Martin Picard Laboratoire de Cristallographie & RMN Biologiques CNRS & Université Paris Descartes Biography Publications Institution JoVE Articles Martin Picard has not added a biography. If you are Martin Picard and would like to personalize this page please email our Author Liaison for assistance. Publications Cilengitide Treatment of Newly Diagnosed Glioblastoma Patients Does Not Alter Patterns of Progression Journal of Neuro-oncology. Jan, 2014 | Pubmed ID: 24442484 Mitochondria Impact Brain Function and Cognition Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24367081 Role of Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-alpha (PGC-1α) in Denervation-induced Atrophy in Aged Muscle: Facts and Hypotheses Longevity & Healthspan. 2013 | Pubmed ID: 24472348 Allostatic Load As a Tool for Monitoring Physiological Dysregulations and Comorbidities in Patients with Severe Mental Illnesses Harvard Review of Psychiatry. Nov-Dec, 2013 | Pubmed ID: 24201821 Acute Exercise Remodels Mitochondrial Membrane Interactions in Mouse Skeletal Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2013 | Pubmed ID: 23970537 Hoechst Likes to Play Hide and Seek...use It with Caution! Analytical Biochemistry. Sep, 2013 | Pubmed ID: 23743152 Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging Diabetes. Mar, 2013 | Pubmed ID: 23431006 Mitochondrial Morphology Transitions and Functions: Implications for Retrograde Signaling? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2013 | Pubmed ID: 23364527 Mitochondrial Morphology, Topology, and Membrane Interactions in Skeletal Muscle: a Quantitative Three-dimensional Electron Microscopy Study Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2013 | Pubmed ID: 23104694 Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm During Mechanical Ventilation American Journal of Respiratory and Critical Care Medicine. Dec, 2012 | Pubmed ID: 23024021 Mitochondrial Function in Permeabilized Cardiomyocytes is Largely Preserved in the Senescent Rat Myocardium PloS One. 2012 | Pubmed ID: 22912774 Integrins As Therapeutic Targets Trends in Pharmacological Sciences. Jul, 2012 | Pubmed ID: 22633092 Stoichiometry of the MexA-OprM Binding, As Investigated by Blue Native Gel Electrophoresis Electrophoresis. Apr, 2012 | Pubmed ID: 22589107 Photo-induced Proton Gradients for the in Vitro Investigation of Bacterial Efflux Pumps Scientific Reports. 2012 | Pubmed ID: 22400101 Mitochondria: Starving to Reach Quorum?: Insight into the Physiological Purpose of Mitochondrial Fusion BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Apr, 2012 | Pubmed ID: 22290641 Activity Monitoring of Functional OprM Using a Biomimetic Microfluidic Device The Analyst. Feb, 2012 | Pubmed ID: 22215439 Mitochondrial Functional Specialization in Glycolytic and Oxidative Muscle Fibers: Tailoring the Organelle for Optimal Function American Journal of Physiology. Cell Physiology. Feb, 2012 | Pubmed ID: 22031602 Pathways to Aging: the Mitochondrion at the Intersection of Biological and Psychosocial Sciences Journal of Aging Research. 2011 | Pubmed ID: 21961065 Alterations in Intrinsic Mitochondrial Function with Aging Are Fiber Type-specific and Do Not Explain Differential Atrophy Between Muscles Aging Cell. Dec, 2011 | Pubmed ID: 21933339 A Transdisciplinary Perspective of Chronic Stress in Relation to Psychopathology Throughout Life Span Development Development and Psychopathology. Aug, 2011 | Pubmed ID: 21756430 Mitochondria: Isolation, Structure and Function The Journal of Physiology. Sep, 2011 | Pubmed ID: 21708903 Mitochondrial Structure and Function Are Disrupted by Standard Isolation Methods PloS One. 2011 | Pubmed ID: 21512578 The Need for a Trans-disciplinary, Global Health Framework Journal of Alternative and Complementary Medicine (New York, N.Y.). Feb, 2011 | Pubmed ID: 21309708 Mitochondrial Functional Impairment with Aging is Exaggerated in Isolated Mitochondria Compared to Permeabilized Myofibers Aging Cell. Dec, 2010 | Pubmed ID: 20849523 Targeting Integrins in Malignant Glioma Targeted Oncology. Sep, 2010 | Pubmed ID: 20820929 Phase I/IIa Study of Cilengitide and Temozolomide with Concomitant Radiotherapy Followed by Cilengitide and Temozolomide Maintenance Therapy in Patients with Newly Diagnosed Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2010 | Pubmed ID: 20439646 Structural and Dynamical Insights into the Opening Mechanism of P. Aeruginosa OprM Channel Structure (London, England : 1993). Mar, 2010 | Pubmed ID: 20399187 Randomized Phase II Study of Cilengitide, an Integrin-targeting Arginine-glycine-aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2008 | Pubmed ID: 18981465 The Mitochondrial Phenotype of Peripheral Muscle in Chronic Obstructive Pulmonary Disease: Disuse or Dysfunction? American Journal of Respiratory and Critical Care Medicine. Nov, 2008 | Pubmed ID: 18755922 Resistance to Ca2+-induced Opening of the Permeability Transition Pore Differs in Mitochondria from Glycolytic and Oxidative Muscles American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2008 | Pubmed ID: 18495829 The Structural Basis of Calcium Transport by the Calcium Pump Nature. Dec, 2007 | Pubmed ID: 18075584 Inhibitors Bound to Ca(2+)-free Sarcoplasmic Reticulum Ca(2+)-ATPase Lock Its Transmembrane Region but Not Necessarily Its Cytosolic Region, Revealing the Flexibility of the Loops Connecting Transmembrane and Cytosolic Domains Biochemistry. Dec, 2007 | Pubmed ID: 18052080 Ca2+ Versus Mg2+ Coordination at the Nucleotide-binding Site of the Sarcoplasmic Reticulum Ca2+-ATPase Journal of Molecular Biology. Apr, 2007 | Pubmed ID: 17335848 Conformational Changes in Sarcoplasmic Reticulum Ca(2+)-ATPase Mutants: Effect of Mutations Either at Ca(2+)-binding Site II or at Tryptophan 552 in the Cytosolic Domain Biochemistry. Apr, 2006 | Pubmed ID: 16618114 Protective and Inhibitory Effects of Various Types of Amphipols on the Ca2+-ATPase from Sarcoplasmic Reticulum: a Comparative Study Biochemistry. Feb, 2006 | Pubmed ID: 16460032 Effects of Inhibitors on Luminal Opening of Ca2+ Binding Sites in an E2P-like Complex of Sarcoplasmic Reticulum Ca22+-ATPase with Be22+-fluoride The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16332689 The Average Conformation at Micromolar [Ca2+] of Ca2+-atpase with Bound Nucleotide Differs from That Adopted with the Transition State Analog ADP.AlFx or with AMPPCP Under Crystallization Conditions at Millimolar [Ca2+] The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15757892 Stabilization of Membranes Upon Interaction of Amphipathic Polymers with Membrane Proteins Protein Science : a Publication of the Protein Society. Nov, 2004 | Pubmed ID: 15459343 Involvement of the L6-7 Loop in SERCA1a Ca2+-ATPase Activation by Ca2+ (or Sr2+) and ATP The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15155750 Functional Properties of Sarcoplasmic Reticulum Ca(2+)-ATPase After Proteolytic Cleavage at Leu119-Lys120, Close to the A-domain The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14672956 In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa Alice Verchère1, Manuela Dezi1, Isabelle Broutin1, Martin Picard1 1Laboratoire de Cristallographie & RMN Biologiques, CNRS & Université Paris Descartes JoVE 50894 Biology
In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa Alice Verchère1, Manuela Dezi1, Isabelle Broutin1, Martin Picard1 1Laboratoire de Cristallographie & RMN Biologiques, CNRS & Université Paris Descartes JoVE 50894 Biology