Martin Picard

Publications

• Cilengitide Treatment of Newly Diagnosed Glioblastoma Patients Does Not Alter Patterns of Progression
  Journal of Neuro-oncology. Jan, 2014  |   Pubmed ID: 24442484
• Mitochondria Impact Brain Function and Cognition
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014  |   Pubmed ID: 24367081
• Role of Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-alpha (PGC-1α) in Denervation-induced Atrophy in Aged Muscle: Facts and Hypotheses
  Longevity & Healthspan. 2013  |   Pubmed ID: 24472348
• Allostatic Load As a Tool for Monitoring Physiological Dysregulations and Comorbidities in Patients with Severe Mental Illnesses
  Harvard Review of Psychiatry. Nov-Dec, 2013  |   Pubmed ID: 24201821
• Acute Exercise Remodels Mitochondrial Membrane Interactions in Mouse Skeletal Muscle
  Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2013  |   Pubmed ID: 23970537
• Hoechst Likes to Play Hide and Seek...use It with Caution!
  Analytical Biochemistry. Sep, 2013  |   Pubmed ID: 23743152
• Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging
  Diabetes. Mar, 2013  |   Pubmed ID: 23431006
• Mitochondrial Morphology Transitions and Functions: Implications for Retrograde Signaling?
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2013  |   Pubmed ID: 23364527
• Mitochondrial Morphology, Topology, and Membrane Interactions in Skeletal Muscle: a Quantitative Three-dimensional Electron Microscopy Study
  Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2013  |   Pubmed ID: 23104694
• Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm During Mechanical Ventilation
  American Journal of Respiratory and Critical Care Medicine. Dec, 2012  |   Pubmed ID: 23024021
• Mitochondrial Function in Permeabilized Cardiomyocytes is Largely Preserved in the Senescent Rat Myocardium
  PloS One. 2012  |   Pubmed ID: 22912774
• Integrins As Therapeutic Targets
  Trends in Pharmacological Sciences. Jul, 2012  |   Pubmed ID: 22633092
• Stoichiometry of the MexA-OprM Binding, As Investigated by Blue Native Gel Electrophoresis
  Electrophoresis. Apr, 2012  |   Pubmed ID: 22589107
• Photo-induced Proton Gradients for the in Vitro Investigation of Bacterial Efflux Pumps
  Scientific Reports. 2012  |   Pubmed ID: 22400101
• Mitochondria: Starving to Reach Quorum?: Insight into the Physiological Purpose of Mitochondrial Fusion
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Apr, 2012  |   Pubmed ID: 22290641
• Activity Monitoring of Functional OprM Using a Biomimetic Microfluidic Device
  The Analyst. Feb, 2012  |   Pubmed ID: 22215439
• Mitochondrial Functional Specialization in Glycolytic and Oxidative Muscle Fibers: Tailoring the Organelle for Optimal Function
  American Journal of Physiology. Cell Physiology. Feb, 2012  |   Pubmed ID: 22031602
• Pathways to Aging: the Mitochondrion at the Intersection of Biological and Psychosocial Sciences
  Journal of Aging Research. 2011  |   Pubmed ID: 21961065
• Alterations in Intrinsic Mitochondrial Function with Aging Are Fiber Type-specific and Do Not Explain Differential Atrophy Between Muscles
  Aging Cell. Dec, 2011  |   Pubmed ID: 21933339
• A Transdisciplinary Perspective of Chronic Stress in Relation to Psychopathology Throughout Life Span Development
  Development and Psychopathology. Aug, 2011  |   Pubmed ID: 21756430
• Mitochondria: Isolation, Structure and Function
  The Journal of Physiology. Sep, 2011  |   Pubmed ID: 21708903
• Mitochondrial Structure and Function Are Disrupted by Standard Isolation Methods
  PloS One. 2011  |   Pubmed ID: 21512578
• The Need for a Trans-disciplinary, Global Health Framework
  Journal of Alternative and Complementary Medicine (New York, N.Y.). Feb, 2011  |   Pubmed ID: 21309708
• Mitochondrial Functional Impairment with Aging is Exaggerated in Isolated Mitochondria Compared to Permeabilized Myofibers
  Aging Cell. Dec, 2010  |   Pubmed ID: 20849523
• Targeting Integrins in Malignant Glioma
  Targeted Oncology. Sep, 2010  |   Pubmed ID: 20820929
• Phase I/IIa Study of Cilengitide and Temozolomide with Concomitant Radiotherapy Followed by Cilengitide and Temozolomide Maintenance Therapy in Patients with Newly Diagnosed Glioblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2010  |   Pubmed ID: 20439646
• Structural and Dynamical Insights into the Opening Mechanism of P. Aeruginosa OprM Channel
  Structure (London, England : 1993). Mar, 2010  |   Pubmed ID: 20399187
• Randomized Phase II Study of Cilengitide, an Integrin-targeting Arginine-glycine-aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2008  |   Pubmed ID: 18981465
• The Mitochondrial Phenotype of Peripheral Muscle in Chronic Obstructive Pulmonary Disease: Disuse or Dysfunction?
  American Journal of Respiratory and Critical Care Medicine. Nov, 2008  |   Pubmed ID: 18755922
• Resistance to Ca2+-induced Opening of the Permeability Transition Pore Differs in Mitochondria from Glycolytic and Oxidative Muscles
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2008  |   Pubmed ID: 18495829
• The Structural Basis of Calcium Transport by the Calcium Pump
  Nature. Dec, 2007  |   Pubmed ID: 18075584
• Inhibitors Bound to Ca(2+)-free Sarcoplasmic Reticulum Ca(2+)-ATPase Lock Its Transmembrane Region but Not Necessarily Its Cytosolic Region, Revealing the Flexibility of the Loops Connecting Transmembrane and Cytosolic Domains
  Biochemistry. Dec, 2007  |   Pubmed ID: 18052080
• Ca2+ Versus Mg2+ Coordination at the Nucleotide-binding Site of the Sarcoplasmic Reticulum Ca2+-ATPase
  Journal of Molecular Biology. Apr, 2007  |   Pubmed ID: 17335848
• Conformational Changes in Sarcoplasmic Reticulum Ca(2+)-ATPase Mutants: Effect of Mutations Either at Ca(2+)-binding Site II or at Tryptophan 552 in the Cytosolic Domain
  Biochemistry. Apr, 2006  |   Pubmed ID: 16618114
• Protective and Inhibitory Effects of Various Types of Amphipols on the Ca2+-ATPase from Sarcoplasmic Reticulum: a Comparative Study
  Biochemistry. Feb, 2006  |   Pubmed ID: 16460032
• Effects of Inhibitors on Luminal Opening of Ca2+ Binding Sites in an E2P-like Complex of Sarcoplasmic Reticulum Ca22+-ATPase with Be22+-fluoride
  The Journal of Biological Chemistry. Feb, 2006  |   Pubmed ID: 16332689
• The Average Conformation at Micromolar [Ca2+] of Ca2+-atpase with Bound Nucleotide Differs from That Adopted with the Transition State Analog ADP.AlFx or with AMPPCP Under Crystallization Conditions at Millimolar [Ca2+]
  The Journal of Biological Chemistry. May, 2005  |   Pubmed ID: 15757892
• Stabilization of Membranes Upon Interaction of Amphipathic Polymers with Membrane Proteins
  Protein Science : a Publication of the Protein Society. Nov, 2004  |   Pubmed ID: 15459343
• Involvement of the L6-7 Loop in SERCA1a Ca2+-ATPase Activation by Ca2+ (or Sr2+) and ATP
  The Journal of Biological Chemistry. Jul, 2004  |   Pubmed ID: 15155750
• Functional Properties of Sarcoplasmic Reticulum Ca(2+)-ATPase After Proteolytic Cleavage at Leu119-Lys120, Close to the A-domain
  The Journal of Biological Chemistry. Mar, 2004  |   Pubmed ID: 14672956