Mark Van de Casteele

Publications

• Estrogen Receptor α Regulates Beta Cell Formation During Pancreas Development and Following Injury
  Diabetes. May, 2015  |   Pubmed ID: 26015547
• Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β-Cell Development, Injury, and Regeneration
  Stem Cells Translational Medicine. Jun, 2015  |   Pubmed ID: 25848123
• Macrophage Dynamics Are Regulated by Local Macrophage Proliferation and Monocyte Recruitment in Injured Pancreas
  European Journal of Immunology. May, 2015  |   Pubmed ID: 25645754
• Partial Duct Ligation: β-cell Proliferation and Beyond
  Diabetes. Aug, 2014  |   Pubmed ID: 25060885
• IL-6-dependent Proliferation of Alpha Cells in Mice with Partial Pancreatic-duct Ligation
  Diabetologia. Jul, 2014  |   Pubmed ID: 24759958
• Transient Cytokine Treatment Induces Acinar Cell Reprogramming and Regenerates Functional Beta Cell Mass in Diabetic Mice
  Nature Biotechnology. Jan, 2014  |   Pubmed ID: 24240391
• Short-term Overexpression of VEGF-A in Mouse Beta Cells Indirectly Stimulates Their Proliferation and Protects Against Diabetes
  Diabetologia. Jan, 2014  |   Pubmed ID: 24121626
• Mouse Beta Cell Proliferation is Inhibited by Thymidine Analogue Labelling
  Diabetologia. Dec, 2013  |   Pubmed ID: 24026213
• Conditional Hypovascularization and Hypoxia in Islets Do Not Overtly Influence Adult β-cell Mass or Function
  Diabetes. Dec, 2013  |   Pubmed ID: 23974922
• Spatiotemporal Patterns of Multipotentiality in Ptf1a-expressing Cells During Pancreas Organogenesis and Injury-induced Facultative Restoration
  Development (Cambridge, England). Feb, 2013  |   Pubmed ID: 23325761
• Plasticity of Adult Human Pancreatic Duct Cells by Neurogenin3-mediated Reprogramming
  PloS One. 2012  |   Pubmed ID: 22606327
• Interaction of Glibenclamide and Metformin at the Level of Translation in Pancreatic β Cells
  The Journal of Endocrinology. Feb, 2011  |   Pubmed ID: 21084384
• Derepression of Polycomb Targets During Pancreatic Organogenesis Allows Insulin-producing Beta-cells to Adopt a Neural Gene Activity Program
  Genome Research. Jun, 2010  |   Pubmed ID: 20395405
• Ectopic Expression of E2F1 Stimulates Beta-cell Proliferation and Function
  Diabetes. Jun, 2010  |   Pubmed ID: 20299467
• Akt Activation Protects Pancreatic Beta Cells from AMPK-mediated Death Through Stimulation of MTOR
  Biochemical Pharmacology. May, 2008  |   Pubmed ID: 18377870
• Beta Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas
  Cell. Jan, 2008  |   Pubmed ID: 18243096
• Specificity in Beta Cell Expression of L-3-hydroxyacyl-CoA Dehydrogenase, Short Chain, and Potential Role in Down-regulating Insulin Release
  The Journal of Biological Chemistry. Jul, 2007  |   Pubmed ID: 17491019
• Glucagon-like Peptide-1 Stimulates GABA Formation by Pancreatic Beta-cells at the Level of Glutamate Decarboxylase
  American Journal of Physiology. Endocrinology and Metabolism. Apr, 2007  |   Pubmed ID: 17190904
• Glycemic Control of Apoptosis in the Pancreatic Beta Cell: Danger of Extremes?
  Antioxidants & Redox Signaling. Mar, 2007  |   Pubmed ID: 17184175
• Increased Oxygen Radical Formation and Mitochondrial Dysfunction Mediate Beta Cell Apoptosis Under Conditions of AMP-activated Protein Kinase Stimulation
  Free Radical Biology & Medicine. Jan, 2007  |   Pubmed ID: 17157194
• IA1 is NGN3-dependent and Essential for Differentiation of the Endocrine Pancreas
  The EMBO Journal. Mar, 2006  |   Pubmed ID: 16511571
• Glucose Inhibits GABA Release by Pancreatic Beta-cells Through an Increase in GABA Shunt Activity
  American Journal of Physiology. Endocrinology and Metabolism. Mar, 2006  |   Pubmed ID: 16249254
• Metformin Reduces Adiponectin Protein Expression and Release in 3T3-L1 Adipocytes Involving Activation of AMP Activated Protein Kinase
  European Journal of Pharmacology. Aug, 2005  |   Pubmed ID: 16039647
• Adiponectin-mediated Stimulation of AMP-activated Protein Kinase (AMPK) in Pancreatic Beta Cells
  Life Sciences. Jul, 2005  |   Pubmed ID: 15893773
• Glucose Suppresses Superoxide Generation in Metabolically Responsive Pancreatic Beta Cells
  The Journal of Biological Chemistry. May, 2005  |   Pubmed ID: 15774474
• Metformin-induced Stimulation of AMP-activated Protein Kinase in Beta-cells Impairs Their Glucose Responsiveness and Can Lead to Apoptosis
  Biochemical Pharmacology. Aug, 2004  |   Pubmed ID: 15242807
• Dihydropteridine Reductase As an Alternative to Dihydrofolate Reductase for Synthesis of Tetrahydrofolate in Thermus Thermophilus
  Journal of Bacteriology. Jan, 2004  |   Pubmed ID: 14702303
• Prolonged Culture in Low Glucose Induces Apoptosis of Rat Pancreatic Beta-cells Through Induction of C-myc
  Biochemical and Biophysical Research Communications. Dec, 2003  |   Pubmed ID: 14651961
• Variations in IB1/JIP1 Expression Regulate Susceptibility of Beta-cells to Cytokine-induced Apoptosis Irrespective of C-Jun NH2-terminal Kinase Signaling
  Diabetes. Oct, 2003  |   Pubmed ID: 14514632
• Purification of Rat Pancreatic B-cells by Fluorescence-activated Cell Sorting
  Methods in Molecular Medicine. 2003  |   Pubmed ID: 12619712
• Recapitulation of Embryonic Neuroendocrine Differentiation in Adult Human Pancreatic Duct Cells Expressing Neurogenin 3
  The Journal of Cell Biology. Oct, 2002  |   Pubmed ID: 12403815
• Sustained Activation of AMP-activated Protein Kinase Induces C-Jun N-terminal Kinase Activation and Apoptosis in Liver Cells
  FEBS Letters. Aug, 2002  |   Pubmed ID: 12208500
• Specific Expression of Bax-omega in Pancreatic Beta-cells is Down-regulated by Cytokines Before the Onset of Apoptosis
  Endocrinology. Jan, 2002  |   Pubmed ID: 11751624