Sacha Zeerleder Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Center University of Amsterdam Biography Publications Institution JoVE Articles Sacha Zeerleder has not added a biography. If you are Sacha Zeerleder and would like to personalize this page please email our Author Liaison for assistance. Publications Cooperation of Factor VII-activating Protease and Serum Deoxyribonuclease I in Release of Nucleosomes from Necrotic Cells Arthritis and Rheumatism. Nov, 2013 | Pubmed ID: 24248834 Evaluating the Efficacy of Subcutaneous C1-esterase Inhibitor Administration for Use in Rat Models of Inflammatory Diseases Drug Delivery. Nov, 2013 | Pubmed ID: 24215253 Nucleosomes and Neutrophil Activation in Sickle Cell Disease Painful Crisis Haematologica. Nov, 2013 | Pubmed ID: 23911704 C1-esterase Inhibitor Concentrate Rescues Erythrocytes from Complement-mediated Destruction in Autoimmune Hemolytic Anemia Blood. Feb, 2013 | Pubmed ID: 23411737 Circulating Nucleosomes and Neutrophil Activation As Risk Factors for Deep Vein Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2013 | Pubmed ID: 23104849 Intrabronchial Activated Protein C Enhances Lipopolysaccharide-induced Pulmonary Responses The European Respiratory Journal. Jul, 2013 | Pubmed ID: 23060625 Circulating Nucleosomes and Severity of Illness in Children Suffering from Meningococcal Sepsis Treated with Protein C Critical Care Medicine. Dec, 2012 | Pubmed ID: 22932399 Transfusion-related Acute Lung Injury in Cardiac Surgery Patients is Characterized by Pulmonary Inflammation and Coagulopathy: a Prospective Nested Case-control Study Critical Care Medicine. Oct, 2012 | Pubmed ID: 22824931 Aleukemic Variant of Mast Cell Leukemia Blood. Mar, 2012 | Pubmed ID: 22482127 Prolonged C1 Inhibitor Administration Improves Local Healing of Burn Wounds and Reduces Myocardial Inflammation in a Rat Burn Wound Model Journal of Burn Care & Research : Official Publication of the American Burn Association. Jul-Aug, 2012 | Pubmed ID: 22447201 Factor VII-activating Protease is Activated in Multiple Trauma Patients and Generates Anaphylatoxin C5a Journal of Immunology (Baltimore, Md. : 1950). Mar, 2012 | Pubmed ID: 22308306 C1-esterase Inhibitor Protects Against Early Vein Graft Remodeling Under Arterial Blood Pressure Atherosclerosis. Jan, 2012 | Pubmed ID: 22078245 C1-inhibitor: More Than a Serine Protease Inhibitor Seminars in Thrombosis and Hemostasis. Jun, 2011 | Pubmed ID: 21805442 Activation of Factor VII-activating Protease in Human Inflammation: a Sensor for Cell Death Critical Care (London, England). 2011 | Pubmed ID: 21466697 CD44 is Protective During Hyperoxia-induced Lung Injury American Journal of Respiratory Cell and Molecular Biology. Mar, 2011 | Pubmed ID: 20463290 Nucleosome-releasing Factor: a New Role for Factor VII-activating Protease (FSAP) FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2008 | Pubmed ID: 18753248 C1 Inhibitor: Just a Serine Protease Inhibitor? New and Old Considerations on Therapeutic Applications of C1 Inhibitor Expert Opinion on Biological Therapy. Aug, 2008 | Pubmed ID: 18613773 A Plasma Nucleosome Releasing Factor (NRF) with Serine Protease Activity is Instrumental in Removal of Nucleosomes from Secondary Necrotic Cells FEBS Letters. Nov, 2007 | Pubmed ID: 17976375 Factor XIII in Severe Sepsis and Septic Shock Thrombosis Research. 2007 | Pubmed ID: 16574200 The Effects of Continuous Venovenous Hemofiltration on Coagulation Activation Critical Care (London, England). 2006 | Pubmed ID: 17069648 International Society on Thrombosis and Haemostasis Score for Overt Disseminated Intravascular Coagulation Predicts Organ Dysfunction and Fatality in Sepsis Patients Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis. Sep, 2006 | Pubmed ID: 16905947 The Struggle to Detect Circulating DNA Critical Care (London, England). 2006 | Pubmed ID: 16719935 TAFI and PAI-1 Levels in Human Sepsis Thrombosis Research. 2006 | Pubmed ID: 16009400 Disseminated Intravascular Coagulation in Sepsis Chest. Oct, 2005 | Pubmed ID: 16236964 Comment on Hemostatic Markers and the Sepsis-related Organ Failure Assessment Score in Patients with Disseminated Intravascular Coagulation in an Intensive Care Unit by Okabayashi Et Al American Journal of Hematology. Aug, 2005 | Pubmed ID: 16044451 Activated Cytotoxic T Cells and NK Cells in Severe Sepsis and Septic Shock and Their Role in Multiple Organ Dysfunction Clinical Immunology (Orlando, Fla.). Aug, 2005 | Pubmed ID: 15993363 Administration of C1 Inhibitor Reduces Neutrophil Activation in Patients with Sepsis Clinical and Diagnostic Laboratory Immunology. Jul, 2003 | Pubmed ID: 12853381 Elevated Nucleosome Levels in Systemic Inflammation and Sepsis Critical Care Medicine. Jul, 2003 | Pubmed ID: 12847387 Evaluation of a Platelet Function Analyser (PFA-100) in Patients with a Bleeding Tendency Swiss Medical Weekly. Aug, 2002 | Pubmed ID: 12457302 C1-inhibitor in Patients with Severe Sepsis and Septic Shock: Beneficial Effect on Renal Dysfunction Critical Care Medicine. Aug, 2002 | Pubmed ID: 12163783 Effect of Low-molecular Weight Dextran Sulfate on Coagulation and Platelet Function Tests Thrombosis Research. Mar, 2002 | Pubmed ID: 12062546 Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells Elisabeth M. Meulenbroek1, Diana Wouters1, Sacha Zeerleder1,2 1Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Center, University of Amsterdam, 2Department of Hematology, Academic Medical Center, University of Amsterdam JoVE 51161 Immunology and Infection
Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells Elisabeth M. Meulenbroek1, Diana Wouters1, Sacha Zeerleder1,2 1Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Center, University of Amsterdam, 2Department of Hematology, Academic Medical Center, University of Amsterdam JoVE 51161 Immunology and Infection