Rolf Bodmer Development, Aging and Regeneration Program Sanford Burnham Prebys Medical Discovery Institute Biography Publications Institution JoVE Articles Rolf Bodmer has not added a biography. If you are Rolf Bodmer and would like to personalize this page please email our Author Liaison for assistance. Publications Transcriptomic Analysis Identifies a Role of PI3K-Akt Signalling in the Responses of Skeletal Muscle to Acute Hypoxia in Vivo The Journal of Physiology. Sep, 2017 | Pubmed ID: 28688178 SLP-2 Interacts with Parkin in Mitochondria and Prevents Mitochondrial Dysfunction in Parkin-deficient Human IPSC-derived Neurons and Drosophila Human Molecular Genetics. Jul, 2017 | Pubmed ID: 28379402 Experimental Evolution and Heart Function in Drosophila Physiological and Biochemical Zoology : PBZ. Mar/Apr, 2017 | Pubmed ID: 28277957 Modest Overexpression of FOXO Maintains Cardiac Proteostasis and Ameliorates Age-associated Functional Decline Aging Cell. Feb, 2017 | Pubmed ID: 28090761 Expression Patterns of Cardiac Aging in Drosophila Aging Cell. Feb, 2017 | Pubmed ID: 28090760 Extracellular Matrix Downregulation in the Drosophila Heart Preserves Contractile Function and Improves Lifespan Matrix Biology : Journal of the International Society for Matrix Biology. Oct, 2017 | Pubmed ID: 27793636 52 Genetic Loci Influencing Myocardial Mass Journal of the American College of Cardiology. Sep, 2016 | Pubmed ID: 27659466 A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila Journal of Molecular Biology. Jun, 2016 | Pubmed ID: 27107639 The Canonical Wingless Signaling Pathway is Required but Not Sufficient for Inflow Tract Formation in the Drosophila Melanogaster Heart Developmental Biology. May, 2016 | Pubmed ID: 26983369 High Throughput Physiological Screening of IPSC-derived Cardiomyocytes for Drug Development Biochimica Et Biophysica Acta. Jul, 2016 | Pubmed ID: 26952934 SPARC-Dependent Cardiomyopathy in Drosophila Circulation. Cardiovascular Genetics. Apr, 2016 | Pubmed ID: 26839388 Genetic Manipulation of Cardiac Ageing The Journal of Physiology. Apr, 2016 | Pubmed ID: 26060055 Gaining Insights into Diabetic Cardiomyopathy from Drosophila Trends in Endocrinology and Metabolism: TEM. Nov, 2015 | Pubmed ID: 26482877 Cardiac Responses to Hypoxia and Reoxygenation in Drosophila American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2015 | Pubmed ID: 26377557 Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes PloS One. 2015 | Pubmed ID: 26301956 Cellular Mechanisms of Drosophila Heart Morphogenesis Journal of Cardiovascular Development and Disease. Mar, 2015 | Pubmed ID: 26236710 Obesity-associated Cardiac Dysfunction in Starvation-selected Drosophila Melanogaster American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2015 | Pubmed ID: 26136533 Vinculin Network-mediated Cytoskeletal Remodeling Regulates Contractile Function in the Aging Heart Science Translational Medicine. Jun, 2015 | Pubmed ID: 26084806 Clueless, a Protein Required for Mitochondrial Function, Interacts with the PINK1-Parkin Complex in Drosophila Disease Models & Mechanisms. Jun, 2015 | Pubmed ID: 26035866 Cardiac Deficiency of Single Cytochrome Oxidase Assembly Factor Scox Induces P53-dependent Apoptosis in a Drosophila Cardiomyopathy Model Human Molecular Genetics. Jul, 2015 | Pubmed ID: 25792727 PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase Cell Reports. Mar, 2015 | Pubmed ID: 25753422 Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension American Journal of Respiratory Cell and Molecular Biology. Sep, 2015 | Pubmed ID: 25569851 Drosophila As a Potential Model to Ameliorate Mutant Huntington-mediated Cardiac Amyloidosis Rare Diseases (Austin, Tex.). 2014 | Pubmed ID: 26942103 Cdc42 and Formin Activity Control Non-muscle Myosin Dynamics During Drosophila Heart Morphogenesis The Journal of Cell Biology. Sep, 2014 | Pubmed ID: 25267295 Methods to Assess Drosophila Heart Development, Function and Aging Methods (San Diego, Calif.). Jun, 2014 | Pubmed ID: 24727147 Systems Genomics of Metabolic Phenotypes in Wild-type Drosophila Melanogaster Genetics. Jun, 2014 | Pubmed ID: 24671769 ROS Regulate Cardiac Function Via a Distinct Paracrine Mechanism Cell Reports. Apr, 2014 | Pubmed ID: 24656823 Metabolic and Transcriptional Response to a High-fat Diet in Drosophila Melanogaster Molecular Metabolism. Feb, 2014 | Pubmed ID: 24567903 A Dual Role for Integrin-linked Kinase and β1-integrin in Modulating Cardiac Aging Aging Cell. Jun, 2014 | Pubmed ID: 24400780 Integrin-linked Kinase Modulates Longevity and Thermotolerance in C. Elegans Through Neuronal Control of HSF-1 Aging Cell. Jun, 2014 | Pubmed ID: 24314125 The Role of Pygopus in the Differentiation of Intracardiac Valves in Drosophila Genesis (New York, N.Y. : 2000). Jan, 2014 | Pubmed ID: 24265259 Mechanical and Non-mechanical Functions of Dystrophin Can Prevent Cardiac Abnormalities in Drosophila Experimental Gerontology. Jan, 2014 | Pubmed ID: 24231130 Huntington's Disease Induced Cardiac Amyloidosis is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart PLoS Genetics. 2013 | Pubmed ID: 24367279 Pygopus Maintains Heart Function in Aging Drosophila Independently of Canonical Wnt Signaling Circulation. Cardiovascular Genetics. Oct, 2013 | Pubmed ID: 24046329 Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/robo Activity at the Heart Lumen PLoS Genetics. Jun, 2013 | Pubmed ID: 23825967 Survival Response to Increased Ceramide Involves Metabolic Adaptation Through Novel Regulators of Glycolysis and Lipolysis PLoS Genetics. Jun, 2013 | Pubmed ID: 23818862 Whole-Genome RVISTA: a Tool to Determine Enrichment of Transcription Factor Binding Sites in Gene Promoters from Transcriptomic Data Bioinformatics (Oxford, England). Aug, 2013 | Pubmed ID: 23736530 Complex Genetic Architecture of Cardiac Disease in a Wild Type Inbred Strain of Drosophila Melanogaster PloS One. 2013 | Pubmed ID: 23638165 Declining Signal-dependence of Nrf2-MafS Regulated Gene Expressioncorrelates with Aging Phenotypes Aging Cell. Mar, 2013 | Pubmed ID: 23521918 A Drosophila Model of High Sugar Diet-induced Cardiomyopathy PLoS Genetics. 2013 | Pubmed ID: 23326243 APJ Acts As a Dual Receptor in Cardiac Hypertrophy Nature. Aug, 2012 | Pubmed ID: 22810587 Statin Treatment Increases Lifespan and Improves Cardiac Health in Drosophila by Decreasing Specific Protein Prenylation PloS One. 2012 | Pubmed ID: 22737247 Regulation of Parkin and PINK1 by Neddylation Human Molecular Genetics. Jun, 2012 | Pubmed ID: 22388932 Drosophila As a Model to Study the Genetic Mechanisms of Obesity-Associated Heart Dysfunction Journal of Cellular and Molecular Medicine. Feb, 2012 | Pubmed ID: 22303936 Probing the Polygenic Basis of Cardiomyopathies in Drosophila Journal of Cellular and Molecular Medicine. Jan, 2012 | Pubmed ID: 22268758 Measuring Passive Myocardial Stiffness in Drosophila Melanogaster to Investigate Diastolic Dysfunction Journal of Cellular and Molecular Medicine. Jan, 2012 | Pubmed ID: 22225769 Over-expression of DSCAM and COL6A2 Cooperatively Generates Congenital Heart Defects PLoS Genetics. Nov, 2011 | Pubmed ID: 22072978 Lipotoxicity and Cardiac Dysfunction in Mammals and Drosophila Critical Reviews in Biochemistry and Molecular Biology. Oct, 2011 | Pubmed ID: 21851295 The UNC-45 Chaperone is Critical for Establishing Myosin-based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model PloS One. 2011 | Pubmed ID: 21799905 ATP-sensitive Potassium Channel (K(ATP))-dependent Regulation of Cardiotropic Viral Infections Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21719711 Tinman/Nkx2-5 Acts Via MiR-1 and Upstream of Cdc42 to Regulate Heart Function Across Species The Journal of Cell Biology. Jun, 2011 | Pubmed ID: 21690310 A Mighty Small Heart: the Cardiac Proteome of Adult Drosophila Melanogaster PloS One. 2011 | Pubmed ID: 21541028 Phospholipid Homeostasis and Lipotoxic Cardiomyopathy: a Matter of Balance Fly. Jul-Sep, 2011 | Pubmed ID: 21494094 Phospholipid Homeostasis Regulates Lipid Metabolism and Cardiac Function Through SREBP Signaling in Drosophila Genes & Development. Jan, 2011 | Pubmed ID: 21245170 Drosophila As a Model to Study Cardiac Aging Experimental Gerontology. May, 2011 | Pubmed ID: 21130861 High-fat-diet-induced Obesity and Heart Dysfunction Are Regulated by the TOR Pathway in Drosophila Cell Metabolism. Nov, 2010 | Pubmed ID: 21035763 Sestrins at the Crossroad Between Stress and Aging Aging. Jun, 2010 | Pubmed ID: 20606249 SAMD4B, a Novel SAM-containing Protein, Inhibits AP-1-, P53- and P21-mediated Transcriptional Activity BMB Reports. May, 2010 | Pubmed ID: 20510020 A Global in Vivo Drosophila RNAi Screen Identifies NOT3 As a Conserved Regulator of Heart Function Cell. Apr, 2010 | Pubmed ID: 20371351 Sestrin As a Feedback Inhibitor of TOR That Prevents Age-related Pathologies Science (New York, N.Y.). Mar, 2010 | Pubmed ID: 20203043 KBTBD7, a Novel Human BTB-kelch Protein, Activates Transcriptional Activities of SRE and AP-1 BMB Reports. Jan, 2010 | Pubmed ID: 20132730 D4eBP Acts Downstream of Both DTOR and DFoxo to Modulate Cardiac Functional Aging in Drosophila Aging Cell. Sep, 2009 | Pubmed ID: 19594484 Partial Loss of GATA Factor Pannier Impairs Adult Heart Function in Drosophila Human Molecular Genetics. Sep, 2009 | Pubmed ID: 19494035 A New Method for Detection and Quantification of Heartbeat Parameters in Drosophila, Zebrafish, and Embryonic Mouse Hearts BioTechniques. Feb, 2009 | Pubmed ID: 19317655 Non-autonomous Modulation of Heart Rhythm, Contractility and Morphology in Adult Fruit Flies Developmental Biology. Apr, 2009 | Pubmed ID: 19233157 The Drosophila Homolog of Vertebrate Islet1 is a Key Component in Early Cardiogenesis Development (Cambridge, England). Jan, 2009 | Pubmed ID: 19088091 Transcription Factor Neuromancer/TBX20 is Required for Cardiac Function in Drosophila with Implications for Human Heart Disease Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19074289 A Novel Human BTB-kelch Protein KLHL31, Strongly Expressed in Muscle and Heart, Inhibits Transcriptional Activities of TRE and SRE Molecules and Cells. Nov, 2008 | Pubmed ID: 18719355 Dispensable Role of Drosophila Ortholog of LRRK2 Kinase Activity in Survival of Dopaminergic Neurons Molecular Neurodegeneration. 2008 | Pubmed ID: 18257932 Dystrophin Deficiency in Drosophila Reduces Lifespan and Causes a Dilated Cardiomyopathy Phenotype Aging Cell. Mar, 2008 | Pubmed ID: 18221418 ZNF418, a Novel Human KRAB/C2H2 Zinc Finger Protein, Suppresses MAPK Signaling Pathway Molecular and Cellular Biochemistry. Mar, 2008 | Pubmed ID: 18084723 The Drosophila Muscle LIM Protein, Mlp84B, is Essential for Cardiac Function The Journal of Experimental Biology. Jan, 2008 | Pubmed ID: 18083727 Spatial Specificity of Mesodermal Even-skipped Expression Relies on Multiple Repressor Sites Developmental Biology. Jan, 2008 | Pubmed ID: 18067885 Drosophila Aging 2006/2007 Experimental Gerontology. Jan, 2008 | Pubmed ID: 18061385 Myosin Transducer Mutations Differentially Affect Motor Function, Myofibril Structure, and the Performance of Skeletal and Cardiac Muscles Molecular Biology of the Cell. Feb, 2008 | Pubmed ID: 18045988 Genetic Variation for Cardiac Dysfunction in Drosophila PloS One. 2007 | Pubmed ID: 17622346 Genetic Control of Heart Function and Aging in Drosophila Trends in Cardiovascular Medicine. Jul, 2007 | Pubmed ID: 17574126 KCNQ Potassium Channel Mutations Cause Cardiac Arrhythmias in Drosophila That Mimic the Effects of Aging Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360457 Cardiac Aging Seminars in Cell & Developmental Biology. Feb, 2007 | Pubmed ID: 17275368 Age-related Cardiac Deterioration: Insights from Drosophila Frontiers in Bioscience : a Journal and Virtual Library. 2007 | Pubmed ID: 17127282 Age-related Cardiac Disease Model of Drosophila Mechanisms of Ageing and Development. Jan, 2007 | Pubmed ID: 17125816 Drosophila Aging 2005/06 Experimental Gerontology. Dec, 2006 | Pubmed ID: 17126511 Cardioblast-intrinsic Tinman Activity Controls Proper Diversification and Differentiation of Myocardial Cells in Drosophila Development (Cambridge, England). Oct, 2006 | Pubmed ID: 16987868 Functional Conservation of Zinc-finger Homeodomain Gene Zfh1/SIP1 in Drosophila Heart Development Development Genes and Evolution. Nov, 2006 | Pubmed ID: 16957952 Antioxidants Protect PINK1-dependent Dopaminergic Neurons in Drosophila Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16938835 Activated FOXO-mediated Insulin Resistance is Blocked by Reduction of TOR Activity Cell Metabolism. Aug, 2006 | Pubmed ID: 16890541 The ATP-sensitive Potassium (KATP) Channel-encoded DSUR Gene is Required for Drosophila Heart Function and is Regulated by Tinman Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16882722 Images in Cardiovascular Medicine: in Vivo Imaging of the Adult Drosophila Melanogaster Heart with Real-time Optical Coherence Tomography Circulation. Jul, 2006 | Pubmed ID: 16831991 Role of Svp in Drosophila Pericardial Cell Growth Yi Chuan Xue Bao = Acta Genetica Sinica. Jan, 2006 | Pubmed ID: 16450585 Hedgehog and RAS Pathways Cooperate in the Anterior-posterior Specification and Positioning of Cardiac Progenitor Cells Developmental Biology. Feb, 2006 | Pubmed ID: 16387294 Slit and Robo Control Cardiac Cell Polarity and Morphogenesis Current Biology : CB. Dec, 2005 | Pubmed ID: 16360689 Embryonic Even Skipped-dependent Muscle and Heart Cell Fates Are Required for Normal Adult Activity, Heart Function, and Lifespan Circulation Research. Nov, 2005 | Pubmed ID: 16239588 Identification of Genetic Loci That Interact with Cut During Drosophila Wing-margin Development Genetics. Aug, 2005 | Pubmed ID: 15956666 Neuromancer Tbx20-related Genes (H15/midline) Promote Cell Fate Specification and Morphogenesis of the Drosophila Heart Developmental Biology. Mar, 2005 | Pubmed ID: 15733676 Insulin Regulation of Heart Function in Aging Fruit Flies Nature Genetics. Dec, 2004 | Pubmed ID: 15565107 Drosophila, an Emerging Model for Cardiac Disease Gene. Nov, 2004 | Pubmed ID: 15527959 Screening Assays for Heart Function Mutants in Drosophila BioTechniques. Jul, 2004 | Pubmed ID: 15283201 Dynamics of Cux2 Expression Suggests That an Early Pool of SVZ Precursors is Fated to Become Upper Cortical Layer Neurons Cerebral Cortex (New York, N.Y. : 1991). Dec, 2004 | Pubmed ID: 15238450 Myogenic Cells Fates Are Antagonized by Notch Only in Asymmetric Lineages of the Drosophila Heart, with or Without Cell Division Development (Cambridge, England). Jul, 2003 | Pubmed ID: 12756185 Gata Factor Pannier is Required to Establish Competence for Heart Progenitor Formation Development (Cambridge, England). Jul, 2003 | Pubmed ID: 12756184 AmphiNk2-tin, an Amphioxus Homeobox Gene Expressed in Myocardial Progenitors: Insights into Evolution of the Vertebrate Heart Developmental Biology. Mar, 2003 | Pubmed ID: 12618138 Transcriptional Integration of Competence Modulated by Mutual Repression Generates Cell-type Specificity Within the Cardiogenic Mesoderm Developmental Biology. Dec, 2002 | Pubmed ID: 12482712 The Patterns of Wingless, Decapentaplegic, and Tinman Position the Drosophila Heart Mechanisms of Development. Jun, 2002 | Pubmed ID: 12175486 MBLR, a New RING Finger Protein Resembling Mammalian Polycomb Gene Products, is Regulated by Cell Cycle-dependent Phosphorylation Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Aug, 2002 | Pubmed ID: 12167161 The Bereft Gene, a Potential Target of the Neural Selector Gene Cut, Contributes to Bristle Morphogenesis Genetics. May, 2002 | Pubmed ID: 12019237 [The Use of RNAi As a Technique to Study the Functions of Heart-related Genes in Drosophila] Yi Chuan Xue Bao = Acta Genetica Sinica. Jan, 2002 | Pubmed ID: 11838373 A Late Role for a Subset of Neurogenic Genes to Limit Sensory Precursor Recruitments in Drosophila Embryos Roux's Archives of Developmental Biology : the Official Organ of the EDBO. Aug, 1993 | Pubmed ID: 28306050 Morphological Differentiation of the Embryonic Peripheral Neurons in Drosophila Roux's Archives of Developmental Biology : the Official Organ of the EDBO. Feb, 1987 | Pubmed ID: 28305460 उच्च वसा आहार खिलाने और उच्च प्रवाह Triacylglyceride परख में Drosophila Melanogaster Soda Balla Diop1, Ryan T. Birse1, Rolf Bodmer1 1Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute JoVE 56029 Genetics के फ्लोरोसेंट लेबलिंग ड्रोसोफिला हार्ट संरचनाएं Nakissa N. Alayari1,2, Georg Vogler2, Ouarda Taghli-Lamallem2, Karen Ocorr2, Rolf Bodmer2, Anthony Cammarato1,2 1Biology Department, San Diego State University, 2Development and Aging Program, NASCR Center, The Sanford Burnham Institute for Medical Research JoVE 1423 Biology छोटे दिल की अर्ध स्वचालित ऑप्टिकल हार्टबीट विश्लेषण Karen Ocorr1, Martin Fink2, Anthony Cammarato1,3, Sanford I. Bernstein3, Rolf Bodmer1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research, 2Cardiac Electrophysiology Group, Dept. of Physiology, Anatomy and Genetics, The Sanford Burnham Institute for Medical Research, 3Biology Department and Heart Institute, San Diego State University JoVE 1435 Biology
उच्च वसा आहार खिलाने और उच्च प्रवाह Triacylglyceride परख में Drosophila Melanogaster Soda Balla Diop1, Ryan T. Birse1, Rolf Bodmer1 1Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute JoVE 56029 Genetics
के फ्लोरोसेंट लेबलिंग ड्रोसोफिला हार्ट संरचनाएं Nakissa N. Alayari1,2, Georg Vogler2, Ouarda Taghli-Lamallem2, Karen Ocorr2, Rolf Bodmer2, Anthony Cammarato1,2 1Biology Department, San Diego State University, 2Development and Aging Program, NASCR Center, The Sanford Burnham Institute for Medical Research JoVE 1423 Biology
छोटे दिल की अर्ध स्वचालित ऑप्टिकल हार्टबीट विश्लेषण Karen Ocorr1, Martin Fink2, Anthony Cammarato1,3, Sanford I. Bernstein3, Rolf Bodmer1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research, 2Cardiac Electrophysiology Group, Dept. of Physiology, Anatomy and Genetics, The Sanford Burnham Institute for Medical Research, 3Biology Department and Heart Institute, San Diego State University JoVE 1435 Biology
