Leonard H. Augenlicht

Publications

• Vitamin D is a Determinant of Mouse Intestinal Lgr5 Stem Cell Functions
  Carcinogenesis. Oct, 2014  |   Pubmed ID: 25344836
• The Intestinal Epithelial Cell Differentiation Marker Intestinal Alkaline Phosphatase (ALPi) is Selectively Induced by Histone Deacetylase Inhibitors (HDACi) in Colon Cancer Cells in a Kruppel-like Factor 5 (KLF5)-dependent Manner
  The Journal of Biological Chemistry. Sep, 2014  |   Pubmed ID: 25037223
• Circulating Soluble Cytokine Receptors and Colorectal Cancer Risk
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2014  |   Pubmed ID: 24192010
• Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals
  Science (New York, N.Y.). Oct, 2013  |   Pubmed ID: 24072822
• The Effect of Lung Cancer on Cytokine Expression in Peripheral Blood Mononuclear Cells
  PloS One. 2013  |   Pubmed ID: 23762239
• Abdominal Obesity, Independent from Caloric Intake, Accounts for the Development of Intestinal Tumors in Apc(1638N/+) Female Mice
  Cancer Prevention Research (Philadelphia, Pa.). Mar, 2013  |   Pubmed ID: 23466815
• Dietary Cholecalciferol and Calcium Levels in a Western-style Defined Rodent Diet Alter Energy Metabolism and Inflammatory Responses in Mice
  The Journal of Nutrition. May, 2012  |   Pubmed ID: 22437564
• Intrinsic Mitochondrial Membrane Potential and Associated Tumor Phenotype Are Independent of MUC1 Over-expression
  PloS One. 2011  |   Pubmed ID: 21966455
• Intestinal Epithelial-specific PTEN Inactivation Results in Tumor Formation
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Nov, 2011  |   Pubmed ID: 21836055
• Stable Differences in Intrinsic Mitochondrial Membrane Potential of Tumor Cell Subpopulations Reflect Phenotypic Heterogeneity
  International Journal of Cell Biology. 2011  |   Pubmed ID: 21760799
• Mybl2, Downregulated During Colon Epithelial Cell Maturation, is Suppressed by MiR-365
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Sep, 2011  |   Pubmed ID: 21737779
• Paneth Cell Marker Expression in Intestinal Villi and Colon Crypts Characterizes Dietary Induced Risk for Mouse Sporadic Intestinal Cancer
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011  |   Pubmed ID: 21652773
• MYBL2, a Link Between Proliferation and Differentiation in Maturing Colon Epithelial Cells
  Journal of Cellular Physiology. Mar, 2011  |   Pubmed ID: 20857481
• Transcriptional Attenuation in Colon Carcinoma Cells in Response to Butyrate
  Cancer Prevention Research (Philadelphia, Pa.). Oct, 2010  |   Pubmed ID: 20841488
• Prediction and Testing of Biological Networks Underlying Intestinal Cancer
  PloS One. 2010  |   Pubmed ID: 20824133
• Oxaliplatin Resistance Induced by ERCC1 Up-regulation is Abrogated by SiRNA-mediated Gene Silencing in Human Colorectal Cancer Cells
  Anticancer Research. Jul, 2010  |   Pubmed ID: 20682979
• Altered Dynamics of Intestinal Cell Maturation in Apc1638N/+ Mice
  Cancer Research. Jul, 2010  |   Pubmed ID: 20570902
• Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors is Mediated by an Sp1/Sp3-activated Transcriptional Program Involving Immediate-early Gene Induction
  Cancer Research. Jan, 2010  |   Pubmed ID: 20068171
• Gene Expression Profiling of Primary and Metastatic Colon Cancers Identifies a Reduced Proliferative Rate in Metastatic Tumors
  Clinical & Experimental Metastasis. 2010  |   Pubmed ID: 19882219
• An A13 Repeat Within the 3'-untranslated Region of Epidermal Growth Factor Receptor (EGFR) is Frequently Mutated in Microsatellite Instability Colon Cancers and is Associated with Increased EGFR Expression
  Cancer Research. Oct, 2009  |   Pubmed ID: 19789347
• PKCalpha Tumor Suppression in the Intestine is Associated with Transcriptional and Translational Inhibition of Cyclin D1
  Experimental Cell Research. May, 2009  |   Pubmed ID: 19232344
• Butyrate and Vitamin D3 Induce Transcriptional Attenuation at the Cyclin D1 Locus in Colonic Carcinoma Cells
  Journal of Cellular Physiology. Mar, 2009  |   Pubmed ID: 19034928
• Western-style Diet-induced Colonic Tumors and Their Modulation by Calcium and Vitamin D in C57Bl/6 Mice: a Preclinical Model for Human Sporadic Colon Cancer
  Carcinogenesis. Jan, 2009  |   Pubmed ID: 19017685
• Proteomic Changes During Intestinal Cell Maturation in Vivo
  Journal of Proteomics. Dec, 2008  |   Pubmed ID: 18824147
• HDAC4 Promotes Growth of Colon Cancer Cells Via Repression of P21
  Molecular Biology of the Cell. Oct, 2008  |   Pubmed ID: 18632985
• Intestinal Deletion of Pofut1 in the Mouse Inactivates Notch Signaling and Causes Enterocolitis
  Gastroenterology. Sep, 2008  |   Pubmed ID: 18621050
• Single-cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
  Cancer Research. Jul, 2008  |   Pubmed ID: 18593893
• Genetic Deficiency of Decorin Causes Intestinal Tumor Formation Through Disruption of Intestinal Cell Maturation
  Carcinogenesis. Jul, 2008  |   Pubmed ID: 18550571
• Expression of Selenium-binding Protein 1 Characterizes Intestinal Cell Maturation and Predicts Survival for Patients with Colorectal Cancer
  Molecular Nutrition & Food Research. Nov, 2008  |   Pubmed ID: 18435490
• PIK3CA Mutation/PTEN Expression Status Predicts Response of Colon Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Cetuximab
  Cancer Research. Mar, 2008  |   Pubmed ID: 18339877
• Sulindac Suppresses Beta-catenin Expression in Human Cancer Cells
  European Journal of Pharmacology. Mar, 2008  |   Pubmed ID: 18291362
• P27kip1 Regulates Cdk2 Activity in the Proliferating Zone of the Mouse Intestinal Epithelium: Potential Role in Neoplasia
  Gastroenterology. Jul, 2007  |   Pubmed ID: 17631145
• C-Jun NH2-terminal Kinase 1 Plays a Critical Role in Intestinal Homeostasis and Tumor Suppression
  The American Journal of Pathology. Jul, 2007  |   Pubmed ID: 17591974
• Drug-induced Inactivation or Gene Silencing of Class I Histone Deacetylases Suppresses Ovarian Cancer Cell Growth: Implications for Therapy
  Cancer Biology & Therapy. May, 2007  |   Pubmed ID: 17387270
• JNK1 is Required for Sulindac-mediated Inhibition of Cell Proliferation and Induction of Apoptosis in Vitro and in Vivo
  European Journal of Pharmacology. Apr, 2007  |   Pubmed ID: 17292881
• Interaction of Genetic and Dietary Factors in Mouse Intestinal Tumorigenesis
  The Journal of Nutrition. Oct, 2006  |   Pubmed ID: 16988154
• Na(+)/monocarboxylate Transport (SMCT) Protein Expression Correlates with Survival in Colon Cancer: Molecular Characterization of SMCT
  Proceedings of the National Academy of Sciences of the United States of America. May, 2006  |   Pubmed ID: 16670197
• Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and P21 Expression and Are Deregulated in Human Colon Cancer
  The Journal of Biological Chemistry. May, 2006  |   Pubmed ID: 16533812
• Growth Properties of Colonic Tumor Cells Are a Function of the Intrinsic Mitochondrial Membrane Potential
  Cancer Research. Feb, 2006  |   Pubmed ID: 16452217
• Kaiso-deficient Mice Show Resistance to Intestinal Cancer
  Molecular and Cellular Biology. Jan, 2006  |   Pubmed ID: 16354691
• Pathways in Nutritional Modulation of Homeostasis and Tumorigenesis
  The Journal of Nutrition. Dec, 2005  |   Pubmed ID: 16317165
• The Intrinsic Mitochondrial Membrane Potential of Colonic Carcinoma Cells is Linked to the Probability of Tumor Progression
  Cancer Research. Nov, 2005  |   Pubmed ID: 16267009
• P27kip1 in Intestinal Tumorigenesis and Chemoprevention in the Mouse
  Cancer Research. Oct, 2005  |   Pubmed ID: 16230399
• Gene Expression Profiling of Intestinal Epithelial Cell Maturation Along the Crypt-villus Axis
  Gastroenterology. Apr, 2005  |   Pubmed ID: 15825089
• Inactivation of P21WAF1/cip1 Enhances Intestinal Tumor Formation in Muc2-/- Mice
  The American Journal of Pathology. Apr, 2005  |   Pubmed ID: 15793302
• Methylation in the P21WAF1/cip1 Promoter of Apc+/-, P21+/- Mice and Lack of Response to Sulindac
  Oncogene. Mar, 2005  |   Pubmed ID: 15688007
• Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice
  Molecular and Cellular Biology. Sep, 2004  |   Pubmed ID: 15314168
• Customizing Chemotherapy for Colon Cancer: the Potential of Gene Expression Profiling
  Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. Jun, 2004  |   Pubmed ID: 15296862
• Tumor Necrosis Factor-alpha Related Gene Response to Epothilone B in Ovarian Cancer
  Gynecologic Oncology. Apr, 2004  |   Pubmed ID: 15047209
• Gene Expression Profiling-based Prediction of Response of Colon Carcinoma Cells to 5-fluorouracil and Camptothecin
  Cancer Research. Dec, 2003  |   Pubmed ID: 14695196
• Spontaneous Aberrant Crypt Foci in Apc1638N Mice with a Mutant Apc Allele
  The American Journal of Pathology. Nov, 2003  |   Pubmed ID: 14578176
• The Intrinsic Mitochondrial Membrane Potential (Deltapsim) is Associated with Steady-state Mitochondrial Activity and the Extent to Which Colonic Epithelial Cells Undergo Butyrate-mediated Growth Arrest and Apoptosis
  Cancer Research. Oct, 2003  |   Pubmed ID: 14559818
• TR3/Nur77 in Colon Cancer Cell Apoptosis
  Cancer Research. Sep, 2003  |   Pubmed ID: 14500374
• Targeted Inactivation of P27kip1 is Sufficient for Large and Small Intestinal Tumorigenesis in the Mouse, Which Can Be Augmented by a Western-style High-risk Diet
  Cancer Research. Aug, 2003  |   Pubmed ID: 12941825
• Gamma Delta T Cells Provide an Early Source of Interferon Gamma in Tumor Immunity
  The Journal of Experimental Medicine. Aug, 2003  |   Pubmed ID: 12900519
• Application of Gene Expression Profiling to Colon Cell Maturation, Transformation and Chemoprevention
  The Journal of Nutrition. Jul, 2003  |   Pubmed ID: 12840217
• Microarray Analysis in the Clinical Management of Cancer
  Hematology/oncology Clinics of North America. Apr, 2003  |   Pubmed ID: 12737394
• Environment-gene Interactions in Intestinal Cancer
  European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). Aug, 2002  |   Pubmed ID: 12570330
• Short Chain Fatty Acids and Colon Cancer
  The Journal of Nutrition. Dec, 2002  |   Pubmed ID: 12468628
• Novel Detection and Differential Utilization of a C-myc Transcriptional Block in Colon Cancer Chemoprevention
  Cancer Research. Nov, 2002  |   Pubmed ID: 12414619
• A Gene Expression Profile That Defines Colon Cell Maturation in Vitro
  Cancer Research. Aug, 2002  |   Pubmed ID: 12183439
• Cell Type- and Promoter-dependent Modulation of the Wnt Signaling Pathway by Sodium Butyrate
  International Journal of Cancer. Journal International Du Cancer. Jan, 2002  |   Pubmed ID: 11774242