Shaun R. Brinsmade Department of Biology Georgetown University Biography Publications Institution JoVE Articles Shaun R. Brinsmade has not added a biography. If you are Shaun R. Brinsmade and would like to personalize this page please email our Author Liaison for assistance. Publications Guanine Limitation Results in CodY-dependent and -independent Alteration of Physiology and Gene Expression Journal of Bacteriology. Apr, 2018 | Pubmed ID: 29712876 Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus Aureus Journal of Bacteriology. 04, 2018 | Pubmed ID: 29378891 CodY, a Master Integrator of Metabolism and Virulence in Gram-positive Bacteria Current Genetics. Oct, 2016 | Pubmed ID: 27744611 A Spectrum of CodY Activities Drives Metabolic Reorganization and Virulence Gene Expression in Staphylococcus Aureus Molecular Microbiology. Aug, 2016 | Pubmed ID: 27116338 Intermediate Levels of Bacillus Subtilis CodY Activity Are Required for Derepression of the Branched-Chain Amino Acid Permease, BraB PLoS Genetics. Oct, 2015 | Pubmed ID: 26473603 Genome Sequence of the Clinical Isolate Staphylococcus Aureus Subsp. Aureus Strain UAMS-1 Genome Announcements. Feb, 2015 | Pubmed ID: 25676774 Hierarchical Expression of Genes Controlled by the Bacillus Subtilis Global Regulatory Protein CodY Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24843172 GTP Dysregulation in Bacillus Subtilis Cells Lacking (p)ppGpp Results in Phenotypic Amino Acid Auxotrophy and Failure to Adapt to Nutrient Downshift and Regulate Biosynthesis Genes Journal of Bacteriology. Jan, 2014 | Pubmed ID: 24163341 Dissecting Complex Metabolic Integration Provides Direct Genetic Evidence for CodY Activation by Guanine Nucleotides Journal of Bacteriology. Oct, 2011 | Pubmed ID: 21856856 Involvement of Protein Acetylation in Glucose-induced Transcription of a Stress-responsive Promoter Molecular Microbiology. Sep, 2011 | Pubmed ID: 21696463 Regulation of CodY Activity Through Modulation of Intracellular Branched-chain Amino Acid Pools Journal of Bacteriology. Dec, 2010 | Pubmed ID: 20935095 In Vivo and in Vitro Analyses of Single-amino Acid Variants of the Salmonella Enterica Phosphotransacetylase Enzyme Provide Insights into the Function of Its N-terminal Domain The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17339319 Mutation of Phosphotransacetylase but Not Isocitrate Lyase Reduces the Virulence of Salmonella Enterica Serovar Typhimurium in Mice Infection and Immunity. Apr, 2006 | Pubmed ID: 16552088 Minimal Functions and Physiological Conditions Required for Growth of Salmonella Enterica on Ethanolamine in the Absence of the Metabolosome Journal of Bacteriology. Dec, 2005 | Pubmed ID: 16291677 The EutD Gene of Salmonella Enterica Encodes a Protein with Phosphotransacetylase Enzyme Activity Journal of Bacteriology. Mar, 2004 | Pubmed ID: 14996820 The Crystal Structure of Phosphonate-inhibited D-Ala-D-Ala Peptidase Reveals an Analogue of a Tetrahedral Transition State Biochemistry. Feb, 2003 | Pubmed ID: 12564922 A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues Ranjan K. Behera1, Kevin D. Mlynek1, Matthew S. Linz1, Shaun R. Brinsmade1 1Department of Biology, Georgetown University JoVE 59055 Genetics A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus David J. Samuels1, Zhe Wang2, Kyu Y. Rhee2,3, Shaun R. Brinsmade1 1Department of Biology, Georgetown University, 2Division of Infectious Diseases, Weill Cornell Medical College, 3Department of Medicine, Weill Cornell Medical College JoVE 55558 Biochemistry
A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues Ranjan K. Behera1, Kevin D. Mlynek1, Matthew S. Linz1, Shaun R. Brinsmade1 1Department of Biology, Georgetown University JoVE 59055 Genetics
A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus David J. Samuels1, Zhe Wang2, Kyu Y. Rhee2,3, Shaun R. Brinsmade1 1Department of Biology, Georgetown University, 2Division of Infectious Diseases, Weill Cornell Medical College, 3Department of Medicine, Weill Cornell Medical College JoVE 55558 Biochemistry
