Jan Rupp Institute of Medical Microbiology and Hygiene University of Lübeck Biography Publications Institution JoVE Articles Jan Rupp has not added a biography. If you are Jan Rupp and would like to personalize this page please email our Author Liaison for assistance. Publications Association Between Azithromycin Therapy and Duration of Bacterial Shedding Among Patients with Shiga Toxin-producing Enteroaggregative Escherichia Coli O104:H4 JAMA : the Journal of the American Medical Association. Mar, 2012 | Pubmed ID: 22416100 When Oxygen Runs Short: the Microenvironment Drives Host-pathogen Interactions Microbes and Infection / Institut Pasteur. Apr, 2012 | Pubmed ID: 22133978 Targeting of a Chlamydial Protease Impedes Intracellular Bacterial Growth PLoS Pathogens. Sep, 2011 | Pubmed ID: 21990969 Fluorescence Lifetime Imaging Unravels C. Trachomatis Metabolism and Its Crosstalk with the Host Cell PLoS Pathogens. Jul, 2011 | Pubmed ID: 21779161 Impact of a Low-oxygen Environment on the Efficacy of Antimicrobials Against Intracellular Chlamydia Trachomatis Antimicrobial Agents and Chemotherapy. May, 2011 | Pubmed ID: 21321137 The T-helper Cell Type 1 Immune Response to Gram-negative Bacterial Infections is Impaired in COPD American Journal of Respiratory and Critical Care Medicine. Jan, 2011 | Pubmed ID: 20709824 Hypoxia Abrogates Antichlamydial Properties of IFN-γ in Human Fallopian Tube Cells in Vitro and Ex Vivo Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20974954 Divergent Modulation of Chlamydia Pneumoniae Infection Cycle in Human Monocytic and Endothelial Cells by Iron, Tryptophan Availability and Interferon Gamma Immunobiology. Sep-Oct, 2010 | Pubmed ID: 20646782 The TGF-beta-pseudoreceptor BAMBI is Strongly Expressed in COPD Lungs and Regulated by Nontypeable Haemophilus Influenzae Respiratory Research. 2010 | Pubmed ID: 20513241 Chlamydia Pneumoniae Infection and Alzheimer's Disease: a Connection to Remember? Medical Microbiology and Immunology. Nov, 2010 | Pubmed ID: 20445987 Chlamydia Pneumoniae-induced Memory CD4+ T-cell Activation in Human Peripheral Blood Correlates with Distinct Antibody Response Patterns Clinical and Vaccine Immunology : CVI. May, 2010 | Pubmed ID: 20219874 The CD40-CD40L Pathway Contributes to the Proinflammatory Function of Intestinal Epithelial Cells in Inflammatory Bowel Disease The American Journal of Pathology. Apr, 2010 | Pubmed ID: 20133813 Proliferative Stimulation of the Vascular Endothelin-1 Axis in Vitro and Ex Vivo by Infection with Chlamydia Pneumoniae Thrombosis and Haemostasis. Oct, 2009 | Pubmed ID: 19806261 Chlamydia Pneumoniae Hides Inside Apoptotic Neutrophils to Silently Infect and Propagate in Macrophages PloS One. 2009 | Pubmed ID: 19547701 Immunomodulatory Effects of Sanglifehrin A in the Innate and Acquired Immune Response of Neonatal Whole Blood Cells Immunobiology. 2009 | Pubmed ID: 19215806 159C>T CD14 Genotype--functional Effects on Innate Immune Responses in Term Neonates Human Immunology. Jun, 2008 | Pubmed ID: 18571004 Modulation of the Inflammatory Response to Streptococcus Pneumoniae in a Model of Acute Lung Tissue Infection American Journal of Respiratory Cell and Molecular Biology. Nov, 2008 | Pubmed ID: 18483419 Immunoproteomic Identification and Serological Responses to Novel Chlamydia Pneumoniae Antigens That Are Associated with Persistent C. Pneumoniae Infections Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18390732 Experimental Induction and Three-dimensional Two-photon Imaging of Conjunctiva-associated Lymphoid Tissue Investigative Ophthalmology & Visual Science. Apr, 2008 | Pubmed ID: 18385070 Variation in the Mutation Frequency Determining Quinolone Resistance in Chlamydia Trachomatis Serovars L2 and D The Journal of Antimicrobial Chemotherapy. Jan, 2008 | Pubmed ID: 18033786 Genetic Diversity of the Obligate Intracellular Bacterium Chlamydophila Pneumoniae by Genome-wide Analysis of Single Nucleotide Polymorphisms: Evidence for Highly Clonal Population Structure BMC Genomics. 2007 | Pubmed ID: 17916241 Prevalence, Genetic Conservation and Transmissibility of the Chlamydia Pneumoniae Bacteriophage (phiCpn1) FEMS Microbiology Letters. Aug, 2007 | Pubmed ID: 17559388 Chlamydia Pneumoniae Directly Interferes with HIF-1alpha Stabilization in Human Host Cells Cellular Microbiology. Sep, 2007 | Pubmed ID: 17490410 Disparate Innate Immune Responses to Persistent and Acute Chlamydia Pneumoniae Infection in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. Apr, 2007 | Pubmed ID: 17290045 Perfluorocarbons Decrease Chlamydophila Pneumoniae-mediated Inflammatory Responses of Rat Type II Pneumocytes in Vitro Pediatric Research. Sep, 2006 | Pubmed ID: 16857767 Be Aware of the Possibility of False-positive Results in Single-locus PCR Assays for Methicillin-resistant Staphylococcus Aureus Journal of Clinical Microbiology. Jun, 2006 | Pubmed ID: 16757652 Single-nucleotide-polymorphism-specific PCR for Quantification and Discrimination of Chlamydia Pneumoniae Genotypes by Use of a "locked" Nucleic Acid Applied and Environmental Microbiology. May, 2006 | Pubmed ID: 16672536 Tissue Microarrays from HOPE-fixed Specimens Allow for Enhanced High Throughput Molecular Analyses in Paraffin-embedded Material Pathology, Research and Practice. 2005 | Pubmed ID: 16259114 Critical Investigation of the CD14 Promoter Polymorphism: Lack of a Role for in Vitro Cytokine Response and Membrane CD14 Expression Clinical and Diagnostic Laboratory Immunology. Oct, 2005 | Pubmed ID: 16210494 Chlamydophila Pneumoniae. Mechanisms of Target Cell Infection and Activation Thrombosis and Haemostasis. Aug, 2005 | Pubmed ID: 16113821 The Interleukin-6 -174 Promoter Polymorphism is Associated with Extrapulmonary Bacterial Dissemination in Streptococcus Pneumoniae Infection Cytokine. Aug, 2005 | Pubmed ID: 16005243 Growth Cycle-dependent Pharmacodynamics of Antichlamydial Drugs Antimicrobial Agents and Chemotherapy. May, 2005 | Pubmed ID: 15855506 Chlamydia Pneumoniae Infection Promotes a Proliferative Phenotype in the Vasculature Through Egr-1 Activation in Vitro and in Vivo Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15722416 Transmission of Chlamydia Pneumoniae Infection from Blood Monocytes to Vascular Cells in a Novel Transendothelial Migration Model FEMS Microbiology Letters. Jan, 2005 | Pubmed ID: 15621438 Serine-to-asparagine Substitution in the GyrA Gene Leads to Quinolone Resistance in Moxifloxacin-exposed Chlamydia Pneumoniae Antimicrobial Agents and Chemotherapy. Jan, 2005 | Pubmed ID: 15616321 Asymptomatic Carotid Atherosclerosis is Associated with Circulating Chlamydia Pneumoniae DNA in Younger Normotensive Subjects in a General Population Survey Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2005 | Pubmed ID: 15550694 Cox-2 Inhibition Abrogates Chlamydia Pneumoniae-induced PGE2 and MMP-1 Expression Biochemical and Biophysical Research Communications. Jul, 2004 | Pubmed ID: 15240110 Alveolar Epithelial Cells Type II Are Major Target Cells for C. Pneumoniae in Chronic but Not in Acute Respiratory Infection FEMS Immunology and Medical Microbiology. Jul, 2004 | Pubmed ID: 15196568 Endothelial Chlamydia Pneumoniae Infection Promotes Oxidation of LDL Biochemical and Biophysical Research Communications. Jun, 2004 | Pubmed ID: 15178434 First-choice Antibiotics at Subinhibitory Concentrations Induce Persistence of Chlamydia Pneumoniae Antimicrobial Agents and Chemotherapy. Apr, 2004 | Pubmed ID: 15047553 A Human Fallopian Tube Model for Investigation of C. trachomatis Infections Stefan Jerchel1, Gudrun Knebel2, Peter König2, Michael K. Bohlmann3, Jan Rupp1,4 1Institute of Medical Microbiology and Hygiene, University of Lübeck, 2Institute of Anatomie, University of Lübeck, 3Department of Obstetrics and Gynecology, University Hospital of Schleswig-Holstein, University of Lübeck, 4Medical Clinic III, University Hospital of Schleswig-Holstein, University of Lübeck JoVE 4036 Medicine
A Human Fallopian Tube Model for Investigation of C. trachomatis Infections Stefan Jerchel1, Gudrun Knebel2, Peter König2, Michael K. Bohlmann3, Jan Rupp1,4 1Institute of Medical Microbiology and Hygiene, University of Lübeck, 2Institute of Anatomie, University of Lübeck, 3Department of Obstetrics and Gynecology, University Hospital of Schleswig-Holstein, University of Lübeck, 4Medical Clinic III, University Hospital of Schleswig-Holstein, University of Lübeck JoVE 4036 Medicine
