Klearchos K. Papas Surgery University of Arizona Biography Publications Institution JoVE Articles Klearchos K. Papas has not added a biography. If you are Klearchos K. Papas and would like to personalize this page please email our Author Liaison for assistance. Publications Plasticity and Aggregation of Juvenile Porcine Islets in Modified Culture: Preliminary Observations Cell Transplantation. Apr, 2016 | Pubmed ID: 27109912 Effect of Oxygen Supply on the Size of Implantable Islet-containing Encapsulation Devices Panminerva Medica. Mar, 2016 | Pubmed ID: 26837777 Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation PloS One. 2015 | Pubmed ID: 26258815 Temperature Profiles of Different Cooling Methods in Porcine Pancreas Procurement Xenotransplantation. Nov-Dec, 2014 | Pubmed ID: 25040217 Magnetic Resonance Imaging: a Tool to Monitor and Optimize Enzyme Distribution During Porcine Pancreas Distention for Islet Isolation Xenotransplantation. Sep-Oct, 2014 | Pubmed ID: 24986758 Regulation of the JNK3 Signaling Pathway During Islet Isolation: JNK3 and C-fos As New Markers of Islet Quality for Transplantation PloS One. 2014 | Pubmed ID: 24983249 Intraportal Islet Oxygenation Journal of Diabetes Science and Technology. May, 2014 | Pubmed ID: 24876622 Function and Expression of Sulfonylurea, Adrenergic, and Glucagon-like Peptide 1 Receptors in Isolated Porcine Islets Xenotransplantation. Jul-Aug, 2014 | Pubmed ID: 24801676 Maintenance of Ischemic β Cell Viability Through Delivery of Lipids and ATP by Targeted Liposomes Biomaterials Science. Apr, 2014 | Pubmed ID: 24653833 Islet Size Index As a Predictor of Outcomes in Clinical Islet Autotransplantation Transplantation. Jun, 2014 | Pubmed ID: 24621532 Nutrient Regulation by Continuous Feeding Removes Limitations on Cell Yield in the Large-scale Expansion of Mammalian Cell Spheroids PloS One. 2013 | Pubmed ID: 24204645 Manufacturing Porcine Islets: Culture at 22 °C Has No Advantage Above Culture at 37 °C: a Gene Expression Evaluation Xenotransplantation. Nov-Dec, 2013 | Pubmed ID: 23941232 Factors Affecting Transplant Outcomes in Diabetic Nude Mice Receiving Human, Porcine, and Nonhuman Primate Islets: Analysis of 335 Transplantations Transplantation. Jun, 2013 | Pubmed ID: 23677052 Persufflation (gaseous Oxygen Perfusion) As a Method of Heart Preservation Journal of Cardiothoracic Surgery. 2013 | Pubmed ID: 23607734 Differences in Glucose-stimulated Insulin Secretion in Vitro of Islets from Human, Nonhuman Primate, and Porcine Origin Xenotransplantation. Mar-Apr, 2013 | Pubmed ID: 23384163 International Workshop: Islet Transplantation Without Borders Enabling Islet Transplantation in Greece with International Collaboration and Innovative Technology Clinical Transplantation. Mar, 2013 | Pubmed ID: 23330863 Standardized Transportation of Human Islets: an Islet Cell Resource Center Study of More Than 2,000 Shipments Cell Transplantation. 2013 | Pubmed ID: 22889479 Real-time Assessment of Encapsulated Neonatal Porcine Islets Prior to Clinical Xenotransplantation Xenotransplantation. Nov-Dec, 2012 | Pubmed ID: 23088180 Supplements in Human Islet Culture: Human Serum Albumin is Inferior to Fetal Bovine Serum Cell Transplantation. 2012 | Pubmed ID: 22863057 Energetic Recovery in Porcine Grafts by Minimally Invasive Liver Oxygenation The Journal of Surgical Research. Dec, 2012 | Pubmed ID: 22445459 A New Enzyme Mixture to Increase the Yield and Transplant Rate of Autologous and Allogeneic Human Islet Products Transplantation. Apr, 2012 | Pubmed ID: 22318245 Persufflation (or Gaseous Oxygen Perfusion) As a Method of Organ Preservation Cryobiology. Jan, 2012 | Pubmed ID: 22301419 Species Incompatibilities in the Pig-to-macaque Islet Xenotransplant Model Affect Transplant Outcome: a Comparison with Allotransplantation Xenotransplantation. Nov-Dec, 2011 | Pubmed ID: 22168140 Insulin Degradation by Acinar Cell Proteases Creates a Dysfunctional Environment for Human Islets Before/after Transplantation: Benefits of α-1 Antitrypsin Treatment Transplantation. Dec, 2011 | Pubmed ID: 22089666 Rates of Insulin Secretion in INS-1 Cells Are Enhanced by Coupling to Anaplerosis and Kreb's Cycle Flux Independent of ATP Synthesis Biochemical and Biophysical Research Communications. Nov, 2011 | Pubmed ID: 22008547 Successful Isolation and Transplantation of Nonhuman Primate Islets Using a Novel Purified Enzyme Blend Transplantation. Oct, 2011 | Pubmed ID: 21989272 Paramagnetic Microparticles Do Not Elicit Islet Cytotoxicity with Co-culture or Host Immune Reactivity After Implantation Xenotransplantation. Jul-Aug, 2011 | Pubmed ID: 21848541 Microbiological Safety of Porcine Islets: Comparison with Source Pig Xenotransplantation. Mar-Apr, 2011 | Pubmed ID: 21496116 Application of Magnetic Particle Tracking Velocimetry to Quadrupole Magnetic Sorting of Porcine Pancreatic Islets Biotechnology and Bioengineering. Sep, 2011 | Pubmed ID: 21495008 Silica-nanoparticle Coatings by Adsorption from Lysine-silica-nanoparticle Sols on Inorganic and Biological Surfaces Angewandte Chemie (International Ed. in English). Feb, 2011 | Pubmed ID: 21308917 Prediction of Pancreatic Tissue Densities by an Analytical Test Gradient System Before Purification Maximizes Human Islet Recovery for Islet Autotransplantation/allotransplantation Transplantation. Mar, 2011 | Pubmed ID: 21169878 Binding of the Fibronectin-mimetic Peptide, PR_b, to Alpha5beta1 on Pig Islet Cells Increases Fibronectin Production and Facilitates Internalization of PR_b Functionalized Liposomes Langmuir : the ACS Journal of Surfaces and Colloids. Sep, 2010 | Pubmed ID: 20704278 Enumeration of Islets by Nuclei Counting and Light Microscopic Analysis Laboratory Investigation; a Journal of Technical Methods and Pathology. Nov, 2010 | Pubmed ID: 20697375 Successful Human Islet Isolation and Transplantation Indicating the Importance of Class 1 Collagenase and Collagen Degradation Activity Assay Transplantation. Apr, 2010 | Pubmed ID: 20300051 Prediction of Marginal Mass Required for Successful Islet Transplantation Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. Feb, 2010 | Pubmed ID: 20233002 Islet Assessment for Transplantation Current Opinion in Organ Transplantation. Dec, 2009 | Pubmed ID: 19812494 Quadrupole Magnetic Sorting of Porcine Islets of Langerhans Tissue Engineering. Part C, Methods. Jun, 2009 | Pubmed ID: 19505179 Effects of Energy Dissipation Rate on Islets of Langerhans: Implications for Isolation and Transplantation Biotechnology and Bioengineering. Jun, 2009 | Pubmed ID: 19191351 Limitations in the Use of Fluorescein Diacetate/Propidium Iodide (FDA/PI) and Cell Permeable Nucleic Acid Stains for Viability Measurements of Isolated Islets of Langerhans Current Trends in Biotechnology and Pharmacy. Mar, 2008 | Pubmed ID: 20814586 Pig Pancreas Anatomy: Implications for Pancreas Procurement, Preservation, and Islet Isolation Transplantation. Dec, 2008 | Pubmed ID: 19077881 Pancreas Preservation for Pancreas and Islet Transplantation Current Opinion in Organ Transplantation. Aug, 2008 | Pubmed ID: 18685343 Pancreas Preservation for Pancreas and Islet Transplantation Current Opinion in Organ Transplantation. Apr, 2008 | Pubmed ID: 18685293 A Stirred Microchamber for Oxygen Consumption Rate Measurements with Pancreatic Islets Biotechnology and Bioengineering. Dec, 2007 | Pubmed ID: 17497731 The Rat Pancreas is Not an Appropriate Model for Testing the Preservation of the Human Pancreas with the Two-layer Method Transplantation. May, 2006 | Pubmed ID: 16732188 13C NMR Isotopomer Analysis of Anaplerotic Pathways in INS-1 Cells The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15304488 Nutrient Regulation by Continuous Feeding for Large-scale Expansion of Mammalian Cells in Spheroids Bradley P. Weegman1, Ahmad Essawy2, Peter Nash2, Alexandra L. Carlson2, Kristin J. Voltzke3, Zhaohui Geng2, Marjan Jahani2, Benjamin B. Becker2, Klearchos K. Papas4, Meri T. Firpo2 1Radiology, University of Minnesota, 2Medicine, University of Minnesota, 3School of Public Health, University of Minnesota, 4Surgery, University of Arizona JoVE 52224 Bioengineering
Nutrient Regulation by Continuous Feeding for Large-scale Expansion of Mammalian Cells in Spheroids Bradley P. Weegman1, Ahmad Essawy2, Peter Nash2, Alexandra L. Carlson2, Kristin J. Voltzke3, Zhaohui Geng2, Marjan Jahani2, Benjamin B. Becker2, Klearchos K. Papas4, Meri T. Firpo2 1Radiology, University of Minnesota, 2Medicine, University of Minnesota, 3School of Public Health, University of Minnesota, 4Surgery, University of Arizona JoVE 52224 Bioengineering
