Translate this page to:
In JoVE (1)
Other Publications (1)
This translation into Russian was automatically generated.
English Version | Other Languages
Articles by Joshua D. Claunch in JoVE
Мониторинг Акупунктура Влияние на Мозга человека на МРТ
Kathleen K. S. Hui1, Vitaly Napadow1, Jing Liu1, Ming Li1, Ovidiu Marina1,2, Erika E. Nixon1, Joshua D. Claunch1, Lauren LaCount1, Tara Sporko1, Kenneth K. Kwong1
1Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 2William Beaumont Hospital
FMRI и физиологические мониторинга используется для изучения влияния акупунктуры на центральную и периферическую нервную системы. Акупунктура мобилизует лимбико-paralimbic-неокортекса сети, с большим перекрытием с сетевой режим по умолчанию, для модуляции неврологических деятельности, возможно, связано с его вегетативной эффект в периферической нервной системе.
Other articles by Joshua D. Claunch on PubMed
Brain Research. Sep, 2009 | Pubmed ID: 19559684
Previous work has shown that acupuncture stimulation evokes deactivation of a limbic-paralimbic-neocortical network (LPNN) as well as activation of somatosensory brain regions. This study explores the activity and functional connectivity of these regions during acupuncture vs. tactile stimulation and vs. acupuncture associated with inadvertent sharp pain. Acupuncture during 201 scans and tactile stimulation during 74 scans for comparison at acupoints LI4, ST36 and LV3 was monitored with fMRI and psychophysical response in 48 healthy subjects. Clusters of deactivated regions in the medial prefrontal, medial parietal and medial temporal lobes as well as activated regions in the sensorimotor and a few paralimbic structures can be identified during acupuncture by general linear model analysis and seed-based cross correlation analysis. Importantly, these clusters showed virtual identity with the default mode network and the anti-correlated task-positive network in response to stimulation. In addition, the amygdala and hypothalamus, structures not routinely reported in the default mode literature, were frequently involved in acupuncture. When acupuncture induced sharp pain, the deactivation was attenuated or became activated instead. Tactile stimulation induced greater activation of the somatosensory regions but less extensive deactivation of the LPNN. These results indicate that the deactivation of the LPNN during acupuncture cannot be completely explained by the demand of attention that is commonly proposed in the default mode literature. Our results suggest that acupuncture mobilizes the anti-correlated functional networks of the brain to mediate its actions, and that the effect is dependent on the psychophysical response.