Katalin Kariko Department of Neurosurgery School of Medicine, University of Pennsylvania Biography Publications Institution JoVE Articles Katalin Kariko has not added a biography. If you are Katalin Kariko and would like to personalize this page please email our Author Liaison for assistance. Publications Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing MRNA Encoding Erythropoietin Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2012 | Pubmed ID: 22334017 Toll-like Receptor 4 Contributes to Poor Outcome After Intracerebral Hemorrhage Annals of Neurology. Oct, 2011 | Pubmed ID: 22028224 Generating the Optimal MRNA for Therapy: HPLC Purification Eliminates Immune Activation and Improves Translation of Nucleoside-modified, Protein-encoding MRNA Nucleic Acids Research. Nov, 2011 | Pubmed ID: 21890902 Nucleoside Modifications in RNA Limit Activation of 2'-5'-oligoadenylate Synthetase and Increase Resistance to Cleavage by RNase L Nucleic Acids Research. Nov, 2011 | Pubmed ID: 21813458 Neutrophil Depletion Diminishes Monocyte Infiltration and Improves Functional Outcome After Experimental Intracerebral Hemorrhage Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725751 DICER1 Deficit Induces Alu RNA Toxicity in Age-related Macular Degeneration Nature. Mar, 2011 | Pubmed ID: 21297615 Incorporation of Pseudouridine into MRNA Enhances Translation by Diminishing PKR Activation Nucleic Acids Research. Sep, 2010 | Pubmed ID: 20457754 Incorporation of Pseudouridine into MRNA Yields Superior Nonimmunogenic Vector with Increased Translational Capacity and Biological Stability Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2008 | Pubmed ID: 18797453 Sequence- and Target-independent Angiogenesis Suppression by SiRNA Via TLR3 Nature. Apr, 2008 | Pubmed ID: 18368052 Naturally Occurring Nucleoside Modifications Suppress the Immunostimulatory Activity of RNA: Implication for Therapeutic RNA Development Current Opinion in Drug Discovery & Development. Sep, 2007 | Pubmed ID: 17786850 Gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission Journal of Immunology (Baltimore, Md. : 1950). Sep, 2007 | Pubmed ID: 17709527 Cerebral Preconditioning Using Cortical Application of Hypertonic Salt Solutions: Upregulation of MRNAs Encoding Inhibitors of Inflammation Brain Research. Jun, 2006 | Pubmed ID: 16725117 Suppression of RNA Recognition by Toll-like Receptors: the Impact of Nucleoside Modification and the Evolutionary Origin of RNA Immunity. Aug, 2005 | Pubmed ID: 16111635 Inhibition of Toll-like Receptor and Cytokine Signaling--a Unifying Theme in Ischemic Tolerance Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Nov, 2004 | Pubmed ID: 15545925 Induction of Tolerance to Focal Ischemia in Rat Brain: Dissociation Between Cortical Lesioning and Spreading Depression Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Oct, 2004 | Pubmed ID: 15529017 Exogenous SiRNA Mediates Sequence-independent Gene Suppression by Signaling Through Toll-like Receptor 3 Cells, Tissues, Organs. 2004 | Pubmed ID: 15388987 Short Interfering RNA-mediated Inhibition of Herpes Simplex Virus Type 1 Gene Expression and Function During Infection of Human Keratinocytes Journal of Virology. Oct, 2004 | Pubmed ID: 15367593 Small Interfering RNAs Mediate Sequence-independent Gene Suppression and Induce Immune Activation by Signaling Through Toll-like Receptor 3 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15153468 Cutting Edge: Innate Immune System Discriminates Between RNA Containing Bacterial Versus Eukaryotic Structural Features That Prime for High-level IL-12 Secretion by Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Apr, 2004 | Pubmed ID: 15034009 MRNA is an Endogenous Ligand for Toll-like Receptor 3 The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14729660 Inhibition of HIV-1 Infection by Small Interfering RNA-mediated RNA Interference Journal of Immunology (Baltimore, Md. : 1950). Nov, 2002 | Pubmed ID: 12391237 Platelet Factor 4 Binds to Low-density Lipoprotein Receptors and Disrupts the Endocytic Machinery, Resulting in Retention of Low-density Lipoprotein on the Cell Surface Blood. May, 2002 | Pubmed ID: 11986215 Extracellular MRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-alpha Secretion and Signaling Through a Nucleotide Receptor The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11821398 Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice Lauren H. Sansing1,2,3, Scott E. Kasner2, Louise McCullough1, Puneet Agarwal2, Frank A. Welsh4, Katalin Kariko4 1Department of Neurology, University of Connecticut Health Center, 2Department of Neurology, School of Medicine, University of Pennsylvania, 3Department of Neurosurgery, Hartford Hospital, 4Department of Neurosurgery, School of Medicine, University of Pennsylvania JoVE 2618 Neuroscience
Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice Lauren H. Sansing1,2,3, Scott E. Kasner2, Louise McCullough1, Puneet Agarwal2, Frank A. Welsh4, Katalin Kariko4 1Department of Neurology, University of Connecticut Health Center, 2Department of Neurology, School of Medicine, University of Pennsylvania, 3Department of Neurosurgery, Hartford Hospital, 4Department of Neurosurgery, School of Medicine, University of Pennsylvania JoVE 2618 Neuroscience
