Joey P. Granger Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center University of Mississippi Medical Center Biography Publications Institution JoVE Articles Joey P. Granger has not added a biography. If you are Joey P. Granger and would like to personalize this page please email our Author Liaison for assistance. Publications Nitric Oxide Synthase-mediated Blood Pressure Regulation in Obese Melanocortin-4 Receptor-deficient Pregnant Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2016 | Pubmed ID: 27534879 Differential Body Weight, Blood Pressure and Placental Inflammatory Responses to Normal Versus High-fat Diet in Melanocortin-4 Receptor-deficient Pregnant Rats Journal of Hypertension. Oct, 2016 | Pubmed ID: 27467764 Renal Intramedullary Infusion of Tempol Normalizes the Blood Pressure response to Intrarenal Blockade of Heme Oxygenase-1 In angiotensin II-dependent Hypertension Journal of the American Society of Hypertension : JASH. Apr, 2016 | Pubmed ID: 26922123 Placental Growth Factor Administration Abolishes Placental Ischemia-Induced Hypertension Hypertension (Dallas, Tex. : 1979). Apr, 2016 | Pubmed ID: 26831193 Sildenafil Treatment Ameliorates the Maternal Syndrome of Preeclampsia and Rescues Fetal Growth in the Dahl Salt-Sensitive Rat Hypertension (Dallas, Tex. : 1979). Mar, 2016 | Pubmed ID: 26729752 Preeclampsia and Pregnancy-Related Hypertensive Disorders Hypertension (Dallas, Tex. : 1979). Feb, 2016 | Pubmed ID: 26693822 Immune Mechanisms Linking Obesity and Preeclampsia Biomolecules. 2015 | Pubmed ID: 26569331 Increased Risk for the Development of Preeclampsia in Obese Pregnancies: Weighing in on the Mechanisms American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2015 | Pubmed ID: 26447211 Placental Ischemia-induced Increases in Brain Water Content and Cerebrovascular Permeability: Role of TNF-α American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2015 | Pubmed ID: 26400187 Heme Oxygenase Induction Attenuates TNF-α-induced Hypertension in Pregnant Rodents Frontiers in Pharmacology. 2015 | Pubmed ID: 26347650 Emerging Drugs for Preeclampsia--the Endothelium As a Target Expert Opinion on Emerging Drugs. 2015 | Pubmed ID: 26138471 Chronic Hyperleptinemia Results in the Development of Hypertension in Pregnant Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. May, 2015 | Pubmed ID: 25761697 Brain-mediated Antidiabetic, Anorexic, and Cardiovascular Actions of Leptin Require Melanocortin-4 Receptor Signaling Journal of Neurophysiology. Apr, 2015 | Pubmed ID: 25717164 Roles for the Sympathetic Nervous System, Renal Nerves, and CNS Melanocortin-4 Receptor in the Elevated Blood Pressure in Hyperandrogenemic Female Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2015 | Pubmed ID: 25695289 Inhalation of Carbon Monoxide is Ineffective As a Long-term Therapy to Reduce Obesity in Mice Fed a High Fat Diet BMC Obesity. 2014 | Pubmed ID: 26217498 Reduced Uterine Perfusion Pressure Induces Hypertension in the Pregnant Mouse American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2014 | Pubmed ID: 25298513 Placental Ischemia in Pregnant Rats Impairs Cerebral Blood Flow Autoregulation and Increases Blood-brain Barrier Permeability Physiological Reports. Aug, 2014 | Pubmed ID: 25168877 An Unusual Cause of Mineralocorticoid Hypertension Hypertension (Dallas, Tex. : 1979). Oct, 2014 | Pubmed ID: 25156173 Ouabain Inhibits Placental SFlt1 Production by Repressing HSP27-dependent HIF-1α Pathway FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2014 | Pubmed ID: 24970393 The Heme Oxygenases: Important Regulators of Pregnancy and Preeclampsia American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2014 | Pubmed ID: 24898840 Placental Ischemia Induces Changes in Gene Expression in Chorionic Tissue Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jun, 2014 | Pubmed ID: 24668059 Heme Oxygenase-1 Promotes Migration and β-epithelial Na+ Channel Expression in Cytotrophoblasts and Ischemic Placentas American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. May, 2014 | Pubmed ID: 24553299 Obese Melanocortin-4 Receptor-deficient Rats Exhibit Augmented Angiogenic Balance and Vasorelaxation During Pregnancy Physiological Reports. Sep, 2013 | Pubmed ID: 24159378 Euglycemic Hyperinsulinemia Increases Blood Pressure in Pregnant Rats Independent of Placental Antiangiogenic and Inflammatory Factors American Journal of Hypertension. Dec, 2013 | Pubmed ID: 23955606 Recent Advances in the Understanding of the Pathophysiology of Preeclampsia Hypertension (Dallas, Tex. : 1979). Oct, 2013 | Pubmed ID: 23897068 Sildenafil Attenuates Placental Ischemia-induced Hypertension American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2013 | Pubmed ID: 23785075 Heme Oxygenase Inhibition Increases Blood Pressure in Pregnant Rats American Journal of Hypertension. Jul, 2013 | Pubmed ID: 23553216 Heme Oxygenase in Pregnancy and Preeclampsia Current Opinion in Nephrology and Hypertension. Mar, 2013 | Pubmed ID: 23328500 Matrix Metalloproteinases As Drug Targets in Preeclampsia Current Drug Targets. Mar, 2013 | Pubmed ID: 23316964 Physiology's Impact: Discovering Life Physiology (Bethesda, Md.). Jan, 2013 | Pubmed ID: 23280351 Control of Soluble Fms-like Tyrosine-1 (sFlt-1) Production Response to Placental Ischemia/hypoxia: Role of Tumor Necrosis Factor-α American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jan, 2013 | Pubmed ID: 23193111 Hypertension: Physiology and Pathophysiology Comprehensive Physiology. Oct, 2012 | Pubmed ID: 23720252 Promoting Physiology As an Essential Element in Translational Research Physiology (Bethesda, Md.). Dec, 2012 | Pubmed ID: 23223625 Linking Placental Ischemia and Hypertension in Preeclampsia: Role of Endothelin 1 Hypertension (Dallas, Tex. : 1979). Aug, 2012 | Pubmed ID: 22566502 Bilirubin, Renal Hemodynamics, and Blood Pressure Frontiers in Pharmacology. 2012 | Pubmed ID: 22347861 Endothelin As a Final Common Pathway in the Pathophysiology of Preeclampsia: Therapeutic Implications Current Opinion in Nephrology and Hypertension. Mar, 2012 | Pubmed ID: 22257796 Heme Oxygenase-1 Attenuates Hypoxia-Induced SFlt-1 and Oxidative Stress in Placental Villi Through Its Metabolic Products CO and Bilirubin International Journal of Hypertension. 2012 | Pubmed ID: 22195275 L-arginine Supplementation Abolishes the Blood Pressure and Endothelin Response to Chronic Increases in Plasma SFlt-1 in Pregnant Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jan, 2012 | Pubmed ID: 22071155 Physiologists Without Borders Physiology (Bethesda, Md.). Dec, 2011 | Pubmed ID: 22170956 Placental Ischemia Impairs Middle Cerebral Artery Myogenic Responses in the Pregnant Rat Hypertension (Dallas, Tex. : 1979). Dec, 2011 | Pubmed ID: 22068864 Role of 20-hydroxyeicosatetraenoic Acid in Mediating Hypertension in Response to Chronic Renal Medullary Endothelin Type B Receptor Blockade PloS One. 2011 | Pubmed ID: 22016812 [The Heart During Pregnancy] Revista Española De Cardiología. Nov, 2011 | Pubmed ID: 21962953 Induction of Heme Oxygenase-1 Attenuates SFlt-1-induced Hypertension in Pregnant Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Nov, 2011 | Pubmed ID: 21865547 Endothelin: Key Mediator of Hypertension in Preeclampsia American Journal of Hypertension. Sep, 2011 | Pubmed ID: 21677700 Renal Medullary Endothelin-1 is Decreased in Dahl Salt-sensitive Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2011 | Pubmed ID: 21613578 84th President of APS Joey P. Granger The Physiologist. Apr, 2011 | Pubmed ID: 21560927 Changes in Cardiac Structure in Hypertension Produced by Placental Ischemia in Pregnant Rats: Effect of Tumor Necrosis Factor Blockade Journal of Hypertension. Jun, 2011 | Pubmed ID: 21505354 Mechanisms and Potential Therapies for Preeclampsia Current Hypertension Reports. Aug, 2011 | Pubmed ID: 21465139 Endothelin Type A Receptor Antagonist Attenuates Placental Ischemia-induced Hypertension and Uterine Vascular Resistance American Journal of Obstetrics and Gynecology. Apr, 2011 | Pubmed ID: 21458623 Induction of Heme Oxygenase 1 Attenuates Placental Ischemia-induced Hypertension Hypertension (Dallas, Tex. : 1979). May, 2011 | Pubmed ID: 21383306 Role of Reactive Oxygen Species During Hypertension in Response to Chronic Antiangiogenic Factor (sFlt-1) Excess in Pregnant Rats American Journal of Hypertension. Jan, 2011 | Pubmed ID: 20725052 Recent Insights into the Pathophysiology of Preeclampsia Expert Review of Obstetrics & Gynecology. Sep, 2010 | Pubmed ID: 21170149 Regulation of SFlt-1 and VEGF Secretion by Adenosine Under Hypoxic Conditions in Rat Placental Villous Explants American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2010 | Pubmed ID: 20962204 The Effect of Immune Factors, Tumor Necrosis Factor-alpha, and Agonistic Autoantibodies to the Angiotensin II Type I Receptor on Soluble Fms-like Tyrosine-1 and Soluble Endoglin Production in Response to Hypertension During Pregnancy American Journal of Hypertension. Aug, 2010 | Pubmed ID: 20431529 Role of Endothelin in Mediating Soluble Fms-like Tyrosine Kinase 1-induced Hypertension in Pregnant Rats Hypertension (Dallas, Tex. : 1979). Feb, 2010 | Pubmed ID: 20026766 Recombinant Vascular Endothelial Growth Factor 121 Infusion Lowers Blood Pressure and Improves Renal Function in Rats with Placentalischemia-induced Hypertension Hypertension (Dallas, Tex. : 1979). Feb, 2010 | Pubmed ID: 20026764 Effects of 17-hydroxyprogesterone on Tumor Necrosis Factor-alpha-induced Hypertension During Pregnancy American Journal of Hypertension. Oct, 2009 | Pubmed ID: 19745821 17-Hydroxyprogesterone Blunts the Hypertensive Response Associated with Reductions in Uterine Perfusion Pressure in Pregnant Rats American Journal of Obstetrics and Gynecology. Sep, 2009 | Pubmed ID: 19733289 Vascular Endothelial Growth Factor Inhibitors and Hypertension: a Central Role for the Kidney and Endothelial Factors? Hypertension (Dallas, Tex. : 1979). Sep, 2009 | Pubmed ID: 19652083 Effects of Hyperhomocysteinemia on Arterial Pressure and Nitric Oxide Production in Pregnant Rats American Journal of Hypertension. Oct, 2009 | Pubmed ID: 19629051 Inhibition of Bilirubin Metabolism Induces Moderate Hyperbilirubinemia and Attenuates ANG II-dependent Hypertension in Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2009 | Pubmed ID: 19571206 Angiotensin II Regulation of Renal Vascular ENaC Proteins American Journal of Hypertension. Jun, 2009 | Pubmed ID: 19325536 Oxidative Stress Contributes to Soluble Fms-like Tyrosine Kinase-1 Induced Vascular Dysfunction in Pregnant Rats American Journal of Hypertension. May, 2009 | Pubmed ID: 19265787 Hypertension Produced by Placental Ischemia in Pregnant Rats is Associated with Increased Soluble Endoglin Expression Hypertension (Dallas, Tex. : 1979). Feb, 2009 | Pubmed ID: 19075097 Hypertension in Response to Chronic Reductions in Uterine Perfusion in Pregnant Rats: Effect of Tumor Necrosis Factor-alpha Blockade Hypertension (Dallas, Tex. : 1979). Dec, 2008 | Pubmed ID: 18981324 Autoantibodies to the Angiotensin Type I Receptor in Response to Placental Ischemia and Tumor Necrosis Factor Alpha in Pregnant Rats Hypertension (Dallas, Tex. : 1979). Dec, 2008 | Pubmed ID: 18852381 Role of Reactive Oxygen Species in Hypertension Produced by Reduced Uterine Perfusion in Pregnant Rats American Journal of Hypertension. Oct, 2008 | Pubmed ID: 18670418 Pathophysiology of Hypertension in Response to Placental Ischemia During Pregnancy: a Central Role for Endothelin? Gender Medicine. 2008 | Pubmed ID: 18395679 Hypertension and Cardiovascular Disease in Women Hypertension (Dallas, Tex. : 1979). Apr, 2008 | Pubmed ID: 18356141 Recent Progress Toward the Understanding of the Pathophysiology of Hypertension During Preeclampsia Hypertension (Dallas, Tex. : 1979). Apr, 2008 | Pubmed ID: 18259004 ACE2 and ANG-(1-7) in the Gravid Uterus: the New Players on the Block American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2008 | Pubmed ID: 18199593 Pathophysiology of Hypertension During Preeclampsia: Linking Placental Ischemia with Endothelial Dysfunction American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2008 | Pubmed ID: 18055511 Dietary Salt Enhances Benzamil-sensitive Component of Myogenic Constriction in Mesenteric Arteries American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2008 | Pubmed ID: 18024548 Inflammatory Cytokines in the Pathophysiology of Hypertension During Preeclampsia Current Hypertension Reports. Dec, 2007 | Pubmed ID: 18367011 Role of Sex Steroids in Modulating Tumor Necrosis Factor Alpha-induced Changes in Vascular Function and Blood Pressure American Journal of Hypertension. Nov, 2007 | Pubmed ID: 17954370 Hypertension Produced by Reduced Uterine Perfusion in Pregnant Rats is Associated with Increased Soluble Fms-like Tyrosine Kinase-1 Expression Hypertension (Dallas, Tex. : 1979). Dec, 2007 | Pubmed ID: 17923588 Hypertension Produced by Reductions in Uterine Perfusion in the Pregnant Rat: Role of Interleukin 6 Hypertension (Dallas, Tex. : 1979). Oct, 2006 | Pubmed ID: 16940225 Endothelin, the Kidney, and Hypertension Current Hypertension Reports. Aug, 2006 | Pubmed ID: 16884660 Reduced Uterine Perfusion Pressure (RUPP) Model for Studying Cardiovascular-renal Dysfunction in Response to Placental Ischemia Methods in Molecular Medicine. 2006 | Pubmed ID: 16511995 An Emerging Role for Inflammatory Cytokines in Hypertension American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2006 | Pubmed ID: 16467462 Enhanced Endothelin Synthesis by Endothelial Cells Exposed to Sera from Pregnant Rats with Decreased Uterine Perfusion Hypertension (Dallas, Tex. : 1979). Mar, 2006 | Pubmed ID: 16391174 Testosterone Supplementation in Aging Men and Women: Possible Impact on Cardiovascular-renal Disease American Journal of Physiology. Renal Physiology. Nov, 2005 | Pubmed ID: 16210452 Hypertension Produced by Reductions in Uterine Perfusion in the Pregnant Rat: Role of Tumor Necrosis Factor-alpha Hypertension (Dallas, Tex. : 1979). Oct, 2005 | Pubmed ID: 16144982 Role of Endothelin in Mediating Tumor Necrosis Factor-induced Hypertension in Pregnant Rats Hypertension (Dallas, Tex. : 1979). Jul, 2005 | Pubmed ID: 15928030 Antisense Oligodeoxynucleotides Directed Against a Novel Angiotensinogen MRNA-stabilizing Protein Reduce Blood Pressure in Spontaneously Hypertensive Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2004 | Pubmed ID: 15155278 Inflammatory Cytokines, Vascular Function, and Hypertension American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jun, 2004 | Pubmed ID: 15142853 L-arginine Attenuates Hypertension in Pregnant Rats with Reduced Uterine Perfusion Pressure Hypertension (Dallas, Tex. : 1979). Apr, 2004 | Pubmed ID: 14769812 Cytochrome P-450 Inhibition Attenuates Hypertension Induced by Reductions in Uterine Perfusion Pressure in Pregnant Rats Hypertension (Dallas, Tex. : 1979). Mar, 2004 | Pubmed ID: 14757776 Role of Reactive Oxygen Species in Endothelin-induced Hypertension Hypertension (Dallas, Tex. : 1979). Oct, 2003 | Pubmed ID: 12874096 Endothelin American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2003 | Pubmed ID: 12855412 Evaluation of a Rat Model of Preeclampsia for HELLP Syndrome Characteristics Journal of the Society for Gynecologic Investigation. Apr, 2003 | Pubmed ID: 12699877 Endothelin-induced Increases in Ca2+ Entry Mechanisms of Vascular Contraction Are Enhanced During High-salt Diet Hypertension (Dallas, Tex. : 1979). Mar, 2003 | Pubmed ID: 12623997 Enhanced [Ca2+]i in Renal Arterial Smooth Muscle Cells of Pregnant Rats with Reduced Uterine Perfusion Pressure American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2003 | Pubmed ID: 12388289 Maternal and Fetal Adaptations During Pregnancy: Lessons in Regulatory and Integrative Physiology American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2002 | Pubmed ID: 12429557 Enhanced Thromboxane Synthesis During Chronic Reductions in Uterine Perfusion Pressure in Pregnant Rats American Journal of Hypertension. Sep, 2002 | Pubmed ID: 12219874 Pathophysiology of Preeclampsia: Linking Placental Ischemia/hypoxia with Microvascular Dysfunction Microcirculation (New York, N.Y. : 1994). Jul, 2002 | Pubmed ID: 12080413 TNF-alpha Enhances Contraction and Inhibits Endothelial NO-cGMP Relaxation in Systemic Vessels of Pregnant Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2002 | Pubmed ID: 12069938 Vascular Mechanisms of Increased Arterial Pressure in Preeclampsia: Lessons from Animal Models American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2002 | Pubmed ID: 12069928 Mechanisms of Pressure Natriuresis Current Hypertension Reports. Apr, 2002 | Pubmed ID: 11884271 Inducible Nitric Oxide Synthase Inhibition Attenuates Renal Hemodynamics During Pregnancy Hypertension (Dallas, Tex. : 1979). Feb, 2002 | Pubmed ID: 11882613 Low-salt Diet Enhances Vascular Reactivity and Ca(2+) Entry in Pregnant Rats with Normal and Reduced Uterine Perfusion Pressure Hypertension (Dallas, Tex. : 1979). Feb, 2002 | Pubmed ID: 11882575 Tumor Necrosis Factor-alpha-induced Hypertension in Pregnant Rats Results in Decreased Renal Neuronal Nitric Oxide Synthase Expression American Journal of Hypertension. Feb, 2002 | Pubmed ID: 11863253 Reduced Endothelial NO-cGMP Vascular Relaxation Pathway During TNF-alpha-induced Hypertension in Pregnant Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2002 | Pubmed ID: 11792648 Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart Bhavisha Bakrania1, Joey P. Granger1, Romain Harmancey1 1Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center, University of Mississippi Medical Center JoVE 54497 Biology
Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart Bhavisha Bakrania1, Joey P. Granger1, Romain Harmancey1 1Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center, University of Mississippi Medical Center JoVE 54497 Biology
