Lynne S. Cox Department of Biochemistry University of Oxford Biography Publications Institution JoVE Articles Lynne S. Cox has not added a biography. If you are Lynne S. Cox and would like to personalize this page please email our Author Liaison for assistance. Publications The Drosophila Orthologue of Progeroid Human WRN Exonuclease, DmWRNexo, Cleaves Replication Substrates but is Inhibited by Uracil or Abasic Sites : Analysis of DmWRNexo Activity in Vitro Age (Dordrecht, Netherlands). Jun, 2013 | Pubmed ID: 22562358 The Role of DNA Exonucleases in Protecting Genome Stability and Their Impact on Ageing Age (Dordrecht, Netherlands). Dec, 2012 | Pubmed ID: 21948156 Recapitulation of Werner Syndrome Sensitivity to Camptothecin by Limited Knockdown of the WRN Helicase/exonuclease Biogerontology. Feb, 2012 | Pubmed ID: 21786128 Prospects for Rejuvenation of Aged Tissue by Telomerase Reactivation Rejuvenation Research. Dec, 2010 | Pubmed ID: 21226558 Live Fast, Die Young: New Lessons in Mammalian Longevity Rejuvenation Research. Aug, 2009 | Pubmed ID: 19725776 Increasing Longevity Through Caloric Restriction or Rapamycin Feeding in Mammals: Common Mechanisms for Common Outcomes? Aging Cell. Sep, 2009 | Pubmed ID: 19678809 Cell Senescence: the Future of Ageing? Biogerontology. Jun, 2009 | Pubmed ID: 19115080 DmWRNexo is a 3'-5' Exonuclease: Phenotypic and Biochemical Characterization of Mutants of the Drosophila Orthologue of Human WRN Exonuclease Biogerontology. Jun, 2009 | Pubmed ID: 18956248 Identification and Characterization of a Drosophila Ortholog of WRN Exonuclease That is Required to Maintain Genome Integrity Aging Cell. Jun, 2008 | Pubmed ID: 18346216 Modeling Werner Syndrome in Drosophila Melanogaster: Hyper-recombination in Flies Lacking WRN-like Exonuclease Annals of the New York Academy of Sciences. Nov, 2007 | Pubmed ID: 18056975 Correction of Proliferation and Drug Sensitivity Defects in the Progeroid Werner's Syndrome by Holliday Junction Resolution Rejuvenation Research. Mar, 2007 | Pubmed ID: 17378750 Distinct Pools of Proliferating Cell Nuclear Antigen Associated to DNA Replication Sites Interact with the P125 Subunit of DNA Polymerase Delta or DNA Ligase I Experimental Cell Research. Feb, 2004 | Pubmed ID: 14729473 Characterisation of the Interaction Between WRN, the Helicase/exonuclease Defective in Progeroid Werner's Syndrome, and an Essential Replication Factor, PCNA Mechanisms of Ageing and Development. Feb, 2003 | Pubmed ID: 12633936 Characterisation of a Sexual Stage-specific Gene Encoding ORC1 Homologue in the Human Malaria Parasite Plasmodium Falciparum Parasitology International. Mar, 2003 | Pubmed ID: 12543146 Asymmetry of DNA Replication Fork Progression in Werner's Syndrome Aging Cell. Oct, 2002 | Pubmed ID: 12882351 Identification of a Second Proliferating Cell Nuclear Antigen in the Human Malarial Pathogen Plasmodium Falciparum International Journal for Parasitology. Dec, 2002 | Pubmed ID: 12464414 A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases Penelope A. Mason1, Ivan Boubriak1, Lynne S. Cox1 1Department of Biochemistry, University of Oxford JoVE 50722 Biology
A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases Penelope A. Mason1, Ivan Boubriak1, Lynne S. Cox1 1Department of Biochemistry, University of Oxford JoVE 50722 Biology
