Ryan McBride Department of Cell and Molecular Biology, Chemical Physiology and Microbial Science The Scripps Research Institute Biography Publications Institution JoVE Articles Ryan McBride has not added a biography. If you are Ryan McBride and would like to personalize this page please email our Author Liaison for assistance. Publications Amino Acid Residues at Positions 222 and 227 of the Hemagglutinin Together with the Neuraminidase Determine Binding of H5 Avian Influenza Viruses to Sialyl Lewis X Archives of Virology. Feb, 2016 | Pubmed ID: 26542967 Low-Cost Peptide Microarrays for Mapping Continuous Antibody Epitopes Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26490468 Identification of Stabilizing Mutations in an H5 Hemagglutinin Influenza Virus Protein Journal of Virology. 2015 | Pubmed ID: 26719265 Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man The Journal of Biological Chemistry. Dec, 2015 | Pubmed ID: 26507663 Changes to the Dynamic Nature of Hemagglutinin and the Emergence of the 2009 Pandemic H1N1 Influenza Virus Scientific Reports. 2015 | Pubmed ID: 26269288 Recognition of Microbial Glycans by Human Intelectin-1 Nature Structural & Molecular Biology. Aug, 2015 | Pubmed ID: 26148048 Antibody Microarrays Utilizing Site-specific Antibody-oligonucleotide Conjugates Bioconjugate Chemistry. May, 2015 | Pubmed ID: 25884500 Mammalian Adaptation of Influenza A(H7N9) Virus is Limited by a Narrow Genetic Bottleneck Nature Communications. 2015 | Pubmed ID: 25850788 A Human-infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors Cell Host & Microbe. Mar, 2015 | Pubmed ID: 25766296 Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus Cell Host & Microbe. Mar, 2015 | Pubmed ID: 25766295 Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies Cell. Sep, 2014 | Pubmed ID: 25259921 Circulating Avian Influenza Viruses Closely Related to the 1918 Virus Have Pandemic Potential Cell Host & Microbe. Jun, 2014 | Pubmed ID: 24922572 Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas Chemical Science (Royal Society of Chemistry : 2010). Jun, 2014 | Pubmed ID: 24921038 Microbial Glycan Microarrays Define Key Features of Host-microbial Interactions Nature Chemical Biology. Jun, 2014 | Pubmed ID: 24814672 Broadly Neutralizing HIV Antibodies Define a Glycan-dependent Epitope on the Prefusion Conformation of Gp41 on Cleaved Envelope Trimers Immunity. May, 2014 | Pubmed ID: 24768347 MIRAGE: the Minimum Information Required for a Glycomics Experiment Glycobiology. May, 2014 | Pubmed ID: 24653214 Optimization of Peptide Arrays for Studying Antibodies to Hepatitis C Virus Continuous Epitopes Journal of Immunological Methods. Jan, 2014 | Pubmed ID: 24269751 Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-transmissible H5N1 Viruses Journal of Virology. Jan, 2014 | Pubmed ID: 24173215 Preferential Recognition of Avian-like Receptors in Human Influenza A H7N9 Viruses Science (New York, N.Y.). Dec, 2013 | Pubmed ID: 24311689 Synthesis of Biologically Active N- and O-linked Glycans with Multisialylated Poly-N-acetyllactosamine Extensions Using P. Damsela α2-6 Sialyltransferase Journal of the American Chemical Society. Dec, 2013 | Pubmed ID: 24256304 New World Bats Harbor Diverse Influenza a Viruses PLoS Pathogens. Oct, 2013 | Pubmed ID: 24130481 Evolution of the Hemagglutinin Protein of the New Pandemic H1N1 Influenza Virus: Maintaining Optimal Receptor Binding by Compensatory Substitutions Journal of Virology. Dec, 2013 | Pubmed ID: 24109242 A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody Against the A/Goose/Guangdong/1/96 Hemagglutinin Journal of Virology. Dec, 2013 | Pubmed ID: 24049169 A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N-glycans Science (New York, N.Y.). Jul, 2013 | Pubmed ID: 23888036 Characterization of H7N9 Influenza A Viruses Isolated from Humans Nature. Sep, 2013 | Pubmed ID: 23842494 Supersite of Immune Vulnerability on the Glycosylated Face of HIV-1 Envelope Glycoprotein Gp120 Nature Structural & Molecular Biology. Jul, 2013 | Pubmed ID: 23708606 Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding Via Recognition of the HIV-1 Gp120 V3 Base and Multiple Surrounding Glycans PLoS Pathogens. May, 2013 | Pubmed ID: 23658524 On-Chip Synthesis and Screening of a Sialoside Library Yields a High Affinity Ligand for Siglec-7 ACS Chemical Biology. Apr, 2013 | Pubmed ID: 23597400 A Recurring Motif for Antibody Recognition of the Receptor-binding Site of Influenza Hemagglutinin Nature Structural & Molecular Biology. Mar, 2013 | Pubmed ID: 23396351 The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Improving the Standards for Reporting Mass-spectrometry-based Glycoanalytic Data Molecular & Cellular Proteomics : MCP. Apr, 2013 | Pubmed ID: 23378518 Hemagglutinin Homologue from H17N10 Bat Influenza Virus Exhibits Divergent Receptor-binding and PH-dependent Fusion Activities Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23297216 Metformin Compared with Insulin in the Treatment of Pregnant Women with Overt Diabetes: A Randomized Controlled Trial American Journal of Perinatology. Oct, 2012 | Pubmed ID: 23096052 Click and Pick: Identification of Sialoside Analogues for Siglec-based Cell Targeting Angewandte Chemie (International Ed. in English). Oct, 2012 | Pubmed ID: 23038623 Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors Journal of Virology. Dec, 2012 | Pubmed ID: 23015718 Functional Balance of the Hemagglutinin and Neuraminidase Activities Accompanies the Emergence of the 2009 H1N1 Influenza Pandemic Journal of Virology. Sep, 2012 | Pubmed ID: 22718832 A Siglec-like Sialic-acid-binding Motif Revealed in an Adenovirus Capsid Protein Glycobiology. Aug, 2012 | Pubmed ID: 22522600 Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-linked Glycans by Human and Avian Influenza A Virus Hemagglutinins Angewandte Chemie (International Ed. in English). May, 2012 | Pubmed ID: 22505324 In Situ Electroporation of Surface-bound SiRNAs in Microwell Arrays Lab on a Chip. Mar, 2012 | Pubmed ID: 22245984 Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic Journal of Virology. Jan, 2012 | Pubmed ID: 22072785 A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield Science (New York, N.Y.). Nov, 2011 | Pubmed ID: 21998254 Improved Premenstrual Syndrome Symptoms After NovaSure Endometrial Ablation Journal of Minimally Invasive Gynecology. Sep-Oct, 2011 | Pubmed ID: 21872168 Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans Through a Single Binding Site Journal of Molecular Biology. Jan, 2011 | Pubmed ID: 21112338 Production and Application of Glycan Microarrays Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20217584 Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic Journal of Virology. Feb, 2010 | Pubmed ID: 20007271 Highly Parallel Introduction of Nucleic Acids into Mammalian Cells Grown in Microwell Arrays Lab on a Chip. Dec, 2009 | Pubmed ID: 20024036 The Perception of 3-D Shape from Shadows Cast Onto Curved Surfaces Acta Psychologica. May, 2009 | Pubmed ID: 19264291 Contemporary North American Influenza H7 Viruses Possess Human Receptor Specificity: Implications for Virus Transmissibility Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18508975 Visual Discrimination of Local Surface Structure: Slant, Tilt, and Curvedness Vision Research. Mar, 2006 | Pubmed ID: 16289208 Molecular Evolution of the Escherichia Coli Chromosome. VI. Two Regions of High Effective Recombination Genetics. Feb, 2003 | Pubmed ID: 12618387 A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins Ryan McBride1, James C. Paulson1, Robert P. de Vries1,2 1Department of Cell and Molecular Biology, Chemical Physiology and Microbial Science, The Scripps Research Institute, 2Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University JoVE 53847 Immunology and Infection
A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins Ryan McBride1, James C. Paulson1, Robert P. de Vries1,2 1Department of Cell and Molecular Biology, Chemical Physiology and Microbial Science, The Scripps Research Institute, 2Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University JoVE 53847 Immunology and Infection
