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In JoVE (1)
Other Publications (5)
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Articles by Stephan Diedrich in JoVE
बृहदान्त्र पेरिटोनिटिस (CASP) स्टेंट Ascendens - Polymicrobial पेट पूति के लिए एक मानकीकृत मॉडल
Tobias Traeger*, Pia Koerner*, Wolfram Kessler, Katharina Cziupka, Stephan Diedrich, Alexandra Busemann, Claus-Dieter Heidecke, Stefan Maier
Department of Surgery, University of Greifswald
Colon Ascendens पेरिटोनिटिस स्टेंट (CASP) कृन्तकों में polymicrobial पेट की पूति के लिए एक अत्यधिक मानकीकृत मॉडल है. यह लेख CASP की शल्य चिकित्सा की प्रक्रिया का वर्णन करता है. CASP मॉडल और इसके वेरिएंट पूति के विषय से संबंधित विभिन्न समस्याओं की व्यवस्थित जांच की अनुमति देते हैं.
Other articles by Stephan Diedrich on PubMed
Critical Care (London, England). 2006 | Pubmed ID: 17101035
Successful treatment of severe sepsis and septic shock remains a major challenge in critical care medicine. The recently introduced recombinant human activated protein C (APC) remarkably improved the outcome of septic patients. The influence of APC on intestinal circulation is still poorly understood. Therefore, the present study aimed to investigate the effects of APC on intestinal microcirculation during experimental endotoxaemia in rats by using intravital microscopy.
Kupffer Cell Depletion Reduces Hepatic Inflammation and Apoptosis but Decreases Survival in Abdominal Sepsis
European Journal of Gastroenterology & Hepatology. Sep, 2010 | Pubmed ID: 20300005
During abdominal sepsis, the activation of hepatic Kupffer cells (KC) and its consequences are of central interest. This study evaluates the impact of selective KC depletion on hepatic microcirculation, cytokine release, and systemic alterations in the colon ascendens stent peritonitis (CASP), a model of polymicrobial abdominal sepsis.
Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Nov, 2010 | Pubmed ID: 20577759
The aim of this study was to evaluate the feasibility, morbidity, and cost-effectiveness of the closure of the appendicular stump with a single non-absorbable polymeric clip compared with the closure of the appendicular stump with a stapler.
Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Improves the Innate Immune Response and Enhances Survival in Murine Polymicrobial Sepsis
Critical Care Medicine. Nov, 2010 | Pubmed ID: 20657274
To investigate the role of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in postoperative polymicrobial abdominal sepsis.Sepsis is the leading cause of death among critically ill surgical patients. TRAIL is commonly known as an apoptosis-inducing agent in cancer cells. It also plays an important role in the regulation of inflammatory reactions. The role of TRAIL in polymicrobial sepsis is still unclear.
In Vivo Imaging of Pancreatic Tumours and Liver Metastases Using 7 Tesla MRI in a Murine Orthotopic Pancreatic Cancer Model and a Liver Metastases Model
BMC Cancer. 2011 | Pubmed ID: 21276229
Pancreatic cancer is the fourth leading cause of tumour death in the western world. However, appropriate tumour models are scarce. Here we present a syngeneic murine pancreatic cancer model using 7 Tesla MRI and evaluate its clinical relevance and applicability.