Irina Smirnova Institute of Thermal Separation Processes Hamburg University of Technology Biography Publications Institution JoVE Articles Irina Smirnova has not added a biography. If you are Irina Smirnova and would like to personalize this page please email our Author Liaison for assistance. Publications Inhibition of Alpha-Glucosidase by Synthetic Derivatives of Lupane, Oleanane, Ursane and Dammarane Triterpenoids Natural Product Communications. Jan, 2016 | Pubmed ID: 26996014 Balance Between Short and Long Isoforms of CFLIP Regulates Fas-mediated Apoptosis in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26798068 Cutting Edge: Novel Tmem173 Allele Reveals Importance of STING N Terminus in Trafficking and Type I IFN Production Journal of Immunology (Baltimore, Md. : 1950). Jan, 2016 | Pubmed ID: 26685207 Transient Conformers of LacY Are Trapped by Nanobodies Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26512108 Synthesis and Antiviral Activity of Maleopimaric and Quinopimaric Acids' Derivatives Bioorganic & Medicinal Chemistry. Oct, 2015 | Pubmed ID: 26372075 Biocatalytic Carboxylation of Phenol Derivatives: Kinetics and Thermodynamics of the Biological Kolbe-Schmitt Synthesis The FEBS Journal. Apr, 2015 | Pubmed ID: 25652582 One-pot Synthesis of Hollongdione from Dipterocarpol Natural Product Communications. Oct, 2014 | Pubmed ID: 25522528 Outward-facing Conformers of LacY Stabilized by Nanobodies Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25512549 Synthesis and Anticancer Activity of Quinopimaric and Maleopimaric Acids’ Derivatives Bioorganic & Medicinal Chemistry. Nov, 2014 | Pubmed ID: 25440729 Neuroanatomical Distribution of Mechanoreceptors in the Human Cadaveric Shoulder Capsule and Labrum Journal of Anatomy. Sep, 2014 | Pubmed ID: 25040358 Real-time Conformational Changes in LacY Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24872451 Toll-like Receptor-mediated Down-regulation of the Deubiquitinase Cylindromatosis (CYLD) Protects Macrophages from Necroptosis in Wild-derived Mice The Journal of Biological Chemistry. May, 2014 | Pubmed ID: 24706750 Synthesis of an Organic Conductive Porous Material Using Starch Aerogels As Template for Chronic Invasive Electrodes Materials Science & Engineering. C, Materials for Biological Applications. Apr, 2014 | Pubmed ID: 24582238 Solubilization in Mixed Micelles Studied by Molecular Dynamics Simulations and COSMOmic The Journal of Physical Chemistry. B. Apr, 2014 | Pubmed ID: 24533791 Structure of Sugar-bound LacY Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24453216 Vertical Convective Coassembly of Refractory YSZ Inverse Opals from Crystalline Nanoparticles ACS Applied Materials & Interfaces. Dec, 2013 | Pubmed ID: 24319984 Mannose Receptor 1 Mediates Cellular Uptake and Endosomal Delivery of CpG-motif Containing Oligodeoxynucleotides Journal of Immunology (Baltimore, Md. : 1950). Dec, 2013 | Pubmed ID: 24184555 Single Mutations That Redirect Internal Proton Transfer in the Ba3 Oxidase from Thermus Thermophilus Biochemistry. Oct, 2013 | Pubmed ID: 24004023 Molecular Dynamics Simulation of SDS and CTAB Micellization and Prediction of Partition Equilibria with COSMOmic Langmuir : the ACS Journal of Surfaces and Colloids. Sep, 2013 | Pubmed ID: 23941607 Variations in Rodent Models of Type 1 Diabetes: Islet Morphology Journal of Diabetes Research. 2013 | Pubmed ID: 23762878 Comparison of Pretreatment Methods for Rye Straw in the Second Generation Biorefinery: Effect on Cellulose, Hemicellulose and Lignin Recovery Bioresource Technology. Aug, 2013 | Pubmed ID: 23748091 An Efficient Oxyfunctionalization of Quinopimaric Acid Derivatives with Ozone Natural Product Communications. Mar, 2013 | Pubmed ID: 23678794 Trp Replacements for Tightly Interacting Gly-Gly Pairs in LacY Stabilize an Outward-facing Conformation Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23671103 Combination of COSMOmic and Molecular Dynamics Simulations for the Calculation of Membrane-water Partition Coefficients Journal of Computational Chemistry. Jun, 2013 | Pubmed ID: 23447371 Prediction of Micelle/water and Liposome/water Partition Coefficients Based on Molecular Dynamics Simulations, COSMO-RS, and COSMOmic Langmuir : the ACS Journal of Surfaces and Colloids. Mar, 2013 | Pubmed ID: 23398189 Pressure Assisted Stabilization of Biocatalysts at Elevated Temperatures: Characterization by Dynamic Light Scattering Biotechnology and Bioengineering. Jun, 2013 | Pubmed ID: 23280599 COSMO-RS for the Prediction of the Retention Behavior in Micellar Liquid Chromatography Based on Partition Coefficients of Non-dissociated and Dissociated Solutes Journal of Chromatography. A. Jan, 2013 | Pubmed ID: 23273634 Partition Coefficients of Ionizable Solutes in Mixed Nonionic/ionic Micellar Systems Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2013 | Pubmed ID: 23237203 Construction of a Two-parameter Empirical Model of Left Ventricle Wall Motion Using Cardiac Tagged Magnetic Resonance Imaging Data Biomedical Engineering Online. 2012 | Pubmed ID: 23095713 Role of Protons in Sugar Binding to LacY Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23033496 Hydrothermal Pentose to Furfural Conversion and Simultaneous Extraction with SC-CO2--kinetics and Application to Biomass Hydrolysates Bioresource Technology. Nov, 2012 | Pubmed ID: 22947445 Exercise-induced Cardiac Performance in Autoimmune (type 1) Diabetes is Associated with a Decrease in Myocardial Diacylglycerol Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2012 | Pubmed ID: 22797313 Effects of Acute and Chronic Hyperglycemia on the Neurochemical Profiles in the Rat Brain with Streptozotocin-induced Diabetes Detected Using in Vivo ¹H MR Spectroscopy at 9.4 T Journal of Neurochemistry. May, 2012 | Pubmed ID: 22353009 Time-dependent Alterations in Rat Macrovessels with Type 1 Diabetes Experimental Diabetes Research. 2012 | Pubmed ID: 22315586 Kinetic Investigation of a Solvent-free, Chemoenzymatic Reaction Sequence Towards Enantioselective Synthesis of a β-amino Acid Ester Biotechnology and Bioengineering. Jun, 2012 | Pubmed ID: 22275046 Experimental Methods and Prediction with COSMO-RS to Determine Partition Coefficients in Complex Surfactant Systems Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2012 | Pubmed ID: 22091584 Liporetro-D-peptides - a Novel Class of Highly Selective Thrombin Inhibitors Thrombosis Research. Apr, 2012 | Pubmed ID: 22079445 Sugar Recognition by CscB and LacY Biochemistry. Dec, 2011 | Pubmed ID: 22106930 Lactose Permease and the Alternating Access Mechanism Biochemistry. Nov, 2011 | Pubmed ID: 21995338 Opening the Periplasmic Cavity in Lactose Permease is the Limiting Step for Sugar Binding Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21896727 Crystal Structures of DntR Inducer Binding Domains in Complex with Salicylate Offer Insights into the Activation of LysR-type Transcriptional Regulators Molecular Microbiology. Jul, 2011 | Pubmed ID: 21692874 Inhibition of the EGF Receptor and ERK1/2 Signaling Pathways Rescues the Human Epidermoid Carcinoma A431 Cells from IFNγ-induced Apoptosis Cell Cycle (Georgetown, Tex.). Jul, 2011 | Pubmed ID: 21606674 Comparison of Different Pretreatment Methods for Lignocellulosic Materials. Part I: Conversion of Rye Straw to Valuable Products Bioresource Technology. Apr, 2011 | Pubmed ID: 21349703 Low Insulin Content of Large Islet Population is Present in Situ and in Isolated Islets Islets. Jan-Feb, 2011 | Pubmed ID: 21325888 Comparison of Different Pretreatment Methods for Lignocellulosic Materials. Part II: Influence of Pretreatment on the Properties of Rye Straw Lignin Bioresource Technology. Mar, 2011 | Pubmed ID: 21208799 The Alternating Access Transport Mechanism in LacY The Journal of Membrane Biology. Jan, 2011 | Pubmed ID: 21161516 Exercise Training Prevents Endometrial Hyperplasia and Biomarkers for Endometrial Cancer in Rat Model of Type 1 Diabetes Journal of Clinical Medicine Research. Oct, 2010 | Pubmed ID: 21629542 Reduction of Diffusion Barriers in Isolated Rat Islets Improves Survival, but Not Insulin Secretion or Transplantation Outcome Organogenesis. Apr-Jun, 2010 | Pubmed ID: 20885858 Electrocardiographic Changes with the Onset of Diabetes and the Impact of Aerobic Exercise Training in the Zucker Diabetic Fatty (ZDF) Rat Cardiovascular Diabetology. 2010 | Pubmed ID: 20860788 Functional Role of Thr-312 and Thr-315 in the Proton-transfer Pathway in Ba3 Cytochrome C Oxidase from Thermus Thermophilus Biochemistry. Aug, 2010 | Pubmed ID: 20677778 Delineating Electrogenic Reactions During Lactose/H+ Symport Biochemistry. Jul, 2010 | Pubmed ID: 20568736 IRAK1BP1 Inhibits Inflammation by Promoting Nuclear Translocation of NF-kappaB P50 Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534545 Intracellular Ca2+ Regulating Proteins in Vascular Smooth Muscle Cells Are Altered with Type 1 Diabetes Due to the Direct Effects of Hyperglycemia Cardiovascular Diabetology. 2010 | Pubmed ID: 20122173 Prosurvival and Proapoptotic Functions of ERK1/2 Activation in Murine Thymocytes in Vitro Cellular Immunology. 2010 | Pubmed ID: 19914607 Resistance Exercise Training Lowers HbA1c More Than Aerobic Training in Adults with Type 2 Diabetes Diabetology & Metabolic Syndrome. 2009 | Pubmed ID: 20003276 Probing of the Rates of Alternating Access in LacY with Trp Fluorescence Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19959662 Residues in the H+ Translocation Site Define the PKa for Sugar Binding to LacY Biochemistry. Sep, 2009 | Pubmed ID: 19689129 A Mutation in Irak2c Identifies IRAK-2 As a Central Component of the TLR Regulatory Network of Wild-derived Mice The Journal of Experimental Medicine. Jul, 2009 | Pubmed ID: 19564352 Electrophysiological Characterization of LacY Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19383792 A Hemidominant Naip5 Allele in Mouse Strain MOLF/Ei-derived Macrophages Restricts Legionella Pneumophila Intracellular Growth Infection and Immunity. Jan, 2009 | Pubmed ID: 18981241 Electron and Proton Transfer in the Ba(3) Oxidase from Thermus Thermophilus Journal of Bioenergetics and Biomembranes. Aug, 2008 | Pubmed ID: 18752061 Protonation and Sugar Binding to LacY Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18567672 A Model-based Time-reversal of Left Ventricular Motion Improves Cardiac Motion Analysis Using Tagged MRI Data Biomedical Engineering Online. 2008 | Pubmed ID: 18489766 Forward Genetic Analysis of Toll-like Receptor Responses in Wild-derived Mice Reveals a Novel Antiinflammatory Role for IRAK1BP1 The Journal of Experimental Medicine. Feb, 2008 | Pubmed ID: 18268037 Sugar Binding Induces an Outward Facing Conformation of LacY Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17925435 In Vivo and in Vitro Investigation of Transcriptional Regulation by DntR Journal of Molecular Biology. Sep, 2007 | Pubmed ID: 17681542 Longitudinal Magnetic Resonance Imaging of Spinal Cord Injury in Mouse: Changes in Signal Patterns Associated with the Inflammatory Response Magnetic Resonance Imaging. Jun, 2007 | Pubmed ID: 17540277 Single-molecule FRET Reveals Sugar-induced Conformational Dynamics in LacY Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17502603 Genetic Analysis of the Innate Immune Responses in Wild-derived Inbred Strains of Mice European Journal of Immunology. Jan, 2007 | Pubmed ID: 17163447 Exercise Training Improves Cardiac Performance in Diabetes: in Vivo Demonstration with Quantitative Cine-MRI Analyses Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2007 | Pubmed ID: 17082374 Direct Sugar Binding to LacY Measured by Resonance Energy Transfer Biochemistry. Dec, 2006 | Pubmed ID: 17176050 Mice Expressing High Levels of Soluble CD14 Retain LPS in the Circulation and Are Resistant to LPS-induced Lethality European Journal of Immunology. Nov, 2006 | Pubmed ID: 17039565 Energetics of Ligand-induced Conformational Flexibility in the Lactose Permease of Escherichia Coli The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 17003033 Hepatitis C Virus Core Protein Transforms Murine Fibroblasts by Promoting Genomic Instability Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2006 | Pubmed ID: 16988473 Different Transformation Pathways of Murine Fibroblast NIH 3T3 Cells by Hepatitis C Virus Core and NS3 Proteins Cell Biology International. Nov, 2006 | Pubmed ID: 16949842 Cardiac Dysfunction in the Diabetic Rat: Quantitative Evaluation Using High Resolution Magnetic Resonance Imaging Cardiovascular Diabetology. 2006 | Pubmed ID: 16595006 Sequence Alignment and Homology Threading Reveals Prokaryotic and Eukaryotic Proteins Similar to Lactose Permease Journal of Molecular Biology. May, 2006 | Pubmed ID: 16574153 Conservation of Residues Involved in Sugar/H(+) Symport by the Sucrose Permease of Escherichia Coli Relative to Lactose Permease Journal of Molecular Biology. May, 2006 | Pubmed ID: 16574149 Manipulating Phospholipids for Crystallization of a Membrane Transport Protein Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16446422 Characterization of Alterations in Diabetic Myocardial Tissue Using High Resolution MRI The International Journal of Cardiovascular Imaging. Feb, 2006 | Pubmed ID: 16362172 Ex Vivo Magnetic Resonance Imaging of Rat Spinal Cord at 9.4 T Magnetic Resonance Imaging. May, 2005 | Pubmed ID: 15919607 Interhelical Packing Modulates Conformational Flexibility in the Lactose Permease of Escherichia Coli Biochemistry. May, 2005 | Pubmed ID: 15909981 Dissolution Rate Enhancement by Adsorption of Poorly Soluble Drugs on Hydrophilic Silica Aerogels Pharmaceutical Development and Technology. Nov, 2004 | Pubmed ID: 15581080 Spontaneous Ca2+ Oscillations in Subcellular Compartments of Vascular Smooth Muscle Cells Rely on Different Ca2+ Pools Cell Research. Oct, 2004 | Pubmed ID: 15538970 Exercise Attenuates Diabetes-induced Ultrastructural Changes in Rat Cardiac Tissue Medicine and Science in Sports and Exercise. Nov, 2004 | Pubmed ID: 15514499 Development of a Bacterial Biosensor for Nitrotoluenes: the Crystal Structure of the Transcriptional Regulator DntR Journal of Molecular Biology. Jul, 2004 | Pubmed ID: 15210343 Immunization with Hepatitis C Virus Core Gene Triggers Potent T-cell Response, but Affects CD4+ T-cells Vaccine. Apr, 2004 | Pubmed ID: 15068848 Role of YidC in Folding of Polytopic Membrane Proteins The Journal of Cell Biology. Apr, 2004 | Pubmed ID: 15067017 The Lactose Permease of Escherichia Coli: Overall Structure, the Sugar-binding Site and the Alternating Access Model for Transport FEBS Letters. Nov, 2003 | Pubmed ID: 14630326 Structure and Mechanism of the Lactose Permease of Escherichia Coli Science (New York, N.Y.). Aug, 2003 | Pubmed ID: 12893935 Signal Transduction Pathways in Mast Cell Granule-mediated Endothelial Cell Activation Mediators of Inflammation. Apr, 2003 | Pubmed ID: 12775357 Assay of Locus-specific Genetic Load Implicates Rare Toll-like Receptor 4 Mutations in Meningococcal Susceptibility Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12730365 A Mutation in the Lactose Permease of Escherichia Coli That Decreases Conformational Flexibility and Increases Protein Stability Biochemistry. Mar, 2003 | Pubmed ID: 12627968 Mammalian Metal Response Element-binding Transcription Factor-1 Functions As a Zinc Sensor in Yeast, but Not As a Sensor of Cadmium or Oxidative Stress Nucleic Acids Research. Jul, 2002 | Pubmed ID: 12136095 Preparation of Biopolymer Aerogels Using Green Solvents Raman Subrahmanyam1, Pavel Gurikov1, Imke Meissner1, Irina Smirnova1 1Institute of Thermal Separation Processes, Hamburg University of Technology JoVE 54116 Chemistry
Preparation of Biopolymer Aerogels Using Green Solvents Raman Subrahmanyam1, Pavel Gurikov1, Imke Meissner1, Irina Smirnova1 1Institute of Thermal Separation Processes, Hamburg University of Technology JoVE 54116 Chemistry
