Translate this page to:
In JoVE (1)
Other Publications (6)
Articles by James Wysock in JoVE
Single Port Donor Nephrectomy
David B Leeser*1, James Wysock*2, S Elena Gimenez2, Sandip Kapur1, Joseph Del Pizzo*2
1Surgery, Weill Cornell Medical College of Cornell University, 2Urology, Weill Cornell Medical College of Cornell University
Single port laparoscopic surgery is changing the standard of care in surgical care like nothing since the laparoscopic technique was introduced 20 years ago. We present out technique of single port donor nephrectomy using the Gelpoint device. We have successfully performed this surgery in 100 patients.
Other articles by James Wysock on PubMed
Erectile Function, Sexual Drive, and Ejaculatory Function After Reconstructive Surgery for Anterior Urethral Stricture Disease
BJU International. Mar, 2007 | Pubmed ID: 17155967
To evaluate the effect of urethral reconstructive surgery on sexual drive, erectile function and ejaculation.
Urology. Mar, 2007 | Pubmed ID: 17382176
Angiosarcoma of the bladder is extremely rare and carries a dismal prognosis because of the uniformly high-grade and aggressive tumor biology of the neoplasm. We report the long-term disease-free survival of 1 patient, treated with multimodal therapy, whom we have previously reported on. Six years after the initial presentation, the patient died, and the postmortem analysis revealed no evidence of residual disease. Our case represents the longest reported survival of a patient with angiosarcoma of the bladder.
Proceedings - Society of Photo-Optical Instrumentation Engineers. 2009 | Pubmed ID: 19360140
At the time of diagnosis, approximately 75% of bladder cancers are non-muscle invasive. Appropriate diagnosis and surgical resection at this stage improves prognosis dramatically. However, these lesions, being small and/or flat, are often missed by conventional white-light cystoscopes. Furthermore, it is difficult to assess the surgical margin for negativity using conventional cystoscopes. Resultantly, the recurrence rates in patients with early bladder cancer are very high. This is currently addressed by repeat cystoscopies and biopsies, which can last throughout the life of a patient, increasing cost and patient morbidity. Multiphoton endoscopes offer a potential solution, allowing real time, non-invasive biopsies of the human bladder, as well as an up-close assessment of the resection margin. While miniaturization of the Multiphoton microscope into an endoscopic format is currently in progress, we present results here indicating that Multiphoton imaging (using a bench-top Multiphoton microscope) can indeed identify cancers in fresh, unfixed human bladder biopsies. Multiphoton images are acquired in two channels: (1) broadband autofluorescence from cells, and (2) second harmonic generation (SHG), mostly by tissue collagen. These images are then compared with gold standard hematoxylin/eosin (H&E) stained histopathology slides from the same specimen. Based on a "training set" and a very small "blinded set" of samples, we have found excellent correlation between the Multiphoton and histopathological diagnoses. A larger blinded analysis by two independent uropathologists is currently in progress. We expect that the conclusion of this phase will provide us with diagnostic accuracy estimates, as well as the degree of inter-observer heterogeneity.
Anatomical Retro-apical Technique of Synchronous (posterior and Anterior) Urethral Transection: a Novel Approach for Ameliorating Apical Margin Positivity During Robotic Radical Prostatectomy
BJU International. Nov, 2010 | Pubmed ID: 20377582
To describe a novel synchronous approach to apical dissection during robotic-assisted radical prostatectomy (RARP) which augments circumferential visual appreciation of the prostatic apex and membranous urethra anatomy, and assess its effect on apical margin positivity.
The Journal of Urology. Nov, 2010 | Pubmed ID: 20850822
We present our initial experience in 40 patients undergoing laparoendoscopic single site donor nephrectomy.
Outcomes and Complications After 532 Nm Laser Prostatectomy in Anticoagulated Patients with Benign Prostatic Hyperplasia
The Journal of Urology. Sep, 2011 | Pubmed ID: 21791350
Patients on anticoagulation are at high risk for bleeding after electrocautery transurethral resection of the prostate or open prostatectomy and they are often denied surgery for symptomatic benign prostatic hyperplasia. Using photoselective vaporization of the prostate, patients at high risk may safely undergo surgery. We explored outcomes and complications after photoselective vaporization of the prostate in an anticoagulated, high risk cohort.