics. Dec, 2013 | Pubmed ID: 24185509 MiRNA-Based Therapeutic Strategies Current Anesthesiology Reports. Mar, 2013 | Pubmed ID: 23524956 Connecting the Dots from Fatty Acids to Nonalcoholic Steatohepatitis: Epigenetics in the Spotlight Hepatology (Baltimore, Md.). Aug, 2013 | Pubmed ID: 23460470 Biologic Tissue Sampling with Untethered Microgrippers Gastroenterology. Apr, 2013 | Pubmed ID: 23399954 MicroRNA-224 Negatively Regulates P21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease Inflammatory Bowel Diseases. Mar, 2013 | Pubmed ID: 23399735 Biopsy with Thermally-responsive Untethered Microtools Advanced Materials (Deerfield Beach, Fla.). Jan, 2013 | Pubmed ID: 23047708 Silencing of MiR-370 in Human Cholangiocarcinoma by Allelic Loss and Interleukin-6 Induced Maternal to Paternal Epigenotype Switch PloS One. 2012 | Pubmed ID: 23110045 Coordinated Effects of MicroRNA-494 Induce Gâ‚‚/M Arrest in Human Cholangiocarcinoma Cell Cycle (Georgetown, Tex.). Jul, 2012 | Pubmed ID: 22785131 MicroRNA-21 Inhibits Serpini1, a Gene with Novel Tumour Suppressive Effects in Gastric Cancer Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. Mar, 2012 | Pubmed ID: 22464652 Methylation of the CpG Sites Only on the Sense Strand of the APC Gene is Specific for Hepatocellular Carcinoma PloS One. 2011 | Pubmed ID: 22073196 MicroRNA Down-regulated in Human Cholangiocarcinoma Control Cell Cycle Through Multiple Targets Involved in the G1/S Checkpoint Hepatology (Baltimore, Md.). Dec, 2011 | Pubmed ID: 21809359 Novel Candidate Colorectal Cancer Biomarkers Identified by Methylation Microarray-based Scanning Endocrine-related Cancer. Aug, 2011 | Pubmed ID: 21636702 Dynamic Changes in the Expression of MicroRNA-31 During Inflammatory Bowel Disease-associated Neoplastic Transformation Inflammatory Bowel Diseases. Jan, 2011 | Pubmed ID: 20848542 Polo-like Kinase 1 Regulates Cell Proliferation and is Targeted by MiR-593* in Esophageal Cancer International Journal of Cancer. Journal International Du Cancer. Dec, 2010 | Pubmed ID: 21170987 Enzymatically Triggered Actuation of Miniaturized Tools Journal of the American Chemical Society. Nov, 2010 | Pubmed ID: 20849106 Silencing of Claudin-11 is Associated with Increased Invasiveness of Gastric Cancer Cells PloS One. 2009 | Pubmed ID: 19956721 Epigenetic Events in Gastrointestinal Cancer The American Journal of Gastroenterology. Aug, 2009 | Pubmed ID: 19661933 A Multicenter, Double-blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus Cancer Research. May, 2009 | Pubmed ID: 19435894 The MiR-106b-25 Polycistron, Activated by Genomic Amplification, Functions As an Oncogene by Suppressing P21 and Bim Gastroenterology. May, 2009 | Pubmed ID: 19422085 MicroRNA-21 is Overexpressed in Human Cholangiocarcinoma and Regulates Programmed Cell Death 4 and Tissue Inhibitor of Metalloproteinase 3 Hepatology (Baltimore, Md.). May, 2009 | Pubmed ID: 19296468 Gastrointestinal Stromal Tumor Causing Obscure-occult Gastrointestinal Bleeding Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Apr, 2009 | Pubmed ID: 19111948 Promoter Hypermethylation of CDH13 is a Common, Early Event in Human Esophageal Adenocarcinogenesis and Correlates with Clinical Risk Factors International Journal of Cancer. Journal International Du Cancer. Nov, 2008 | Pubmed ID: 18729198 Generation of Small 32P-labeled Peptides As a Potential Approach to Colorectal Cancer Therapy PloS One. 2008 | Pubmed ID: 18575578 Beyond Field Effect: Analysis of Shrunken Centroids in Normal Esophageal Epithelia Detects Concomitant Esophageal Adenocarcinoma Bioinformatics and Biology Insights. 2007 | Pubmed ID: 18425214 Electronic Clinical Challenges and Images in GI. Fibrolamellar Carcinoma Gastroenterology. Nov, 2007 | Pubmed ID: 17983790 The Molecular Signature of Normal Squamous Esophageal Epithelium Identifies the Presence of a Field Effect and Can Discriminate Between Patients with Barrett's Esophagus and Patients with Barrett's-associated Adenocarcinoma Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Sep, 2005 | Pubmed ID: 16172218 Prediction of Survival in Patients with Esophageal Carcinoma Using Artificial Neural Networks Cancer. Apr, 2005 | Pubmed ID: 15751017 Esophagin and Proliferating Cell Nuclear Antigen (PCNA) Are Biomarkers of Human Esophageal Neoplastic Progression International Journal of Cancer. Sep, 2004 | Pubmed ID: 15221970 Identification of Genes Uniquely Involved in Frequent Microsatellite Instability Colon Carcinogenesis by Expression Profiling Combined with Epigenetic Scanning Cancer Research. Apr, 2004 | Pubmed ID: 15059896 An Unsupervised Approach to Identify Molecular Phenotypic Components Influencing Breast Cancer Features Cancer Research. Mar, 2004 | Pubmed ID: 14996713 Loss of Heterozygosity and Mutational Analyses of the ACTRII Gene Locus in Human Colorectal Tumors Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2003 | Pubmed ID: 14691305 The Impact of Microsatellite Instability on the Molecular Phenotype of Colorectal Tumors Cancer Research. Aug, 2003 | Pubmed ID: 12907634 An LOH and Mutational Investigation of the ST7 Gene Locus in Human Esophageal Carcinoma Oncogene. Jan, 2003 | Pubmed ID: 12545169 Aberrant Methylation of the HPP1 Gene in Ulcerative Colitis-associated Colorectal Carcinoma Cancer Research. Dec, 2002 | Pubmed ID: 12460892 Application of CDNA Microarrays to Generate a Molecular Taxonomy Capable of Distinguishing Between Colon Cancer and Normal Colon Oncogene. Jul, 2002 | Pubmed ID: 12101425 Instabilotyping Reveals Unique Mutational Spectra in Microsatellite-unstable Gastric Cancers Cancer Research. Jul, 2002 | Pubmed ID: 12097267 Artificial Neural Networks and Gene Filtering Distinguish Between Global Gene Expression Profiles of Barrett's Esophagus and Esophageal Cancer Cancer Research. Jun, 2002 | Pubmed ID: 12067993 Artificial Neural Networks Distinguish Among Subtypes of Neoplastic Colorectal Lesions Gastroenterology. Mar, 2002 | Pubmed ID: 11874992 Hypermethylation of the P14(ARF) Gene in Ulcerative Colitis-associated Colorectal Carcinogenesis Cancer Research. Feb, 2002 | Pubmed ID: 11861396 Isolation and Profiling of MicroRNA-containing Exosomes from Human Bile Ling Li1, Klaus B. Piontek1, Vivek Kumbhari1, Masaharu Ishida2, Florin M. Selaru1 1Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, 2Department of Surgery, Tohoku University JoVE 54036 Medicine
Isolation and Profiling of MicroRNA-containing Exosomes from Human Bile Ling Li1, Klaus B. Piontek1, Vivek Kumbhari1, Masaharu Ishida2, Florin M. Selaru1 1Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, 2Department of Surgery, Tohoku University JoVE 54036 Medicine
