Simon C. Watkins Department of Cell Biology and Physiology University of Pittsburgh School of Medicine Biography Publications Institution JoVE Articles Simon C. Watkins has not added a biography. If you are Simon C. Watkins and would like to personalize this page please email our Author Liaison for assistance. Publications Mechanism of Aortic Medial Matrix Remodeling is Distinct in Patients with Bicuspid Aortic Valve The Journal of Thoracic and Cardiovascular Surgery. Jun, 2013 | Pubmed ID: 23764410 Interaction Between Her2 and Beclin-1 Underlies a New Mechanism of Reciprocal Regulation The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23703612 Regulated Recycling of Mutant CFTR is Partially Restored by Pharmacological Treatment Journal of Cell Science. Jun, 2013 | Pubmed ID: 23572510 PEX7 and EBP50 Target INOS to the Peroxisome in Hepatocytes Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. May, 2013 | Pubmed ID: 23474170 Regional Structural and Biomechanical Alterations of the Ovine Main Pulmonary Artery During Postnatal Growth Journal of Biomechanical Engineering. Feb, 2013 | Pubmed ID: 23445067 Automated Imaging System for Fast Quantitation of Neurons, Cell Morphology and Neurite Morphometry in Vivo and in Vitro Neurobiology of Disease. Jun, 2013 | Pubmed ID: 23220621 GENE EXPRESSION AND COLLAGEN FIBER MICROMECHANICAL INTERACTIONS OF THE SEMILUNAR HEART VALVE INTERSTITIAL CELL Cellular and Molecular Bioengineering. Sep, 2012 | Pubmed ID: 23162672 Hydrogels Derived from Central Nervous System Extracellular Matrix Biomaterials. Nov, 2012 | Pubmed ID: 23158935 Mitochondrial Hyperfusion Induced by Loss of Fission Protein Drp1 Causes ATM-dependent G2/M Arrest and Aneuploidy Through DNA Replication Stress Journal of Cell Science. Sep, 2012 | Pubmed ID: 23015593 Dynamin- and Rab5-Dependent Endocytosis of a Ca(2+)-Activated K(+) Channel, KCa2.3 PloS One. 2012 | Pubmed ID: 22952906 High Resolution Imaging of Vascular Function in Zebrafish PloS One. 2012 | Pubmed ID: 22952858 Quantitative Proteomics Reveal ATM Kinase-dependent Exchange in DNA Damage Response Complexes Journal of Proteome Research. Sep, 2012 | Pubmed ID: 22909323 NF-κB Inhibition Delays DNA Damage-induced Senescence and Aging in Mice The Journal of Clinical Investigation. Jul, 2012 | Pubmed ID: 22706308 Obesity-induced Tissue Free Radical Generation: an in Vivo Immuno-spin Trapping Study Free Radical Biology & Medicine. Apr, 2012 | Pubmed ID: 22564528 Impaired Clearance and Enhanced Pulmonary Inflammatory/fibrotic Response to Carbon Nanotubes in Myeloperoxidase-deficient Mice PloS One. 2012 | Pubmed ID: 22479306 Genetically Encoded PH Sensor for Tracking Surface Proteins Through Endocytosis Angewandte Chemie (International Ed. in English). May, 2012 | Pubmed ID: 22461279 The Apoptotic Engulfment Protein Ced-6 Participates in Clathrin-mediated Yolk Uptake in Drosophila Egg Chambers Molecular Biology of the Cell. May, 2012 | Pubmed ID: 22398720 Pharmacological Rescue of the Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Detected by Use of a Novel Fluorescence Platform Molecular Medicine (Cambridge, Mass.). Feb, 2012 | Pubmed ID: 22396015 P53/HMGB1 Complexes Regulate Autophagy and Apoptosis Cancer Research. Apr, 2012 | Pubmed ID: 22345153 Allele Specific Transactivation of Matrix Metalloproteinase 7 by FOXA2 and Correlation with Plasma Levels in Idiopathic Pulmonary Fibrosis American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2012 | Pubmed ID: 22268124 The Engineering of Organized Human Corneal Tissue Through the Spatial Guidance of Corneal Stromal Stem Cells Biomaterials. Feb, 2012 | Pubmed ID: 22078813 Mechanism of Transfer of Functional MicroRNAs Between Mouse Dendritic Cells Via Exosomes Blood. Jan, 2012 | Pubmed ID: 22031862 Direct Visualization of HIV-1 with Correlative Live-cell Microscopy and Cryo-electron Tomography Structure (London, England : 1993). Nov, 2011 | Pubmed ID: 22078557 Functional Characterization of an ScFv-Fc Antibody That Immunotherapeutically Targets the Common Cancer Cell Surface Proteoglycan CSPG4 Cancer Research. Dec, 2011 | Pubmed ID: 22021902 Dynamic Na+-H+ Exchanger Regulatory Factor-1 Association and Dissociation Regulate Parathyroid Hormone Receptor Trafficking at Membrane Microdomains The Journal of Biological Chemistry. Oct, 2011 | Pubmed ID: 21832055 Are Mitochondrial Reactive Oxygen Species Required for Autophagy? Biochemical and Biophysical Research Communications. Aug, 2011 | Pubmed ID: 21806968 Complement Proteins C3 and C4 Bind to Collagen and Elastin in the Vascular Wall: a Potential Role in Vascular Stiffness and Atherosclerosis Clinical and Translational Science. Jun, 2011 | Pubmed ID: 21707943 Streptolysin O Clearance Through Sequestration into Blebs That Bud Passively from the Plasma Membrane Journal of Cell Science. Jul, 2011 | Pubmed ID: 21693578 Extracellular Superoxide Dismutase in Macrophages Augments Bacterial Killing by Promoting Phagocytosis The American Journal of Pathology. Jun, 2011 | Pubmed ID: 21641397 A Role for Zinc in Regulating Hypoxia-induced Contractile Events in Pulmonary Endothelium American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2011 | Pubmed ID: 21378023 An Unexpected Role for the Clock Protein Timeless in Developmental Apoptosis PloS One. 2011 | Pubmed ID: 21359199 Intratumoral IL-12 Gene Therapy Results in the Crosspriming of Tc1 Cells Reactive Against Tumor-associated Stromal Antigens Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2011 | Pubmed ID: 21189473 Sunitinib Facilitates the Activation and Recruitment of Therapeutic Anti-tumor Immunity in Concert with Specific Vaccination International Journal of Cancer. Journal International Du Cancer. Nov, 2011 | Pubmed ID: 21170961 Accelerated Aging of Intervertebral Discs in a Mouse Model of Progeria Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2010 | Pubmed ID: 20973062 The Second Extracellular Loop Dictates Occludin-mediated HCV Entry Virology. Nov, 2010 | Pubmed ID: 20822789 Identification of a Cardiac Specific Protein Transduction Domain by in Vivo Biopanning Using a M13 Phage Peptide Display Library in Mice PloS One. 2010 | Pubmed ID: 20808875 Sar1 Assembly Regulates Membrane Constriction and ER Export The Journal of Cell Biology. Jul, 2010 | Pubmed ID: 20624903 Virally Infected and Matured Human Dendritic Cells Activate Natural Killer Cells Via Cooperative Activity of Plasma Membrane-bound TNF and IL-15 Blood. Jul, 2010 | Pubmed ID: 20430958 Inhibition and Role of Let-7d in Idiopathic Pulmonary Fibrosis American Journal of Respiratory and Critical Care Medicine. Jul, 2010 | Pubmed ID: 20395557 Deregulation of Mitochondrial Membrane Potential by Mitochondrial Insertion of Granzyme B and Direct Hax-1 Cleavage The Journal of Biological Chemistry. Jul, 2010 | Pubmed ID: 20388708 Characterization of an Lhx1a Transgenic Reporter in Zebrafish The International Journal of Developmental Biology. 2010 | Pubmed ID: 20209443 DC Expressing Transgene Foxp3 Are Regulatory APC European Journal of Immunology. Feb, 2010 | Pubmed ID: 19941313 Biochemical Isolation and Characterization of the Tubulovesicular LC3-positive Autophagosomal Compartment The Journal of Biological Chemistry. Jan, 2010 | Pubmed ID: 19910472 IL-6 Adsorption Dynamics in Hemoadsorption Beads Studied Using Confocal Laser Scanning Microscopy Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Feb, 2010 | Pubmed ID: 19904819 AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells American Journal of Respiratory Cell and Molecular Biology. Jun, 2010 | Pubmed ID: 19617399 Stratification of Antigen-presenting Cells Within the Normal Cornea Ophthalmology and Eye Diseases. Nov, 2009 | Pubmed ID: 20431695 Structural Requirements for PACSIN/Syndapin Operation During Zebrafish Embryonic Notochord Development PloS One. 2009 | Pubmed ID: 19997509 Ectopic T-bet Expression Licenses Dendritic Cells for IL-12-independent Priming of Type 1 T Cells in Vitro Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009 | Pubmed ID: 19915058 HIV-1 Infection of DC: Evidence for the Acquisition of Virus Particles from Infected T Cells by Antigen Uptake Mechanism PloS One. 2009 | Pubmed ID: 19829715 WITHDRAWN: Communication Between Immune Cells Mediated by Membrane Connections Immunology Letters. Oct, 2009 | Pubmed ID: 19808050 Dendritic Cell Altered States: What Role for Calcium? Immunological Reviews. Sep, 2009 | Pubmed ID: 19754904 Using Total Internal Reflection Fluorescence (TIRF) Microscopy to Visualize Cortical Actin and Microtubules in the Drosophila Syncytial Embryo Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2009 | Pubmed ID: 19718762 Cholesterol-dependent Cytolysins Induce Rapid Release of Mature IL-1beta from Murine Macrophages in a NLRP3 Inflammasome and Cathepsin B-dependent Manner Journal of Leukocyte Biology. Nov, 2009 | Pubmed ID: 19675207 The Tubulin-like RepX Protein Encoded by the PXO1 Plasmid Forms Polymers in Vivo in Bacillus Anthracis Journal of Bacteriology. Apr, 2009 | Pubmed ID: 19233922 Noncytotoxic Suppression of Human Immunodeficiency Virus Type 1 Transcription by Exosomes Secreted from CD8+ T Cells Journal of Virology. May, 2009 | Pubmed ID: 19193788 Effective Immunotherapy Against Murine Gliomas Using Type 1 Polarizing Dendritic Cells--significant Roles of CXCL10 Cancer Research. Feb, 2009 | Pubmed ID: 19190335 Differential Capability of Human Cutaneous Dendritic Cell Subsets to Initiate Th17 Responses Journal of Immunology (Baltimore, Md. : 1950). Jan, 2009 | Pubmed ID: 19124735 Starving Neurons Show Sex Difference in Autophagy The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 19036730 P38-MAPK- and Caspase-3-mediated Superoxide-induced Apoptosis of Rat Hepatic Stellate Cells: Reversal by Retinoic Acid Journal of Cellular Physiology. Jan, 2009 | Pubmed ID: 18792915 The AP-2 Adaptor Beta2 Appendage Scaffolds Alternate Cargo Endocytosis Molecular Biology of the Cell. Dec, 2008 | Pubmed ID: 18843039 Fatty Acid Synthase is Up-regulated During Hepatitis C Virus Infection and Regulates Hepatitis C Virus Entry and Production Hepatology (Baltimore, Md.). Nov, 2008 | Pubmed ID: 18830996 CD8+ T-cell Responses Against Hemoglobin-beta Prevent Solid Tumor Growth Cancer Research. Oct, 2008 | Pubmed ID: 18829566 CX3CL1 Up-regulation is Associated with Recruitment of CX3CR1+ Mononuclear Phagocytes and T Lymphocytes in the Lungs During Cigarette Smoke-induced Emphysema The American Journal of Pathology. Oct, 2008 | Pubmed ID: 18772344 Nitric-oxide-mediated Zinc Release Contributes to Hypoxic Regulation of Pulmonary Vascular Tone Circulation Research. Jun, 2008 | Pubmed ID: 18483408 Chemokine and Cytokine Mediated Loss of Regulatory T Cells in Lymph Nodes During Pathogenic Simian Immunodeficiency Virus Infection Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18390737 Spatiotemporal Response of Living Cell Structures in Dictyostelium Discoideum with Semiconductor Quantum Dots Nano Letters. May, 2008 | Pubmed ID: 18386936 Protein Kinase C Alpha and Zeta Differentially Regulate Death-inducing Signaling Complex Formation in Cigarette Smoke Extract-induced Apoptosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2008 | Pubmed ID: 18354190 Memory CD8+ T Cells Protect Dendritic Cells from CTL Killing Journal of Immunology (Baltimore, Md. : 1950). Mar, 2008 | Pubmed ID: 18322193 Exosomes As a Short-range Mechanism to Spread Alloantigen Between Dendritic Cells During T Cell Allorecognition Journal of Immunology (Baltimore, Md. : 1950). Mar, 2008 | Pubmed ID: 18292531 Augmenter of Liver Regeneration: an Important Intracellular Survival Factor for Hepatocytes Journal of Hepatology. Apr, 2008 | Pubmed ID: 18272248 Mitogen-activated Protein Kinases Regulate Susceptibility to Ventilator-induced Lung Injury PloS One. 2008 | Pubmed ID: 18270588 Correlation of the Tight Junction-like Distribution of Claudin-1 to the Cellular Tropism of Hepatitis C Virus The Journal of Biological Chemistry. Mar, 2008 | Pubmed ID: 18211898 GTP-dependent Polymerization of the Tubulin-like RepX Replication Protein Encoded by the PXO1 Plasmid of Bacillus Anthracis Molecular Microbiology. Feb, 2008 | Pubmed ID: 18179418 Sequences in Intron 51 of the Von Willebrand Factor Gene Target Promoter Activation to a Subset of Lung Endothelial Cells in Transgenic Mice The Journal of Biological Chemistry. Feb, 2008 | Pubmed ID: 18048367 Identification of Poly-ADP-ribosylated Mitochondrial Proteins After Traumatic Brain Injury Journal of Neurochemistry. Mar, 2008 | Pubmed ID: 17996029 Virologic and Immunologic Events in Hilar Lymph Nodes During Simian Immunodeficiency Virus Infection: Development of Polarized Inflammation Journal of Acquired Immune Deficiency Syndromes (1999). Jan, 2008 | Pubmed ID: 17971706 Autophagy is Increased in Mice After Traumatic Brain Injury and is Detectable in Human Brain After Trauma and Critical Illness Autophagy. Jan, 2008 | Pubmed ID: 17957135 Autophagy is Increased After Traumatic Brain Injury in Mice and is Partially Inhibited by the Antioxidant Gamma-glutamylcysteinyl Ethyl Ester Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2008 | Pubmed ID: 17786151 Potential Solutions for Confocal Imaging of Living Animals BioTechniques. Jul, 2007 | Pubmed ID: 17933097 An Intracellular Serpin Regulates Necrosis by Inhibiting the Induction and Sequelae of Lysosomal Injury Cell. Sep, 2007 | Pubmed ID: 17889653 Distinct Intracellular Trafficking of Equine Infectious Anemia Virus and Human Immunodeficiency Virus Type 1 Gag During Viral Assembly and Budding Revealed by Bimolecular Fluorescence Complementation Assays Journal of Virology. Oct, 2007 | Pubmed ID: 17686839 Generation of FGF Reporter Transgenic Zebrafish and Their Utility in Chemical Screens BMC Developmental Biology. 2007 | Pubmed ID: 17553162 Association of Gag Multimers with Filamentous Actin During Equine Infectious Anemia Virus Assembly Current HIV Research. May, 2007 | Pubmed ID: 17504173 Golgi-associated Maturation of Very Low Density Lipoproteins Involves Conformational Changes in Apolipoprotein B, but is Not Dependent on Apolipoprotein E The Journal of Biological Chemistry. Jul, 2007 | Pubmed ID: 17500069 Gliotoxin Causes Apoptosis and Necrosis of Rat Kupffer Cells in Vitro and in Vivo in the Absence of Oxidative Stress: Exacerbation by Caspase and Serine Protease Inhibition Journal of Hepatology. Jul, 2007 | Pubmed ID: 17466404 Treatment-enhanced CD4+Foxp3+ Glucocorticoid-induced TNF Receptor Family Related High Regulatory Tumor-infiltrating T Cells Limit the Effectiveness of Cytokine-based Immunotherapy Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007 | Pubmed ID: 17339434 Testosterone Activates Mitogen-activated Protein Kinase Via Src Kinase and the Epidermal Growth Factor Receptor in Sertoli Cells Endocrinology. May, 2007 | Pubmed ID: 17272394 The Hsp40 Molecular Chaperone Ydj1p, Along with the Protein Kinase C Pathway, Affects Cell-wall Integrity in the Yeast Saccharomyces Cerevisiae Genetics. Apr, 2007 | Pubmed ID: 17237519 Mitochondrial Localization and Function of Heme Oxygenase-1 in Cigarette Smoke-induced Cell Death American Journal of Respiratory Cell and Molecular Biology. Apr, 2007 | Pubmed ID: 17079780 Boc-Aspartyl(OMe)-fluoromethylketone Attenuates Mitochondrial Release of Cytochrome C and Delays Brain Tissue Loss After Traumatic Brain Injury in Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2007 | Pubmed ID: 16736044 Dynamic Properties of Antigen Uptake and Communication Between Dendritic Cells Immunologic Research. 2006 | Pubmed ID: 17337781 Phagocytosis Induces Lysosome Remodeling and Regulated Presentation of Particulate Antigens by Activated Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Dec, 2006 | Pubmed ID: 17142747 Proteolysis Consistent with Activation of Caspase-7 After Severe Traumatic Brain Injury in Humans Journal of Neurotrauma. Nov, 2006 | Pubmed ID: 17115905 Phosphatidylinositol 4-phosphate Formation at ER Exit Sites Regulates ER Export Developmental Cell. Nov, 2006 | Pubmed ID: 17084359 The Beta-delta-core of Sarcoglycan is Essential for Deposition at the Plasma Membrane Muscle & Nerve. Dec, 2006 | Pubmed ID: 17036316 Cell-surface Protein Disulfide Isomerase is Required for Transnitrosation of Metallothionein by S-nitroso-albumin in Intact Rat Pulmonary Vascular Endothelial Cells Experimental Biology and Medicine (Maywood, N.J.). Oct, 2006 | Pubmed ID: 17018873 Autophagy is Induced in CD4+ T Cells and Important for the Growth Factor-withdrawal Cell Death Journal of Immunology (Baltimore, Md. : 1950). Oct, 2006 | Pubmed ID: 17015701 Intravital Fluorescence Microscopy in Pulmonary Research Advanced Drug Delivery Reviews. Sep, 2006 | Pubmed ID: 16996641 Comprehensive Analysis of Gene Expression on GOLD-2 Versus GOLD-0 Smokers Reveals Novel Genes Important in the Pathogenesis of COPD Proceedings of the American Thoracic Society. Aug, 2006 | Pubmed ID: 16921106 Rapid Adaptation of a Recombinant Vesicular Stomatitis Virus to a Targeted Cell Line Journal of Virology. Sep, 2006 | Pubmed ID: 16912309 Mechanisms of Endotoxin-induced NO, IL-6, and TNF-alpha Production in Activated Rat Hepatic Stellate Cells: Role of P38 MAPK Hepatology (Baltimore, Md.). Aug, 2006 | Pubmed ID: 16871588 A Single Common Portal for Clathrin-mediated Endocytosis of Distinct Cargo Governed by Cargo-selective Adaptors Molecular Biology of the Cell. Oct, 2006 | Pubmed ID: 16870701 DC-SIGN on B Lymphocytes is Required for Transmission of HIV-1 to T Lymphocytes PLoS Pathogens. Jul, 2006 | Pubmed ID: 16839201 Spatial Localization of M-calpain to the Plasma Membrane by Phosphoinositide Biphosphate Binding During Epidermal Growth Factor Receptor-mediated Activation Molecular and Cellular Biology. Jul, 2006 | Pubmed ID: 16809781 Alpha-sarcoglycan is Recycled from the Plasma Membrane in the Absence of Sarcoglycan Complex Assembly Traffic (Copenhagen, Denmark). Jul, 2006 | Pubmed ID: 16787395 Transgenic Galectin-1 Induces Maturation of Dendritic Cells That Elicit Contrasting Responses in Naive and Activated T Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2006 | Pubmed ID: 16751364 Mycoplasma Fermentans and TNF-beta Interact to Amplify Immune-modulating Cytokines in Human Lung Fibroblasts American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2006 | Pubmed ID: 16751226 Polysomes Are Associated with Microtubules in Fertilized Eggs of Chinese Pine (Pinus Tabulaeformis) Protoplasma. May, 2006 | Pubmed ID: 16736260 Combinational FLt3 Ligand and Granulocyte Macrophage Colony-stimulating Factor Treatment Promotes Enhanced Tumor Infiltration by Dendritic Cells and Antitumor CD8(+) T-cell Cross-priming but is Ineffective As a Therapy Cancer Research. May, 2006 | Pubmed ID: 16651446 Gene Expression Profiling of Target Genes in Ventilator-induced Lung Injury Physiological Genomics. Jun, 2006 | Pubmed ID: 16569776 The NPM-RAR Fusion Protein Associated with the T(5;17) Variant of APL Does Not Interact with PML Leukemia Research. Aug, 2006 | Pubmed ID: 16504291 Epsin 1 is a Polyubiquitin-selective Clathrin-associated Sorting Protein Traffic (Copenhagen, Denmark). Mar, 2006 | Pubmed ID: 16497222 Mini-dystrophin Efficiently Incorporates into the Dystrophin Protein Complex in Living Cells Journal of Muscle Research and Cell Motility. 2006 | Pubmed ID: 16496225 DC-SIGN is a Receptor for Human Herpesvirus 8 on Dendritic Cells and Macrophages Journal of Immunology (Baltimore, Md. : 1950). Feb, 2006 | Pubmed ID: 16424204 Guidance of Engineered Tissue Collagen Orientation by Large-scale Scaffold Microstructures Journal of Biomechanics. 2006 | Pubmed ID: 16043186 Confocal Microscopy: Comparisons, Applications, and Problems BioTechniques. Dec, 2005 | Pubmed ID: 20158500 Regulation of Sar1 NH2 Terminus by GTP Binding and Hydrolysis Promotes Membrane Deformation to Control COPII Vesicle Fission The Journal of Cell Biology. Dec, 2005 | Pubmed ID: 16344311 Fluorescence Resonance Energy Transfer-based Assays for the Real-time Detection of Nitric Oxide Signaling Methods in Enzymology. 2005 | Pubmed ID: 16291241 Tumor Cell Loaded Type-1 Polarized Dendritic Cells Induce Th1-mediated Tumor Immunity Cancer Research. Nov, 2005 | Pubmed ID: 16267032 Improvement of Human Lysozyme Expression in Transgenic Rice Grain by Combining Wheat (Triticum Aestivum) Puroindoline B and Rice (Oryza Sativa) Gt1 Promoters and Signal Peptides Transgenic Research. Oct, 2005 | Pubmed ID: 16245149 Nitric Oxide and Zinc Homeostasis in Acute Lung Injury Proceedings of the American Thoracic Society. 2005 | Pubmed ID: 16222044 IL-18-induced CD83+CCR7+ NK Helper Cells The Journal of Experimental Medicine. Oct, 2005 | Pubmed ID: 16203865 Functional Connectivity Between Immune Cells Mediated by Tunneling Nanotubules Immunity. Sep, 2005 | Pubmed ID: 16169503 Delivery of Dendritic Cells Engineered to Secrete IFN-alpha into Central Nervous System Tumors Enhances the Efficacy of Peripheral Tumor Cell Vaccines: Dependence on Apoptotic Pathways Journal of Immunology (Baltimore, Md. : 1950). Aug, 2005 | Pubmed ID: 16081851 Gene Transfer to Human Joints: Progress Toward a Gene Therapy of Arthritis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2005 | Pubmed ID: 15939878 Exosomes Derived from IL-10-treated Dendritic Cells Can Suppress Inflammation and Collagen-induced Arthritis Journal of Immunology (Baltimore, Md. : 1950). May, 2005 | Pubmed ID: 15879146 Epidermal Growth Factor Receptor-transfected Bone Marrow Stromal Cells Exhibit Enhanced Migratory Response and Therapeutic Potential Against Murine Brain Tumors Cancer Gene Therapy. Sep, 2005 | Pubmed ID: 15832173 Normal Rat Hepatic Stellate Cells Respond to Endotoxin in LBP-independent Manner to Produce Inhibitor(s) of DNA Synthesis in Hepatocytes Journal of Cellular Physiology. Aug, 2005 | Pubmed ID: 15828022 Dynamic Regulation of Tec Kinase Localization in Membrane-proximal Vesicles of a T Cell Clone Revealed by Total Internal Reflection Fluorescence and Confocal Microscopy The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15817477 The Characterization of Tumor Apoptosis After Experimental Radiosurgery Stereotactic and Functional Neurosurgery. 2005 | Pubmed ID: 15775705 Sulforaphane-induced Cell Death in Human Prostate Cancer Cells is Initiated by Reactive Oxygen Species The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15764812 Altered Trafficking of Fas and Subsequent Resistance to Fas-mediated Apoptosis Occurs by a Wild-type P53 Independent Mechanism in Esophageal Adenocarcinoma The Journal of Surgical Research. Feb, 2005 | Pubmed ID: 15680394 Physical and Functional Association of Migfilin with Cell-cell Adhesions Journal of Cell Science. Feb, 2005 | Pubmed ID: 15671069 Dynamics of Dendritic Cell Phenotype and Interactions with CD4+ T Cells in Airway Inflammation and Tolerance Journal of Immunology (Baltimore, Md. : 1950). Jan, 2005 | Pubmed ID: 15634907 Distinct Golgi Populations of Phosphatidylinositol 4-phosphate Regulated by Phosphatidylinositol 4-kinases The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15634669 Ectopic Expression of Interferon Regulatory Factor-1 Promotes Human Breast Cancer Cell Death and Results in Reduced Expression of Survivin Cancer Research. Nov, 2004 | Pubmed ID: 15548708 Nitric Oxide and Ionizing Radiation Synergistically Promote Apoptosis and Growth Inhibition of Cancer by Activating P53 Cancer Research. Nov, 2004 | Pubmed ID: 15520210 Gene Combination Transfer to Block Autoimmune Damage in Transplanted Islets of Langerhans Experimental Diabesity Research. Jul-Sep, 2004 | Pubmed ID: 15512788 Comprehensive Gene Expression Profiles Reveal Pathways Related to the Pathogenesis of Chronic Obstructive Pulmonary Disease Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004 | Pubmed ID: 15469929 Autocrine Activation by Interleukin 1alpha Induces the Fibrogenic Phenotype of Systemic Sclerosis Fibroblasts The Journal of Rheumatology. Oct, 2004 | Pubmed ID: 15468358 Signaling Via a Novel Integral Plasma Membrane Pool of a Serine/threonine Protein Kinase PRK1 in Mammalian Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2004 | Pubmed ID: 15375078 Beta-synemin Localizes to Regions of High Stress in Human Skeletal Myofibers Muscle & Nerve. Sep, 2004 | Pubmed ID: 15318345 Inhibition of Tumor Necrosis Factor Receptor-1-mediated Pathways Has Beneficial Effects in a Murine Model of Postischemic Remodeling American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2004 | Pubmed ID: 15317681 Delivery of Interferon-alpha Transfected Dendritic Cells into Central Nervous System Tumors Enhances the Antitumor Efficacy of Peripheral Peptide-based Vaccines Cancer Research. Aug, 2004 | Pubmed ID: 15313927 Nitric Oxide-induced Modification of Protein Thiolate Clusters As Determined by Spectral Fluorescence Resonance Energy Transfer in Live Endothelial Cells Free Radical Biology & Medicine. Sep, 2004 | Pubmed ID: 15304254 Redistribution of Pulmonary EC-SOD After Exposure to Asbestos Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2004 | Pubmed ID: 15298984 Endocytosis, Intracellular Sorting, and Processing of Exosomes by Dendritic Cells Blood. Nov, 2004 | Pubmed ID: 15284116 Disruption of Muscle Membrane and Phenotype Divergence in Two Novel Mouse Models of Dysferlin Deficiency Human Molecular Genetics. Sep, 2004 | Pubmed ID: 15254015 Innate Gender-based Proclivity in Response to Cytotoxicity and Programmed Cell Death Pathway The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15234982 Resolution of Anaphase Bridges in Cancer Cells Chromosoma. Jun, 2004 | Pubmed ID: 15156327 Role of the NH2 Terminus in the Assembly and Trafficking of the Intermediate Conductance Ca2+-activated K+ Channel HIK1 The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14754884 Escherichia Coli Expressing Recombinant Antigen and Listeriolysin O Stimulate Class I-restricted CD8+ T Cells Following Uptake by Human APC Journal of Immunology (Baltimore, Md. : 1950). Feb, 2004 | Pubmed ID: 14734740 Endocytic Adaptor Molecules Reveal an Endosomal Population of Clathrin by Total Internal Reflection Fluorescence Microscopy The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14722064 Cdk-inhibitors and Exit from Quiescence in Primitive Haematopoietic Cell Subsets British Journal of Haematology. Feb, 2004 | Pubmed ID: 14717785 Differential Effects of Actin Cytoskeleton Dynamics on Equine Infectious Anemia Virus Particle Production Journal of Virology. Jan, 2004 | Pubmed ID: 14694119 Rapid and Extensive Membrane Reorganization by Dendritic Cells Following Exposure to Bacteria Revealed by High-resolution Imaging Journal of Leukocyte Biology. Feb, 2004 | Pubmed ID: 14634062 Highly Efficient Expression of Transgenic Proteins by Naked DNA-transfected Dendritic Cells Through Terminal Differentiation Blood. Feb, 2004 | Pubmed ID: 14551149 Adenovirus-transduced Dendritic Cells Injected into Skin or Lymph Node Prime Potent Simian Immunodeficiency Virus-specific T Cell Immunity in Monkeys Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003 | Pubmed ID: 14662894 Vesicular Stomatitis Virus Expressing a Chimeric Sindbis Glycoprotein Containing an Fc Antibody Binding Domain Targets to Her2/neu Overexpressing Breast Cancer Cells Virology. Nov, 2003 | Pubmed ID: 14644615 Selective Toxicity of Engineered Lentivirus Lytic Peptides in a CF Airway Cell Model Peptides. Aug, 2003 | Pubmed ID: 14612179 Some Morphological, Growth, and Genomic Properties of Human Cells Chronically Infected with Porcine Endogenous Retrovirus (PERV) Genome / National Research Council Canada = Génome / Conseil National De Recherches Canada. Oct, 2003 | Pubmed ID: 14608403 Body Window-enabled in Vivo Multicolor Imaging of Transplanted Mouse Islets Expressing an Insulin-Timer Fusion Protein BioTechniques. Oct, 2003 | Pubmed ID: 14579736 Intratumoral Delivery of Dendritic Cells Engineered to Secrete Both Interleukin (IL)-12 and IL-18 Effectively Treats Local and Distant Disease in Association with Broadly Reactive Tc1-type Immunity Cancer Research. Oct, 2003 | Pubmed ID: 14559827 Activation of Phospholipase D by the Small GTPase Sar1p is Required to Support COPII Assembly and ER Export The EMBO Journal. Aug, 2003 | Pubmed ID: 12912905 Identification of a Synovial Fibroblast-specific Protein Transduction Domain for Delivery of Apoptotic Agents to Hyperplastic Synovium Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2003 | Pubmed ID: 12907152 Multimodal Optical Imaging American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2003 | Pubmed ID: 12851207 Aberrant Development of Motor Axons and Neuromuscular Synapses in MyoD-null Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003 | Pubmed ID: 12832540 Carbon Monoxide Induces Cytoprotection in Rat Orthotopic Lung Transplantation Via Anti-inflammatory and Anti-apoptotic Effects The American Journal of Pathology. Jul, 2003 | Pubmed ID: 12819027 Transforming Growth Factor Beta Blocks Tec Kinase Phosphorylation, Ca2+ Influx, and NFATc Translocation Causing Inhibition of T Cell Differentiation The Journal of Experimental Medicine. Jun, 2003 | Pubmed ID: 12810687 Directional Motility Induced by Epidermal Growth Factor Requires Cdc42 Experimental Cell Research. Jul, 2003 | Pubmed ID: 12799181 Elevated Hepatocyte Levels of the Forkhead Box A2 (HNF-3beta) Transcription Factor Cause Postnatal Steatosis and Mitochondrial Damage Hepatology (Baltimore, Md.). Jun, 2003 | Pubmed ID: 12774021 Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/bid Pathway The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12754217 Caspase-8 Expression and Proteolysis in Human Brain After Severe Head Injury FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2003 | Pubmed ID: 12738800 Inducible Expression of Keratinocyte Growth Factor (KGF) in Mice Inhibits Lung Epithelial Cell Death Induced by Hyperoxia Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12732722 Tumor-localization by Adoptively Transferred, Interleukin-2-activated NK Cells Leads to Destruction of Well-established Lung Metastases International Journal of Cancer. Journal International Du Cancer. Jul, 2003 | Pubmed ID: 12712443 Localization of the BiP Molecular Chaperone with Respect to Endoplasmic Reticulum Foci Containing the Cystic Fibrosis Transmembrane Conductance Regulator in Yeast The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Apr, 2003 | Pubmed ID: 12642634 Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12626504 Cellular Mechanisms of Interleukin-12-mediated Neuroblastoma Regression Journal of Pediatric Surgery. Feb, 2003 | Pubmed ID: 12596103 A Role for Class A Scavenger Receptor in Dendritic Cell Nibbling from Live Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2003 | Pubmed ID: 12594251 Characterization of the Expression of Inducible Nitric Oxide Synthase in Rat and Human Liver During Hemorrhagic Shock Shock (Augusta, Ga.). Feb, 2003 | Pubmed ID: 12578118 Dendritic Cells Transduced to Express Interleukin-4 Prevent Diabetes in Nonobese Diabetic Mice with Advanced Insulitis Human Gene Therapy. Jan, 2003 | Pubmed ID: 12573055 Expression and Localization of Human Lysozyme in the Endosperm of Transgenic Rice Planta. Feb, 2003 | Pubmed ID: 12569401 Alterations in Inducible 72-kDa Heat Shock Protein and the Chaperone Cofactor BAG-1 in Human Brain After Head Injury Journal of Neurochemistry. Feb, 2003 | Pubmed ID: 12558971 Gene Transfer of Manganese Superoxide Dismutase Extends Islet Graft Function in a Mouse Model of Autoimmune Diabetes Diabetes. Feb, 2003 | Pubmed ID: 12540612 Identification of C-kit-positive Cells in the Mouse Ureter: the Interstitial Cells of Cajal of the Urinary Tract American Journal of Physiology. Renal Physiology. May, 2003 | Pubmed ID: 12540363 Vascularization and Tissue Infiltration of a Biodegradable Polyurethane Matrix Journal of Biomedical Materials Research. Part A. Feb, 2003 | Pubmed ID: 12522810 Trafficking of the Ca2+-activated K+ Channel, HIK1, is Dependent Upon a C-terminal Leucine Zipper The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12493744 Internalization of Circulating Apoptotic Cells by Splenic Marginal Zone Dendritic Cells: Dependence on Complement Receptors and Effect on Cytokine Production Blood. Jan, 2003 | Pubmed ID: 12393562 Chronic Exposure to Interleukin 1beta Induces a Delayed and Reversible Alteration in Excitation-contraction Coupling of Cultured Cardiomyocytes Pflügers Archiv : European Journal of Physiology. Nov, 2002 | Pubmed ID: 12457245 The Autosomal Recessive Hypercholesterolemia (ARH) Protein Interfaces Directly with the Clathrin-coat Machinery Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12451172 CYR61 (CCN1) is Essential for Placental Development and Vascular Integrity Molecular and Cellular Biology. Dec, 2002 | Pubmed ID: 12446788 Local Administration of IL-12-transfected Dendritic Cells Induces Antitumor Immune Responses to Colon Adenocarcinoma in the Liver in Mice Journal of Experimental Therapeutics & Oncology. Nov-Dec, 2002 | Pubmed ID: 12440225 Disabled-2 Exhibits the Properties of a Cargo-selective Endocytic Clathrin Adaptor The EMBO Journal. Sep, 2002 | Pubmed ID: 12234931 Depletion of Pulmonary EC-SOD After Exposure to Hyperoxia American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2002 | Pubmed ID: 12225954 Hepatocyte Fas-associating Death Domain Protein/mediator of Receptor-induced Toxicity (FADD/MORT1) Levels Increase in Response to Pro-apoptotic Stimuli The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12167637 Effect of Immunosuppressive Agents on Glucocorticoid Receptor Function in A6 Cells American Journal of Physiology. Renal Physiology. Aug, 2002 | Pubmed ID: 12110508 Intranuclear Localization of Apoptosis-inducing Factor (AIF) and Large Scale DNA Fragmentation After Traumatic Brain Injury in Rats and in Neuronal Cultures Exposed to Peroxynitrite Journal of Neurochemistry. Jul, 2002 | Pubmed ID: 12091479 Peroxisomal Localization of Inducible Nitric Oxide Synthase in Hepatocytes Hepatology (Baltimore, Md.). Jul, 2002 | Pubmed ID: 12085352 Efficiency of Protein Transduction is Cell Type-dependent and is Enhanced by Dextran Sulfate The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12034749 Nerve Growth Factor-induced Differentiation Changes the Cellular Organization of Regulated Peptide Release by PC12 Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 12019308 Wild-type Levels of the Mouse Forkhead Box F1 Gene Are Essential for Lung Repair American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2002 | Pubmed ID: 12003781 Murine Dendritic Cell-induced Tumor Apoptosis is Partially Mediated by Nitric Oxide Journal of Immunotherapy (Hagerstown, Md. : 1997). May-Jun, 2002 | Pubmed ID: 12000864 Distribution of Gelsolin and Phosphoinositol 4,5-bisphosphate in Lamellipodia During EGF-induced Motility The International Journal of Biochemistry & Cell Biology. Jul, 2002 | Pubmed ID: 11950594 Role of Glutathione Conjugate Efflux in Cellular Protection Against Benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA Damage Molecular Carcinogenesis. Mar, 2002 | Pubmed ID: 11870881 Induction of Anti-human Immunodeficiency Virus Type 1 (HIV-1) CD8(+) and CD4(+) T-cell Reactivity by Dendritic Cells Loaded with HIV-1 X4-infected Apoptotic Cells Journal of Virology. Mar, 2002 | Pubmed ID: 11861866 Platelet-endothelial Cell Adhesion Molecule-1-directed Immunotargeting to Cardiopulmonary Vasculature The Journal of Pharmacology and Experimental Therapeutics. Mar, 2002 | Pubmed ID: 11861781 The Modulation of Hepatic Injury and Heat Shock Expression by Inhibition of Inducible Nitric Oxide Synthase After Hemorrhagic Shock Shock (Augusta, Ga.). Jan, 2002 | Pubmed ID: 11795663 गतिशील सहभागिता की 3 डी स्ट्रक्चरल विश्लेषण के लिए correlative माइक्रोस्कोपी Sangmi Jun1, Gongpu Zhao1, Jiying Ning1, Gregory A. Gibson2, Simon C. Watkins2, Peijun Zhang1 1Department of Structural Biology, University of Pittsburgh School of Medicine, 2Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine JoVE 50386 Bioengineering बैक्टीरियल विष प्रेरित लाइव सेल प्रतिदीप्ति माइक्रोस्कोपी का उपयोग प्रतिक्रियाएँ की विज़ुअलाइज़ेशन Peter A. Keyel1, Michelle E. Heid1, Simon C. Watkins2, Russell D. Salter1 1Department of Immunology, University of Pittsburgh School of Medicine, 2Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine JoVE 4227 Immunology and Infection
गतिशील सहभागिता की 3 डी स्ट्रक्चरल विश्लेषण के लिए correlative माइक्रोस्कोपी Sangmi Jun1, Gongpu Zhao1, Jiying Ning1, Gregory A. Gibson2, Simon C. Watkins2, Peijun Zhang1 1Department of Structural Biology, University of Pittsburgh School of Medicine, 2Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine JoVE 50386 Bioengineering
बैक्टीरियल विष प्रेरित लाइव सेल प्रतिदीप्ति माइक्रोस्कोपी का उपयोग प्रतिक्रियाएँ की विज़ुअलाइज़ेशन Peter A. Keyel1, Michelle E. Heid1, Simon C. Watkins2, Russell D. Salter1 1Department of Immunology, University of Pittsburgh School of Medicine, 2Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine JoVE 4227 Immunology and Infection
