Francois Paquet-Durand Institute for Ophthalmic Research University of Tübingen Biography Publications Institution JoVE Articles Francois Paquet-Durand has not added a biography. If you are Francois Paquet-Durand and would like to personalize this page please email our Author Liaison for assistance. Publications Targeted Ablation of the Pde6h Gene in Mice Reveals Cross-species Differences in Cone and Rod Phototransduction Protein Isoform Inventory The Journal of Biological Chemistry. Apr, 2015 | Pubmed ID: 25739440 Identification of a Common Non-apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration PloS One. 2014 | Pubmed ID: 25392995 Characterization of a Mouse Model with Complete RPE Loss and Its Use for RPE Cell Transplantation Investigative Ophthalmology & Visual Science. Aug, 2014 | Pubmed ID: 25103259 Expression of Poly(ADP-ribose) Glycohydrolase in Wild-type and PARG-110 Knock-out Retina Advances in Experimental Medicine and Biology. 2014 | Pubmed ID: 24664732 Inhibition of Mitochondrial Pyruvate Transport by Zaprinast Causes Massive Accumulation of Aspartate at the Expense of Glutamate in the Retina The Journal of Biological Chemistry. Dec, 2013 | Pubmed ID: 24187136 Retinitis Pigmentosa: Over-expression of Anti-ageing Protein Klotho in Degenerating Photoreceptors Journal of Neurochemistry. Dec, 2013 | Pubmed ID: 23796581 Testing for a Gap Junction-mediated Bystander Effect in Retinitis Pigmentosa: Secondary Cone Death is Not Altered by Deletion of Connexin36 from Cones PloS One. 2013 | Pubmed ID: 23468924 Calpain Mediated Ataxin-3 Cleavage in the Molecular Pathogenesis of Spinocerebellar Ataxia Type 3 (SCA3) Human Molecular Genetics. Oct, 2012 | Pubmed ID: 23100324 Light-driven Calcium Signals in Mouse Cone Photoreceptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2012 | Pubmed ID: 22593066 CGMP-Prkg1 Signaling and Pde5 Inhibition Shelter Cochlear Hair Cells and Hearing Function Nature Medicine. Feb, 2012 | Pubmed ID: 22270721 In Vivo Assessment of Rodent Retinal Structure Using Spectral Domain Optical Coherence Tomography Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183368 HDAC Inhibition Prevents Rd1 Mouse Photoreceptor Degeneration Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183322 Calpain and PARP Activation During Photoreceptor Cell Death in P23H and S334ter Rhodopsin Mutant Rats PloS One. 2011 | Pubmed ID: 21765948 A Key Role for Cyclic Nucleotide Gated (CNG) Channels in CGMP-related Retinitis Pigmentosa Human Molecular Genetics. Mar, 2011 | Pubmed ID: 21149284 PARP1 Gene Knock-out Increases Resistance to Retinal Degeneration Without Affecting Retinal Function PloS One. 2010 | Pubmed ID: 21124852 Photoreceptor Rescue and Toxicity Induced by Different Calpain Inhibitors Journal of Neurochemistry. Nov, 2010 | Pubmed ID: 20807308 Restoration of Cone Vision in the CNGA3-/- Mouse Model of Congenital Complete Lack of Cone Photoreceptor Function Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2010 | Pubmed ID: 20628362 CGMP-dependent Cone Photoreceptor Degeneration in the Cpfl1 Mouse Retina The Journal of Comparative Neurology. Sep, 2010 | Pubmed ID: 20593360 Spectral Domain Optical Coherence Tomography in Mouse Models of Retinal Degeneration Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19661229 Study of Gene-targeted Mouse Models of Splicing Factor Gene Prpf31 Implicated in Human Autosomal Dominant Retinitis Pigmentosa (RP) Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19578015 Cellular Phenotypes of Human Model Neurons (NT2) After Differentiation in Aggregate Culture Cell and Tissue Research. Jun, 2009 | Pubmed ID: 19377856 PKG Activity Causes Photoreceptor Cell Death in Two Retinitis Pigmentosa Models Journal of Neurochemistry. Feb, 2009 | Pubmed ID: 19187097 Photoreceptor Cell Death Mechanisms in Inherited Retinal Degeneration Molecular Neurobiology. Dec, 2008 | Pubmed ID: 18982459 Simulation of Stroke-related Damage in Cultured Human Nerve Cells ALTEX. 2007 | Pubmed ID: 19835047 Human Model Neurons in Studies of Brain Cell Damage and Neural Repair Current Molecular Medicine. Sep, 2007 | Pubmed ID: 17896991 Excessive Activation of Poly(ADP-ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2007 | Pubmed ID: 17881537 Calpain Activity in Retinal Degeneration Journal of Neuroscience Research. Mar, 2007 | Pubmed ID: 17171699 CNTF+BDNF Treatment and Neuroprotective Pathways in the Rd1 Mouse Retina Brain Research. Jan, 2007 | Pubmed ID: 17156753 Diltiazem Protects Human NT-2 Neurons Against Excitotoxic Damage in a Model of Simulated Ischemia Brain Research. Dec, 2006 | Pubmed ID: 17070504 Up-regulation and Increased Phosphorylation of Protein Kinase C (PKC) Delta, Mu and Theta in the Degenerating Rd1 Mouse Retina Molecular and Cellular Neurosciences. Apr, 2006 | Pubmed ID: 16503160 Calpain is Activated in Degenerating Photoreceptors in the Rd1 Mouse Journal of Neurochemistry. Feb, 2006 | Pubmed ID: 16405498 Differential Modification of Phosducin Protein in Degenerating Rd1 Retina is Associated with Constitutively Active Ca2+/calmodulin Kinase II in Rod Outer Segments Molecular & Cellular Proteomics : MCP. Feb, 2006 | Pubmed ID: 16253986 Hypoxic/ischaemic Cell Damage in Cultured Human NT-2 Neurons Brain Research. Jun, 2004 | Pubmed ID: 15140642 Turning Teratocarcinoma Cells into Neurons: Rapid Differentiation of NT-2 Cells in Floating Spheres Brain Research. Developmental Brain Research. May, 2003 | Pubmed ID: 12711367 Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina Manoj Kulkarni1,2, Timm Schubert1,3, Tom Baden1,2,3, Bernd Wissinger4,5, Thomas Euler1,2,3, Francois Paquet-Durand1 1Institute for Ophthalmic Research, University of Tübingen, 2Graduate School of Cellular & Molecular Neuroscience, University of Tübingen, 3Bernstein Centre for Computational Neuroscience, University of Tübingen, 4Molecular Genetics Laboratory, University of Tübingen, 5Centre for Ophthalmology, University of Tübingen JoVE 52588 Neuroscience
Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina Manoj Kulkarni1,2, Timm Schubert1,3, Tom Baden1,2,3, Bernd Wissinger4,5, Thomas Euler1,2,3, Francois Paquet-Durand1 1Institute for Ophthalmic Research, University of Tübingen, 2Graduate School of Cellular & Molecular Neuroscience, University of Tübingen, 3Bernstein Centre for Computational Neuroscience, University of Tübingen, 4Molecular Genetics Laboratory, University of Tübingen, 5Centre for Ophthalmology, University of Tübingen JoVE 52588 Neuroscience