Sabine Gerbal-Chaloin

Publications

• Activation of the Constitutive Androstane Receptor Induces Hepatic Lipogenesis and Regulates Pnpla3 Gene Expression in a LXR-independent Way
  Toxicology and Applied Pharmacology. Jul, 2016  |   Pubmed ID: 27180240
• Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes
  PloS One. 2016  |   Pubmed ID: 27138278
• The Pregnane X Receptor Down-regulates Organic Cation Transporter 1 (SLC22A1) in Human Hepatocytes by Competing for ("squelching") SRC-1 Coactivator
  British Journal of Pharmacology. May, 2016  |   Pubmed ID: 26920453
• Synergistic Activation of Human Pregnane X Receptor by Binary Cocktails of Pharmaceutical and Environmental Compounds
  Nature Communications. Sep, 2015  |   Pubmed ID: 26333997
• Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling
  Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2015  |   Pubmed ID: 26259606
• PBPK Modeling of Irbesartan: Incorporation of Hepatic Uptake
  Biopharmaceutics & Drug Disposition. Nov, 2015  |   Pubmed ID: 26037524
• Novel Role for Carbohydrate Responsive Element Binding Protein in the Control of Ethanol Metabolism and Susceptibility to Binge Drinking
  Hepatology (Baltimore, Md.). Oct, 2015  |   Pubmed ID: 25761756
• Cold Preservation of Human Adult Hepatocytes for Liver Cell Therapy
  Cell Transplantation. 2015  |   Pubmed ID: 25622096
• The WNT/β-catenin Pathway is a Transcriptional Regulator of CYP2E1, CYP1A2, and Aryl Hydrocarbon Receptor Gene Expression in Primary Human Hepatocytes
  Molecular Pharmacology. Dec, 2014  |   Pubmed ID: 25228302
• Human Induced Pluripotent Stem Cells in Hepatology: Beyond the Proof of Concept
  The American Journal of Pathology. Feb, 2014  |   Pubmed ID: 24269594
• Nuclear Receptors in the Cross-talk of Drug Metabolism and Inflammation
  Drug Metabolism Reviews. Feb, 2013  |   Pubmed ID: 23330545
• Dissecting the First Transcriptional Divergence During Human Embryonic Development
  Stem Cell Reviews. Mar, 2012  |   Pubmed ID: 21750961
• Brief Report: Benchmarking Human Pluripotent Stem Cell Markers During Differentiation into the Three Germ Layers Unveils a Striking Heterogeneity: All Markers Are Not Equal
  Stem Cells (Dayton, Ohio). Sep, 2011  |   Pubmed ID: 21714037
• Chromatin Dynamics of Gene Activation and Repression in Response to Interferon Alpha (IFN(alpha)) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor STAT2
  The Journal of Biological Chemistry. Jun, 2011  |   Pubmed ID: 21498520
• Modular Bioreactor for Primary Human Hepatocyte Culture: Medium Flow Stimulates Expression and Activity of Detoxification Genes
  Biotechnology Journal. May, 2011  |   Pubmed ID: 21259441
• Comparison of Hepatic-like Cell Production from Human Embryonic Stem Cells and Adult Liver Progenitor Cells: CAR Transduction Activates a Battery of Detoxification Genes
  Stem Cell Reviews. Sep, 2011  |   Pubmed ID: 21210253
• Human Pluripotent Stem Cells: from Biology to Cell Therapy
  World Journal of Stem Cells. Apr, 2010  |   Pubmed ID: 21607113
• Isolation and Culture of Adult Human Liver Progenitor Cells: in Vitro Differentiation to Hepatocyte-like Cells
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20645055
• Comparative Effects of Microtubules Disruption on Glucocorticoid Receptor Functions in Proliferating and Quiescent Cells
  International Journal of Toxicology. May-Jun, 2010  |   Pubmed ID: 20448266
• The Tangle of Nuclear Receptors That Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences
  Annual Review of Pharmacology and Toxicology. 2008  |   Pubmed ID: 17608617
• Isolation, Characterization, and Differentiation to Hepatocyte-like Cells of Nonparenchymal Epithelial Cells from Adult Human Liver
  Stem Cells (Dayton, Ohio). Jul, 2007  |   Pubmed ID: 17412893
• First Step of the Cell-penetrating Peptide Mechanism Involves Rac1 GTPase-dependent Actin-network Remodelling
  Biology of the Cell. Apr, 2007  |   Pubmed ID: 17233629
• Ketoconazole and Miconazole Are Antagonists of the Human Glucocorticoid Receptor: Consequences on the Expression and Function of the Constitutive Androstane Receptor and the Pregnane X Receptor
  Molecular Pharmacology. Jul, 2006  |   Pubmed ID: 16608920
• Is Nuclear Factor Kappa-B the Missing Link Between Inflammation, Cancer and Alteration in Hepatic Drug Metabolism in Patients with Cancer?
  European Journal of Cancer (Oxford, England : 1990). Apr, 2006  |   Pubmed ID: 16510279
• Role of CYP3A4 in the Regulation of the Aryl Hydrocarbon Receptor by Omeprazole Sulphide
  Cellular Signalling. May, 2006  |   Pubmed ID: 16109480
• Design of a Novel Class of Peptide Inhibitors of Cyclin-dependent Kinase/cyclin Activation
  The Journal of Biological Chemistry. Apr, 2005  |   Pubmed ID: 15649889
• On the Mechanism of Non-endosomial Peptide-mediated Cellular Delivery of Nucleic Acids
  Biochimica Et Biophysica Acta. Dec, 2004  |   Pubmed ID: 15581849
• Interleukin 1beta Inhibits CAR-induced Expression of Hepatic Genes Involved in Drug and Bilirubin Clearance
  Hepatology (Baltimore, Md.). Oct, 2004  |   Pubmed ID: 15382119
• Pathophysiological Factors Affecting CAR Gene Expression
  Drug Metabolism Reviews. Nov, 2003  |   Pubmed ID: 14705859
• Use of Long-term Cultures of Human Hepatocytes to Study Cytochrome P450 Gene Expression
  Methods in Enzymology. 2002  |   Pubmed ID: 12424921
• Transcriptional Regulation of CYP2C9 Gene. Role of Glucocorticoid Receptor and Constitutive Androstane Receptor
  The Journal of Biological Chemistry. Jan, 2002  |   Pubmed ID: 11679585