George K. Gittes

Publications

• Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality
  Frontiers in Physiology. 2020  |   Pubmed ID: 33192543
• SMAD7 Enhances Adult β-cell Proliferation Without Significantly Affecting β-cell Function in Mice
  The Journal of Biological Chemistry. 04, 2020  |   Pubmed ID: 32122971
• Cellular Autophagy in Cells Plays a Role in the Maintenance of Islet Architecture
  Journal of the Endocrine Society. Nov, 2019  |   Pubmed ID: 31620668
• Evidence of a Developmental Origin for β-cell Heterogeneity Using a Dual Lineage-tracing Technology
  Development (Cambridge, England). 06, 2019  |   Pubmed ID: 31160417
• Islet α-cell Inflammation Induced By NF-κB Inducing Kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice
  Theranostics. 2018  |   Pubmed ID: 30613274
• Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes
  Cell Stem Cell. 01, 2018  |   Pubmed ID: 29304344
• Autophagy Protects Pancreatic Beta Cell Mass and Function in the Setting of a High-fat and High-glucose Diet
  Scientific Reports. 11, 2017  |   Pubmed ID: 29180700
• Gcg Knockin Mice As a Tool for Genetic Manipulation in Pancreatic Alpha Cells
  Diabetologia. 12, 2017  |   Pubmed ID: 28884202
• GLP-1/Exendin-4 Induces β-cell Proliferation Via the Epidermal Growth Factor Receptor
  Scientific Reports. 08, 2017  |   Pubmed ID: 28831150
• SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes
  Diabetes. 10, 2017  |   Pubmed ID: 28775125
• Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice
  The Journal of Biological Chemistry. 02, 2017  |   Pubmed ID: 28057752
• Epidermal Growth Factor Receptor Signaling Regulates β Cell Proliferation in Adult Mice
  The Journal of Biological Chemistry. Oct, 2016  |   Pubmed ID: 27587395
• A Synopsis of Factors Regulating Beta Cell Development and Beta Cell Mass
  Cellular and Molecular Life Sciences : CMLS. 10, 2016  |   Pubmed ID: 27105622
• Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects Against Experimental Murine Colitis
  The Journal of Biological Chemistry. May, 2016  |   Pubmed ID: 26969166
• The Role of ARF6 in Biliary Atresia
  PloS One. 2015  |   Pubmed ID: 26379158
• Defective Parasympathetic Innervation is Associated with Airway Branching Abnormalities in Experimental CDH
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2015  |   Pubmed ID: 25934671
• Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation
  Stem Cells Translational Medicine. Jun, 2015  |   Pubmed ID: 25900729
• Dynamic Imaging of Pancreatic Nuclear Factor κB (NF-κB) Activation in Live Mice Using Adeno-associated Virus (AAV) Infusion and Bioluminescence
  The Journal of Biological Chemistry. May, 2015  |   Pubmed ID: 25802340
• Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis
  The Journal of Biological Chemistry. Apr, 2014  |   Pubmed ID: 24519940
• α-Cells Are Dispensable in Postnatal Morphogenesis and Maturation of Mouse Pancreatic Islets
  American Journal of Physiology. Endocrinology and Metabolism. Oct, 2013  |   Pubmed ID: 23982158
• Neurogenin3 Activation is Not Sufficient to Direct Duct-to-beta Cell Transdifferentiation in the Adult Pancreas
  The Journal of Biological Chemistry. Aug, 2013  |   Pubmed ID: 23867457
• Hypoglycemia Reduces Vascular Endothelial Growth Factor A Production by Pancreatic Beta Cells As a Regulator of Beta Cell Mass
  The Journal of Biological Chemistry. Mar, 2013  |   Pubmed ID: 23378532
• TGFβ Receptor Signaling is Essential for Inflammation-induced but Not β-cell Workload-induced β-cell Proliferation
  Diabetes. Apr, 2013  |   Pubmed ID: 23248173
• Intestinal Epithelial Toll-like Receptor 4 Regulates Goblet Cell Development and is Required for Necrotizing Enterocolitis in Mice
  Gastroenterology. Sep, 2012  |   Pubmed ID: 22796522
• Defective Pulmonary Innervation and Autonomic Imbalance in Congenital Diaphragmatic Hernia
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2012  |   Pubmed ID: 22114150