Helen M. Arthur

Publications

• The Tissue-specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain
  PLoS Genetics. Apr, 2013  |   Pubmed ID: 23637638
• Deficiency for Endoglin in Tumor Vasculature Weakens the Endothelial Barrier to Metastatic Dissemination
  The Journal of Experimental Medicine. Mar, 2013  |   Pubmed ID: 23401487
• Endothelial Expression of TGFβ Type II Receptor is Required to Maintain Vascular Integrity During Postnatal Development of the Central Nervous System
  PloS One. 2012  |   Pubmed ID: 22745736
• Minimal Homozygous Endothelial Deletion of Eng with VEGF Stimulation is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse
  Cerebrovascular Diseases (Basel, Switzerland). 2012  |   Pubmed ID: 22571958
• Non-synonymous Variants in the SMAD6 Gene Predispose to Congenital Cardiovascular Malformation
  Human Mutation. Jan, 2012  |   Pubmed ID: 22275001
• Angiotensin II-induced Cardiomyocyte Hypertrophy in Vitro is TAK1-dependent and Smad2/3-independent
  Hypertension Research : Official Journal of the Japanese Society of Hypertension. Apr, 2012  |   Pubmed ID: 22072105
• Angiogenesis Regulation by TGFβ Signalling: Clues from an Inherited Vascular Disease
  Biochemical Society Transactions. Dec, 2011  |   Pubmed ID: 22103504
• TGFβ Signaling and Congenital Heart Disease: Insights from Mouse Studies
  Birth Defects Research. Part A, Clinical and Molecular Teratology. Jun, 2011  |   Pubmed ID: 21538815
• The H9C2 Cell Line and Primary Neonatal Cardiomyocyte Cells Show Similar Hypertrophic Responses in Vitro
  In Vitro Cellular & Developmental Biology. Animal. Feb, 2011  |   Pubmed ID: 21082279
• The TGFβ Type II Receptor Plays a Critical Role in the Endothelial Cells During Cardiac Development
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2010  |   Pubmed ID: 20652948
• Thalidomide Stimulates Vessel Maturation and Reduces Epistaxis in Individuals with Hereditary Hemorrhagic Telangiectasia
  Nature Medicine. Apr, 2010  |   Pubmed ID: 20364125
• Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin
  Circulation Research. Apr, 2010  |   Pubmed ID: 20224041
• Endoglin and Activin Receptor-like-kinase 1 Are Co-expressed in the Distal Vessels of the Lung: Implications for Two Familial Vascular Dysplasias, HHT and PAH
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Jan, 2009  |   Pubmed ID: 19015642
• Circulating Endothelial Progenitor Cells Exhibit Diurnal Variation
  Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2008  |   Pubmed ID: 18296584
• Extracellular Control of TGFbeta Signalling in Vascular Development and Disease
  Nature Reviews. Molecular Cell Biology. Nov, 2007  |   Pubmed ID: 17895899
• Generation of a Floxed Allele of the Mouse Endoglin Gene
  Genesis (New York, N.Y. : 2000). Jun, 2007  |   Pubmed ID: 17506087
• Endoglin Has a Crucial Role in Blood Cell-mediated Vascular Repair
  Circulation. Nov, 2006  |   Pubmed ID: 17088457
• Therapeutic Levels of Aspirin and Salicylate Directly Inhibit a Model of Angiogenesis Through a Cox-independent Mechanism
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2006  |   Pubmed ID: 17012253
• A Direct Interaction Between TGFbeta Activated Kinase 1 and the TGFbeta Type II Receptor: Implications for TGFbeta Signalling and Cardiac Hypertrophy
  Cardiovascular Research. Feb, 2006  |   Pubmed ID: 16360132
• Defective Paracrine Signalling by TGFbeta in Yolk Sac Vasculature of Endoglin Mutant Mice: a Paradigm for Hereditary Haemorrhagic Telangiectasia
  Development (Cambridge, England). Dec, 2004  |   Pubmed ID: 15548578
• Endoglin Promotes Endothelial Cell Proliferation and TGF-beta/ALK1 Signal Transduction
  The EMBO Journal. Oct, 2004  |   Pubmed ID: 15385967
• Vascular Endothelial Growth Factor Induces Abnormal Microvasculature in the Endoglin Heterozygous Mouse Brain
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2004  |   Pubmed ID: 14747750
• Mouse Model for Hereditary Hemorrhagic Telangiectasia Has a Generalized Vascular Abnormality
  Circulation. Apr, 2003  |   Pubmed ID: 12668501
• Endoglin Expression in Early Development is Associated with Vasculogenesis and Angiogenesis
  Mechanisms of Development. Jan, 2002  |   Pubmed ID: 11744382