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In JoVE (1)
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Articles by Janette N. Zara in JoVE
Use of Human Perivascular Stem Cells for Bone Regeneration
Aaron W. James*1, Janette N. Zara*2, Mirko Corselli2, Michael Chiang1, Wei Yuan2, Virginia Nguyen1, Asal Askarinam1, Raghav Goyal1, Ronald K. Siu3, Victoria Scott1, Min Lee3, Kang Ting1, Bruno Péault2,4, Chia Soo2
1Dental and Craniofacial Research Institute and Section of Orthodontics, School of Dentistry, UCLA, 2UCLA and Orthopaedic Hospital, Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, UCLA, 3Department of Bioengineering, UCLA, 4Center for Cardiovascular Science, University of Edinburgh
Human perivascular stem cells (PSCs) are a novel stem cell class for skeletal tissue regeneration similar to mesenchymal stem cells (MSCs). PSCs can be isolated by FACS (fluorescence activated cell sorting) from adipose tissue procured during standard liposuction procedures, then combined with an osteoinductive scaffold to achieve bone formation in vivo.