Nathan J. Alves Department of Emergency Medicine Indiana University School of Medicine Biography Publications Institution JoVE Articles Nathan J. AlvesAssistant Professor Dr. Alves received his PhD in Chemical and Biomolecular Engineering from the University of Notre Dame. The research he conducts, while spanning many disciplines, is centered on the development of translational technologies, treatments, and techniques that can be utilized to have a positive impact on people’s lives.He has extensive experience in: site-specific antibody modification, oriented antibody immobilization for advanced diagnostics, nanoparticle delivery, and packaging of pharmaceutical agents/enzymes to treat various diseases. Currently, Dr. Alves is an Assistant Professor at the Indiana University School of Medicine in the Department of Emergency Medicine with a joint appointment at Purdue in Biomedical Engineering. His multidisciplinary background affords him a unique perspective to tackle complex medical device and therapeutic development problems. Publications Fibrin Clot Formation Under Diverse Clotting Conditions: Comparing Turbidimetry and Thromboelastography Thrombosis Research. Mar, 2020 | Pubmed ID: 31954276 Inhaled Nitric Oxide to Control Platelet Hyper-reactivity in Patients with Acute Submassive Pulmonary Embolism Nitric Oxide : Biology and Chemistry. 03, 2020 | Pubmed ID: 31940502 HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death American Journal of Respiratory Cell and Molecular Biology. 03, 2019 | Pubmed ID: 30321057 Environmental Decontamination of a Chemical Warfare Simulant Utilizing a Membrane Vesicle-Encapsulated Phosphotriesterase ACS Applied Materials & Interfaces. May, 2018 | Pubmed ID: 29672020 Disinhibiting Neurons in the Dorsomedial Hypothalamus Delays the Onset of Exertional Fatigue and Exhaustion in Rats Exercising in a Warm Environment Brain Research. 06, 2018 | Pubmed ID: 29577887 Affinity Purification of Bacterial Outer Membrane Vesicles (OMVs) Utilizing a His-tag Mutant Research in Microbiology. Oct, 2016 | Pubmed ID: 27773766 Variable Resistance to Plasminogen Activator Initiated Fibrinolysis for Intermediate-Risk Pulmonary Embolism PloS One. Month, 2016 | Pubmed ID: 26866684 Comparison of Isoflurane and α-chloralose in an Anesthetized Swine Model of Acute Pulmonary Embolism Producing Right Ventricular Dysfunction Comparative Medicine. Feb, 2015 | Pubmed ID: 25730758 Comparative Study on the Inhibition of Plasmin and Delta-plasmin Via Benzamidine Derivatives Biochemical and Biophysical Research Communications. Feb, 2015 | Pubmed ID: 25576865 Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization Ziqian Zeng1,2, Tanmaye Nallan Chakravarthula1,2, Nathan J. Alves1,2 1Emergency Medicine Department, Indiana University School of Medicine, 2Weldon School of Biomedical Engineering, Purdue University JoVE 61519 Medicine Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification Nathan J. Alves1,2, Kendrick B. Turner1, Scott A. Walper1 1Center for Bio/Molecular Science & Engineering, Naval Research Laboratory, 2Department of Emergency Medicine, Indiana University of School of Medicine JoVE 54458 Biochemistry
Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization Ziqian Zeng1,2, Tanmaye Nallan Chakravarthula1,2, Nathan J. Alves1,2 1Emergency Medicine Department, Indiana University School of Medicine, 2Weldon School of Biomedical Engineering, Purdue University JoVE 61519 Medicine
Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification Nathan J. Alves1,2, Kendrick B. Turner1, Scott A. Walper1 1Center for Bio/Molecular Science & Engineering, Naval Research Laboratory, 2Department of Emergency Medicine, Indiana University of School of Medicine JoVE 54458 Biochemistry