Jean C. Lee Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital Harvard Medical School Biography Publications Institution JoVE Articles Jean C. Lee has not added a biography. If you are Jean C. Lee and would like to personalize this page please email our Author Liaison for assistance. Publications Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine Against Staphylococcus Aureus in a Rat Model of Osteomyelitis Infection and Immunity. Jan, 2014 | Pubmed ID: 24126523 Prevention of Staphylococcus Aureus Infections by Glycoprotein Vaccines Synthesized in Escherichia Coli The Journal of Infectious Diseases. Dec, 2013 | Pubmed ID: 24308931 Acapsular Clinical Staphylococcus Aureus Isolates Lack Agr Function Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. Oct, 2013 | Pubmed ID: 24224619 Extended Staphylococcus Aureus Persistence in Cystic Fibrosis is Associated with Bacterial Adaptation International Journal of Medical Microbiology : IJMM. Dec, 2013 | Pubmed ID: 24183484 Novel Synthetic (poly)glycerolphosphate-based Antistaphylococcal Conjugate Vaccine Infection and Immunity. Jul, 2013 | Pubmed ID: 23649092 Production of Capsular Polysaccharide Does Not Influence Staphylococcus Aureus Vancomycin Susceptibility BMC Microbiology. 2013 | Pubmed ID: 23522028 Opsonic and Protective Properties of Antibodies Raised to Conjugate Vaccines Targeting Six Staphylococcus Aureus Antigens PloS One. 2012 | Pubmed ID: 23077517 Staphylococcus Aureus NorD, a Putative Efflux Pump Coregulated with the Opp1 Oligopeptide Permease, Contributes Selectively to Fitness in Vivo Journal of Bacteriology. Dec, 2012 | Pubmed ID: 23042988 A Microfluidic Platform for Rapid, Stress-induced Antibiotic Susceptibility Testing of Staphylococcus Aureus Lab on a Chip. Nov, 2012 | Pubmed ID: 22968495 Reduced Neutrophil Apoptosis in Diabetic Mice During Staphylococcal Infection Leads to Prolonged Tnfα Production and Reduced Neutrophil Clearance PloS One. 2011 | Pubmed ID: 21912601 The Zwitterionic Cell Wall Teichoic Acid of Staphylococcus Aureus Provokes Skin Abscesses in Mice by a Novel CD4+ T-cell-dependent Mechanism PloS One. 2010 | Pubmed ID: 20949105 Animal and Human Antibodies to Distinct Staphylococcus Aureus Antigens Mutually Neutralize Opsonic Killing and Protection in Mice The Journal of Clinical Investigation. Sep, 2010 | Pubmed ID: 20739753 Characterization of the Structure and Biological Functions of a Capsular Polysaccharide Produced by Staphylococcus Saprophyticus Journal of Bacteriology. Sep, 2010 | Pubmed ID: 20639341 The Effectiveness of the Controlled Release of Gentamicin from Polyelectrolyte Multilayers in the Treatment of Staphylococcus Aureus Infection in a Rabbit Bone Model Biomaterials. Aug, 2010 | Pubmed ID: 20488534 Proteolytic Fragments of Chromogranins A and B Represent Major Soluble Components of Chromaffin Granules, Illustrated by Two-dimensional Proteomics with NH(2)-terminal Edman Peptide Sequencing and MALDI-TOF MS Biochemistry. Jun, 2009 | Pubmed ID: 19405523 Staphylococcal Vaccines and Immunotherapies Infectious Disease Clinics of North America. Mar, 2009 | Pubmed ID: 19135920 Defects in Innate Immunity Predispose C57BL/6J-Leprdb/Leprdb Mice to Infection by Staphylococcus Aureus Infection and Immunity. Mar, 2009 | Pubmed ID: 19103772 Antibodies to Capsular Polysaccharide and Clumping Factor A Prevent Mastitis and the Emergence of Unencapsulated and Small-colony Variants of Staphylococcus Aureus in Mice Infection and Immunity. Dec, 2008 | Pubmed ID: 18809660 Vaccination and Passive Immunisation Against Staphylococcus Aureus International Journal of Antimicrobial Agents. Nov, 2008 | Pubmed ID: 18757184 NorB, an Efflux Pump in Staphylococcus Aureus Strain MW2, Contributes to Bacterial Fitness in Abscesses Journal of Bacteriology. Nov, 2008 | Pubmed ID: 18723624 Intrafamilial Outbreak of Subcutaneous Abscesses Caused by PVL-positive Methicillin-sensitive Staphylococcus Aureus The Journal of Infection. Sep, 2008 | Pubmed ID: 18678412 IFN-gamma Regulated Chemokine Production Determines the Outcome of Staphylococcus Aureus Infection Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18606687 Comparison of Virulence in Community-associated Methicillin-resistant Staphylococcus Aureus Pulsotypes USA300 and USA400 in a Rat Model of Pneumonia The Journal of Infectious Diseases. Aug, 2008 | Pubmed ID: 18598194 Structural and Biological Characterization of a Capsular Polysaccharide Produced by Staphylococcus Haemolyticus Journal of Bacteriology. Mar, 2008 | Pubmed ID: 18165309 Capsular Polysaccharide Masks Clumping Factor A-mediated Adherence of Staphylococcus Aureus to Fibrinogen and Platelets The Journal of Infectious Diseases. Sep, 2007 | Pubmed ID: 17703424 CD4+ T Cells and CXC Chemokines Modulate the Pathogenesis of Staphylococcus Aureus Wound Infections Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006 | Pubmed ID: 16801559 Immunization with Staphylococcus Aureus Clumping Factor B, a Major Determinant in Nasal Carriage, Reduces Nasal Colonization in a Murine Model Infection and Immunity. Apr, 2006 | Pubmed ID: 16552044 Molecular Characterization of the Capsule Locus from Non-typeable Staphylococcus Aureus Molecular Microbiology. Feb, 2006 | Pubmed ID: 16420363 Capsule-negative Staphylococcus Aureus Induces Chronic Experimental Mastitis in Mice Infection and Immunity. Dec, 2005 | Pubmed ID: 16299284 Whole-genome Sequencing of Staphylococcus Haemolyticus Uncovers the Extreme Plasticity of Its Genome and the Evolution of Human-colonizing Staphylococcal Species Journal of Bacteriology. Nov, 2005 | Pubmed ID: 16237012 The Pathogenesis of Staphylococcus Aureus Infection in the Diabetic NOD Mouse Diabetes. Oct, 2005 | Pubmed ID: 16186391 Staphylococcus Aureus Strains That Express Serotype 5 or Serotype 8 Capsular Polysaccharides Differ in Virulence Infection and Immunity. Jun, 2005 | Pubmed ID: 15908379 Staphylococcus Aureus Capsular Polysaccharides Clinical Microbiology Reviews. Jan, 2004 | Pubmed ID: 14726462 Acute Tubular Necrosis in a Patient Receiving Tenofovir AIDS (London, England). Nov, 2003 | Pubmed ID: 14600530 Primary Sequence Characterization of Catestatin Intermediates and Peptides Defines Proteolytic Cleavage Sites Utilized for Converting Chromogranin a into Active Catestatin Secreted from Neuroendocrine Chromaffin Cells Biochemistry. Jun, 2003 | Pubmed ID: 12795588 Three Highly Conserved Proteins Catalyze the Conversion of UDP-N-acetyl-D-glucosamine to Precursors for the Biosynthesis of O Antigen in Pseudomonas Aeruginosa O11 and Capsule in Staphylococcus Aureus Type 5. Implications for the UDP-N-acetyl-L-fucosamine Biosynthetic Pathway The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12464616 Regulation of Staphylococcus Aureus Capsular Polysaccharide Expression by Agr and SarA Infection and Immunity. Feb, 2002 | Pubmed ID: 11796569 Development of Antistaphylococcal Vaccines Current Infectious Disease Reports. Dec, 2001 | Pubmed ID: 11722808 Stress-induced Antibiotic Susceptibility Testing on a Chip Maxim Kalashnikov1, Jennifer Campbell1, Jean C. Lee2, Andre Sharon1,3, Alexis F. Sauer-Budge1,4 1Fraunhofer USA Center for Manufacturing Innovation, 2Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 3Department of Mechanical Engineering, Boston University, 4Department of Biomedical Engineering, Boston University JoVE 50828 Bioengineering
Stress-induced Antibiotic Susceptibility Testing on a Chip Maxim Kalashnikov1, Jennifer Campbell1, Jean C. Lee2, Andre Sharon1,3, Alexis F. Sauer-Budge1,4 1Fraunhofer USA Center for Manufacturing Innovation, 2Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 3Department of Mechanical Engineering, Boston University, 4Department of Biomedical Engineering, Boston University JoVE 50828 Bioengineering
