R. Mark Henkelman Mouse Imaging Centre Hospital for Sick Children Biography Publications Institution JoVE Articles R. Mark Henkelman has not added a biography. If you are R. Mark Henkelman and would like to personalize this page please email our Author Liaison for assistance. Publications Preparation of Fixed Mouse Brains for MRI NeuroImage. Jan, 2012 | Pubmed ID: 22305951 Robust Method for 3D Arterial Spin Labeling in Mice Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Nov, 2011 | Pubmed ID: 22102489 Priming of Hypoxia-inducible Factor by Neuronal Nitric Oxide Synthase is Essential for Adaptive Responses to Severe Anemia Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21976486 Dosage-dependent Phenotypes in Models of 16p11.2 Lesions Found in Autism Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21969575 Genes into Geometry: Imaging for Mouse Development in 3D Current Opinion in Genetics & Development. Oct, 2011 | Pubmed ID: 21907568 Brain Abnormalities in a Neuroligin3 R451C Knockin Mouse Model Associated with Autism Autism Research : Official Journal of the International Society for Autism Research. Oct, 2011 | Pubmed ID: 21882360 Mice Lacking Caspase-2 Are Protected from Behavioral Changes, but Not Pathology, in the YAC128 Model of Huntington Disease Molecular Neurodegeneration. 2011 | Pubmed ID: 21854568 Iroquois Homeobox Gene 3 Establishes Fast Conduction in the Cardiac His-Purkinje Network Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21825130 Altered Palmitoylation and Neuropathological Deficits in Mice Lacking HIP14 Human Molecular Genetics. Oct, 2011 | Pubmed ID: 21775500 Semi-automatic Segmentation of Multiple Mouse Embryos in MR Images BMC Bioinformatics. 2011 | Pubmed ID: 21679425 Natural History of Disease in the YAC128 Mouse Reveals a Discrete Signature of Pathology in Huntington Disease Neurobiology of Disease. Jul, 2011 | Pubmed ID: 21458571 Multiple Developmental Programs Are Altered by Loss of Zic1 and Zic4 to Cause Dandy-Walker Malformation Cerebellar Pathogenesis Development (Cambridge, England). Mar, 2011 | Pubmed ID: 21307096 Chromatin Remodelling Complex Dosage Modulates Transcription Factor Function in Heart Development Nature Communications. 2011 | Pubmed ID: 21304516 Suppressor of Fused Controls Mid-hindbrain Patterning and Cerebellar Morphogenesis Via GLI3 Repressor The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2011 | Pubmed ID: 21289193 MRI Phenotyping of Genetically Altered Mice Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21279611 Correlation Between Local Hemodynamics and Lesion Distribution in a Novel Aortic Regurgitation Murine Model of Atherosclerosis Annals of Biomedical Engineering. May, 2011 | Pubmed ID: 21279441 Electrical Remodelling Precedes Heart Failure in an Endothelin-1-induced Model of Cardiomyopathy Cardiovascular Research. Feb, 2011 | Pubmed ID: 21062919 Maze Training in Mice Induces MRI-detectable Brain Shape Changes Specific to the Type of Learning NeuroImage. Feb, 2011 | Pubmed ID: 20932918 A Mouse Model of Heritable Cerebrovascular Disease PloS One. 2010 | Pubmed ID: 21217823 Comparative SNR for High-throughput Mouse Embryo MR Microscopy Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jun, 2010 | Pubmed ID: 20512875 A Mouse Model of Down Syndrome Trisomic for All Human Chromosome 21 Syntenic Regions Human Molecular Genetics. Jul, 2010 | Pubmed ID: 20442137 Systems Biology Through Mouse Imaging Centers: Experience and New Directions Annual Review of Biomedical Engineering. Aug, 2010 | Pubmed ID: 20415591 Hedgehog Regulates Distinct Vascular Patterning Events Through VEGF-dependent and -independent Mechanisms Blood. Jul, 2010 | Pubmed ID: 20339091 Anatomical Phenotyping in a Mouse Model of Fragile X Syndrome with Magnetic Resonance Imaging NeuroImage. Nov, 2010 | Pubmed ID: 20304074 Aortic Regurgitation Dramatically Alters the Distribution of Atherosclerotic Lesions and Enhances Atherogenesis in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2010 | Pubmed ID: 20299687 Genetic Deletion or Pharmacological Inhibition of Dipeptidyl Peptidase-4 Improves Cardiovascular Outcomes After Myocardial Infarction in Mice Diabetes. Apr, 2010 | Pubmed ID: 20097729 Cerebral Asymmetries in 12-week-old C57Bl/6J Mice Measured by Magnetic Resonance Imaging NeuroImage. Apr, 2010 | Pubmed ID: 20026229 Lunatic Fringe-mediated Notch Signaling is Required for Lung Alveogenesis American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2010 | Pubmed ID: 19897741 Reptilian Heart Development and the Molecular Basis of Cardiac Chamber Evolution Nature. Sep, 2009 | Pubmed ID: 19727199 Measurement of Cerebral Blood Volume in Mouse Brain Regions Using Micro-computed Tomography NeuroImage. Oct, 2009 | Pubmed ID: 19362597 Regionally Reduced Brain Volume, Altered Serotonin Neurochemistry, and Abnormal Behavior in Mice Null for the Circadian Rhythm Output Gene Magel2 American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. Dec, 2009 | Pubmed ID: 19199291 GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice Diabetes. Apr, 2009 | Pubmed ID: 19151200 Trading off SNR and Resolution in MR Images NMR in Biomedicine. Jun, 2009 | Pubmed ID: 19123210 Acoustic and Kinetic Behaviour of Definity in Mice Exposed to High Frequency Ultrasound Ultrasound in Medicine & Biology. Feb, 2009 | Pubmed ID: 18950930 P73 Regulates Neurodegeneration and Phospho-tau Accumulation During Aging and Alzheimer's Disease Neuron. Sep, 2008 | Pubmed ID: 18786355 Three-dimensional Analysis of Vascular Development in the Mouse Embryo PloS One. 2008 | Pubmed ID: 18682734 Longitudinal Neuroanatomical Changes Determined by Deformation-based Morphometry in a Mouse Model of Alzheimer's Disease NeuroImage. Aug, 2008 | Pubmed ID: 18547819 Cortical Thickness Measured from MRI in the YAC128 Mouse Model of Huntington's Disease NeuroImage. Jun, 2008 | Pubmed ID: 18387826 Tbx5-dependent Pathway Regulating Diastolic Function in Congenital Heart Disease Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008 | Pubmed ID: 18378906 Optimization of the SNR-resolution Tradeoff for Registration of Magnetic Resonance Images Human Brain Mapping. Oct, 2008 | Pubmed ID: 17957707 Automated Deformation Analysis in the YAC128 Huntington Disease Mouse Model NeuroImage. Jan, 2008 | Pubmed ID: 17942324 Combined Magnetic Resonance and Bioluminescence Imaging of Live Mice Journal of Biomedical Optics. May-Jun, 2007 | Pubmed ID: 17614726 Noninvasive Ultrasonic Measurement of Regional and Local Pulse-wave Velocity in Mice Ultrasound in Medicine & Biology. Sep, 2007 | Pubmed ID: 17561330 Behavioral Phenotypes of Disc1 Missense Mutations in Mice Neuron. May, 2007 | Pubmed ID: 17481393 Resolution Improvement in Emission Optical Projection Tomography Physics in Medicine and Biology. May, 2007 | Pubmed ID: 17473351 MR Technology for Biological Studies in Mice NMR in Biomedicine. May, 2007 | Pubmed ID: 17451169 4D Cardiac MRI in the Mouse NMR in Biomedicine. May, 2007 | Pubmed ID: 17451168 Mouse Behavioral Mutants Have Neuroimaging Abnormalities Human Brain Mapping. Jun, 2007 | Pubmed ID: 17437292 Morphological and Functional Evaluation of Murine Heterotopic Cardiac Grafts Using Ultrasound Biomicroscopy Ultrasound in Medicine & Biology. Jun, 2007 | Pubmed ID: 17434663 Sexual Dimorphism Revealed in the Structure of the Mouse Brain Using Three-dimensional Magnetic Resonance Imaging NeuroImage. May, 2007 | Pubmed ID: 17408971 Magnetic Resonance Imaging with Ultrashort TE (UTE) PULSE Sequences: Technical Considerations Journal of Magnetic Resonance Imaging : JMRI. Feb, 2007 | Pubmed ID: 17260388 Hemodynamics in the Mouse Aortic Arch As Assessed by MRI, Ultrasound, and Numerical Modeling American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2007 | Pubmed ID: 17012350 Presentation of 3D Isotropic Imaging Data for Optimal Viewing Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Dec, 2006 | Pubmed ID: 17075854 High-grade Glioma Formation Results from Postnatal Pten Loss or Mutant Epidermal Growth Factor Receptor Expression in a Transgenic Mouse Glioma Model Cancer Research. Aug, 2006 | Pubmed ID: 16885338 Tbx5-dependent Rheostatic Control of Cardiac Gene Expression and Morphogenesis Developmental Biology. Sep, 2006 | Pubmed ID: 16870172 Using Metamaterial Yokes in NMR Measurements Journal of Magnetic Resonance (San Diego, Calif. : 1997). Oct, 2006 | Pubmed ID: 16859941 In Vivo Magnetic Resonance Imaging and Semiautomated Image Analysis Extend the Brain Phenotype for Cdf/cdf Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2006 | Pubmed ID: 16641223 Retrospective Gating for Mouse Cardiac MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Mar, 2006 | Pubmed ID: 16450339 Anatomical Phenotyping in the Brain and Skull of a Mutant Mouse by Magnetic Resonance Imaging and Computed Tomography Physiological Genomics. Jan, 2006 | Pubmed ID: 16410543 Neuroanatomical Differences Between Mouse Strains As Shown by High-resolution 3D MRI NeuroImage. Jan, 2006 | Pubmed ID: 16084741 Disease Phenotyping: Structural and Functional Readouts Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progrès Des Recherches Pharmaceutiques. 2005 | Pubmed ID: 16329257 Magnetic Resonance Imaging for Detection and Analysis of Mouse Phenotypes NMR in Biomedicine. Nov, 2005 | Pubmed ID: 16206127 Gradient Hysteresis in MRI and NMR Experiments Journal of Magnetic Resonance (San Diego, Calif. : 1997). Dec, 2005 | Pubmed ID: 16188476 Correction of Artefacts in Optical Projection Tomography Physics in Medicine and Biology. Oct, 2005 | Pubmed ID: 16177495 A Gja1 Missense Mutation in a Mouse Model of Oculodentodigital Dysplasia Development (Cambridge, England). Oct, 2005 | Pubmed ID: 16155213 T1, T2 Relaxation and Magnetization Transfer in Tissue at 3T Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Sep, 2005 | Pubmed ID: 16086319 Abnormal Cardiac Inflow Patterns During Postnatal Development in a Mouse Model of Holt-Oram Syndrome American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2005 | Pubmed ID: 15849237 Imaging Articular Cartilage Under Compression--cartilage Elastography Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2005 | Pubmed ID: 15844160 Tbx20 Dose-dependently Regulates Transcription Factor Networks Required for Mouse Heart and Motoneuron Development Development (Cambridge, England). May, 2005 | Pubmed ID: 15843409 Identification of Human Brain Tumour Initiating Cells Nature. Nov, 2004 | Pubmed ID: 15549107 Baf60c is Essential for Function of BAF Chromatin Remodelling Complexes in Heart Development Nature. Nov, 2004 | Pubmed ID: 15525990 Multiple Mouse Biological Loading and Monitoring System for MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Oct, 2004 | Pubmed ID: 15389955 Foxh1 is Essential for Development of the Anterior Heart Field Developmental Cell. Sep, 2004 | Pubmed ID: 15363409 Angiopoietin-1 Causes Reversible Degradation of the Portal Microcirculation in Mice: Implications for Treatment of Liver Disease The American Journal of Pathology. Sep, 2004 | Pubmed ID: 15331413 Comprehensive Transthoracic Cardiac Imaging in Mice Using Ultrasound Biomicroscopy with Anatomical Confirmation by Magnetic Resonance Imaging Physiological Genomics. Jul, 2004 | Pubmed ID: 15114000 MicroCT Scanner Performance and Considerations for Vascular Specimen Imaging Medical Physics. Feb, 2004 | Pubmed ID: 15000616 Ultrasound-guided Left-ventricular Catheterization: a Novel Method of Whole Mouse Perfusion for Microimaging Laboratory Investigation; a Journal of Technical Methods and Pathology. Mar, 2004 | Pubmed ID: 14704721 High-resolution Longitudinal Screening with Magnetic Resonance Imaging in a Murine Brain Cancer Model Neoplasia (New York, N.Y.). Nov-Dec, 2003 | Pubmed ID: 14965447 Multiple-mouse MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jan, 2003 | Pubmed ID: 12509832 Orientational Diffusion Reflects Fiber Structure Within a Voxel Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Sep, 2002 | Pubmed ID: 12210909 Pulse-wave Velocity Measured in One Heartbeat Using MR Tagging Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2002 | Pubmed ID: 12111938 Why Does MTR Change with Neuronal Depolarization? Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Mar, 2002 | Pubmed ID: 11870833 متعددة الماوس تشريحي عصبي التصوير بالرنين المغناطيسي Jun Dazai*1, Shoshana Spring*1, Lindsay S. Cahill1, R. Mark Henkelman1,2 1Mouse Imaging Centre, Hospital for Sick Children, 2Department of Medical Biophysics and Medical Imaging, University of Toronto JoVE 2497 Neuroscience
متعددة الماوس تشريحي عصبي التصوير بالرنين المغناطيسي Jun Dazai*1, Shoshana Spring*1, Lindsay S. Cahill1, R. Mark Henkelman1,2 1Mouse Imaging Centre, Hospital for Sick Children, 2Department of Medical Biophysics and Medical Imaging, University of Toronto JoVE 2497 Neuroscience