JoVE General
Cliff A. Megerian, Chris Heddon, Sami Melki, Suhael Momin, Janis Paulsey, Joy Obokhare, Kumar Alagramam
Otolaryngology - Head and Neck Surgery, Case Western Reserve University
This video shows how to surgically obstruct the guinea pig's endolymphatic duct to produce endolymphatic hydrops.
Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. Dec, 2011 | Pubmed ID: 22015942
Interruption of the excitotoxic and inflammatory pathways implicated in endolymphatic hydrops (ELH)-associated hearing loss (HL) should afford hearing protection at the neuronal level.