Gary Splitter Pathobiological Sciences University of Wisconsin-Madison Biography Publications Institution JoVE Articles Gary Splitter has not added a biography. If you are Gary Splitter and would like to personalize this page please email our Author Liaison for assistance. Publications Brucella Melitensis Cyclic Di-GMP Phosphodiesterase BpdA Controls Expression of Flagellar Genes Journal of Bacteriology. Oct, 2011 | Pubmed ID: 21856843 Modulation of Microtubule Dynamics by a TIR Domain Protein from the Intracellular Pathogen Brucella Melitensis The Biochemical Journal. Oct, 2011 | Pubmed ID: 21692747 Biochemical and Functional Analysis of TIR Domain Containing Protein from Brucella Melitensis Biochemical and Biophysical Research Communications. Jun, 2010 | Pubmed ID: 20471373 Discordant Brucella Melitensis Antigens Yield Cognate CD8+ T Cells in Vivo Infection and Immunity. Jan, 2010 | Pubmed ID: 19884330 Brucella Melitensis, B. Neotomae and B. Ovis Elicit Common and Distinctive Macrophage Defense Transcriptional Responses Experimental Biology and Medicine (Maywood, N.J.). Dec, 2009 | Pubmed ID: 19934366 Brucella Regulators: Self-control in a Hostile Environment Trends in Microbiology. Aug, 2009 | Pubmed ID: 19660951 Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP The Journal of Biological Chemistry. Apr, 2009 | Pubmed ID: 19196716 Evaluation of Recombinant Invasive, Non-pathogenic Eschericia Coli As a Vaccine Vector Against the Intracellular Pathogen, Brucella Journal of Immune Based Therapies and Vaccines. 2009 | Pubmed ID: 19126207 TBK1 Does Not Play a Role in the Control of in Vitro Burkholderia Pseudomallei Growth Transactions of the Royal Society of Tropical Medicine and Hygiene. Dec, 2008 | Pubmed ID: 19121697 Genomic Island 2 of Brucella Melitensis is a Major Virulence Determinant: Functional Analyses of Genomic Islands Journal of Bacteriology. Sep, 2008 | Pubmed ID: 18641138 Putative Quorum-sensing Regulator BlxR of Brucella Melitensis Regulates Virulence Factors Including the Type IV Secretion System and Flagella Journal of Bacteriology. May, 2008 | Pubmed ID: 18310341 DNA Recognition Properties of the Cell-to-cell Movement Protein (MP) of Soybean Isolate of Mungbean Yellow Mosaic India Virus (MYMIV-Sb) Virus Research. Feb, 2008 | Pubmed ID: 17949843 Blue-light-activated Histidine Kinases: Two-component Sensors in Bacteria Science (New York, N.Y.). Aug, 2007 | Pubmed ID: 17717187 DNA Vaccine Construct Incorporating Intercellular Trafficking and Intracellular Targeting Motifs Effectively Primes and Induces Memory B- and T-cell Responses in Outbred Animals Clinical and Vaccine Immunology : CVI. Mar, 2007 | Pubmed ID: 17215335 Brucella: Functional Genomics and Host-pathogen Interactions Animal Health Research Reviews / Conference of Research Workers in Animal Diseases. Jun-Dec, 2006 | Pubmed ID: 17389050 CGHScan: Finding Variable Regions Using High-density Microarray Comparative Genomic Hybridization Data BMC Genomics. 2006 | Pubmed ID: 16638145 Attenuated Bioluminescent Brucella Melitensis Mutants GR019 (virB4), GR024 (galE), and GR026 (BMEI1090-BMEI1091) Confer Protection in Mice Infection and Immunity. May, 2006 | Pubmed ID: 16622231 Unraveling Brucella Genomics and Pathogenesis in Immunocompromised IRF-1-/- Mice American Journal of Reproductive Immunology (New York, N.Y. : 1989). Dec, 2005 | Pubmed ID: 16305661 Temporal Analysis of Pathogenic Events in Virulent and Avirulent Brucella Melitensis Infections Cellular Microbiology. Oct, 2005 | Pubmed ID: 16153245 Enhancement of Antigen Acquisition by Dendritic Cells and MHC Class II-restricted Epitope Presentation to CD4+ T Cells Using VP22 DNA Vaccine Vectors That Promote Intercellular Spreading Following Initial Transfection Journal of Leukocyte Biology. Aug, 2005 | Pubmed ID: 15857936 Nuclear and Mitochondrial Localization Signals Overlap Within Bovine Herpesvirus 1 Tegument Protein VP22 The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15705574 Bovine Herpesvirus VP22 Induces Apoptosis in Neuroblastoma Cells by Upregulating the Expression Ratio of Bax to Bcl-2 Human Gene Therapy. Jan, 2005 | Pubmed ID: 15703493 Isolation of Brucella Abortus Total RNA from B. Abortus-infected Murine RAW Macrophages Journal of Microbiological Methods. Mar, 2005 | Pubmed ID: 15649540 The Role of Integrase/recombinase XerD and Monofunctional Biosynthesis Peptidoglycan Transglycosylase Genes in the Pathogenicity of Brucella Abortus Infection in Vitro and in Vivo Microbial Pathogenesis. Nov, 2004 | Pubmed ID: 15519045 Denitrification Genes Regulate Brucella Virulence in Mice Journal of Bacteriology. Sep, 2004 | Pubmed ID: 15342571 Comparison of Bovine Leukemia Virus (BLV) and CMV Promoter-driven Reporter Gene Expression in BLV-infected and Non-infected Cells Genetic Vaccines and Therapy. Aug, 2004 | Pubmed ID: 15327692 Comparative Whole-genome Hybridization Reveals Genomic Islands in Brucella Species Journal of Bacteriology. Aug, 2004 | Pubmed ID: 15262941 Bovine Herpesvirus Tegument Protein VP22 Enhances Thymidine Kinase/ganciclovir Suicide Gene Therapy for Neuroblastomas Compared to Herpes Simplex Virus VP22 Journal of Virology. Apr, 2004 | Pubmed ID: 15047837 Role of Toll-like Receptor 4 in Induction of Cell-mediated Immunity and Resistance to Brucella Abortus Infection in Mice Infection and Immunity. Jan, 2004 | Pubmed ID: 14688095 The Proteasome As a Lipopolysaccharide-binding Protein in Macrophages: Differential Effects of Proteasome Inhibition on Lipopolysaccharide-induced Signaling Events Journal of Immunology (Baltimore, Md. : 1950). Aug, 2003 | Pubmed ID: 12874245 Microarray Analysis of MRNA Levels from RAW264.7 Macrophages Infected with Brucella Abortus Infection and Immunity. Mar, 2003 | Pubmed ID: 12595423 Molecular Host-pathogen Interaction in Brucellosis: Current Understanding and Future Approaches to Vaccine Development for Mice and Humans Clinical Microbiology Reviews. Jan, 2003 | Pubmed ID: 12525425 Rough Lipopolysaccharide from Brucella Abortus and Escherichia Coli Differentially Activates the Same Mitogen-activated Protein Kinase Signaling Pathways for Tumor Necrosis Factor Alpha in RAW 264.7 Macrophage-like Cells Infection and Immunity. Dec, 2002 | Pubmed ID: 12438403 Virulence Criteria for Brucella Abortus Strains As Determined by Interferon Regulatory Factor 1-deficient Mice Infection and Immunity. Dec, 2002 | Pubmed ID: 12438380 Molecular and Cellular Interactions Between Brucella Abortus Antigens and Host Immune Responses Veterinary Microbiology. Dec, 2002 | Pubmed ID: 12414160 Identification and Characterization of a Brucella Abortus ATP-binding Cassette Transporter Homolog to Rhizobium Meliloti ExsA and Its Role in Virulence and Protection in Mice Infection and Immunity. Sep, 2002 | Pubmed ID: 12183550 Molecular and Immunological Characterisation of Recombinant Brucella Abortus Glyceraldehyde-3-phosphate-dehydrogenase, a T- and B-cell Reactive Protein That Induces Partial Protection when Co-administered with an Interleukin-12-expressing Plasmid in a DNA Vaccine Formulation Journal of Medical Microbiology. Aug, 2002 | Pubmed ID: 12171297 Encephalomyocarditis and Mengo Viruses Productively Infect Murine T-lymphocyte Cell Lines but Not Fresh Ex Vivo Derived T Lymphocytes Viral Immunology. 2002 | Pubmed ID: 11952137 Susceptibility of IFN Regulatory Factor-1 and IFN Consensus Sequence Binding Protein-deficient Mice to Brucellosis Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002 | Pubmed ID: 11859135 Antigen Specific In Vivo Killing Assay using CFSE Labeled Target Cells Marina Durward1, Jerome Harms2, Gary Splitter2 1Pathology and Laboratory Medicine, University of Wisconsin-Madison, 2Pathobiological Sciences, University of Wisconsin-Madison JoVE 2250 Immunology and Infection
Antigen Specific In Vivo Killing Assay using CFSE Labeled Target Cells Marina Durward1, Jerome Harms2, Gary Splitter2 1Pathology and Laboratory Medicine, University of Wisconsin-Madison, 2Pathobiological Sciences, University of Wisconsin-Madison JoVE 2250 Immunology and Infection