Javier Traba Cardiovascular Branch, National Heart, Lung and Blood Institute National Institutes of Health Biography Publications Institution JoVE Articles Javier Traba has not added a biography. If you are Javier Traba and would like to personalize this page please email our Author Liaison for assistance. Publications -endocytosis of Intact IL-15Rα-IL-15 Complex from Presenting Cells into NK Cells Favors Signaling for Proliferation Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31871169 Loss of GCN5L1 in Cardiac Cells Disrupts Glucose Metabolism and Promotes Cell Death Via Reduced Akt/mTORC2 Signaling The Biochemical Journal. 06, 2019 | Pubmed ID: 31138772 Cardiac-specific Deletion of GCN5L1 Restricts Recovery from Ischemia-reperfusion Injury Journal of Molecular and Cellular Cardiology. 04, 2019 | Pubmed ID: 30776374 Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4 T Cell Activation Journal of Immunology (Baltimore, Md. : 1950). 12, 2018 | Pubmed ID: 30373851 A Pilot Study To Investigate the Immune-Modulatory Effects of Fasting in Steroid-Naive Mild Asthmatics Journal of Immunology (Baltimore, Md. : 1950). 09, 2018 | Pubmed ID: 30021766 Second Signals Rescue B Cells from Activation-induced Mitochondrial Dysfunction and Death Nature Immunology. 08, 2018 | Pubmed ID: 29988090 ATP-degrading ENPP1 is Required for Survival (or Persistence) of Long-lived Plasma Cells Scientific Reports. 12, 2017 | Pubmed ID: 29259245 Prolonged Fasting Suppresses Mitochondrial NLRP3 Inflammasome Assembly and Activation Via SIRT3-mediated Activation of Superoxide Dismutase 2 The Journal of Biological Chemistry. 07, 2017 | Pubmed ID: 28584055 Glutamate Excitotoxicity and Ca2+-regulation of Respiration: Role of the Ca2+ Activated Mitochondrial Transporters (CaMCs) Biochimica Et Biophysica Acta. Aug, 2016 | Pubmed ID: 27060251 Fasting and Refeeding Differentially Regulate NLRP3 Inflammasome Activation in Human Subjects The Journal of Clinical Investigation. Nov, 2015 | Pubmed ID: 26529255 Mitochondrial ATP-Mg/Pi Carrier SCaMC-3/Slc25a23 Counteracts PARP-1-dependent Fall in Mitochondrial ATP Caused by Excitotoxic Insults in Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2015 | Pubmed ID: 25716855 Regulation of Autophagy and Mitophagy by Nutrient Availability and Acetylation Biochimica Et Biophysica Acta. Apr, 2014 | Pubmed ID: 24525425 Silencing of the Charcot-Marie-Tooth Disease-associated Gene GDAP1 Induces Abnormal Mitochondrial Distribution and Affects Ca2+ Homeostasis by Reducing Store-operated Ca2+ Entry Neurobiology of Disease. Jul, 2013 | Pubmed ID: 23542510 Glucagon Regulation of Oxidative Phosphorylation Requires an Increase in Matrix Adenine Nucleotide Content Through Ca2+ Activation of the Mitochondrial ATP-Mg/Pi Carrier SCaMC-3 The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23344948 SCaMC-1Like a Member of the Mitochondrial Carrier (MC) Family Preferentially Expressed in Testis and Localized in Mitochondria and Chromatoid Body PloS One. 2012 | Pubmed ID: 22792342 Adenine Nucleotide Transporters in Organelles: Novel Genes and Functions Cellular and Molecular Life Sciences : CMLS. Apr, 2011 | Pubmed ID: 21207102 Transport of Adenine Nucleotides in the Mitochondria of Saccharomyces Cerevisiae: Interactions Between the ADP/ATP Carriers and the ATP-Mg/Pi Carrier Mitochondrion. Apr, 2009 | Pubmed ID: 19460304 Characterization of SCaMC-3-like/slc25a41, a Novel Calcium-independent Mitochondrial ATP-Mg/Pi Carrier The Biochemical Journal. Feb, 2009 | Pubmed ID: 18928449 Yeast Mitochondria Import ATP Through the Calcium-dependent ATP-Mg/Pi Carrier Sal1p, and Are ATP Consumers During Aerobic Growth in Glucose Molecular Microbiology. Aug, 2008 | Pubmed ID: 18485069 The Calcium-dependent ATP-Mg/Pi Mitochondrial Carrier is a Target of Glucose-induced Calcium Signalling in Saccharomyces Cerevisiae The Biochemical Journal. Dec, 2005 | Pubmed ID: 16111475 Analysis of Human Natural Killer Cell Metabolism Javier Traba1,2, Thomas A. Waldmann3, Olga M. Anton3 1Cardiovascular Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 2Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 3Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health JoVE 61466 Immunology and Infection An Optimized Protocol to Analyze Glycolysis and Mitochondrial Respiration in Lymphocytes Javier Traba*1, Pietro Miozzo*2, Billur Akkaya3, Susan K. Pierce2, Munir Akkaya2 1Laboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, 2Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 3Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health JoVE 54918 Immunology and Infection
Analysis of Human Natural Killer Cell Metabolism Javier Traba1,2, Thomas A. Waldmann3, Olga M. Anton3 1Cardiovascular Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 2Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 3Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health JoVE 61466 Immunology and Infection
An Optimized Protocol to Analyze Glycolysis and Mitochondrial Respiration in Lymphocytes Javier Traba*1, Pietro Miozzo*2, Billur Akkaya3, Susan K. Pierce2, Munir Akkaya2 1Laboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, 2Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 3Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health JoVE 54918 Immunology and Infection