Peter Agre Biography Publications JoVE Articles Peter Agre has not added a biography. If you are Peter Agre and would like to personalize this page please email our Author Liaison for assistance. Publications Malaria Antifolate Resistance with Contrasting Plasmodium Falciparum Dihydrofolate Reductase (DHFR) Polymorphisms in Humans and Anopheles Mosquitoes Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22065788 Aquaporin Water Channel AgAQP1 in the Malaria Vector Mosquito Anopheles Gambiae During Blood Feeding and Humidity Adaptation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21444767 Effects of Acetaldehyde on Hepatocyte Glycerol Uptake and Cell Size: Implication of Aquaporin 9 Alcoholism, Clinical and Experimental Research. May, 2011 | Pubmed ID: 21294757 Presidential Address. Life on the River of Science Science (New York, N.Y.). Jan, 2011 | Pubmed ID: 21284129 The Family Naturalist Nature. Oct, 2010 | Pubmed ID: 20944611 Advancing Science, Promoting Peace Science Translational Medicine. Aug, 2010 | Pubmed ID: 20739678 Bridging Science and Society Science (New York, N.Y.). Feb, 2010 | Pubmed ID: 20167748 The Scientific Diplomat Nature. Jan, 2010 | Pubmed ID: 20090722 Translate the Promise into the Practical: an Interview with Peter Agre, MD, on Malaria, Translation, and Outreach. Interview by Elaine Musgrave Clinical and Translational Science. Apr, 2009 | Pubmed ID: 20443876 Reduced Arsenic Clearance and Increased Toxicity in Aquaglyceroporin-9-null Mice Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19805235 Aquaporin 6 Binds Calmodulin in a Calcium-dependent Manner Biochemical and Biophysical Research Communications. May, 2009 | Pubmed ID: 19336226 Targeted Disruption of the Cl-/HCO3- Exchanger Ae2 Results in Osteopetrosis in Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19164575 Discovery of the Aquaporins and Development of the Field Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19096770 Osteoclast Differentiation and Function in Aquaglyceroporin AQP9-null Mice Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Mar, 2009 | Pubmed ID: 18666888 Proteomic Analysis of Lithium-induced Nephrogenic Diabetes Insipidus: Mechanisms for Aquaporin 2 Down-regulation and Cellular Proliferation Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18296634 Mercury Chloride Decreases the Water Permeability of Aquaporin-4-reconstituted Proteoliposomes Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Jun, 2008 | Pubmed ID: 18167118 Aquaporin 9 is the Major Pathway for Glycerol Uptake by Mouse Erythrocytes, with Implications for Malarial Virulence Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17636116 Defective Glycerol Metabolism in Aquaporin 9 (AQP9) Knockout Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17360690 Aquaglyceroporin PbAQP During Intraerythrocytic Development of the Malaria Parasite Plasmodium Berghei Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17284593 Functional Analysis of the Aquaporin Gene Family in Caenorhabditis Elegans American Journal of Physiology. Cell Physiology. May, 2007 | Pubmed ID: 17229810 The Israeli-Palestinian Science Organization Science (New York, N.Y.). Jan, 2007 | Pubmed ID: 17204624 Fast and Selective Ammonia Transport by Aquaporin-8 The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17189259 Molecular Cloning and Characterization of Mouse Aquaporin 6 Biochemical and Biophysical Research Communications. Jan, 2007 | Pubmed ID: 17112474 Temporary Loss of Perivascular Aquaporin-4 in Neocortex After Transient Middle Cerebral Artery Occlusion in Mice Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16938871 Aquaporin-11: a Channel Protein Lacking Apparent Transport Function Expressed in Brain BMC Biochemistry. 2006 | Pubmed ID: 16650285 Physician-scientists Are Needed Now More Than Ever Nature. Apr, 2006 | Pubmed ID: 16598232 The Aquaporin Water Channels Proceedings of the American Thoracic Society. 2006 | Pubmed ID: 16493146 Isolation of C. Elegans Deletion Mutants Following ENU Mutagenesis and Thermostable Restriction Enzyme PCR Screening Molecular Biotechnology. Jan, 2006 | Pubmed ID: 16382185 Co-axial Association of Recombinant Eye Lens Aquaporin-0 Observed in Loosely Packed 3D Crystals Journal of Molecular Biology. Jan, 2006 | Pubmed ID: 16309700 Purification and Functional Characterization of Aquaporin-8 Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Mar, 2006 | Pubmed ID: 15948717 Determinants of AQP6 Trafficking to Intracellular Sites Versus the Plasma Membrane in Transfected Mammalian Cells Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Feb, 2006 | Pubmed ID: 15892693 Structural Basis for Conductance by the Archaeal Aquaporin AqpM at 1.68 A Proceedings of the National Academy of Sciences of the United States of America. Dec, 2005 | Pubmed ID: 16361443 Aquaporin Expression and Freeze Tolerance in Candida Albicans Applied and Environmental Microbiology. Oct, 2005 | Pubmed ID: 16204575 Identification of AQP5 in Lipid Rafts and Its Translocation to Apical Membranes by Activation of M3 MAChRs in Interlobular Ducts of Rat Parotid Gland American Journal of Physiology. Cell Physiology. Nov, 2005 | Pubmed ID: 16107506 Using Ethics to Fight Bioterrorism Science (New York, N.Y.). Aug, 2005 | Pubmed ID: 16106523 Membrane Water Transport and Aquaporins: Looking Back Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Jun, 2005 | Pubmed ID: 15901244 Conversion of Aquaporin 6 from an Anion Channel to a Water-selective Channel by a Single Amino Acid Substitution Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15671159 Loss of Perivascular Aquaporin 4 May Underlie Deficient Water and K+ Homeostasis in the Human Epileptogenic Hippocampus Proceedings of the National Academy of Sciences of the United States of America. Jan, 2005 | Pubmed ID: 15657133 Nobel Lecture. Aquaporin Water Channels Bioscience Reports. Jun, 2004 | Pubmed ID: 16209125 Aquaporin Water Channels (Nobel Lecture) Angewandte Chemie (International Ed. in English). Aug, 2004 | Pubmed ID: 15368374 Structural Biology. The Atomic Architecture of a Gas Channel Science (New York, N.Y.). Sep, 2004 | Pubmed ID: 15361612 From Structure to Disease: the Evolving Tale of Aquaporin Biology Nature Reviews. Molecular Cell Biology. Sep, 2004 | Pubmed ID: 15340377 Arsenic Trioxide Uptake by Human and Rat Aquaglyceroporins Biochemical and Biophysical Research Communications. Apr, 2004 | Pubmed ID: 15044109 Immunolocalization of AQP-5 in Rat Parotid and Submandibular Salivary Glands After Stimulation or Inhibition of Secretion in Vivo American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2004 | Pubmed ID: 14988067 Molecular Dissection of Water and Glycerol Permeability of the Aquaglyceroporin from Plasmodium Falciparum by Mutational Analysis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14734807 Alpha-syntrophin Deletion Removes the Perivascular but Not Endothelial Pool of Aquaporin-4 at the Blood-brain Barrier and Delays the Development of Brain Edema in an Experimental Model of Acute Hyponatremia FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2004 | Pubmed ID: 14734638 Aquaporin Water Channels: Molecular Mechanisms for Human Diseases FEBS Letters. Nov, 2003 | Pubmed ID: 14630322 Delayed K+ Clearance Associated with Aquaporin-4 Mislocalization: Phenotypic Defects in Brains of Alpha-syntrophin-null Mice Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14597704 Aquaporin-4 Square Array Assembly: Opposing Actions of M1 and M23 Isoforms Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14597700 Aquaglyceroporin AQP9: Solute Permeation and Metabolic Control of Expression in Liver Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12594337 An Alpha-syntrophin-dependent Pool of AQP4 in Astroglial End-feet Confers Bidirectional Water Flow Between Blood and Brain Proceedings of the National Academy of Sciences of the United States of America. Feb, 2003 | Pubmed ID: 12578959 Functional Expression and Characterization of an Archaeal Aquaporin. AqpM from Methanothermobacter Marburgensis The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12519768 Delayed Onset of Brain Edema and Mislocalization of Aquaporin-4 in Dystrophin-null Transgenic Mice Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12232046 Characterization of Aquaporin-6 As a Nitrate Channel in Mammalian Cells. Requirement of Pore-lining Residue Threonine 63 The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12177001 Structure and Function of Water Channels Current Opinion in Structural Biology. Aug, 2002 | Pubmed ID: 12163075 Aquaporin Water Channels--from Atomic Structure to Clinical Medicine The Journal of Physiology. Jul, 2002 | Pubmed ID: 12096044 Aquaporin Water Channels: Atomic Structure Molecular Dynamics Meet Clinical Medicine The Journal of Clinical Investigation. Jun, 2002 | Pubmed ID: 12045251 Ion Permeation of AQP6 Water Channel Protein. Single Channel Recordings After Hg2+ Activation The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12034750 Arsenite Transport by Mammalian Aquaglyceroporins AQP7 and AQP9 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002 | Pubmed ID: 11972053 Decreased Pulmonary Vascular Permeability in Aquaporin-1-null Humans Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11773634 Functional Requirement of Aquaporin-5 in Plasma Membranes of Sweat Glands Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11773623 Aquaporins in the Kidney: from Molecules to Medicine Physiological Reviews. Jan, 2002 | Pubmed ID: 11773613 The 2009 Lindau Nobel Laureate Meeting: Peter Agre, Chemistry 2003 Peter Agre JoVE 1565 Editorial