Susan K. Buchanan National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institutes of Health Biography Publications Institution JoVE Articles Susan K. Buchanan has not added a biography. If you are Susan K. Buchanan and would like to personalize this page please email our Author Liaison for assistance. Publications Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens Structure (London, England : 1993). Jun, 2016 | Pubmed ID: 27161977 The Structure of the β-barrel Assembly Machinery Complex Science (New York, N.Y.). Jan, 2016 | Pubmed ID: 26744406 Summary and Future Directions Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26427693 Methods to Characterize Folding and Function of BamA Cross-Link Mutants Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26427681 Heat Modifiability of Outer Membrane Proteins from Gram-Negative Bacteria Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26427675 Fitting the Pieces of the β-Barrel Assembly Machinery Complex Biochemistry. Oct, 2015 | Pubmed ID: 26394220 Outer Membrane Protein Biogenesis in Gram-negative Bacteria Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Oct, 2015 | Pubmed ID: 26370935 Beyond the Crystal Structure: Insight into the Function and Vaccine Potential of TbpA Expressed by Neisseria Gonorrhoeae Infection and Immunity. Nov, 2015 | Pubmed ID: 26351283 Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40 The Journal of Biological Chemistry. Oct, 2015 | Pubmed ID: 26336107 The β-barrel Membrane Protein Insertase Machinery from Gram-negative Bacteria Current Opinion in Structural Biology. Apr, 2015 | Pubmed ID: 25796031 Reconstitution of a Nanomachine Driving the Assembly of Proteins into Bacterial Outer Membranes Nature Communications. 2014 | Pubmed ID: 25341963 Lateral Opening and Exit Pore Formation Are Required for BamA Function Structure (London, England : 1993). Jul, 2014 | Pubmed ID: 24980798 FhaC Takes a Bow to FHA in the Two-partner Do-si-do Molecular Microbiology. Jun, 2014 | Pubmed ID: 24798489 An Engineered Palette of Metal Ion Quenchable Fluorescent Proteins PloS One. 2014 | Pubmed ID: 24752441 Structural Insights into the Transport of Small Molecules Across Membranes Current Opinion in Structural Biology. Aug, 2014 | Pubmed ID: 24681594 Structural Insight into the Biogenesis of β-barrel Membrane Proteins Nature. Sep, 2013 | Pubmed ID: 23995689 Molecular Insight into Substrate Recognition and Catalysis of Baeyer-Villiger Monooxygenase MtmOIV, the Key Frame-modifying Enzyme in the Biosynthesis of Anticancer Agent Mithramycin ACS Chemical Biology. Nov, 2013 | Pubmed ID: 23992662 Integrated Nonlinear Optical Imaging Microscope for On-axis Crystal Detection and Centering at a Synchrotron Beamline Journal of Synchrotron Radiation. Jul, 2013 | Pubmed ID: 23765294 Structural Insight into the Lactoferrin Receptors from Pathogenic Neisseria Journal of Structural Biology. Oct, 2013 | Pubmed ID: 23462098 Specific Targeting and Killing of Gram-negative Pathogens with an Engineered Phage Lytic Enzyme Virulence. Jan, 2013 | Pubmed ID: 23314572 Using a Bacteriocin Structure to Engineer a Phage Lysin That Targets Yersinia Pestis Biochemical Society Transactions. Dec, 2012 | Pubmed ID: 23176506 The Transferrin-iron Import System from Pathogenic Neisseria Species Molecular Microbiology. Oct, 2012 | Pubmed ID: 22957710 Dynamic Association of BAM Complex Modules Includes Surface Exposure of the Lipoprotein BamC Journal of Molecular Biology. Sep, 2012 | Pubmed ID: 22683355 Structural Engineering of a Phage Lysin That Targets Gram-negative Pathogens Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012 | Pubmed ID: 22679291 Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. Coli and Enteropathogenic Y. Pseudotuberculosis Structure (London, England : 1993). Jul, 2012 | Pubmed ID: 22658748 Structural Basis for Iron Piracy by Pathogenic Neisseria Nature. Mar, 2012 | Pubmed ID: 22327295 Molecular Basis for the Activation of a Catalytic Asparagine Residue in a Self-cleaving Bacterial Autotransporter Journal of Molecular Biology. Jan, 2012 | Pubmed ID: 22094314 Structural Insights into the Catalytic Mechanism of Escherichia Coli Selenophosphate Synthetase Journal of Bacteriology. Jan, 2012 | Pubmed ID: 22081394 Structural Insights into Ail-mediated Adhesion in Yersinia Pestis Structure (London, England : 1993). Nov, 2011 | Pubmed ID: 22078566 Role of the Yersinia Pestis Ail Protein in Preventing a Protective Polymorphonuclear Leukocyte Response During Bubonic Plague Infection and Immunity. Dec, 2011 | Pubmed ID: 21969002 The Structural Biology of β-barrel Membrane Proteins: a Summary of Recent Reports Current Opinion in Structural Biology. Aug, 2011 | Pubmed ID: 21719274 The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21561854 The Crystal Structure of BamB Suggests Interactions with BamA and Its Role Within the BAM Complex Journal of Molecular Biology. Mar, 2011 | Pubmed ID: 21277859 Ancestral and Derived Protein Import Pathways in the Mitochondrion of Reclinomonas Americana Molecular Biology and Evolution. May, 2011 | Pubmed ID: 21081480 Solute and Ion Transport: Outer Membrane Pores and Receptors EcoSal Plus. Sep, 2010 | Pubmed ID: 26443780 TonB-dependent Transporters: Regulation, Structure, and Function Annual Review of Microbiology. 2010 | Pubmed ID: 20420522 Reconstitution of Bacterial Outer Membrane TonB-dependent Transporters in Planar Lipid Bilayer Membranes Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19959664 The Protein Import Channel in the Outer Mitosomal Membrane of Giardia Intestinalis Molecular Biology and Evolution. Sep, 2009 | Pubmed ID: 19531743 Protein Secretion and Outer Membrane Assembly in Alphaproteobacteria FEMS Microbiology Reviews. Nov, 2008 | Pubmed ID: 18759741 Signaling Mechanisms for Activation of Extracytoplasmic Function (ECF) Sigma Factors Biochimica Et Biophysica Acta. Sep, 2008 | Pubmed ID: 17673165 Crystallization of Integral Membrane Proteins Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [et Al.]. Feb, 2007 | Pubmed ID: 18429311 Autotransporter Structure Reveals Intra-barrel Cleavage Followed by Conformational Changes Nature Structural & Molecular Biology. Dec, 2007 | Pubmed ID: 17994105 Structure of Colicin I Receptor Bound to the R-domain of Colicin Ia: Implications for Protein Import The EMBO Journal. May, 2007 | Pubmed ID: 17464289 Colicin Biology Microbiology and Molecular Biology Reviews : MMBR. Mar, 2007 | Pubmed ID: 17347522 A Structural Comparison of Human Serum Transferrin and Human Lactoferrin Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine. Jun, 2007 | Pubmed ID: 17216400 The Crystal Structure of Iron-free Human Serum Transferrin Provides Insight into Inter-lobe Communication and Receptor Binding The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16793765 Bacterial Metal Detectors Molecular Microbiology. Dec, 2005 | Pubmed ID: 16313609 Recognition of Iron-free Siderophores by TonB-dependent Iron Transporters Molecular Microbiology. Oct, 2004 | Pubmed ID: 15458401 Structure of the OmpA-like Domain of RmpM from Neisseria Meningitidis Molecular Microbiology. Feb, 2004 | Pubmed ID: 14763978 Structural Evidence for Iron-free Citrate and Ferric Citrate Binding to the TonB-dependent Outer Membrane Transporter FecA Journal of Molecular Biology. Sep, 2003 | Pubmed ID: 12948487 Expression and Purification of Functional Recombinant Meningococcal Transferrin-binding Protein A The Biochemical Journal. Jun, 2002 | Pubmed ID: 11972452 From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins Nicholas Noinaj1, Stephen Mayclin2, Ann M. Stanley2,3, Christine C. Jao2,3, Susan K. Buchanan2 1Department of Biological Sciences, Markey Center for Structural Biology, Purdue University, 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, 3National Institute of General Medical Sciences (NIGMS), National Institutes of Health JoVE 53245 Chemistry
From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins Nicholas Noinaj1, Stephen Mayclin2, Ann M. Stanley2,3, Christine C. Jao2,3, Susan K. Buchanan2 1Department of Biological Sciences, Markey Center for Structural Biology, Purdue University, 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, 3National Institute of General Medical Sciences (NIGMS), National Institutes of Health JoVE 53245 Chemistry