In JoVE (1)

Other Publications (1)

Articles by Jerome V. Karpiak in JoVE

 JoVE Bioengineering

Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 2Biomedical Sciences Program, University of California, San Diego, 3Department of Bioengineering, University of California, San Diego

Other articles by Jerome V. Karpiak on PubMed

Density Gradient Multilayer Polymerization for Creating Complex Tissue

Advanced Materials (Deerfield Beach, Fla.). Mar, 2012  |  Pubmed ID: 22318771

An adaptable density gradient multilayer polymerization (DGMP) method facilitates simple fabrication of complex multicompartment scaffolds with structurally continuous interfaces. Solvent density liquid-liquid phase segregation compartmentalizes varied mechanical and chemical cues independently. Bulk photopolymerization produces stratified three-dimensional and two-dimensional matrices. Cells attach to patterned adhesion peptides on biomimetic 2D substrates.

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