Reinhard Gruber Department of Oral Surgery and Stomatology School of Dental Medicine, University of Bern Biography Publications Institution JoVE Articles Reinhard Gruber has not added a biography. If you are Reinhard Gruber and would like to personalize this page please email our Author Liaison for assistance. Publications The Effect of Parathyroid Hormone on Osseointegration in Insulin-Treated Diabetic Rats Implant Dentistry. Jun, 2015 | Pubmed ID: 26126148 Salivary Pellicle Vs Whole Saliva: The Response of Oral Fibroblasts Based on a Genome-Wide Microarray The International Journal of Oral & Maxillofacial Implants. May-Jun, 2015 | Pubmed ID: 26009907 Immediate Implant Placement with Simultaneous Guided Bone Regeneration in the Esthetic Zone: 10-year Clinical and Radiographic Outcomes Clinical Oral Implants Research. Apr, 2015 | Pubmed ID: 25906924 Conditioned Medium of Demineralized Freeze-dried Bone Activates Gene Expression in Periodontal Fibroblasts in Vitro Journal of Periodontology. Jun, 2015 | Pubmed ID: 25786563 The in Vitro Impact of Toothpaste Extracts on Cell Viability European Journal of Oral Sciences. Jun, 2015 | Pubmed ID: 25782087 Conditioned Medium from Fresh and Demineralized Bone Enhances Osteoclastogenesis in Murine Bone Marrow Cultures Clinical Oral Implants Research. Mar, 2015 | Pubmed ID: 25754222 Alveolar Bone Regeneration in Response to Local Application of Calcitriol in Vitamin D Deficient Rats Journal of Clinical Periodontology. Jan, 2015 | Pubmed ID: 25469560 Molecular and Cellular Basis of Bone Resorption Wiener Medizinische Wochenschrift (1946). Feb, 2015 | Pubmed ID: 25223736 Dimethyloxalylglycine Lyophilized Onto Bone Substitutes Increase Vessel Area in Rat Calvarial Defects Clinical Oral Implants Research. May, 2015 | Pubmed ID: 25196581 Sterile-filtered Saliva is a Strong Inducer of IL-6 and IL-8 in Oral Fibroblasts Clinical Oral Investigations. Mar, 2015 | Pubmed ID: 25115993 Osteoclast-like Cells on Deproteinized Bovine Bone Mineral and Biphasic Calcium Phosphate: Light and Transmission Electron Microscopical Observations Clinical Oral Implants Research. Aug, 2015 | Pubmed ID: 24665833 Impact of Bone Graft Harvesting Techniques on Bone Formation and Graft Resorption: a Histomorphometric Study in the Mandibles of Minipigs Clinical Oral Implants Research. Apr, 2015 | Pubmed ID: 24547966 In Vitro Adhesion of Fibroblastic Cells to Titanium Alloy Discs Treated with Sodium Hydroxide Clinical Oral Implants Research. Jan, 2015 | Pubmed ID: 24372935 Bone Substitute Materials Supplemented with Prolyl Hydroxylase Inhibitors Decrease Osteoclastogenesis in Vitro Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Oct, 2014 | Pubmed ID: 25312707 Long-term Storage Affects Adhesion Between Titanium and Zirconia Using Resin Cements The Journal of Adhesive Dentistry. Oct, 2014 | Pubmed ID: 25264548 Proteomic Analysis of Porcine Bone-conditioned Medium The International Journal of Oral & Maxillofacial Implants. Sep-Oct, 2014 | Pubmed ID: 25216150 Emdogain-regulated Gene Expression in Palatal Fibroblasts Requires TGF-βRI Kinase Signaling PloS One. 2014 | Pubmed ID: 25197981 Long-term Stability of Contour Augmentation in the Esthetic Zone: Histologic and Histomorphometric Evaluation of 12 Human Biopsies 14 to 80 Months After Augmentation Journal of Periodontology. Nov, 2014 | Pubmed ID: 25008214 In Vitro Release of Dimethyloxaloylglycine and L-mimosine from Bovine Bone Mineral Archives of Oral Biology. Oct, 2014 | Pubmed ID: 24960117 Human Bone Chips Release of Sclerostin and FGF-23 into the Culture Medium: an in Vitro Pilot Study Clinical Oral Implants Research. Jun, 2014 | Pubmed ID: 24888411 Migration Background is Associated with Caries in Viennese School Children, Even if Parents Have Received a Higher Education BMC Oral Health. 2014 | Pubmed ID: 24886105 Removal of Fractured Endodontic Instruments Using an Nd:YAG Laser Quintessence International (Berlin, Germany : 1985). Jul-Aug, 2014 | Pubmed ID: 24847495 Clinical Study on Survival Rate of Short Implants Placed in the Posterior Mandibular Region: Resonance Frequency Analysis Clinical Oral Implants Research. Apr, 2014 | Pubmed ID: 24735480 Dental and Periodontal Phenotype in Sclerostin Knockout Mice International Journal of Oral Science. Jun, 2014 | Pubmed ID: 24699186 Soft Tissue Wound Healing Around Teeth and Dental Implants Journal of Clinical Periodontology. Apr, 2014 | Pubmed ID: 24641001 Bone-Conditioned Medium Inhibits Osteogenic and Adipogenic Differentiation of Mesenchymal Cells In Vitro Clinical Implant Dentistry and Related Research. Jan, 2014 | Pubmed ID: 24461197 TGF-βRI Kinase Activity Mediates Emdogain-stimulated in Vitro Osteoclastogenesis Clinical Oral Investigations. Jul, 2014 | Pubmed ID: 24221580 Early Bone Apposition to Hydrophilic and Hydrophobic Titanium Implant Surfaces: a Histologic and Histomorphometric Study in Minipigs Clinical Oral Implants Research. Dec, 2014 | Pubmed ID: 24118429 L-mimosine and Dimethyloxaloylglycine Decrease Plasminogen Activation in Periodontal Fibroblasts Journal of Periodontology. Apr, 2014 | Pubmed ID: 23826644 In Vitro Characterization of a Synthetic Calcium Phosphate Bone Graft on Periodontal Ligament Cell and Osteoblast Behavior and Its Combination with an Enamel Matrix Derivative Clinical Oral Investigations. 2014 | Pubmed ID: 23620149 Acid and Alkaline Etching of Sandblasted Zirconia Implants: a Histomorphometric Study in Miniature Pigs Clinical Implant Dentistry and Related Research. Jun, 2014 | Pubmed ID: 23574426 Enamel Matrix Derivative Inhibits Adipocyte Differentiation of 3T3-L1 Cells Via Activation of TGF-βRI Kinase Activity PloS One. 2013 | Pubmed ID: 23951076 Platelets Increase While Serum Reduces the Differentiation and Activity of Osteoclasts in Vitro Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2013 | Pubmed ID: 23703957 Immediate Shear Bond Strengths of a Composite, a Compomer and a Glass Ionomer to a Ceramic Substrate The Journal of Adhesive Dentistry. Aug, 2013 | Pubmed ID: 23534021 In Vitro Evaluation of Demineralized Freeze-dried Bone Allograft in Combination with Enamel Matrix Derivative Journal of Periodontology. Nov, 2013 | Pubmed ID: 23347347 Osteocyte Lacunar Density and Area in Newly Formed Bone of the Augmented Sinus Clinical Oral Implants Research. Mar, 2013 | Pubmed ID: 22784394 Bone Healing Around Titanium Implants in Two Rat Colitis Models Clinical Oral Implants Research. Feb, 2013 | Pubmed ID: 22509782 Impact of Bone Harvesting Techniques on Cell Viability and the Release of Growth Factors of Autografts Clinical Implant Dentistry and Related Research. Aug, 2013 | Pubmed ID: 22375920 Acid and Alkali Etching of Grit Blasted Zirconia: Impact on Adhesion and Osteogenic Differentiation of MG63 Cells in Vitro Dental Materials Journal. 2012 | Pubmed ID: 23207221 Prolyl Hydroxylase Inhibitors Increase the Production of Vascular Endothelial Growth Factor in Dental Pulp-derived Cells Journal of Endodontics. Nov, 2012 | Pubmed ID: 23063224 Reader's Digest of the Pathophysiology of Bone Metastases Wiener Medizinische Wochenschrift (1946). Sep, 2012 | Pubmed ID: 22797871 Resonance Frequency Analysis: a New Diagnostic Tool for Dental Ankylosis European Journal of Oral Sciences. Jun, 2012 | Pubmed ID: 22607343 Impact of Dietary Vitamin D on Osseointegration in the Ovariectomized Rat Clinical Oral Implants Research. Nov, 2012 | Pubmed ID: 22151621 The Impact of Er,Cr:YSGG Laser on the Shear Strength of the Bond Between Dentin and Ceramic is Dependent on the Adhesive Material Lasers in Medical Science. Jul, 2012 | Pubmed ID: 21773765 Resorption of Deproteinized Bovine Bone Mineral in a Porcine Calvaria Augmentation Model Clinical Oral Implants Research. Jan, 2012 | Pubmed ID: 21554404 Peri-implantitis and Late Implant Failures in Postmenopausal Women: a Cross-sectional Study Journal of Clinical Periodontology. Oct, 2011 | Pubmed ID: 21777269 The Effect of BMP-2 on the Osteoconductive Properties of β-tricalcium Phosphate in Rat Calvaria Defects Biomaterials. May, 2011 | Pubmed ID: 21376389 Intermittent Parathyroid Hormone Fails to Stimulate Osseointegration in Diabetic Rats Clinical Oral Implants Research. May, 2011 | Pubmed ID: 21251075 The Impact of Ovariectomy and Hyperglycemia on Graft Consolidation in Rat Calvaria Clinical Oral Implants Research. May, 2011 | Pubmed ID: 21244496 Cortical Porosity of the Mandible in an Osteoporotic Sheep Model Clinical Oral Implants Research. May, 2011 | Pubmed ID: 21087316 Mechanisms Involved in the Inhibition of Osteoclast Generation by the Benzothiophene SERM LY117018 Wiener Klinische Wochenschrift. Nov, 2010 | Pubmed ID: 20938747 Cell Biology of Osteoimmunology Wiener Medizinische Wochenschrift (1946). Sep, 2010 | Pubmed ID: 20714814 Effects of Carboxymethylcellulose and Hydroxypropylmethylcellulose on the Differentiation and Activity of Osteoclasts and Osteoblasts Journal of Biomedical Materials Research. Part A. Nov, 2010 | Pubmed ID: 20665677 Review of Dental Implant Rat Research Models Simulating Osteoporosis or Diabetes The International Journal of Oral & Maxillofacial Implants. May-Jun, 2010 | Pubmed ID: 20556250 Collagen Barrier Membranes Decrease Osteoclastogenesis in Murine Bone Marrow Cultures Clinical Oral Implants Research. Jun, 2010 | Pubmed ID: 20337667 Neutrophil Elastase Activity and Concentrations of Interleukin 1-beta in Crevicular Fluid After Immediate Replacement and Immediate Loading of Implants The British Journal of Oral & Maxillofacial Surgery. Apr, 2010 | Pubmed ID: 19913336 Paste-like Inorganic Bone Matrix: Preclinical Testing of a Prototype Preparation in the Porcine Calvaria Clinical Oral Implants Research. Oct, 2009 | Pubmed ID: 19681965 Development of an in Vitro Model on Cellular Adhesion on Granular Natural Bone Mineral Under Dynamic Seeding Conditions--a Pilot Study Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Nov, 2009 | Pubmed ID: 19582840 Sinus Augmentation Analysis Revised: the Gradient of Graft Consolidation Clinical Oral Implants Research. Oct, 2009 | Pubmed ID: 19519790 Age-related Efficacy of Parathyroid Hormone on Osseointegration in the Rat Clinical Oral Implants Research. Apr, 2009 | Pubmed ID: 19298294 Long-term Effects of Magnetron-sputtered Calcium Phosphate Coating on Osseointegration of Dental Implants in Non-human Primates Clinical Oral Implants Research. Feb, 2009 | Pubmed ID: 19191794 Are Culture-expanded Autogenous Bone Cells a Clinically Reliable Option for Sinus Grafting? Clinical Oral Implants Research. Feb, 2009 | Pubmed ID: 19077153 Activated Platelets Increase Fibrinolysis of Mesenchymal Progenitor Cells Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2009 | Pubmed ID: 19030175 [Bisphosphonate-associated Osteonecrosis of the Jaw] Wiener Klinische Wochenschrift. 2008 | Pubmed ID: 18820850 Bone Cell Responsiveness to Growth and Differentiation Factors Under Hypoxia in Vitro The International Journal of Oral & Maxillofacial Implants. May-Jun, 2008 | Pubmed ID: 18700363 Osseointegration of a Subperiosteal Anchoring Device in the Minipig Mandible American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics. May, 2008 | Pubmed ID: 18456149 Simultaneous in Vivo Comparison of Bone Substitutes in a Guided Bone Regeneration Model Biomaterials. Aug, 2008 | Pubmed ID: 18455786 Activated Platelets Positively Regulate RANKL-mediated Osteoclast Differentiation Journal of Cellular Biochemistry. Dec, 2007 | Pubmed ID: 17957725 The Anti-angiogenic Substance TNP-470 Impairs Peri-implant Bone Formation: a Pilot Study in the Rabbit Metaphysis Model Clinical Oral Implants Research. Jun, 2007 | Pubmed ID: 17298491 Plasminogen Activation by Fibroblasts from Periodontal Ligament and Gingiva is Not Directly Affected by Chemokines in Vitro Archives of Oral Biology. Jul, 2007 | Pubmed ID: 17296163 Fracture Healing in the Elderly Patient Experimental Gerontology. Nov, 2006 | Pubmed ID: 17092679 Radiological and Clinical Follow-up of Machined- and Anodized-surface Implants After Mean Functional Loading for 33 Months Clinical Oral Implants Research. Dec, 2006 | Pubmed ID: 17092223 Activated Platelets Retain Their Potential to Induce Osteoclast-like Cell Formation in Murine Bone Marrow Cultures Platelets. Nov, 2006 | Pubmed ID: 17074724 Age-related Changes of Cell Outgrowth from Rat Calvarial and Mandibular Bone in Vitro Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery. Oct, 2006 | Pubmed ID: 17055735 Soluble RANKL in Crevicular Fluid of Dental Implants: a Pilot Study Clinical Implant Dentistry and Related Research. 2006 | Pubmed ID: 16919021 Osteogenic Differentiation Induced by Bone Morphogenetic Proteins Can Be Suppressed by Platelet-released Supernatant in Vitro Clinical Oral Implants Research. Apr, 2006 | Pubmed ID: 16584415 Bone Marrow Stromal Cells of Young and Adult Rats Respond Similarly to Platelet-released Supernatant and Bone Morphogenetic Protein-6 in Vitro Journal of Periodontology. Apr, 2006 | Pubmed ID: 16584353 Cathepsin K Levels in the Crevicular Fluid of Dental Implants: a Pilot Study Journal of Clinical Periodontology. Apr, 2006 | Pubmed ID: 16553640 Bone Marrow Stromal Cells Can Provide a Local Environment That Favors Migration and Formation of Tubular Structures of Endothelial Cells Tissue Engineering. May-Jun, 2005 | Pubmed ID: 15998229 Platelets Can Neutralize Hydrogen Peroxide in an Acute Toxicity Model with Cells Involved in Granulation Tissue Formation Bone. Apr, 2005 | Pubmed ID: 15784190 Proliferation and Osteogenic Differentiation of Cells from Cortical Bone Cylinders, Bone Particles from Mill, and Drilling Dust Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Feb, 2005 | Pubmed ID: 15690294 Bone Formation Following Sinus Grafting with Autogenous Bone-derived Cells and Bovine Bone Mineral in Minipigs: Preliminary Findings Clinical Oral Implants Research. Dec, 2004 | Pubmed ID: 15533135 Platelet-released Supernatant Increases Matrix Metalloproteinase-2 Production, Migration, Proliferation, and Tube Formation of Human Umbilical Vascular Endothelial Cells Journal of Periodontology. Sep, 2004 | Pubmed ID: 15515342 Porcine Sinus Mucosa Holds Cells That Respond to Bone Morphogenetic Protein (BMP)-6 and BMP-7 with Increased Osteogenic Differentiation in Vitro Clinical Oral Implants Research. Oct, 2004 | Pubmed ID: 15355400 Effect of Platelet-released Growth Factors and Collagen Type I on Osseous Regeneration of Mandibular Defects. A Pilot Study in Minipigs Journal of Clinical Periodontology. Sep, 2004 | Pubmed ID: 15312102 Effects of Fibrin Sealant Protein Concentrate with and Without Platelet-released Growth Factors on Bony Healing of Cortical Mandibular Defects. An Experimental Study in Minipigs Clinical Oral Implants Research. Jun, 2004 | Pubmed ID: 15142092 Platelet-released Supernatants Increase Migration and Proliferation, and Decrease Osteogenic Differentiation of Bone Marrow-derived Mesenchymal Progenitor Cells Under in Vitro Conditions Platelets. Feb, 2004 | Pubmed ID: 14985174 Enhanced Bone-to-implant Contact by Platelet-released Growth Factors in Mandibular Cortical Bone: a Histomorphometric Study in Minipigs The International Journal of Oral & Maxillofacial Implants. Sep-Oct, 2003 | Pubmed ID: 14579956 BMP-6-induced Osteogenic Differentiation of Mesenchymal Cell Lines is Not Modulated by Sex Steroids and Resveratrol Cytokine. Aug 21-Sep 7, 2003 | Pubmed ID: 12967649 Platelets Are Mitogenic for Periosteum-derived Cells Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Sep, 2003 | Pubmed ID: 12919885 Sinus Grafting with Autogenous Platelet-rich Plasma and Bovine Hydroxyapatite. A Histomorphometric Study in Minipigs Clinical Oral Implants Research. Aug, 2003 | Pubmed ID: 12869013 The Stable Analog Carbocyclic TXA2 but Not Platelet-released TXA2 Induces Osteoclast-like Cell Formation Prostaglandins, Leukotrienes, and Essential Fatty Acids. Apr, 2003 | Pubmed ID: 12628222 Platelets Stimulate Proliferation of Bone Cells: Involvement of Platelet-derived Growth Factor, Microparticles and Membranes Clinical Oral Implants Research. Oct, 2002 | Pubmed ID: 12453131 Platelet-released Supernatants Stimulate Formation of Osteoclast-like Cells Through a Prostaglandin/RANKL-dependent Mechanism Bone. May, 2002 | Pubmed ID: 11996911 Bone Conditioned Medium: Preparation and Bioassay Jordi Caballé-Serrano1,2,3, Kosaku Sawada2,5, Guenther Schuldt Filho1,2,6, Dieter D. Bosshardt1,4, Daniel Buser1, Reinhard Gruber1,2 1Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, 2Laboratory of Oral Cell Biology, School of Dental Medicine, University of Bern, 3Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Universitat Internacional de Catalunya, 4Robert K. Schenk Laboratory of Oral Histology, School of Dental Medicine, University of Bern, 5Department of Cranio Maxillofacial Surgery, Inselspital, University of Bern, 6Department of Implant Dentistry, School of Dentistry, Universidade Federal de Santa Catarina JoVE 52707 Biology
Bone Conditioned Medium: Preparation and Bioassay Jordi Caballé-Serrano1,2,3, Kosaku Sawada2,5, Guenther Schuldt Filho1,2,6, Dieter D. Bosshardt1,4, Daniel Buser1, Reinhard Gruber1,2 1Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, 2Laboratory of Oral Cell Biology, School of Dental Medicine, University of Bern, 3Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Universitat Internacional de Catalunya, 4Robert K. Schenk Laboratory of Oral Histology, School of Dental Medicine, University of Bern, 5Department of Cranio Maxillofacial Surgery, Inselspital, University of Bern, 6Department of Implant Dentistry, School of Dentistry, Universidade Federal de Santa Catarina JoVE 52707 Biology
